Mass spectrometry system and working method thereof

一种质谱分析、质谱仪的技术，应用在分析材料、通过电磁手段进行材料分析、粒子分离管等方向，能够解决无法保证分析灵敏度和重复性、易挥发、无法实现高通量分析等问题，达到有利于离子化、消除干扰、保障灵敏度和重复性的效果

Active Publication Date: 2017-07-18
CHINA INNOVATION INSTR CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, only 3-10 μL of liquid sample is dropped on the hydrophilic area of ​​the paper base, which is extremely volatile and cannot keep each hydrophilic area wet during array analysis, which means that the analysis sensitivity and repeatability cannot be guaranteed, and high throughput cannot be achieved. analyze

Method used

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  • Mass spectrometry system and working method thereof
  • Mass spectrometry system and working method thereof
  • Mass spectrometry system and working method thereof

Examples

Experimental program
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Embodiment 1

[0031] figure 1 Schematically provides a simplified structural diagram of the mass spectrometry system of the embodiment of the present invention, as figure 1 As shown, the mass spectrometry system includes:

[0032] An ion source and a mass spectrometer, the ion source and the mass spectrometer are respectively arranged on both sides of the sampling device;

[0033] figure 2 Schematically provides a simplified structural diagram of the sampling device of the embodiment of the present invention, as figure 2 As shown, the sampling device includes:

[0034] Guide rail 11; said guide rail is arranged horizontally

[0035] Support 21, the support is suitable for moving horizontally on the guide rail;

[0036] The carrier 31, the carrier is vertically arranged, and the left and right ends are fixed on the bracket, and the carrier is made of hydrophobic material;

[0037] At least two conveying parts, the conveying part adopts hydrophilic material, including a first part 32 ...

Embodiment 2

[0045] The mass spectrometry system of the embodiment of the present invention is different from Embodiment 1 in that:

[0046] 1. No more through-holes are provided on the carrier.

[0047] 2. The guide rail is arranged vertically, the upper and lower ends of the carrier are fixed on the bracket, and the first part is arranged on the carrier from top to bottom. By moving the carrier up and down, different first parts are respectively located between the ion source and the mass spectrometer.

Embodiment 3

[0049] The mass spectrometry system of the embodiment of the present invention is different from Embodiment 1 in that:

[0050] Cut out rectangular filter paper, and there are multiple band-like structure filter paper connected with the rectangular filter paper on the side of the rectangular filter paper; print paraffin on the rectangular filter paper, but leave a number of circular areas on the rectangular filter paper, and the circular areas are connected with the bands. The connecting part of the filter paper with the shape structure is reserved, and no paraffin is printed in these reserved areas; the circular area is used as the first part, and the area where the paraffin is printed is used as the carrier for the first part.

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PUM

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Abstract

The invention provides a mass spectrometry system and a working method thereof. The mass spectrometry system includes an ion source, a sampling device and a mass spectrometer. The sampling device includes a guide rail; a support suitable for moving on the guide rail; a bearing piece made of hydrophobic material and having two ends fixed on the support; at least two conveying parts made of hydrophilic material and each including a first part arranged on the bearing piece and a second part connected with the first part and protruding into a container; the container arranged on the support and accommodating to-be-detected samples; a drive module driving the support to move on the guide rail so as to enable the central axis of an exit port of the ion source to penetrate through the first part, wherein the adjacent conveying parts are not in contact. The system provided by the invention has advantages of good accuracy, high flexibility and the like.

Description

technical field [0001] The invention relates to mass spectrometry, in particular to a mass spectrometry system and its working method. Background technique [0002] The open mass spectrometry ion source is a new type of mass spectrometry ion source that can be used in an open environment at atmospheric pressure. It does not require complicated sample pretreatment, and can realize in-situ, real-time, and rapid ionization of samples in a very short time. It has the advantages of small size, portability, detection With the advantages of low cost and wide application range, it has broad application prospects in many fields such as food testing, drug analysis, environmental monitoring, public safety and clinical diagnosis. [0003] At present, when using an open mass spectrometer ion source (DBDI, LTP, etc.) for liquid sample analysis, the sample is generally injected with a capillary or a glass rod. Due to the presence of a large number of high-energy particles in the ejected p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): H01J49/00H01J49/04G01N27/64
CPCG01N27/64H01J49/0031H01J49/0409H01J49/0431H01J49/0413G01N33/6848H01J49/426H01J49/062G01N33/543
Inventor 赵鹏闻路红周镇宇史振志陈瑞强
Owner CHINA INNOVATION INSTR CO LTD
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