32 results about "Droplet flow" patented technology

The invention belongs to the technical field of microfluidics, and particularly relates to a microfluidic chip and a method for preparing liquid drops in a high-flux and large-scale manner. A step emulsification structure and a liquid drop splitting structure are used together, a liquid drop generation structure is arranged at the communication position of a branch splitting channel and a main channel unit correspondingly communicated with the branch splitting channel, a dispersion phase necks at the liquid drop generation structure under the action of interfacial tension to form liquid drops, and the liquid drops are generated under the leading of the interfacial tension, so that the dispersion phase is uniform in dispersion. Therefore, the size of the liquid drops is basically determined by the channel width of the liquid drop generation structure, the branch splitting channel is designed to be wide, the influence of manufacturing errors on the uniformity of the generated liquid drops can be reduced, the branch splitting channel is designed to be a plurality of serpentine channels, and the uniformity of the liquid drops is improved while high-flux liquid drop preparation is guaranteed; and then the liquid drops flow through the main channel unit and are converged into the main splitting channel, and the liquid drops are uniformly split into liquid drops with smaller sizes through the liquid drop splitting structure, so that the preparation of the liquid drops with high flux and uniform sizes is realized.

The invention discloses a method for microfluidic high-throughput screening of AKK bacteria. The method comprises the following steps: 1) preparing a microfluidic chip; 2) collecting fresh excrement of healthy volunteers, diluting, and adding a fluorescence labeled antibody to obtain a dispersion phase; and (3) preparing liquid drops by taking paraffin oil and Span-80 as a mobile phase, enabling the liquid drops to enter a liquid drop culture tank through an S-shaped liquid drop circulation channel, culturing, introducing the mobile phase, introducing the liquid drops in the liquid drop culture tank into a liquid drop collection tank, taking out, detecting a fluorescence signal, culturing the liquid drops with the fluorescence signal on the improved brain heart infusion broth solid culture medium, and obtaining the brain heart infusion broth. Obtaining a to-be-identified strain; 4, the strain to be identified serves as a template, PCR amplification is conducted, sequencing is conducted on an amplification product, BLAST sequence comparison is conducted on a sequencing result on an NCBI website, and the target strain AKK bacterium is screened out. The method has the advantages of being high in throughput, simple in experimental process and high in specificity, and the screening efficiency of the AKK bacterium can be improved.

The application discloses a microfluidic droplet generation control method, device, equipment and medium, relates to the field of microfluidic droplet generation, and comprises the following steps: first, dividing nodes and judging the flow state of each node according to a limited parameter by using a flow state classifier; predicting the droplet diameter by using a stacking integrated size regression model based on an ideal droplet flow state node; screening candidate nodes based on an accuracy tolerance constraint; determining local sensitivity based on a virtual flow rate micro-perturbation and a flow state boundary risk penalty; determining a robust candidate solution set based on a comprehensive risk score according to the local sensitivity and a confidence interval width; extracting a cluster and a representative solution for each candidate node in the robust candidate solution set; and calculating the two-phase flow control parameters for the representative solution of each cluster in the dimension of the continuous phase flow rate and the dispersed phase flow rate by using a univariate step-by-step double-criterion termination algorithm based on a cascade model, so that the time cost and the material cost are reduced.

This invention discloses a piezoelectric valve nozzle cleaning management method and system based on identifier traceability, specifically relating to the field of piezoelectric jet equipment operation and maintenance technology. The method involves reading the unique identifier of the piezoelectric valve nozzle to trace individualized cleaning records; dynamically generating customized cleaning strategies based on the records, determining the solvent type and piezoelectric excitation waveform parameters; first, driving a small atomizing valve to generate an atomized cloud for non-destructive pre-wetting of the nozzle surface, then driving the piezoelectric valve for active excitation cleaning; driving the small atomizing valve to generate standardized droplet flow as a probe, capturing the characteristic spectrum after passing through the nozzle area through a detection unit and comparing it with a standard spectrum to quantitatively evaluate the cleaning effect and accurately locate the blocked nozzle; updating the records based on the detection results, and if the cleaning is unqualified, optimizing the strategy based on the blockage location information and iteratively executing it until qualified.

The application discloses a non-contact flow field measuring device and method with nitrogen droplets as tracer particles, and belongs to the technical field of flow field visualization. A Laval nozzle is used as a nitrogen droplet generating device, and the Laval nozzle is arranged in a high-speed flow section. After the nitrogen droplets flowing out of the Laval nozzle are mixed with the main flow in the high-speed flow section, the nitrogen droplets pass through an expansion section and a flow regulation section and then enter a speed measuring section. A high-speed camera is used in the speed measuring section to capture the nitrogen droplets and obtain the air flow speed. By actively regulating and controlling the operating parameters of the wind tunnel, the total temperature, the Ma number and the expansion ratio of the Laval nozzle in the wind tunnel are reasonably controlled, so that the condensation nitrogen droplets are spontaneously generated at a proper position, the condensation degree is controlled, and the disturbance of the flow field near the test model is reduced as much as possible. The application aims to solve the key problem that suitable and available tracer particles are lacked in the application of the non-contact measurement technology in a low-temperature wind tunnel, and provides a new feasible way for the application of the non-contact flow field measurement technology in a transonic low-temperature wind tunnel.

The application relates to a device and a method for realizing particle aggregation in a droplet, which comprises: a microfluid channel for providing a channel for droplet flow; a first bulk acoustic resonator close to the microfluid channel, the working range of the first bulk acoustic resonator including the space in the microfluid channel; the overall shape of the first bulk acoustic resonator is arranged to be narrowed from the front end to the tail end, and the tail end is an outwardly convex arc-shaped end portion, the arc-shaped end portion being used for making particles in the droplet be aggregated at a first position in the droplet during the process that the droplet flows through the first bulk acoustic resonator; and the tail end is located on the downstream side in the microfluid channel relative to the front end. The scheme of the application can realize that particles in the droplet are aggregated at a first position in the droplet, so as to facilitate observation or the interaction of different particles in the droplet after aggregation.

To accurately detect fine particles without complicating a device configuration.SOLUTION: The condensation particle counter includes a supply unit configured to supply a working fluid to a periphery of an inlet of a condensation tube through which an aerosol containing sample particles flows, a saturation unit configured to saturate the aerosol with vapor of the working fluid, and a control unit configured to condense and grow the aerosol into droplets using the sample particles as nuclei and extract the aerosol containing the droplets from a center axis of a condensation-growth tube connected to the condensation tube. A condensation and growth section that and exhausts excess working fluid that has flowed down an inner wall of a condensation and growth tube, vapor of the working fluid that has condensed on the inner wall, and water vapor together with excess aerosol, a flow rate control section that controls a flow rate of the aerosol flowing through a capillary tube that the aerosol containing droplets after condensation and growth at a minute flow rate, a double cylindrical sheath flow that positions the aerosol that has passed through the capillary tube on an extension line of a central axis of the capillary tube, and a droplet counting section that counts the droplets contained in the aerosol based on the droplets flowing through the capillary tube, wherein the working fluid contains an alkane having a carbon number of 14 or less.SELECTED DRAWING: Figure 1

A miniaturized, automated method for controlled printing of large arrays of nano- to femtoliter droplets by actively transporting mother droplets over hydrophilic-in-hydrophobic (“HIH”) micropatches. The technology uses single or double-plate devices where mother droplets can be actuated and HIH micropatches on one or both plates of the device where the droplets are printed. Due to the selective wettability of the hydrophilic micropatches in a hydrophobic matrix, large nano- to femtoliter droplet arrays are created when mother droplets are transported over the arrays. The parent droplets are moved by various droplet actuation principles. Also, a method using two plates placed one top another while being separated by a spacer. One plate is dedicated to confirming and guiding parent droplets by using hydrophilic patches in a hydrophobic matrix, while the other plate contains HIH arrays for printing of the droplets. When the parent droplet guidance plate is rotated over the plate dedicated to printing of nano- to femtoliter droplets, the droplets are dispensed inside the HIH array utilizing their selective wettability. The methods allow the parent droplets to move over the HIH arrays many times, providing advantages for performing bio-assays or miniaturized materials synthesis in nano- to femtoliter sized droplets. With controlled evaporation of the dispensed droplets of solution, large arrays of printed material can be generated in seconds. The methods provide a nano- to femtoliter droplet printing technique for a wide variety of applications, e.g., protein- or cell-based bio-assays or printing of crystalline structures, suspensions of nanoparticles or microelectronic components.

Systems and methods for initializing an extreme ultraviolet (EUV) source are discussed. The EUV radiation source may include a droplet generator configured to generate a stream of droplets of a target material, a laser source communicatively coupled to a controller. The laser source is configured to generate a first pulsed beam of light, which upon interaction with a droplet, initiates a modification of a shape of the droplet, forming a modified droplet, and generate a second pulsed beam of light configured to substantially evaporate the modified droplet, thereby generating pulses of EUV light. The EUV radiation source comprises a first actuator communicatively coupled to the controller and configured to adjust a width of the second pulsed beam to minimize a variation of energy of the pulses of EUV light.

In one embodiment, a system includes a flow cell with a conductive electrode and a base having an opening allowing variable charged sheathed sample fluid to flow out along a fluid axis, a droplet deflection unit with a pair of charge plates and a deflection chamber with a pivot door closing over the chamber a hardware triggered camera mounted to the back of the deflection chamber, and an LED array strobe light mounted to the pivotal door opposite the camera. The LED array strobe light generates a backlighting for various droplet streams. Triggering of the camera is synchronized with the generation of the backlighting to periodically capture a brightfield still image of deflected droplets and center droplets in the deflection chamber. The captured images can be analyzed for droplet deflection angles and center line for visual feedback control of the deflected droplets and the center droplets in respective droplet streams.

To provide a droplet deflector having an optimized deflection plate.SOLUTION: Droplet deflectors of interest include droplet deflectors comprising deflection plates configured for high angle deflection of a droplet flow stream. Droplet deflectors of interest further include those comprising deflection plates having a shape corresponding to the path of the deflected droplet flow stream, or deflection plates configured to apply a deflection force to the flow stream at a plurality of different angles. Droplet deflectors of interest further include droplet deflectors that are configured to apply a constant deflection force to the deflected droplet flow stream from a plurality of different lateral positions, e.g., wherein the deflector plate is a segmented deflector plate. Further provided are flow cytometers comprising the subject droplet deflectors, as well as methods of using and assembling or configuring the same.SELECTED DRAWING: None

An illumination source includes a droplet generator, a laser, a detector, and a controller. The droplet generator produces a stream of droplets of target material directed to an interaction region. The laser irradiates the droplets at the interaction region using a beam of pulses. The irradiated droplets generate output illumination of the illumination source. The detector measures an aspect of an interaction between a pulse from the beam and a droplet from the stream. Controller includes circuitry and determines a pulse timing adjustment that is nonlinearly dependent on the measured aspect. The controller also controls a subsequent laser pulse of the beam based on the pulse timing adjustment.

In one embodiment, a system includes a flow cell with a conductive electrode and a base having an opening allowing variable charged sheathed sample fluid to flow out along a fluid axis, a droplet deflection unit with a pair of charge plates and a deflection chamber with a pivot door closing over the chamber a hardware triggered camera mounted to the back of the deflection chamber, and an LED array strobe light mounted to the pivotal door opposite the camera. The LED array strobe light generates a backlighting for various droplet streams. Triggering of the camera is synchronized with the generation of the backlighting to periodically capture a brightfield still image of deflected droplets and center droplets in the deflection chamber. The captured images can be analyzed for droplet deflection angles and center line for visual feedback control of the deflected droplets and the center droplets in respective droplet streams.

The embodiment of the present application discloses a kind of microfluidic chip.The microfluidic chip includes oppositely arranged first substrate and second substrate, microfluidic channel is formed between first substrate and second substrate, microfluidic channel is used to accommodate at least one droplet;Multiple drive electrodes, multiple first sensing electrodes and multiple second sensing electrodes are located on the side of first substrate, adjacent drive electrodes are loaded with different drive voltage signals to drive droplet to move;First sensing electrode and second sensing electrode are loaded with detection signal, and the position of droplet is determined according to the change of the capacitance formed by first sensing electrode and a certain electrode and the change of the capacitance formed by second sensing electrode and a certain electrode when droplet flows.The microfluidic chip provided by the present application can obtain the position of droplet while driving the movement of droplet, and solve the problem of low reliability of equipment caused by the inability to detect the position of droplet in the prior art.

A method for accurately capturing droplet topological structure evolution in a drop flow falling film process belongs to the technical field of falling film evaporation research, combines computational fluid dynamics (CFD) software Fluent, and utilizes a user-defined equation to introduce a dynamic contact angle model into a mathematical model, so as to accurately capture the droplet topological structure evolution in the drop flow falling film process. The invention provides a method for accurately capturing the evolution of a liquid drop topological structure in a drop flow falling film process. According to the method, two-dimensional and three-dimensional falling film evaporation physical models are constructed, liquid drop topological structure evolution, film thickness distribution and speed and pressure distribution of liquid drops in the axial and circumferential spreading process of a horizontal pipe are analyzed, and causes of phenomena of circumferential spreading of liquid rings, liquid drop pulsation, axial shrinkage and the like of the liquid drops are clarified; according to the method, the flow mechanism of the drop flow falling film can be deeply understood, and an important theoretical basis and a numerical simulation means are provided for design and optimization of an efficient falling film evaporator.

The invention provides a bionic stomach micro-fluidic chip based on liquid drop micro-fluidic control and mechanical force stimulation and application of the bionic stomach micro-fluidic chip. The bionic stomach micro-fluidic chip comprises a liquid drop generation module and a mechanical force stimulation module. The liquid drop generation module is used for dispersing artificial stomach digestive juice and a to-be-digested Newtonian fluid sample in an oil phase by utilizing a micro-fluidic chip structure to form monodispersed water-in-oil liquid drops to simulate a discrete chyme group; and the mechanical force stimulation module is provided with a micro-channel with a periodically variable cross section. When liquid drops flow through the flow channel, the liquid drops are extruded and deformed periodically, a complex flow field is generated in the liquid drops, and the mechanical kneading effect of stomach wall wriggling on chyme balls is simulated. By limiting biochemical reaction in micro-droplets and applying controllable physical shear force, collaborative high-fidelity simulation of chemical and mechanical effects in the gastric digestion process is realized, and the problems that a traditional static model is low in simulation degree and large dynamic equipment is low in flux and high in cost are solved. And a brand new high-throughput research platform is provided for the fields of food and medicine.

The utility model relates to air sampling technical field, concretely relates to a kind of air sampling multistage dehumidification device for rail transit, including sampling collection pipe, filter module, U-shaped tube, gas analysis module in turn along gas flow direction;It further includes primary water droplet flow guide structure, secondary extrusion structure, tertiary discharge structure, respectively for promoting the condensation of water vapor in sampling collection pipe into water droplet and flow guide discharge, for extruding the adsorbed water of filter sponge adsorption in filter module, for collecting the water drop of filter sponge seepage or extrusion.The utility model adds primary water droplet flow guide structure, secondary extrusion structure, tertiary discharge structure in correspondence in sampling collection pipe, filter module, U-shaped tube, carries out flow guide collection to water vapor water droplet etc., multiple protection is realized, prevent water droplet flow into gas analysis module, thus can avoid affecting gas monitoring work and avoid causing economic loss.

In one embodiment, a system includes a flow cell assembly having a flow cell body with a base having an opening allowing sheathed sample fluid to flow out, a bracket coupled to the flow cell body, a flat mirror mounted to the bracket, a hardware triggered camera coupled to the bracket on one side, and a diffused light emitting diode strobe light coupled to the bracket on an opposite side. The camera and strobe light are pointed at the mirror on opposite sides. Activation of the diffused LED strobe light generates a diffused strobe light into the mirror backlighting a droplet stream. Triggering of the camera is synchronized with the generation of the strobe light to periodically capture a brightfield still image of the droplet stream. The image can be analyzed for measured jet breakoff point and measured droplet interval point for visual feedback control of the droplet stream.

This invention discloses a method for preparing diether fluorene using microchannel reaction, comprising the following steps: (1) mixing 9-fluorenone, phenoxyethanol, and a co-catalyst at a certain temperature to form a uniform mobile phase 1, and using a strong acid catalyst as a mobile phase 2; (2) injecting mobile phase 1 and mobile phase 2 into a microchannel at a certain flow rate ratio and total volumetric flow rate to form a droplet flow for reaction, and diffusing the obtained product to a liquid-liquid separator, where the liquid and liquid phases are separated to obtain an ethyl acetate phase and an aqueous phase. The aqueous phase is used to recover the strong acid, and the ethyl acetate phase is concentrated and crystallized to obtain high-purity diether fluorene. This invention is the first to utilize microfluidic technology to prepare diether fluorene using 9-fluorenone and phenoxyethanol as the main reactants. The process is simple, energy-efficient, has a short reaction time, is green and safe, and is economical, making it suitable for large-scale production.

The application relates to the field of microfluidic technology, in particular to a portable droplet microfluidic device which is small in size and convenient to carry. The parameter of the droplet is monitored by using a triboelectric sensing technology, and the monitoring precision is improved. The portable droplet microfluidic device comprises a driving assembly and a microfluidic chip, wherein the microfluidic chip comprises a channel and an electrode assembly which are arranged in a stacking mode along a first direction, the electrode assembly comprises first electrodes and second electrodes which are arranged at intervals along a second direction; along the first direction, the channel at least partially overlaps the first electrodes, and the channel at least partially overlaps the second electrodes; the driving assembly comprises a piezoelectric liquid pump and a piezoelectric gas pump, the piezoelectric liquid pump is used for pumping liquid into the channel, and the piezoelectric gas pump is used for pumping gas into the channel; the driving assembly is used for generating a droplet in the channel; when the droplet flows along the channel and sequentially passes through the first electrodes and the second electrodes, the first electrodes generate a first electric signal, and the second electrodes generate a second electric signal.

The application relates to the technical field of cell sorting, and discloses a droplet sorting system, which comprises a flow channel assembly, a fluorescence signal detection device and a sorting device. The flow channel assembly defines a droplet flow channel for droplet flow, a first liquid outlet flow channel and a second liquid outlet flow channel. The fluorescence signal detection device is used for exciting droplets to emit fluorescence and marking droplets meeting fluorescence conditions as target droplets. The sorting device is arranged corresponding to the liquid outlet section of the droplet flow channel. Target droplets flowing through the liquid outlet section of the droplet flow channel enter the first liquid outlet flow channel under the deflection of the sorting device, and non-target droplets enter the second liquid outlet flow channel. The application also discloses a droplet sorting method.

The invention is suitable for the technical field of computers, and provides a droplet flow velocity determination method, terminal equipment and a computer program product, and the method comprises the steps: obtaining a continuous image sequence of droplets; inputting the continuous image sequence into a target detection model for processing to obtain liquid drop information of each liquid drop in each frame of liquid drop image in the continuous image sequence; determining a cross-frame associated droplet combination based on the droplet information of each droplet in each frame of droplet image; and based on the liquid drop information of the liquid drop combination, calculating to obtain speed information of the liquid drop combination. Through the continuous image sequence and model processing, the droplet information can be accurately extracted, and the droplet information of any droplet can be identified in real time to determine the cross-frame associated droplet, so that the droplet speed is accurately determined, and the problems of inaccurate detection and poor detection accuracy under the conditions of illumination change, background noise and droplet deformation in the prior art are solved. And missing detection and false detection are easy to occur in a high-density and high-speed scene, and reliable real-time tracking is difficult to realize.

Microfluidic Droplet Apparatus and Method Disclosed is a droplet transfer module configured to engage a multiwell substrate. The DTM comprises: transfer face; at least one primary channel; secondary channel portion at the transfer face, configured to form at least one secondary channel when the droplet transfer module is engaged with the MWP, comprising at least one secondary channel access portion to permit flow of droplet fluid in the secondary channel portion; and at least one transfer channel connected between the primary channel and the transfer face, the at least one transfer channel comprising: first transfer channel connection portion connected to the primary channel, configured to receive a droplet from the droplet fluid in the primary channel; and second transfer channel connection portion located at the transfer face and connected to the secondary channel portion, configured to allow exit of a droplet from transfer channel to corresponding well of the multiwell substrate engaged with the DTM.

The application discloses a super-hydrophobic needle and a preparation method and device thereof, and a micro-droplet generating device and method, and relates to the technical field of micro-fluids; specifically, in the application, the injection needle is modified by a laser light filament to obtain a modified needle, and then the modified needle is subjected to heat treatment to obtain a super-hydrophobic needle. The injection needle is modified by the laser light filament, the characteristics of the laser light filament are utilized, the inner surface of the injection needle is rapidly modified, the inner surface of the injection needle is converted into a super-hydrophobic surface by cooperating with a heat treatment method, the adhesion force acting on the liquid droplets flowing out of the injection needle is greatly reduced, and only a physical treatment method is adopted, so that the processing is simple and quick while avoiding the introduction of any chemical substances. Further, the size of the injection needle and the flow rate of the liquid can be selected to control the volume and generation frequency of the micro-droplets.

A droplet separation device includes a microchannel that has an upstream portion, a chamber portion which is provided downstream with respect to the upstream portion and has a cross sectional area larger than a cross sectional area of the upstream portion, a branch portion which is provided downstream with respect to the chamber portion, and two branch channels which are branched by the branch portion, where droplets flow together with a first fluid, a droplet interval adjustment channel that is connected to the upstream portion to join the upstream portion and allows a second fluid having the same formulation as the first fluid to flow into the upstream portion, an electric field generation electrode that is provided to be adjacent to the chamber portion and generates an electric field by being controlled by an external signal to apply a voltage, and a plurality of reference electrodes that are provided to generate an electric field gradient in the chamber portion in accordance with the generation of the electric field by the electric field generation electrode, in which the branch portion has an asymmetric shape in which the droplets flow into only one of the two branch channels without being crushed in a case where the electric field generation electrode generates no electric field.

The invention relates to an intracellular biomass detection device and method based on droplet flow control in the technical field of biological detection. The intracellular biomass detection device comprises at least one detection module. The detection module comprises a perforation unit, a fluid coupling unit, a nanopore unit, a driving unit and a signal acquisition unit. The perforating unit is used for forming nanoscale reversible holes in a cell membrane through electric pulses. The fluid coupling unit comprises at least one three-dimensional spiral microfluidic channel; and the microfluidic channel is used for guiding molecules in the cells out of the perforation unit in a one-way manner. By combining an electroporation sampling-microfluidic channel fluid coupling-solid nanopore detection technology, low-disturbance sampling, one-way transportation and single-molecule resolution detection of charged molecules in cells are realized, and high-sensitivity, low-disturbance and high-throughput detection performance can be realized while high cell activity is maintained. And a novel integrated analysis platform is provided for drug screening, metabolism regulation and disease model research.

The embodiment of the invention is suitable for the technical field of biomedicine and image processing, and provides a droplet counting method and device and droplet counting equipment, and the method comprises the steps: collecting a droplet flow image, the droplet flow image comprises multiple frames of images, and any frame of image comprises a preset region of interest; performing liquid drop detection in the region of interest of the current frame image to obtain a liquid drop detection result of the current frame image; under the condition that the liquid drop detection result of the current frame image represents that liquid drops exist in the current frame image, determining a count value of the liquid drops in the current frame image based on the liquid drop detection result of the current frame image and a liquid drop detection result of a previous frame image; and counting the counting values of the liquid drops in the multiple frames of images to obtain a liquid drop counting result. By the adoption of the method, the liquid drops in the high-speed liquid drop flow field can be accurately counted, and repeated counting or missed counting is avoided.

A droplet ejection head includes one or more actuator components, an inlet path to supply fluid to and an outlet path to remove fluid from the actuator components. The actuator components include fluid chambers, each having at least one nozzle and being actuable to eject one or more droplets via the nozzle. The fluid chambers are connected to the inlet path and to the outlet path. The outlet path includes one or more heat exchangers downstream of the actuator components and one or more actuator drive electronic components adjacent to each heat exchanger. The heat exchangers include one or more heat exchanger fluid paths. In use heat transfers from the actuator drive electronic components to the heat exchangers and is removed via the return fluid. An area demarcated by the actuator drive electronic components is substantially contained within an area in the same plane demarcated by the heat exchanger fluid paths.

The invention discloses a single-solid-core liquid drop automatic sorting method based on image recognition and dielectrophoretic force, which comprises the following steps: establishing a labeling data set containing water-oil liquid drops and single-solid-core solid-water-oil liquid drops, and training a liquid drop classification model; the injection pump is started to generate liquid drop flow, the signal generator is started to generate alternating signals, the high-voltage amplifier is started to amplify the alternating signals, images are collected in real time and recognized through the liquid drop classification model, and when single-solid-core solid-water-oil liquid drops are detected, the computer outputs digital signals to the microcontroller. The microcontroller outputs a high-level electric signal to the direct-current amplifier, the high-voltage switching device is turned on, high voltage is loaded to the dielectrophoresis separation area, the dielectrophoresis electric field is activated, and the single-solid-core solid-water-oil liquid drops are deflected to enter the collection channel. The technical problem that real-time efficient separation is difficult to achieve due to the fact that solid water-oil liquid drops and water-oil liquid drops are mixed in the current micro-flow control preparation process is solved, and the purity and the separation efficiency of the single-solid-core liquid drops are remarkably improved.