1066 results about "Thermal cycle" patented technology

A method of processing data associated with fluorescent emissions from a microfluidic device. The method includes performing an auto-focus process associated with a first image of the microfluidic device and performing an auto-exposure process associated with the first image of the microfluidic device. The method also includes capturing a plurality of images of the microfluidic device. The plurality of images are associated with a plurality of thermal cycles. The method further includes performing image analysis of the plurality of captured images to determine a series of optical intensities and performing data analysis of the series of optical intensities to provide a series of change in threshold values.

An instrument for performing highly accurate PCR employing a sample block in microtiter tray format. The sample block has local balance and local symmetry. A three zone film heater controlled by a computer and ramp cooling solenoid valves also controlled by the computer for gating coolant flow through the block controls the block temperature. Constant bias cooling is used for small changes. Sample temperature is calculated instead of measured. A platen deforms plastic caps to apply a minimum acceptable threshold force for seating the tubes and thermally isolates them. A cover isolates the block. The control software includes diagnostics. An install program tests and characterizes the instrument. A new user interface is used. Disposable, multipiece plastic microtiter trays to give individual freedom to sample tubes are taught.

It is an object of the invention to provide a curable resin composition excellent in mechanical strength, heat resistance, moisture resistance, flexibility, resistance to thermal cycles, resistance to solder reflow, dimensional stability, and the like after curing and providing high adhesion reliability and conduction reliability and an adhesive epoxy resin paste, an adhesive epoxy resin sheet, a conductive connection paste, and a conductive connection sheet using the curable resin composition, and an electronic component joined body. The invention relates to a curable resin composition, which contains an epoxy resin, a solid polymer having a functional group to react with the epoxy group and a curing agent for an epoxy resin, no phase separation structure being observed in a matrix of a resin when a cured product is dyed with a heavy metal and observed with a transmission electron microscope.

A thermal cycling device (3) device a number of fixed thermal zones (11, 12, 13) and a fixed conduit (10) passing through the thermal zones. A controller maintains each thermal zone including its section of conduit (10) at a constant temperature. A series of droplets flows through the conduit (10) so that each droplet is thermally cycled, and a detection system detects fluorescence from droplets at all of the thermal cycles. The conduit is in a single plane, and so a number of thermal cycling devices may be arranged together to achieve parallelism. The flow conduit comprises a channel (17) and a capillary tube (10) inserted into the channel. The detection system may perform scans along a direction to detect radiation from a plurality of cycles in a pass.

An exhaust gas purifying apparatus is provided which includes a honeycomb structure used as a filter to capture particulates in exhaust gas from an internal combustion engine such as diesel engine and as a carrier of a catalyst to convert the exhaust gas. The honeycomb structure is formed from a composite material comprising ceramic particles and crystalline silicon. The particulates captured by the honeycomb structure are removed by combustion at a temperature of 250 to 800° C., thereby, even if a relatively low temperature is distributed or a heat cycle has been repeated from a long term, thermal stress is prevented from being stored, cracking is prevented and thermal shock resistance is thus improved.

Systems, methods and apparatuses for manufacturing dosage forms, and to dosage forms made using such systems, methods and apparatuses are provided. Novel compression, thermal cycle molding, and thermal setting molding modules are disclosed. One or more of such modules may be linked, preferably via novel transfer device, into an overall system for making dosage forms.

The present invention provides a thermal cycling device including: a heat exchanger body (3) having a longitudinal axis and longitudinally divided to provide at least two segments which are able to be heated to different temperatures so that said body has peripheral surfaces of different temperatures; a conduit (2) extending about said body so as to be in thermal contact with said peripheral surfaces; a first delivery device to deliver a first fluid to said conduit to cause said fluid to pass therealong and therefore change in temperature as the fluid passes said segments; and a second delivery device to deliver a second fluid to said conduit so as to flow with said first liquid and therefore also change in temperature. The fluid then leaves the device by conduit (4). The invention also is directed to an injector means for use in the thermal cycling device of this invention, comprising: a septum (26); a needle (20) which is able to pierce the septum; a reservoir (27) in fluid contact with septum (26) having an inlet (28) and an outlet (30); wherein when in use, the needle is urged through the fluid in said reservoir and then through the septum while continually purging the reservoir with said purge fluid. The present invention also includes a scanning detector (5) fitted to the outside of the heat exchange body (3) which monitors the course of reaction inside the conduit (2).

A thermal cycle system and method suitable for mass production of DNA comprising a temperature control body having at least two sectors. Each sector has at least one heater, cooler, or other means for changing temperature. A path traverses the sectors in a cyclical fashion. In use, a piece of tubing or other means for conveying is placed along the path and a reaction mixture is pumped or otherwise moved along the path such that the reaction mixture is repetitively heated or cooled to varying temperatures as the reaction mixture cyclically traverses the sectors. The reaction mixture thereby reacts to form a product. In particular, polymerase chain reaction reactants may continuously be pumped through the tubing to amplify DNA. The temperature control body is preferably a single aluminum cylinder with a grooved channel circling around its exterior surface, and preferably has wedge-shaped or pie-shaped sectors separated by a thermal barrier.

Systems, methods and apparatuses for manufacturing dosage forms, and to dosage forms made using such systems, methods and apparatuses are provided. Novel compression, thermal cycle molding, and thermal setting molding modules are disclosed. One or more of such modules may be linked, preferably via novel transfer device, into an overall system for making dosage forms.

A semiconductor device has an insulating substrate with conductor patterns bonded to and formed on both the top and bottom surfaces of a ceramic substrate. Soldering is provided between the conductor pattern on the top surface side and a heat developing chip component such as a power semiconductor element is mounted thereon. Between the conductor pattern on the bottom surface side and a heat dissipating metal base plate, each of four corners of the ceramic substrate is chamfered to form a chamfered section with a chamfered dimension of 2 to 10 mm. Alternatively, slits can be formed at the four corners on the bottom surface side. Moreover, the thickness of the conductor patterns can be controlled in relation to the ceramic substrate. These configurations relax the stress concentration created in the soldered section due to a thermal cycle.

A multi-layer aluminum brazing sheet including a core layer, interliner, braze clad layer and a sacrificial layer, in which the post-braze strength of the brazing sheet is optimized by controlling the manganese (Mn), silicon (Si), copper (Cu) and magnesium (Mg) contents of the core layer and the Mn, Si and Cu content of the interliner and the Mn, Si and Zn content of the sacrificial layer and the specifics of the braze thermal cycle. The brazing sheet maintains corrosion resistance, while optimizing post-braze strength, by utilizing 0.5 wt. % to 1.2 wt. % Cu in the interliner. Further, the interliner and sacrificial layer of the brazing sheet contain low or no magnesium to maintain the brazing sheet's braze-ability.

A seal for devices such as a solid oxide fuel cells. The seal is a double seal having a first sealing material having a first preselected characteristic and a second sealing material having a second sealing characteristic. In one embodiment of the invention the first sealing material is a compressive sealing material and the second sealing material is a hermetic sealing material. In some embodiments a dimensional stabilizer may also be included as a part of the seal. In use these double seals provide superior thermal cycling stability in electrochemical devices where gasses must be separated from each other.

A system and method for controlling a thermal dynamic cycle engine, such as a Stirling engine. The system includes a controller able to execute a program to alter certain aspects of the system to provide for a maximum power transfer and substantially stall free start up of the thermal dynamic cycle engine. Generally the controller is able to alter the current load to achieve a selected stroke length, pattern or temperature of a heater head of the engine. The system allows for generally stall free start-up and continuous control for maximum power (with maximum power factor) transfer from the thermal cycle engine or the associated alternator.

Metal-ceramic composite materials made by an infiltration technique have now been prepared using microwave energy as the heat source for thermal processing. Specifically, microwave energy has been used to heat and melt a source of silicon metal, which in turn has infiltrated carbon-containing preforms to make reaction-bonded silicon carbide composites, respectively. Both the time-at-temperature as well as the overall thermal cycle time have been greatly reduced, implying a large cost savings.

The invention discloses a halogen-free fire-retardant high heat conducting insulating resin composition and a heat dissipation metal-base copper clad plate (CCL). The composition comprises the following components in parts by weight: 10-45 parts of halogen-free epoxy resin, 0-15 parts of thermoplastic resin and/or synthetic rubber, 0.1-5 parts of curing agent, 0.02-1 parts of accelerator, 0.5-1 parts of antioxidant and 25-80 parts of heat conducting filler. The halogen-free fire-retardant high heat conducting insulating resin composition of the invention adopts high heat conducting filler, and the cured composition shows good thermal conductivity, electric insulativity and welding heat resistance as well as high adhesive force. The invention also discloses a heat dissipation metal-base CCL prepared by using the above halogen-free fire-retardant high heat conducting insulating resin composition, which has high thermal conductivity and high peel strength, does not have the problems of peel-off and deterioration even being subjected to thermal cycle of quick heating and quick cooling, and also has high electrical breakdown resistance, good heat resistance and soldering resistance and the like, and the flame retardant rating of the heat dissipation metal-base CCL reaches UL-94V0.