The invention discloses a
medicine of
Agomelatine for treating depression, in particular an
Agomelatine crystal and a
medicine composition thereof. The
Agomelatine crystal is irradiated by using Cu-
K alpha; and an X-
ray powder diffraction spectrum expressed by the degree of 2theta of the Agomelatine
crystal has characteristic
diffraction peaks at positions of 12.84, 13.84, 16.14, 14.18, 18.56, 19.12, 20.86, 21.20 and 23.84, and an
infrared absorption spectrum of the Agomelatine crystal has characteristic
diffraction peaks approximately at position of 3234, 3060, 2940, 1638, 1511, 1436, 1249, 1215, 1184, 1032, 908, 828, 755 and 588cm-1. The DSP heat absorption transition is 97.6 DEG C. The invention further discloses application of the
medicine composition containing the Agomelatine crystal as an active effective component to the preparation of medicines for treating the depression.