Whitening and acne removing oil control composition, skin care product and preparation method

Abstract

The invention discloses an oil-control composition for whitening and removing acnes. The oil-control composition comprises a raspberry extract, a mangnolia officinalis extract and a natural active matter, the weight ratio of the raspberry extract to the mangnolia officinalis extract to the natural active matter is (0.1-1): (1-5): 1. According to the invention, the raspberry ketone, the magnolia bark extract and the natural active matters are combined, so that the exuberant grease secretion of skin can be fundamentally improved, and inflammation and acne of the skin can be inhibited. Under the optimal weight ratio, the oil can be controlled for a long time, the oil secretion is effectively regulated, the pores are refined, the acne breeding is prevented, and the skin is smoother and finer. The problems that part of current oil control raw materials treat the symptoms but not the root causes, the oil control effect is not lasting, and part of raw materials cause skin thinning and drying and have large irritation to the skin can be solved.

Description

Technical Field

[0001] The present invention relates to the field of cosmetics, and particularly to an oil-control composition for whitening and removing acne, skin care products and a preparation method thereof. Background Art

[0002] Excessive secretion of skin oil will clog pores, cause excessive reproduction of bacteria, and bacterial infection will lead to skin inflammation problems. In severe cases, dark red nodules, cysts, and even abscesses will appear. Once the abscess ruptures, it will form a sinus tract, bringing serious acne problems. Existing methods only control the oil secretion condition of the surface skin, without deeply analyzing the reasons for excessive skin oil secretion. And during the process of controlling oil secretion by traditional methods, the skin barrier is damaged, making the skin more sensitive and exacerbating skin problems. Therefore, it is crucial to develop an oil-control and skin-care composition that is non-irritating to the skin and treats both the symptoms and the root causes.

[0003] Chinese Patent Invention CN111297788A discloses a whitening and freckle-removing essence and a preparation method thereof, introducing whitening components such as raspberry ketone, niacinamide, arbutin, and bisabolol, which has the effect of fading freckles and making the skin fair, bright and translucent, but does not involve the technical effect of oil control. Chinese Patent Invention CN118975952A discloses an organic acid thermosensitive gel and a preparation method and application thereof, combining poloxamer 407, a gel-promoting agent, and an organic acid, and designing a thermosensitive gel for improving abnormal keratinization of the sebaceous follicle duct orifice, inhibiting sebum secretion, reducing the number of Propionibacterium acnes, alleviating local inflammation, and accelerating keratin renewal through formula and process screening. However, organic acids need to be added, which is somewhat irritating to the skin and will damage the skin barrier. Summary of the Invention

[0004] In order to develop an oil-control and skin-care composition that is non-irritating to the skin and treats both the symptoms and the root causes, the first aspect of the present invention provides an oil-control composition for whitening and removing acne, comprising raspberry (RUBUS IDAEUS) extract, magnolia (Magnolia officinalis Rehd. Et Wils.) extract, and natural active substances; the weight ratio of the raspberry extract, magnolia extract, and natural active substances is (0.1-1):(1-5):1.

[0005] As a preferred embodiment, the weight ratio of the raspberry extract, magnolia extract, and natural active substances is (0.1-0.3):(1-3):1.

[0006] The weight ratio of the raspberry extract, magnolia extract, and natural active substances is 0.2:1:1.

[0007] During the experiment, the inventor found that existing skin oil control methods use cooling agents, astringents, etc. to shrink pores, but the effect is not lasting, treating only the symptoms rather than the root cause. The effect of shrinking or astringing pores will disappear within a short period of time, and the true oil control effect cannot be achieved. In addition, there are methods that use keratolytic agents to remove excess cutin and prevent pore blockage, but this will cause the skin cutin to become thinner, making the skin sensitive and the effect being poor.

[0008] In the present invention, the combination of raspberry ketone, magnolia bark extract and natural active substances can fundamentally improve the problem of excessive sebum secretion in the skin, inhibit inflammation and acne problems of the skin. The possible reason is speculated as follows: Acne is caused by high concentrations of sebum and cutin blocking pores, forming whiteheads or blackheads. The whiteheads or blackheads provide an anaerobic and lipid-rich environment, stimulating the proliferation of Propionibacterium acnes. Chemotactic factors are produced in the surrounding dermis, leading to inflammatory lesions. The natural active substances inhibit the proliferation of sebum cells, thereby reducing the oil content of the skin. Combining with the antibacterial effect of raspberry ketone and magnolia bark extract, the activity of Propionibacterium acnes is inhibited, thus inhibiting the proliferation of bacteria. And the inventor further found that the magnolia bark extract is insoluble in water, further prolonging the lasting oil control effect of the composition in skin cells. When applied to cosmetics, it has good oil control and acne removal effects, and the skin is not irritated and the skin barrier function will not be damaged.

[0009] As a preferred embodiment, the raspberry extract includes raspberry ketone and a diol compound.

[0010] As a preferred embodiment, the diol compound is hexanediol. Preferably, the hexanediol is 1,2-hexanediol; the weight ratio of raspberry ketone to the diol compound is 0.4:(0.1 - 0.3).

[0011] As a preferred embodiment, the weight ratio of raspberry ketone to the diol compound is 0.4:(0.1 - 0.2).

[0012] As a preferred embodiment, the magnolia extract includes magnolia bark extract and butanediol, and the weight ratio of magnolia bark extract to butanediol is (0.1 - 1):1.

[0013] As a preferred embodiment, the magnolia extract includes magnolia bark extract and butanediol, and the weight ratio of magnolia bark extract to butanediol is (0.1 - 0.5):1.

[0014] As a preferred embodiment, the purity of magnolol in the magnolia bark extract is 95 - 99%.

[0015] As a preferred embodiment, the purity of magnolol in the magnolia bark extract is 98%.

[0016] As a preferred embodiment, the natural active substances include one or a combination of several of white willow bark extract, tea extract, gotu kola extract, Cladosiphon okamuranus extract, Coffea arabica seed extract, bergamot leaf extract, and Pinus densiflora leaf extract.

[0017] As a preferred embodiment, the natural active substances include Salix alba L. bark extract, Camellia sinensis extract, CENTELLA ASIATICA extract, CLADOSIPHON OKAMURANUS extract, COFFEA ARABICA seed extract, CITRUSAURANTIUM BERGAMIA leaf extract, and PINUS DENSIFLORA leaf extract.

[0018] White willow bark extract can promote skin cell renewal, condition skin physiological activity, make the skin smooth, delicate and full of vitality, restore skin immunity, resist external attacks, antibacterial and anti-inflammatory. Compared with industrial salicylic acid, the salicylic acid in white willow bark extract is a natural extract without any added ingredients, which can protect the skin. White willow bark extract has a wide range of effects on inhibiting human enzymes. It can inhibit all three metalloproteinases at low concentrations. The activation of metalloproteinases is directly related to skin aging. Coupled with the strong elimination of superoxide free radicals by white willow bark extract, it has a very good inhibitory effect on melanocytes. Tea extract has antioxidant effects. On the one hand, it can inhibit the activity of oxidase, such as tyrosinase which is crucial for melanin production, and reduce melanin production. On the other hand, tea polyphenols can also reduce the already produced melanin and fade skin color. Asiaticoside in centella asiatica can promote the vitality of scar fibroblasts and has the effect of removing scars. It has a very good polymerization effect with phospholipid substances and has an obvious effect on eliminating acne. The ionic components in kelp can promote the production of skin collagen. When applied to skin care products, it can improve skin dry lines, fade aging fine lines, refine pores, slow down skin aging, and make the skin more delicate and plump. The content of methionine and cystine in kelp is rich, which can effectively regulate sebum secretion, refine pores, prevent the growth of acne, and make the skin smoother and more delicate. Make the skin smoother, more delicate, firm and elastic. At the same time, it can enhance skin tolerance and help resist the invasion of external harmful substances, so that the skin can always maintain a good state. Coffea arabica seed extract can inhibit trypsin, that is, it can protect the elastic protein fibers of the cortex, thus avoiding the formation of wrinkles. Coupled with the strong elimination of several free radicals by the extract and its ability to inhibit the production of nitrogen dioxide, it can be used as an antioxidant and anti-aging agent for cosmetics. Bergamot leaf extract can increase skin moisture content, improve rough and dry skin texture, and make the skin feel delicate and smooth. Pinus densiflora leaf extract can inhibit metalloproteinases and can be used as an anti-inflammatory agent.

[0019] The second aspect of the present invention provides a skin care product comprising the above-mentioned oil-control composition for whitening and removing acne.

[0020] As a preferred embodiment, the skin care product includes but is not limited to facial cleanser and body wash.

[0021] As a preferred embodiment, the preparation raw materials include, by weight percentage, 3-5% of the cleansing phase, 0.3-0.8% of raspberry extract, 1-3% of magnolia officinalis extract, 0.1-1% of natural active substances, 0.1-0.6% of stabilizer, and the water phase is made up to 100%.

[0022] As a preferred embodiment, the cleansing phase includes a thickening agent, citric acid and sodium chloride, and the weight ratio of the thickening agent, citric acid and sodium chloride is (1-2):(1.5-2):(1.5-2).

[0023] As a preferred embodiment, the thickener is an acrylic acid (ester) copolymer.

[0024] As a preferred embodiment, the stabilizer includes phenoxyethanol and ethylhexylglycerin, and the weight ratio is (0.4 - 0.5):0.05; preferably, the weight ratio is 0.45:0.05.

[0025] As a preferred embodiment, the aqueous phase includes water, allantoin, glycerin, potassium cocoyl glycinate, disodium cocoyl glutamate, and ethylene glycol distearate.

[0026] As a preferred embodiment, based on the weight percentage of the skin care product: water is supplemented to 100%, allantoin is 0.1 - 0.3%, glycerin is 10 - 20%, potassium cocoyl glycinate is 10 - 20%, disodium cocoyl glutamate is 2 - 3%, and ethylene glycol distearate is 2 - 3%.

[0027] As a preferred embodiment, based on the weight percentage of the skin care product: water is supplemented to 100%, allantoin is 0.1%, glycerin is 20%, potassium cocoyl glycinate is 20%, disodium cocoyl glutamate is 2.5%, and ethylene glycol distearate is 2.5%.

[0028] The third aspect of the present invention provides a preparation method of a skin care product, comprising the following steps:

[0029] S1: Pre - dissolve the raspberry extract and reserve it, pre - dissolve the magnolia bark extract and reserve it.

[0030] S2: Put the aqueous phase into the main pot, stir and heat up to 80 - 85°C, homogenize and disperse and dissolve at 2000 - 2800 rpm, keep stirring for 20 - 40 min while maintaining the temperature, and then start to cool down;

[0031] S3: When the temperature drops to 55 - 60°C, add the pre - mixed cleaning phase, stir evenly, then continue to cool down to 40 - 50°C, add the raspberry extract, magnolia bark extract, and natural active substances, stir evenly, take a sample for testing, and after passing the test, filter and discharge with a 200 - mesh filter cloth.

[0032] Compared with the prior art, the present invention has the following beneficial effects:

[0033] (1) The oil - control composition for whitening and acne - removing of the present invention, by using the combination of raspberry ketone, magnolia bark extract, and natural active substances, can fundamentally improve the problem of excessive sebum secretion of the skin, inhibit inflammation and acne problems of the skin.

[0034] (2) For the oil-control composition for whitening and acne treatment of the present invention, the weight ratio of raspberry ketone, magnolia bark extract and natural active substances is (0.1-1):(1-5):1, which can control oil for a long time, effectively regulate oil secretion, refine pores, prevent acne from growing, and make the skin smoother and more delicate.

[0035] (3) The oil-control composition for whitening and acne treatment of the present invention

[0036] (4) The oil-control composition for whitening and acne treatment of the present invention is applied to external skin cleansing products. The product body is a delicate white paste, with excellent skin feel during use. The addition of the composition will not affect the state stability and foam richness of the product, and it has good applicability.

[0037] (5) The oil-control composition for whitening and acne treatment of the present invention is applied to external skin cleansing products, and has the technical effects of oil control, whitening and brightening. It is highly efficient in acne treatment, has obvious antibacterial effect, and is non-irritating to the skin. Description of the Drawings

[0038] Figure 1 The picture of the state after extrusion of the skin care product prepared in Example 5;

[0039] Figure 2 The picture of the state after extrusion of the skin care product prepared in Comparative Example 8;

[0040] Figure 3 The results of oil red staining of lipid droplets in the in vitro test of the oil control efficacy of the skin care product prepared in Example 5. From top to bottom are Comparative Example 8, negative control, and Example 5. Detailed Description of the Invention

[0041] Examples

[0042] A skin care product includes the above-mentioned oil-control composition for whitening and acne treatment.

[0043] Specifically, it is a facial cleanser. The preparation raw materials are shown in Table 1 below by weight percentage.

[0044] Table 1

[0045]

[0046]

[0047] Note: " / " means not added.

[0048] The acrylic (ester) copolymer is purchased from Guangdong Keyu New Materials Co., Ltd., with the brand KY-SF-1S.

[0049] The raspberry ketone is purchased from Shenzhen Pinyou Biotechnology Co., Ltd.

[0050] The Magnolia officinalis bark extract was purchased from Nanning Houxin Biotechnology Co., Ltd.

[0051] The natural active substance was purchased from TEN in South Korea, with the product number ACZERO.

[0052] A method for preparing a skin care product, comprising the following steps:

[0053] S1: Pre-dissolve the raspberry extract and reserve it, and pre-dissolve the Magnolia officinalis extract and reserve it.

[0054] S2: Put the aqueous phase into the main pot, stir and heat up to 85°C, homogenize and disperse and dissolve at 2500 rpm, keep stirring for 30 min, and start to cool down.

[0055] S3: Cool down to 60°C, add the pre-mixed cleaning phase, stir evenly, then continue to cool down to 45°C, add the raspberry extract, Magnolia officinalis extract, and natural active substance, stir evenly, take a sample for testing, and after passing the test, filter with a 200-mesh filter cloth and discharge.

[0056] The state picture of the skin care product prepared in Example 5 after extrusion can be seen in Figure 1 .

[0057] Comparative example

[0058] A skin care product.

[0059] Specifically, it is a facial cleanser. The preparation raw materials are shown in Table 2 below by weight percentage.

[0060] Table 2

[0061]

[0062]

[0063] Note: " / " means not added.

[0064] The acrylic (ester) copolymer was purchased from Guangdong Keyu New Materials Co., Ltd., with the product number KY-SF-1S.

[0065] The raspberry ketone was purchased from Shenzhen Pinyou Biotechnology Co., Ltd.

[0066] The Magnolia officinalis bark extract was purchased from Nanning Houxin Biotechnology Co., Ltd.

[0067] The natural active substance ACZERO was purchased from TEN in South Korea.

[0068] The tea extract was purchased from Modern Blande Biotechnology (Jiangsu) Co., Ltd., JAPANESE MATCHAEXTRACT.

[0069] The white willow bark extract is purchased from Guangzhou Zhuangyu Biotechnology Co., Ltd., HH052C white willow bark extract.

[0070] The extract of SARGASSUM FUSIFORME is purchased from Guangzhou Zhuangyu Biotechnology Co., Ltd.

[0071] A preparation method of skin care products, comprising the following steps:

[0072] S1: Pre-dissolve the raspberry extract and set aside, pre-dissolve the magnolia bark extract and set aside

[0073] S2: Put the aqueous phase into the main pot, stir and heat up to 85°C, homogenize and disperse and dissolve at 2500 rpm, keep stirring for 30 min, and start to cool down;

[0074] S3: Cool down to 60°C, add the pre-mixed cleaning phase, stir evenly and then continue to cool down to 45°C, add the raspberry extract, magnolia bark extract, and natural active substances, stir evenly and then take samples for testing. After passing the test, filter and discharge with a 200-mesh filter cloth.

[0075] The state picture of the skin care product prepared in Comparative Example 1 after extrusion is shown in Figure 2 .

[0076] Performance test

[0077] 1. Stability test: Place the products of the examples and comparative examples in environments of -15°C, 25°C, 5°C, and 45°C for 14 days, observe the state of the products, and if there is no stratification or discoloration, it is considered qualified. The test results are shown in Table 3.

[0078] Table 3

[0079]

[0080] 2. Evaluation of oil control efficacy: ELISA oil control efficacy detection and evaluation based on inhibiting the activity of 5α-reductase

[0081] Use the "one-step sandwich method" to detect the inhibition rate of the test substance on 5α-reductase. The inhibitory factor (substances that may exist in the sample) acts on 5α-reductase adsorbed on the antibody (the antibody has been fixed in the wells of the microtiter plate), inhibiting its activity. The 5α-reductase remaining on the microplate after treatment is connected to the HRP-labeled immunoenzyme, catalyzing the substrate to develop color, and the absorbance value is measured after terminating the reaction. The blank group (deionized water), the control group (5α-reductase, testosterone), and the positive control group (3 μg / μL of EGCG) are used. By comparing and analyzing the data, the inhibitory effect of the test substance on 5α-reductase is evaluated. And based on this data, the oil control efficacy of cosmetics is scientifically and reasonably evaluated.

[0082] The percentage calculation formula for the sample inhibition rate is as follows: Inhibition rate (%) = 100% × (OD blank + OD control group - OD sample) / (OD control group). The percentage calculation formula for the positive control inhibition rate is as follows: Inhibition rate (%) = 100% × (OD blank + OD control group - OD positive control) / (OD control group). The test results are shown in Table 4.

[0083] Table 4

[0084]

[0085] 3. Patch test

[0086] Dilute the examples and comparative examples with pure water to a concentration of 1 wt%.

[0087] Negative control: Pure water Subjects: A total of 33 people were included, and finally 30 people had valid data, including 26 females and 4 males, aged 20 to 55 years, meeting the volunteer selection criteria for subjects.

[0088] Patch test method: Using the occlusive patch test method, place about 0.020 mL - 0.025 mL (liquid) of the test substance in the patch test device, apply it to the back of the subject with a low-allergenic tape, remove the test substance after 24 hours, observe the skin reaction at 0.5, 24, and 48 hours after removal respectively, and record the results according to the skin reaction grading standard in the currently effective technical specification. The results are shown in Table 5.

[0089] Table 5

[0090]

[0091] 4. Whitening and brightening effect test

[0092] Select a test population with normal and healthy skin and no history of cosmetic allergies, aged 25 - 40 years, a total of 40 people. Samples of the examples and comparative examples, as well as a blank sample, were provided. The blank sample did not contain whitening and anti-acne active ingredients, and the excess part was replaced with deionized water. The above samples and blank samples were divided into 8 groups, with 5 people in each group, and each group tried 2 samples. Before application, clean the face, and after the skin is dried, apply the corresponding product. Each group applied the corresponding product 2 times a day for 4 consecutive weeks. Select the skin detection probe of CK Company in Germany, Mexameter MX18 and Colorimeter CL400, and measure the changes in skin melanin content (MI value) and brightness (L* value) at 0 week before using the product and at 2 and 4 weeks after using the product. The results are shown in Table 5 and Table 6. Among them, the higher the measured value of the MI value, the higher the melanin content. The higher the measured value of the L* value, the higher the skin brightness. The test results are shown in Table 6.

[0093] Table 6

[0094]

[0095] 5. Acne Removal Effect Test

[0096] The test method is the Oxford cup method (agar diffusion method), which is a common method for determining the potency of antibiotics at home and abroad and is also specified in the pharmacopoeias of many countries. Through the inhibition zone test, the inhibitory effect of the test sample on Propionibacterium acnes ATCC11827 is judged.

[0097] Test samples: The products prepared in the examples and comparative examples are diluted with dimethyl sulfoxide (DMSO) to a 5% mass fraction positive control for the following tests.

[0098] Under aseptic operation, pour the sterilized medium into a sterile petri dish with a diameter of 9 cm, so that each petri dish has 15 - 20 mL of medium. After cooling, add 1 mL of Propionibacterium acnes suspension (concentration of 1.0×10 7 CFU / mL), spread the surface of the medium evenly with a spreading rod, place the Oxford cup vertically on the corresponding medium surface with forceps, and gently press it to make it in contact with the medium without gaps. 3 small tubes can be placed on each plate. Drop 0.1 mL of each test sample into each small tube respectively, and make marks without allowing it to overflow. After anaerobic culture of Propionibacterium acnes in a 37°C incubator for 3 days, observe the results.

[0099] During the culture, on the one hand, the test bacteria start to grow, and on the other hand, the test sample diffuses around the Oxford cup as the origin, forming a circular area where colonies cannot grow, that is, the "inhibition zone". The larger the inhibition zone, the better the acne removal effect. The experimental results are judged for antibacterial activity according to the diameter of the inhibition zone. The antibacterial effect judgment criteria are as follows: an inhibition zone diameter > 20 mm is highly effective; an inhibition zone diameter of 15 - 20 mm is moderately effective; an inhibition zone diameter of 10 - 15 mm is lowly effective; an inhibition zone diameter < 10 mm is ineffective. The antibacterial effect is shown in Table 6

[0100] Table 6

[0101] Group Diameter of inhibition zone / mm Acne removal efficacy Example 1 19.6 Moderate effect Example 2 19.8 Moderate effect Example 3 19.4 Moderate effect Example 4 19.1 Moderate effect Example 5 22.3 High effect Example 6 21.6 High effect Example 7 20.8 High effect Example 8 21.3 High effect Comparative example 1 20.3 High effect Comparative example 2 18.6 Moderate effect Comparative example 3 18.4 Moderate effect Comparative example 4 16 Moderate effect Comparative example 5 21.3 High effect Comparative example 6 20.1 High effect Comparative example 7 20.9 High effect Comparative example 8 10.2 Low effect

[0102] 6. In Vitro Test of Oil Control Efficacy: Through QTC-C-LAB-TOP-060 "In Vitro Test Method for Oil Control Efficacy of Cosmetics (Sebaceous Gland Cell Method)".

[0103] 6.1. Cell Seeding: Dilute the cells with cell culture medium to the seeding density and then seed them into a 96-well plate, with a liquid addition volume of 200 μL per well. After the seeding is completed, place it in a CO2 incubator and culture for 24 h ± 2 h.

[0104] 6.2. Administration Treatment: After the cells in the 96-well plate reach an appropriate confluence, perform the drug administration operation according to the experimental grouping in Table 7. Discard the culture medium in the 96-well plate, and add the culture medium containing the test substance to the test substance wells; add normal cell culture medium to the blank control wells, and the liquid addition volume per well is 200 μL. After the drug administration is completed, place the 96-well plate in a CO 2 incubator and culture for 24 h ± 2 h.

[0105] 6.3. Staining: Discard the old liquid in the 96-well plate, wash the wells with buffer solution twice, add 100 μL of fixative to each well to fix the cells; discard the fixative, add oil red solution and stain at 37 °C for 30 min; then discard the oil red solution, add ultrapure water and wash for 5 min; repeat 2 - 3 times.

[0106] 4. Photograph and Observation: Take photos under the microscope and record the staining results, and use image analysis software to calculate the percentage of the stained area "%Area".

[0107] 5. Result Analysis: Use SPSS analysis software, and perform independent sample t-test for data statistical analysis among groups. p < 0.05 indicates statistical difference, denoted by "*"; p > 0.05 indicates no statistical difference.

[0108] Table 7 Experimental Grouping

[0109]

[0110] Test Example 5, lipid droplet synthesis trend graph of Comparative Example 1. The test results are shown in Figure 3 , from top to bottom in the figure are Comparative Example 1, negative control group, and Example 5.

[0111] The negative control group is a mixture of 5α-DHT and linoleic acid, and 5α-DHT is an inducer.

[0112] It can be seen from Figure 3 that compared with Comparative Example 1, the lipid droplet synthesis amount in the negative control group increased significantly, indicating that the inducer stimulation in this experiment was effective.

[0113] Compared with the negative control group, the lipid droplet synthesis amount in Example 5 decreased, with statistical difference (p < 0.05), indicating that Example 5 has the ability to inhibit lipid droplet synthesis at this test concentration, which can be used as evidence to support the oil control effect of this sample.

[0114] Compared with the negative control group, there is not much difference in the lipid droplet synthesis amount in the test sample group of Comparative Example 1, indicating that Comparative Example 1 does not have the ability to inhibit lipid droplet synthesis.

[0115] Conclusion:

[0116] (1) Examples 1-8 have a good effect of inhibiting 5α-reductase on sebum control. Among them, the inhibition rates of Examples 5-8 are generally higher than those of Examples 1-4. Comparative Example 1 also has a good effect of inhibiting 5α-reductase. On the contrary, Comparative Examples 2-4 lack in inhibition rate, and their inhibitory effects are significantly weakened. By comparing Comparative Examples 5-8 with Example 5, it can be seen that Example 5 has a better sebum control effect.

[0117] (2) In the patch test, no adverse reactions were found in Examples 1-8 and Comparative Examples 2-8, while two cases of grade I skin adverse reactions occurred in Comparative Example 1 in the patch test. Examples 1-8 and Comparative Examples 2-8 can better show the effect of being mild and non-irritating.

[0118] (3) After adding the composition in Examples 1-8, the skin melanin decreased significantly and the skin brightening value was relatively high. Among them, Example 5 had a relatively better whitening and brightening effect, while Comparative Examples 1-4 had no whitening and brightening effect. Compared with Example 5, Comparative Examples 5-7 had a slightly inferior brightening effect. It can be seen that Example 5 had an obvious advantage in whitening effect.

[0119] (4) Through Test 4, it can be known that the diameters of the inhibition zones of Examples 5-8 are larger and the acne removal efficacy is better. Among them, the inhibition zone of Example 5 is the largest and the effect is the best. The inhibition zone of Comparative Example 1 is also relatively large and the acne removal efficacy is also relatively good. The inhibition zones of Comparative Examples 2-4 are relatively small and the acne removal ability is low. The overall inhibition zones of Comparative Examples 5-8 are relatively large, but not as good as that of Example 5.

[0120] In summary:

[0121] From the ratios of Examples 1-4 and 5-8, it can be seen that when any one of the three is missing, the sebum control, acne removal, and whitening effects will all decrease. And from Examples 1 and 5, it can be known that when the core active ingredient of Example 1 decreases, its effect also decreases. Thus, it can be seen that Example 5 has better sebum control, acne removal, and whitening effects.

[0122] From Comparative Examples 1-4, it can be known that Comparative Example 1 has better sebum control and acne removal effects. However, through Test 2 of the human patch test, it can be known that when the additive in Comparative Example 1 reaches the effective ratio, it has certain irritation.

[0123] From Comparative Examples 5-8, it can be known that each component of the composition plays different key roles in the effects of sebum control, acne removal, and whitening. When any one of the effective components is replaced, the effect achieved will decrease.

[0124] Regardless of one factor or two factors, it is sufficient to show that the combination ratio of the three active ingredients of the present invention is crucial.

Claims

1. An oil-control composition for whitening and removing acne, characterized in that: The invention comprises raspberry extract, magnolia bark extract and natural active substances; the weight ratio of the raspberry extract, magnolia bark extract and natural active substances is (0.1-1):(1-5):

1.

2. The whitening and acne-removing oil control composition according to claim 1, characterized in that: The raspberry extract includes raspberry ketone and glycolate.

3. The whitening and acne-removing oil control composition according to claim 2, characterized in that: The diol compound is hexylene glycol, and the weight ratio of the raspberry ketone to the diol compound is 0.4:(0.1-0.3).

4. The whitening and acne-removing oil-control composition according to claim 1, characterized in that: The magnolia bark extract comprises magnolia bark extract and butylene glycol, and the weight ratio of the magnolia bark extract to butylene glycol is (0.1-1):

1.

5. The whitening and acne-removing oil-control composition according to claim 4, characterized in that: The purity of magnolol in the Magnolia officinalis bark extract is 95-99%.

6. The whitening and acne-removing oil-control composition according to claim 1, characterized in that: The natural active ingredients include one or a combination of white willow bark extract, tea extract, Centella asiatica extract, Algae extract, Coffea arabica seed extract, Bergamot leaf extract, and Pinus densiflora leaf extract.

7. A skin care product, characterized in that: The invention comprises the whitening and acne-removing oil-control composition according to any one of claims 1 to 6.

8. The skin care product according to claim 7, characterized in that: The preparation raw materials include, by weight percentage, 3-5% of a cleaning phase, 0.3-0.8% of a raspberry extract, 1-3% of a magnolia bark extract, 0.1-1% of natural active substances, 0.1-0.6% of a stabilizer, and the water phase is supplemented to 100%.

9. The skin care product according to claim 8, characterized in that: The cleaning phase includes a thickener, citric acid and sodium chloride, and the weight ratio of the thickener, citric acid and sodium chloride is (1-2): (1.5-2): (1.5-2).

10. A method for preparing the skin care product according to any one of claims 8 to 9, characterized in that: The following steps are involved: S1: Pre-dissolve raspberry extract and magnolia bark extract S2: Add the water phase into the main pot, stir and heat to 80-85°C, homogenize and disperse at 2000-2800rpm, keep warm and stir for 20-40min, and start cooling; S3: Cool down to 55-60℃, add the pre-mixed clean phase, stir evenly, then continue to cool down to 40-50℃, add raspberry extract, magnolia bark extract, and natural active ingredients, stir evenly, take samples for testing, and filter the material with a 200-mesh filter cloth if it is qualified.

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