The invention relates to the field of automobile manufacturing, in particular to high-precision positioning, clamping and polishing equipment for multiple types of hubs. The equipment comprises a machine frame, a positioning and clamping mechanism, a polishing mechanism and a rotary driving mechanism. A working platform is horizontally arranged on the machine frame, a mounting frame is arranged atthe top of the machine frame, the mounting frame is positioned over the working platform, the positioning and clamping mechanism is installed inside the machine frame and positioned below the workingplatform, the rotary driving mechanism is installed at the top of the mounting frame, the polishing mechanism is arranged at the output end of the rotary driving mechanism, and the polishing mechanism comprises a polishing head capable of polishing the outer edges of the hubs. The high-precision positioning, clamping and polishing equipment for the multiple types of hubs can machine different types of hubs, has automatic production capacity, greatly reduces labor intensity, can accurately and quickly polish the outer edges of the hubs, improves product quality, improves working efficiency, improves equipment applicability, and reduces production cost.