Patents
Literature
4 results about "Transfer DNA" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
The transfer DNA (abbreviated T-DNA) is the transferred DNA of the tumor-inducing (Ti) plasmid of some species of bacteria such as Agrobacterium tumefaciens and Agrobacterium rhizogenes(actually an Ri plasmid). The T-DNA is transferred from bacterium into the host plant's nuclear DNA genome. The capability of this specialized tumor-inducing (Ti) plasmid is attributed to two essential regions required for DNA transfer to the host cell. As the T-DNA is bordered by 25-base-pair repeats on each end. Transfer is initiated at the right border and terminated at the left border and requires the vir genes of the Ti plasmid.
Targeted modification of genomes using single stranded circular DNA
The present invention relates to methods of generating one or more transgenic cells using circular single stranded DNA (CiSSD) as a donor template, as well as target genome modification. The methods include transferring one or more DNA polynucleotides into a cell for site-specific nuclease-mediated DNA repair, and selecting one or more cells into which the transferred DNA is introduced in the genome of the cell.
Owner:FUSHENGYUAN CO LTD
Methods for maintaining methylation in amplification of methylated nucleic acid molecules
The present disclosure provides methods for preparing preparations of DNA from a subject useful for determining a methylation status of a genomic region of interest. The methods comprise extracting DNA from a sample of a subject; copying one or more template DNA molecules from the extracted DNA to generate one or more copied DNA molecules; transferring methylation status from the one or more template DNA molecules to the one or more copied DNA molecules, thereby generating one or more methylation-transferred DNA molecules; and repeating the copying and transfer steps to generate a library of amplified DNA molecules comprising the one or more methylation-transferred DNA molecules. The method may employ isothermal extension at 60°C and strand-invasion or linked primers.
Owner:NATERA INC +1
Targeted genome modification using circular single-stranded DNA
PendingUS20260146261A1Organic active ingredientsImmunoglobulin superfamilySingle strandGene Modification
The present invention is directed to methods for generating one or more genetically modified cells by using a circular single stranded DNA (CiSSD) as a donor template and targeting genome modification. These methods include transferring one or more DNA polynucleotides into the cell for site-specific nuclease-mediated DNA repair and selecting one or more cells having the transferred DNA incorporated into the cell's genome.
Owner:FULL CIRCLES THERAPEUTICS