Soothing and repairing composition and application thereof

Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to a soothing and repairing composition and application thereof. The soothing and repairing composition provided by the invention is prepared from the stephania tetrandra extract, the phoenix dactylifera fruit extract, the flower extract and the mirabilis jalapa extract through specific compatibility, and all the components generate a synergistic effect, so that the transdermal absorption of active ingredients can be remarkably enhanced; experimental data show that the composition can effectively improve the hyaluronidase inhibition rate and the TNF-alpha inhibition rate, and has excellent soothing and repairing effects; the preparation method of the composition is simple and convenient to operate and easy to realize industrial large-scale production, and has a good industrial application prospect; when the composition is applied to the essence, the TEWL value improvement rate and the a * value improvement rate of the essence can be remarkably improved, and the soothing and repairing effects are obvious; and human body patch test results of the essence show that the essence is mild and non-irritating, so that the composition disclosed by the invention has wide market application value in skin care products.

Description

Technical Field

[0001] This invention belongs to the field of cosmetic technology, specifically relating to a soothing and repairing composition and its application. Background Technology

[0002] As we age, the stratum corneum of the skin thins, weakening its protective function. Smoke, dust, UVA and UVB rays, as well as infrared radiation, can all generate free radicals that damage the skin's lipid barrier, thus harming the skin. Stress, mental tension, and low mood can also weaken the skin's natural resistance and reduce its self-repair function. Consumers are using cosmetics more frequently, and the probability of exposure to irritants is increasing accordingly, leading to a growing number of consumers experiencing thinning of the stratum corneum and damage to the skin barrier.

[0003] Currently, the number of people with sensitive skin is increasing daily, and both domestic and international markets are paying more and more attention to products with anti-allergy and repairing effects. Soothing and repairing products on the market often achieve their effects by eliminating alcohol, reducing the amount of preservatives, eliminating fragrances, and adding soothing and repairing ingredients. However, there are relatively few soothing and repairing cosmetics available, and due to individual differences—the causes of allergies vary from person to person—most products are not very effective and often lack immediate soothing and repairing effects.

[0004] As people pay more attention to health and quality of life, consumer demand for soothing and repairing cosmetics will continue to grow. Therefore, developing a gentle product with immediate soothing and repairing effects is one of the hottest research topics in the cosmetics industry. Summary of the Invention

[0005] In view of the above-mentioned defects or improvement needs of the prior art, the present invention provides a soothing and repairing composition and its application, which solves the problem of poor soothing and repairing effects of existing skin care products.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: In a first aspect, the present invention provides a soothing and repairing composition comprising, by weight percentage: 2%-10% Stephania tetrandra extract, 0.5%-2% jujube fruit extract, 1%-5% Sophora flavescens flower extract, 2%-6% Mirabilis jalapa extract, 25%-35% butylene glycol, 1.5%-3.5% 1,2-pentanediol, 1%-3% 1,2-hexanediol, with deionized water as the balance.

[0007] The Stephania tetrandra extract of this invention contains a variety of isoquinoline alkaloids, mainly including tetrandrine, fangchinorinine, and rotenone, among other active ingredients. It has excellent anti-inflammatory effects, inhibiting the proliferation and activation of inflammatory cells such as T lymphocytes, neutrophils, and monocytes / macrophages, resisting free radical damage, inhibiting the release of inflammatory mediators, or counteracting the effects of inflammatory mediators. At the same time, it has a good astringent effect on pores and can be used in skin-tightening cosmetics.

[0008] Date palm fruit extract is rich in gallic acid, caffeic acid, protocatechuic acid, quercetin glycoside, kaempferol-3-glucoside, and arabinogalactan, which have excellent moisturizing, soothing, antioxidant, and anti-glycation effects.

[0009] Jasmine flower extract is rich in jasmine flavonoids, which can effectively inhibit the release of pro-inflammatory mediators such as interleukin-1 and interleukin-8 that cause skin allergic reactions, enhance the skin cells' own defense system, and quickly soothe skin allergic symptoms. It has calming, antibacterial, moisturizing and anti-inflammatory effects.

[0010] Mirabilis jalapa extract can stimulate the secretion of key factors such as ceramides, occlusive proteins, and hyaluronic acid in the epidermis, improve the skin barrier function and water-locking ability, reduce inflammation and soothe the skin, and reduce facial redness. It can also inhibit the expression of the skin sensory nerve-related receptor TRPV1, and has highly effective antioxidant, moisturizing, anti-inflammatory, soothing and repairing effects, while being safe and gentle.

[0011] Preferably, the soothing and repairing composition comprises, by weight percentage: 5% Stephania tetrandra extract, 1% Date palm fruit extract, 3% Sophora flavescens flower extract, 3.5% Mirabilis jalapa extract, 30% Butylene glycol, 3% 1,2-pentanediol, 2% 1,2-hexanediol, with deionized water as the balance.

[0012] In a second aspect, the present invention provides a method for preparing the soothing and repairing composition described in the first aspect, comprising the following steps: weighing each component according to the formula amount, mixing the extracts of Stephania tetrandra, jujube fruit extract, senna flower extract, Mirabilis jalapa extract and deionized water evenly, adding butylene glycol, 1,2-pentanediol and 1,2-hexanediol, mixing evenly to obtain the soothing and repairing composition.

[0013] Thirdly, the present invention provides the use of the soothing and repairing composition described in the first aspect in the preparation of cosmetics, skin care products or washing and care products having soothing and repairing effects.

[0014] Preferably, the dosage form of the cosmetic is an aqueous solution, emulsion, or cream.

[0015] Preferably, the dosage form of the skin care product is a cream, lotion, liquid, gel, or mask.

[0016] Preferably, the dosage form of the washing and care product is an aqueous solution, emulsion, or cream.

[0017] More preferably, the cosmetic is any one of sunscreen, makeup base, primer, foundation, setting powder, concealer, contouring powder, or blush.

[0018] More preferably, the skincare product is any one of toner, lotion, cream, mask, or freeze-dried powder.

[0019] More preferably, the hair care product is any one of shampoo, hair mask, or shower gel.

[0020] The beneficial effects of this invention are: This invention provides a soothing and repairing composition, which is specifically formulated from extracts of Stephania tetrandra, jujube fruit, Senna alexandrina flower, and Mirabilis jalapa. The components exhibit a synergistic effect, significantly enhancing the transdermal absorption of the active ingredients. Experimental data show that this composition can effectively improve the inhibition rates of hyaluronidase and TNF-α, demonstrating excellent soothing and repairing effects. Furthermore, the preparation method of this composition is simple and easy to scale up for industrial production, showing promising prospects for industrial application.

[0021] The composition described in this invention can be widely used in skincare products. When added to serums, it can significantly improve the TEWL value and a* value improvement rate, and has a significant soothing and repairing effect. Furthermore, the human patch test results of the serum show that it is mild and non-irritating, indicating that the composition of this invention has broad market application value in skincare products. Detailed Implementation

[0022] To further illustrate the technical means and effects of the present invention in achieving the intended purpose, the following detailed description of the specific embodiments, structure, features and effects of the present invention, in conjunction with the composition, is provided below.

[0023] For the following compositions, unless otherwise specified, experimental methods are generally performed under standard conditions or as recommended by the manufacturer. Unless otherwise specified, all materials and reagents used are commercially available.

[0024] Some of the raw materials and their sources are as follows: The extract of Stephania tetrandra was purchased from Guangzhou Wentao Biotechnology Co., Ltd.; its properties are water-soluble. Date palm fruit extract was purchased from Guangzhou Wentao Biotechnology Co., Ltd.; Properties: water soluble; The extract of *Solanum nigrum* flower was purchased from Guangzhou Wentao Biotechnology Co., Ltd.; property: water soluble. The extract of Mirabilis jalapa was purchased from Guangzhou Wentao Biotechnology Co., Ltd.; its properties are water-soluble.

[0025] The component composition (mass percentage) of the soothing and repairing compositions in Examples 1-3 of this invention is shown in Table 1 below. Each component was weighed according to the formula amount. After mixing the extracts of Stephania tetrandra, jujube fruit extract, Susania serratifolia flower extract, Mirabilis jalapa extract and deionized water evenly, butylene glycol, 1,2-pentanediol and 1,2-hexanediol were added and mixed evenly to obtain each composition.

[0026] Table 1. Components and their mass percentages of the compositions in Examples 1-3 Example Stephania tetrandra extract (%) Date palm fruit extract (%) Sufang flower extract (%) Mirabilis jalapa extract (%) Butanediol (%) 1,2-Pentanediol (%) 1,2-Hexanediol (%) Deionized water (%) 1 2 0.5 5 6 25 3.5 3 margin 2 10 2 1 2 35 1.5 1 margin 3 5 1 3 3.5 30 3 2 margin Comparative Example 1 Compared with Example 3, the difference is that no Stephania tetrandra extract was added in Comparative Example 1, and the missing amount was made up by extracts of jujube fruit, Susania serratifolia flower, and Mirabilis jalapa in a mass ratio of 1:3:3.5. All other conditions and preparation methods were the same as in Example 3.

[0027] Comparative Example 2 Compared with Example 3, the difference is that no date fruit extract was added in Comparative Example 2, and the missing amount was made up by extracts of Stephania tetrandra, Sophora flavescens, and Mirabilis jalapa in a mass ratio of 5:3:3.5. All other conditions and preparation methods were the same as in Example 3.

[0028] Comparative Example 3 Compared with Example 3, the difference is that no extract of *Stephania tetrandra* flower was added in Comparative Example 3, and the missing amount was made up by extracts of *Stephania tetrandra*, *Ziziphus jujuba* fruit, and *Mirabilis jalapa* in a mass ratio of 5:1:3.5. All other conditions and preparation methods were the same as in Example 3.

[0029] Comparative Example 4 Compared with Example 3, the difference is that Mirabilis jalapa extract was not added in Comparative Example 4, and the missing amount was made up by extracts of Stephania tetrandra, jujube fruit extract and Sophora flavescens flower extract in a mass ratio of 5:1:3. All other conditions and preparation methods are the same as in Example 3.

[0030] Comparative Example 5 Compared with Example 3, the difference is that the mass ratio of Stephania tetrandra extract, jujube fruit extract, Sophora flavescens flower extract and Mirabilis jalapa extract in Comparative Example 5 is 1:5:3:3.5, while other conditions and preparation methods are the same as in Example 3.

[0031] Comparative Example 6 Compared with Example 3, the difference is that the weight ratio of Stephania tetrandra extract, jujube fruit extract, Sophora flavescens flower extract and Mirabilis jalapa extract in Comparative Example 6 is 5:3:1:3.5, while other conditions and preparation methods are the same as in Example 3.

[0032] Comparative Example 7 Compared with Example 3, the difference is that the weight ratio of Stephania tetrandra extract, jujube fruit extract, Sophora flavescens flower extract and Mirabilis jalapa extract in Comparative Example 7 is 5:3.5:3:1, while other conditions and preparation methods are the same as in Example 3.

[0033] Example 1 of efficacy test: Hyaluronidase inhibition rate test Hyaluronic acid is widely present in the skin and other tissues, and its relationship with the skin is very close. High-molecular-weight hyaluronic acid can inhibit inflammatory responses, thus alleviating discomfort caused by skin inflammation. However, high-molecular-weight hyaluronic acid is degraded by hyaluronidase, resulting in a decrease in its content and the production of the degradation product N-acetylglucosamine. Therefore, measuring the N-acetylglucosamine content in the reaction system can indirectly reflect the activity of hyaluronidase.

[0034] This embodiment determines the inhibition rate of hyaluronidase by measuring the N-acetylglucosamine content in the reaction system, thereby evaluating the soothing and repairing efficacy of the compositions.

[0035] Test samples: The compositions prepared in Examples 1-3 and Comparative Examples 1-7 were respectively added to an acetate-sodium acetate buffer solution with pH=5.6, mixed evenly, and prepared into a test solution with a concentration of 1.5 v / v%. The specific testing method is as follows: Take four clean test tubes and label them A, B, C, and D respectively. Test tube A is the sample group, test tube B is the sample control group, test tube C is the negative control group, and test tube D is the reagent blank group. Add 50 μL of the sample to be tested to each of test tubes A and B. Add 50 μL of acetate-sodium acetate buffer solution with pH=5.6 to each of test tubes C and D. Add 50 μL of 500 U / mL hyaluronidase solution (prepared with acetate-sodium acetate buffer solution with pH=5.6 as solvent) to each of test tubes A and C. Add 50 μL of acetate-sodium acetate buffer solution with pH=5.6 to each of test tubes B and D. Place the test tubes in a 37℃ incubator for 20 min. Add 10 μL of 2.5 mol / L CaCl2 solution to each of the four test tubes, and then incubate at 37℃ for 20 min. Add 50 μL of 0.5 mg / mL sodium hyaluronate solution (prepared with an acetate-sodium acetate buffer solution at pH 5.6) to test tubes A and C, and add 50 μL of an acetate-sodium acetate buffer solution at pH 5.6 to test tubes B and D. Incubate the test tubes at 37℃ for 40 min, and then let them stand at room temperature for 10 min. Add 50 μL of distilled water, 10 μL of 5 mol / L NaOH solution, and 50 μL of acetylacetone solution to each of the four test tubes, respectively. Place the test tubes in a boiling water bath for 30 min, then in an ice bath for 10 min, and finally let them stand at room temperature for 10 min. Add 100 μL of P-DAB reagent to each test tube, and then measure the absorbance at 530 nm using an ELISA reader. Each group was measured in parallel 3 times. The hyaluronidase inhibition rate was calculated according to the following formula. The data are presented as average values. The calculated data are shown in Table 2 below. ; In the formula: A represents the OD value of the sample group (test tube A); B represents the OD value of the sample control group (tube B). C represents the OD value of the negative control group (C tube); D represents the OD value of the reagent blank group (D test tube); Table 2 Hyaluronidase inhibition rate data Group Hyaluronidase inhibition rate (%) Example 1 85.23 Example 2 86.14 Example 3 88.79 Comparative Example 1 55.07 Comparative Example 2 67.41 Comparative Example 3 59.68 Comparative Example 4 62.80 Comparative Example 5 79.12 Comparative Example 6 74.25 Comparative Example 7 77.46 Example 2 of efficacy test: Inflammatory factor inhibition test TNF-α is the most common inflammatory factor in the inflammatory response. It can induce the phenotype of vascular endothelial cells to become inflammatory, leading to changes in the body's metabolism and hemodynamics, and promoting the production of inflammatory mediators. In turn, inflammatory mediators can increase vascular permeability, resulting in local congestion and edema, and may also stimulate nerve endings, causing skin itching and pain. Therefore, inhibiting TNF-α helps to soothe and repair the skin.

[0036] This efficacy test example evaluates the soothing ability of the compositions by detecting the inhibition rate of TNF-α of the compositions prepared in Examples 1-3 and Comparative Examples 1-7 of this application.

[0037] Sample preparation: The compositions prepared in Examples 1-3 and Comparative Examples 1-7 were diluted with DMEM medium to a concentration of 10 v / v% for the test solution. RAW264.7 cells grown to the logarithmic growth phase were fed with a 1.5 × 10⁻⁶ ppm. 5Cells were seeded at a density of 800 μL / mL in 24-well plates and incubated at 37°C in a 5% CO2 incubator for 24 h. When the cells reached near confluence, 50 μL of the test solution was added to each well of the sample group, 50 μL of 10 μg / mL dexamethasone was added to each well of the positive control group, and 50 μL of DMEM medium was added to each well of the blank control group. Each group had 3 replicates. After 1 h, the cells were stimulated with 1 μg / mL lipopolysaccharide (LPS) and incubated in a cell culture incubator for 24 h. The cell culture medium was then transferred to centrifuge tubes and centrifuged at 5000 rpm for 10 min to collect the cell supernatant. The cells were then detected according to the instructions of the mouse TNF-α enzyme-linked immunosorbent assay kit. The TNF-α inhibition rate is calculated as follows: ; In the formula: X 空白对照组 The TNF-α content of the blank control group; X 阳性对照组 The TNF-α content in the positive control group; X 样品组 The TNF-α content of the sample group is shown; each group was measured in triplicate, and the data are presented as the average value. The calculated data are shown in Table 3 below; Table 3 TNF-α inhibition rate data Group TNF-α inhibition rate (%) Blank control group 0.00 Example 1 82.79 Example 2 81.25 Example 3 84.63 Comparative Example 1 54.91 Comparative Example 2 67.32 Comparative Example 3 58.60 Comparative Example 4 64.57 Comparative Example 5 73.26 Comparative Example 6 77.08 Comparative Example 7 75.64 Compared with Example 3, Comparative Examples 1-4 did not contain one of the following: Stephania tetrandra extract, Date palmatum fruit extract, Sophora flavescens flower extract, and Mirabilis jalapa extract. Comparative Examples 5-7 had mass ratios of Stephania tetrandra extract, Date palmatum fruit extract, Sophora flavescens flower extract, and Mirabilis jalapa extract that were not within the range specified in this invention.

[0038] As shown in Tables 2-3, the data on hyaluronidase inhibition rate and TNF-α inhibition rate of Example 3 and Comparative Examples 1-4 indicate that Example 3, which uses a combination of four components—Stephania tetrandra extract, jujube fruit extract, Sophora flavescens flower extract, and Mirabilis jalapa extract—has a high hyaluronidase inhibition rate and TNF-α inhibition rate. This suggests that the four components have a synergistic effect, which improves the soothing and repairing effect of the composition.

[0039] Based on the data from Examples 1-3 and Comparative Examples 5-7 in Tables 2-3, it can be seen that when the mass ratio of Stephania tetrandra extract, Date palm fruit extract, Sophora flavescens flower extract, and Mirabilis jalapa extract is (2-10):(0.5-2):(1-5):(2-6), the composition has a better soothing and repairing effect. Furthermore, when the mass ratio of Stephania tetrandra extract, Date palm fruit extract, Sophora flavescens flower extract, and Mirabilis jalapa extract is 5:1:3:3.5, the composition has the best effect.

[0040] Application example: A serum with soothing and repairing effects The soothing and repairing compositions prepared in Examples 1-3 were added to the serums to obtain the serums used in Examples 1-3.

[0041] The soothing and repairing essence comprises the following components by weight percentage: 4% of the soothing and repairing composition, 0.1% carbomer, 0.15% xanthan gum, 3% trehalose, 5% glycerin, 2.5% lecithin, 0.7% potassium sorbate, 0.2% arginine, and the balance being deionized water.

[0042] The preparation method of the serum with soothing and repairing effects specifically includes the following steps: S1. Mix trehalose, glycerol, carbomer, xanthan gum and some deionized water, homogenize at 70°C, add lecithin at 85°C, and stir until homogeneous to obtain mixture I. S2. When the temperature of mixture I prepared in S1 drops to 60°C, potassium sorbate is added and stirred evenly. When the system temperature drops to 35°C, each component in the composition and the remaining deionized water are added and homogenized. Finally, arginine is added to adjust the pH to obtain the essence.

[0043] Blank application example: Compared with application examples 1-3, the difference is that the essence of the blank application example does not contain the soothing and repairing composition, and uses an equal amount of deionized water instead of the soothing and repairing composition. The preparation method is the same as that of application examples 1-3.

[0044] Example 3 of efficacy test: Human skin patch test This efficacy test case evaluates the safety of the serums prepared corresponding to test cases 1-3 and the blank application case, testing the potential for the test samples to cause adverse reactions on human skin. The test follows the relevant requirements and test methods for "Human Skin Patch Test" as shown in the "Cosmetic Safety Technical Specifications" (2015 edition). Test samples: serums prepared in Application Examples 1-3 and blank application examples; The specific experimental steps are as follows: Forty volunteers, half male and half female, aged 20-35 years, without inflammatory skin diseases or highly sensitive constitutions, were selected and randomly divided into four groups of 10 each. The skin of the flexor surface of the forearm, the test site, was cleaned and kept dry. 0.025 mL of the test sample was weighed and placed in the small chamber of the plaque applicator. The control well was a blank control (without any substance). The plaque applicator containing the test sample was applied to the flexor surface of the volunteer's forearm with hypoallergenic adhesive tape, and the palm was gently pressed to ensure even application to the skin for 24 hours. Skin reactions were observed at 30 minutes (after the pressure marks disappeared), 6 hours, 12 hours, 24 hours, and 48 hours after the plaque applicator was removed, and the results were recorded according to the standards in Table 4.

[0045] Table 4. Grading Criteria for Skin Reaction in Occlusive Patch Tests

[0046] Human skin patch test results showed that all volunteers had negative results and no adverse skin reactions, indicating that the essence prepared using the composition of the present invention will not cause allergic reactions, is non-irritating, and has high safety.

[0047] Example 4 of efficacy test: Human efficacy trial This test case evaluates the soothing and repairing effects of the serum in application cases 1-3 and the blank application case.

[0048] The specific experimental steps are as follows: Twenty-four volunteers with sensitive skin and skin barrier damage (TEWL ≥ 20 g / hm2) were recruited. On the day of their visit, no products were applied to the test area (face). After washing their faces, the volunteers sat quietly for 20 minutes in an air-conditioned room with a temperature of 21±1℃ and a humidity of 50±10%. They were then randomly divided into four groups of six. The TewaMeter transdermal moisture loss probe was used to test the transdermal moisture loss. ® Hex (Courage+Khazaka) and the Colorimeter CL400 color probe measured the initial TEWL and initial a* values ​​of each volunteer's left and right sides of the face, and the average value was taken. Each group of volunteers applied 0.5 mL of serum to their face twice a day, morning and evening. On day 28, the post-treatment TEWL and post-treatment a* values ​​of the facial skin were measured again, and the average value was taken. The improvement rate (%) was calculated using the following formula:

[0049] In the formula: The initial TEWL value is the TEWL value before using the serum; The TEWL value after use was the TEWL value on day 28 of using the serum;

[0050] In the formula: The initial a* value is the a* value before using the serum; The a* value after use is the a* value on the 28th day after using the serum; Among them, the higher the TEWL value improvement rate, the stronger the skin barrier damage repair ability of the serum; the higher the a* value improvement rate, the stronger the soothing and redness-reducing ability of the serum. The specific results are shown in Table 5. Compared with the blank application example, the improvement rates of TEWL value and a* value of application examples 1-3 were significantly improved, indicating that the essence prepared by the composition provided by the technical solution of the present invention can significantly improve the soothing and repairing effect, and can significantly improve the skin's barrier function and moisture retention ability, and has the ability to soothe and reduce redness.

[0051] Table 5. Human Trial Evaluation Data Group TEWL value improvement rate (%) a* value improvement rate (%) Blank application example 3.89 4.51 Application Example 1 22.46 15.83 Application Example 2 23.18 14.97 Application Example 3 25.34 18.65 The above description is merely a preferred composition of the present invention and is not intended to limit the present invention in any way. Although the present invention has been disclosed above with preferred compositions, it is not intended to limit the present invention. Any person skilled in the art can make some modifications or alterations to the above-disclosed technical content to create equivalent compositions without departing from the scope of the present invention. Any simple modifications, equivalent changes and alterations made to the above compositions based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the scope of the present invention.

Claims

1. A soothing and repairing composition, characterized in that, By weight percentage, it comprises the following components: 2%-10% Stephania tetrandra extract, 0.5%-2% Date palm fruit extract, 1%-5% Sophora flavescens flower extract, 2%-6% Mirabilis jalapa extract, 25%-35% Butylene glycol, 1.5%-3.5% 1,2-pentanediol, 1%-3% 1,2-hexanediol, with the balance being deionized water.

2. The soothing and repairing composition as described in claim 1, characterized in that, By weight percentage, it comprises the following components: 5% Stephania tetrandra extract, 1% Date palm fruit extract, 3% Sophora flavescens flower extract, 3.5% Mirabilis jalapa extract, 30% Butylene glycol, 3% 1,2-pentanediol, 2% 1,2-hexanediol, with the balance being deionized water.

3. A method for preparing the soothing and repairing composition according to claim 1 or 2, characterized in that, The process includes the following steps: weigh each component according to the formula amount, mix the extracts of Stephania tetrandra, jujube fruit extract, senna flower extract, Mirabilis jalapa extract and deionized water evenly, add butylene glycol, 1,2-pentanediol and 1,2-hexanediol, mix evenly to obtain the soothing and repairing composition.

4. The use of the soothing and repairing composition according to claim 1 or 2 in the preparation of cosmetics, skin care products or washing and care products having soothing and repairing effects.

5. The composition according to claim 4, characterized in that, The cosmetic product is in the form of an aqueous solution, emulsion, or cream.

6. The composition according to claim 4, characterized in that, The dosage form of the skin care products is cream, lotion, water, gel, or mask.

7. The composition according to claim 4, characterized in that, The dosage form of the washing and care products is water, lotion, or cream.

8. The composition according to claim 4, characterized in that, The cosmetic product is any one of the following: sunscreen, makeup base, primer, foundation, setting powder, concealer, contouring powder, or blush.

9. The composition according to claim 4, characterized in that, The skincare product is any one of toner, lotion, cream, mask, or freeze-dried powder.

10. The composition according to claim 4, characterized in that, The hair care product is any one of shampoo, hair mask, or shower gel.

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