3results about How to "Facilitated ionization" patented technology

The application discloses a low-temperature ion nitriding method and application. The low-temperature ion nitriding method comprises the following steps: under a selected temperature condition, ion etching treatment is performed on the surface of a workpiece by adopting an arc-enhanced glow discharge process, and then plasma nitriding treatment is performed on the workpiece by adopting an arc-enhanced plasma process to obtain a nitriding workpiece; wherein, a positive and negative alternating voltage is applied to the workpiece in the arc-enhanced plasma process. The low-temperature ion nitriding method provided by the application can realize nitriding at a lower temperature, effectively improves the deformation degree of the workpiece, and is widely applicable to surface strengthening of cutters, molds and metal parts.

In this embodiment of the environmental ionization experiment, the abundance of background chemicals relative to the target ions is reduced by pulsed application of the carrier gas used to generate the excited substance directed toward the sample. The excited substance is progressively directed toward the sample, thereby reducing the overall abundance of background chemicals introduced into the ionization region. In this embodiment of the environmental ionization experiment, the combination of sample stepping before the excited substance and pulsed application of the carrier gas used to generate the excited substance improves the detection sensitivity.

The invention discloses a dapoxetine hydrochloride tablet pharmaceutical composition and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. The composition comprises dapoxetine hydrochloride, sodium bicarbonate, a filler, a disintegrating agent and a lubricant. Aiming at the problems of low dissolution rate, poor stability, complex preparation process and the like of dapoxetine hydrochloride tablets in the prior art, sodium bicarbonate is introduced as a key auxiliary material, a raw material pretreatment process is optimized, a traditional adhesive is omitted, and the dissolution rate and the preparation stability are remarkably improved. The preparation method comprises the following steps: pre-drying the filling agent (microcrystalline cellulose) until the water content is less than or equal to 2.0%, sieving sodium bicarbonate with a sieve of more than 100 meshes, mixing the sodium bicarbonate with dapoxetine hydrochloride and the lubricant, directly tabletting, and then coating. The preparation method is simple in process, low in cost and suitable for industrial production, and the obtained tablet is high in dissolution rate and excellent in stability under the conditions of high temperature, high humidity and illumination.