Microfluidic reaction chip, liquid droplet positioning control system based on same and control method

A microfluidic reaction and positioning control technology, applied in fluid controllers, chemical instruments and methods, laboratory utensils, etc., can solve the problem of inability to observe the driving process of microdroplets, and achieve the effect of improving the success rate

Pending Publication Date: 2018-12-28
ZHONGKAI UNIV OF AGRI & ENG
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] In order to solve the above-mentioned technical defects of being unable to observe the driving process of micro-droplets, the present invention discloses a microfluidic reaction chip and its droplet po

Method used

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  • Microfluidic reaction chip, liquid droplet positioning control system based on same and control method
  • Microfluidic reaction chip, liquid droplet positioning control system based on same and control method
  • Microfluidic reaction chip, liquid droplet positioning control system based on same and control method

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Embodiment

[0064] Such as figure 2 , image 3 As shown, a microfluidic reaction chip is characterized in that: it includes a square digital microfluidic chip 1, and the digital microfluidic chip 1 includes an upper pole plate and a lower pole plate, and the upper pole plate is sequentially arranged from top to bottom Composed of an upper substrate 13, a zero electrode layer 14 and an upper hydrophobic dielectric layer 15, the lower plate is composed of a lower hydrophobic dielectric layer 16, a driving electrode layer 17 and a lower substrate 18 from top to bottom; wherein, as Figure 5 As shown, the driving electrode layer 17 is composed of eight driving electrode units; seven droplet channels 11 are formed between the upper plate and the lower plate, and the junction of each of the droplet channels 11 is Reaction tank 12; a titration hole 19 is provided above each of the droplet flow channels 11, and the titration hole 19 runs through the upper plate; one of the droplet flow channels...

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Abstract

The invention discloses a microfluidic reaction chip, a liquid droplet positioning control system based on the same and a control method. The microfluidic reaction chip is characterized by comprisinga digital microfluidic chip, wherein the digital microfluidic chip comprises an upper polar plate and a lower polar plate, at least three liquid droplet flow channels are formed between the upper polar plate and the lower polar plate, and a reaction tank is formed at the intersection of the liquid droplet flow channels; a titration hole is formed in the upper part of each liquid droplet flow channel and penetrates the upper polar plate; at least one of the liquid droplet flow channel is an output flow channel, and the others are input flow channels. The liquid droplet flow channels of the digital microfluidic chip are filled with black liquid insoluble with liquid droplets, an infrared laser module and a light intensity sensing module are added to the two ends of the digital microfluidic chip, a driving process of micro-droplets can be observed clearly and accurately, and success rate of complicated micro-droplet transportation and application is greatly increased.

Description

technical field [0001] The invention relates to the technical field of digital microfluidics, in particular to a microfluidic reaction chip, a droplet positioning control system and a control method thereof. Background technique [0002] Electrowetting is a technology that changes the surface tension between a liquid and a solid by adjusting the potential applied between the liquid-solid electrodes, thereby changing the contact angle between the two; dielectric wetting is a technique in electrowetting technology It is developed on the basis of improvement. This technology is to avoid the electrolytic reaction that often occurs in electrowetting by adding a layer of dielectric insulating material with a thickness of micron between the driving electrode and the electrolyte. The wetting characteristics of the surface of the dielectric layer will also change. [0003] The digital microfluidic technology based on the dielectric wetting effect is a new technology that can manipul...

Claims

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Application Information

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IPC IPC(8): B01L3/00
CPCB01L3/502792B01L2300/165B01L2300/0645B01L2300/06B01L2400/0415B01L2200/143
Inventor 罗智杰刘双印揭章斌徐龙琴曹亮呼增
Owner ZHONGKAI UNIV OF AGRI & ENG
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