69 results about "Fungal pathogen" patented technology

Described are immunogenic compositions comprising a non-naturally occurring pan-fungal Kex peptide, and methods of using such compositions for the treatment or prevention of infection and / or diseases associated with fungal pathogens (e.g., Pneumocystis, Aspergillus, Candida, or Cryptococcus) in the subject. Also provided are compositions and kits for detecting or quantifying the presence of antibodies directed against a non-naturally occurring pan-fungal Kex peptide in a subject.

The disclosure relates to methods and compositions for altering the production of one or more secondary plant metabolites comprising applying an effective amount of at least one elicitor, wherein the elicitor is a jasmonate or a salicylate, and combinations thereof. The disclosure further teaches compositions comprising effective amounts of the elicitors disclosed here. The disclosure further relates to methods and compositions for controlling plant pathogens, such as fungal pathogens.

The present invention is directed to stable flumetylsulforim compositions, combinations of fluxapyroxad and rapeseed oil, and to a method for the control and / or prevention of (i) fungal pathogen attack on a plant or (ii) plant and / or soil fungal disease, wherein the method comprises applying the composition or the combination described herein.

This invention provides compounds and methods of application that possess both broad-spectrum antifungal activity and plant-induced resistance, belonging to the field of agricultural technology. It addresses the problem that "traditional pure immune inducers must be applied before disease onset, making it difficult to meet the full-cycle control needs of disease prevention and treatment in the field." Compared to the previously developed PC1 and PC20, the two compounds of this invention, 2,4-dibromo-6-nitrophenol and 7-deazon-2'-deoxy-7-iodoadenosine, can both inhibit the growth of rice blast fungus and significantly improve rice resistance to rice blast through foliar spraying, meeting the full-cycle control needs of disease prevention and treatment in the field. Furthermore, these two compounds can directly inhibit the growth of various fungal pathogens such as peanut white mold, tomato gray mold, wheat scab, rice bakanae disease, rice false smut, mango malformation, and banana wilt.

The present invention provides for an engineered, genetically modified, and / or synthetic plant receptor comprising a binding sequence that is capable of binding a fungal pathogen Avr ligand; wherein the non-engineered, genetically unmodified, and / or naturally occurring plant receptor does not bind the fungal pathogen Avr ligand, or bind with a lower binding affinity.

The present disclosure is directed to an approach using dsRNA to reduce or eliminate the production of DON by the fungal pathogen, F. graminearum or other fungal pathogens of the genus Fusarium and / or to control F. graminearum or other fungal pathogens of the genus Fusarium. In particular embodiments, methods and compositions are described to provide control of DON production and / or to control the fungal pathogen by causing mortality, suppression of growth, decrease in virulence or pathogenicity, or decrease in propagation / reproduction capacity (sporulation), by using exogenous dsRNA application administered to plants that are infected by or may become infected by F. graminearum or another member of the genus Fusarium that produces DON or otherwise is involved in Fusarium species complex that caused head blight.

This invention relates to the fields of microbiology and biotechnology, and discloses Bacillus coagulans PPX-13 and its applications. Strain PPX-13 is a thermotolerant, multifunctional phosphate-solubilizing biocontrol bacterium that can reduce rhizosphere soil acidification in tea trees, improve fertility, enhance the microbial ecological environment, improve the functional microbial community and structure, inhibit mold communities and structure, and increase the yield of spring tea. It has been identified as Bacillus coagulans. This bacterium exhibits mesophilic and thermotolerant phosphate-solubilizing activity; phytase activity; multiple enzyme activities; and mesophilic antagonistic activity against isolates of anthracnose fungal pathogens. This strain holds promise for development into a novel agricultural microbial agent, which is of great significance for mitigating soil acidification, reducing fertilizer use, activating soil nutrients, improving soil quality, and increasing plant (especially tea) yield and quality.

The application discloses a method for synthesizing an antifungal pathogen reagent N-methyl-3-[(4-methylphenyl)thio]quinolinium iodide by realizing quinoline C3-H heteroatomization under nickel catalysis and mild conditions. The method comprises two steps, first, 3-(p-tolylthio)quinoline is synthesized under room temperature conditions, and then quinoline is N-methylated, so as to prepare the antifungal pathogen reagent N-methyl-3-[(4-methylphenyl)thio]quinolinium iodide. Compared with the past reports, the starting material is more cheap and easy to obtain, the steps are more simple, the atom utilization rate is higher, and the conditions are more mild, so the method is more suitable for kilogram scale amplification production.

The present invention relates to a method of conferring or increasing resistance to a plant and / or plant material against a fungal pathogen. To this end, the invention focuses on promoting or increasing the production and / or accumulation of Membrane Steroid Binding Protein 1 (MSBP1), fragments or homologues thereof in a plant or plant material as compared to the corresponding wild type plant or plant material. The invention also relates to plants and plant materials having increased resistance to fungal pathogens, as well as materials and methods of producing or using such plants, plant parts or products therefrom.

Described herein are fungicidal compositions and methods of controlling and / or suppressing phytopathogenic fungi and fungus-like pathogens and maintaining crop health. Particularly described are fungicidal compositions and methods of controlling the phytopathogenic fungi and the Aphanomyces fungus-like pathogen and maintaining crop health in crops susceptible to infection.

A system and methods for gas infusion tailored for manufacturing, prevention, and the application of fungicides in agriculture and aquaculture includes a microporous hollow fiber gas infusion module, engineered to efficiently dissolve gases such as oxygen or ozone into aqueous streams, thereby revolutionizing disease prevention and treatment strategies. Complementing the gas infusion module is a suite of manufacturing equipment and methodologies tailored for the production of oxygen-infused or other nutrient gas-infused products, catering to the diverse needs of agricultural and aquacultural industries. The system and method addresses the pervasive challenges posed by fungal pathogens in agriculture, such as Botrytis cinerea, Sclerotinia sclerotiorum, Pythium spp., and in aquaculture, particularly Saprolegnia, by offering comprehensive solutions encompassing precise gas infusion techniques, innovative disease prevention strategies, and sustainable manufacturing processes to enhance crop yields, promote environmental sustainability, and ensure the long-term viability of agricultural and aquacultural sectors.

A Capsicum plant resistant to powdery mildew caused by the fungal pathogen Leveillula taurica, a cell, plant part or seed of the Capsicum plant and to methods for identifying it, and the use of the plants for improving the yield of pepper production in an environment infected by Leveillula taurica and / or for limiting or controlling an infection by Leveillula taurica; wherein, the Capsicum plant includes introgressed in its genome a quantitative trait locus (QTL) conferring resistance to powdery mildew, wherein the QTL is located on chromosome 6 within the genomic interval delimited by the marker PE-0014628 (SEQ ID NO: 1) and the marker PE-0021476 (SEQ ID NO: 37).

TITLE: USE OF A BACILLUS SIAMENSIS STRAIN AS A BIOSOLUTION IN MUSHROOM CULTIVATION The present invention relates to the use of a particular bacterial species as a biosolution in the production and cultivation of mushrooms. More specifically, the invention relates to the use of a Bacillus siamensis strain, registered with the CNCM under CNCM order number I-5921, in stimulating the development and growth of a mycelium or fungus, improving the yields of edible mushroom crops, and controlling the main fungal pathogens of edible mushroom crops. [Fig. 1]

The present invention relates to a method of conferring or increasing resistance against fungal pathogens in plants, plant parts, and / or plant cells. To this end the invention focuses on facilitating or increasing the production and / or accumulation of a Myb41-type transcription factor (Myb41), fragment or homolog thereof in a plant, plant part and / or plant cell compared to corresponding wild type plants, wild type plant parts and / or wild type plant cells. The invention also relates to plants, plant parts, and / or plant cells having an increased resistance against fungal pathogens and to material and methods to create or use such plants plant parts or to produce products therefrom.

Disclosed are compounds of Formula 1, including all geometric and stereoisomers, tautomers, N-oxides, and salts thereof,whereinR1, L and J are as defined in the disclosure.Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.

An antifungal compound / conjugate is derived from quercetin, a naturally occurring flavonoid, through a strategic conjugation approach. The resulting quercetin conjugate exhibits enhanced antifungal activity and improved pharmacological properties compared to its parent molecule. The conjugate demonstrates potent efficacy against a range of drug-resistant fungal pathogens, including Candida auris, a critical threat in clinical settings due to its multidrug resistance. The invention also encompasses methods for synthesizing the conjugate, formulating the conjugate in a pharmaceutical preparation, and methods of use for treatment and prevention of superficial and systemic fungal infections.

The present disclosure provides compositions and methods for making transgenic plants expressing a resistant Lr34 protein that exhibit increased resistance to fungal diseases, and transgenic plants produced by these methods, and plant parts thereof. The present disclosure provides transgenic plants, and plant parts thereof, that are resistant or immune, or have reduced susceptibility, to Asian Soybean Rust (ASR) and other fungal pathogens, while demonstrating minimized or reduced undesirable off-types. The present disclosure provides effective transgenic expression of Lr34 in soybean varieties to reduce the need for one or more fungicide applications, and / or protecting against fungal pathogens developing resistance to both the chemical control agents and other native or engineered disease resistance genes.

The present application provides a new technology to confer or enhance insect resistance and, optionally also resistance to fungal pathogens in plants. In particular, the present invention provides a method for conferring or increasing resistance or tolerance to insect and optionally also to fungal pathogens in maize and oil seed rape (OSR) by targeting the endogenous Lox3 gene. Further provided are resistant or tolerant maize or oil seed rape plants, cells, tissues, organs or seeds, which are obtained or obtainable by the method according to the present invention. Expression constructs and vectors for the different approaches described herein are also provided as well as the use of such constructs and methods to confer or increase insect and optionally fungal resistance in plants.

Systems and methods for identification of fungal pathogens, including Candida auris and other Candida species, using Raman spectroscopy integrated with machine learning are described. The systems and methods can utilize a counter-propagating Gaussian beam Raman spectroscopy (CPGB-RS) system in combination with a Convolutional Neural Network (CNN) that processes the Raman spectral data to identify and classify fungal species with high accuracy, sensitivity, and specificity.

The application discloses a salt-tolerant Bacillus G3-2 antagonizing multiple fungal pathogens and an application thereof. The salt-tolerant Bacillus G3-2 is preserved in the China General Microbiological Culture Collection Center on November 27, 2025, and has a preservation number of CGMCC No. 36791. The salt-tolerant Bacillus G3-2 has an inhibiting effect on multiple plant pathogenic fungi, solves the problem of a narrow inhibiting range of a biocontrol strain, and meets the comprehensive prevention and control requirements of multiple crop diseases including apple rot disease, apple leaf spot disease, apple replant disease, banana wilt disease and the like. In addition, it is found that a fermentation liquor of the strain can promote the growth of corn seedlings, including increasing plant height, maximum root length and underground fresh weight, total root length, root diameter, root surface area, root projection area and root tip number of the seedlings. In summary, the strain has dual functions of growth promotion and biological control, and has a good application prospect.

This invention provides a method for inhibiting the growth of a pathogenic mold by contacting the pathogenic mold with a synergistically effective amount of an NK1 antagonisfand an antifungal agent. This invention also provides a method for inhibiting the growth of a mammalian fungal pathogen by contacting the mammalian fungal pathogen with a synergistically effective amount of posaconazole and rolapitant. In some aspects, the mammalian fungal pathogen is a species of Candida (e.g., C. glabrata, C. auris, C. albicans, C. dubliniensis, or C. parapsilosis). Aspergillus, Cryptococcus, Mucor, orRhizopus. In addition, A surface disinfectant comprising a synergistic amount of an NK1 antagonist and an antifungal agent in admixture with a carrier or excipient.

The invention discloses a kit for efficiently capturing fungal pathogen nucleic acid from soil as well as a preparation method and application of the kit. The preparation method comprises the following steps: the kit comprises a solid culture medium enrichment bar, a rapid lysis solution and a neutralization solution. After the enrichment bar is inserted into the soil to be detected, the pathogenic bacteria are enriched on the culture medium matrix of the enrichment bar by utilizing the isotropic growth of the pathogenic bacteria, and the target pathogenic bacteria are physically purified from the soil environment rich in inhibitors. According to the method, nucleic acid purification is not needed, rapid alkali lysis can be directly carried out on the enriched product, and the obtained nucleic acid lysis solution can be directly used as a detection template for high-sensitivity molecular detection. According to the method, the problem of interference of the soil inhibitor on molecular detection is fundamentally solved, high-difficulty soil nucleic acid extraction is simplified into high-efficiency rapid nucleic acid extraction, and a key solution is provided for field on-site detection.

This invention discloses a strain of *Streptomyces bovis* M11 and its application in the control of plant diseases. The strain screened in this invention... Streptomyces tauricus M11 is deposited at the China Center for Type Culture Collection (CCTCC), accession number CCTCC NO: M 20252441. The *Streptomyces bovis* M11 screened in this invention exhibits strong inhibitory effects against various filamentous fungal pathogens, particularly showing significant efficacy in controlling the newly discovered blueberry pathogen *Cladosporium filamentum*. M11 possesses excellent biocontrol capabilities and shows promising application prospects as a biocontrol agent for plant diseases, especially providing an effective biocontrol agent for diseases caused by the newly discovered blueberry pathogen *Cladosporium filamentum*.

The invention relates to the technical field of microbial pesticides, in particular to a complex microbial inoculant for preventing and treating garlic diseases and a preparation method and application thereof.The complex microbial inoculant is composed of seven strains including bacteria and fungi T4, JR14, BR55, A25, BR33, BR43 and JR22, experiments prove that the complex microbial inoculant has excellent garlic pathogenic bacterium hypha inhibition and sporulation inhibition effects, and the complex microbial inoculant can be used for preventing and treating garlic diseases. All bacterial and fungal candidate strains participate in inhibition of fungal pathogens through synergistic interaction. The potting effect verifies that the growth of garlic plants is severely influenced under the stress of T9 pathogenic bacteria, but the complex microbial inoculant disclosed by the invention not only can keep the normal growth of the garlic plants and has no obvious difference with the plant height of the plants growing in normal soil, but also has a certain effect of promoting the growth of the garlic plants.

The present application presents peptides that binds selectively to fungi, in particular opportunistic fungi, and not to human cells. These properties can be utilized to specifically target invading fungal pathogens, and via genetic engineering create peptibodies. Thus, the present application describes novel approaches for detection and treatment of infections caused by fungi.

Disclosed herein are biocontrol compositions against plant fungal pathogens and methods of use thereof for the prevention or reduction of crop loss or food spoilage. The biocontrol composition may comprise at least one microbe, or a secondary metabolite of the at least one microbe, with anti-fungal or anti-pathogenic activity. The methods and compositions disclosed herein may prevent or inhibit the growth of a variety of different pathogens, including pathogens of the genus Penicillium. The biocontrol compositions may be applied to a plant, a seed, or a produce thereof or to a packaging material used to transport or store the produce.

The present invention provides a method treating specified crop (A) or a locus thereof against fungal pathogen (I) infection comprising applying an amount of a phthalimide fungicide to the crop or locus so as to thereby treat the crop or locus against the fungal pathogen infection. The present invention also provides crop-safe methods and compositions for treating fungal pathogen infection in crops (A).

This invention belongs to the field of microbial control technology and provides a *Pseudomonas aeruginosa* strain JHMC Fb2317 and its application in controlling cowpea anthracnose (CCTCC NO: M 20251695). This invention involves targeted screening of functional bacteria from cowpea rhizosphere soil. Using the plate confrontation method, the most effective antagonistic bacterium against cowpea anthracnose, JHMC Fb2317, was ultimately selected, exhibiting an inhibition rate of 90.0%. Its broad-spectrum antibacterial activity indicates that this strain has varying degrees of inhibitory effects against 10 fungal pathogens, including *F. anthracnose*, *F. wilt*, *F. sclerotinia*, and *F. wilt*. Field trial results show that, compared to the control group, application of JHMC Fb2317 significantly reduced the cowpea disease index and increased cowpea yield, providing technical support for green control of legume diseases.

This disclosure relates to a method for controlling plant pathogens, including fungal pathogens. In particular, this disclosure provides a method for controlling fungal infection in soybean crops by applying a fungicide. This disclosure also relates to its appropriate uses.