256results about How to "Non-allergenic" patented technology

The invention discloses mask liquid with multiple skin care effects and a preparation method thereof, aims at providing mask liquid which has effects of skin whitening, speckle removing, wrinkle smoothing, inflammation relieving and diminishing, long-lasting moisturizing and grease balancing, and belongs to the technical field of cosmetics. According to the technical scheme, the mask liquid is prepared from, by weight, 0.5%-3% of sericin, 3.011%-14.02% of a plant extract, 1.11%-8.35% of a moisturizer, 8%-15% of polyalcohol, 0.1%-1.5% of active peptides, 0.08%-0.15% of Carbomer, 0.08%-0.15% of triethanolamine, 0.02%-0.06% of disodium EDTA, 0.3%-0.5% of a preservative and the balance deionized water.

The invention discloses a moisturizing eye mask prepared from bacterial cellulose. The method for preparing a moisturizing eye mask from bacterial cellulose comprises: inoculating 1-2 rings of activated inclined seed Gluconacetobacter xylinum into a medium, and conducting oscillating culture to obtain a seed solution; then inoculating the seed solution into the medium, fully oscillating the bacterial solution obtained by mixing the seed solution and the medium to make them mixed uniformly, then conducting stationary culture, thus generating a bacterial cellulose membrane floating on the solution surface, flushing the generated bacterial cellulose membrane with water to remove the medium and impurities on the membrane surface, then immersing the membrane in an alkali solution to remove thalli and residual medium from the membrane, and finally flushing the membrane with distilled water till the pH value of the membrane is measured up to 7-7.2, thus obtaining a bacterial cellulose wet membrane, which is then cut into an eye mask. The eye mask has the advantages of good moisturizing property and biological tissue compatibility, no toxicity, harmlessness, and simple material processing technology.

The invention relates to a gene recombination human collagen fusion peptide segment. The overall length of the peptide segment comprises 839 amino acids, the nitrogen end of the peptide segment comprises a type III human collagen peptide section of 908-1137, which totally contains 229 amino acids, and the carbon end of the peptide segment comprises a type I human collagen peptide segment of 497-1104, which total contains 608 amino acids, wherein the two peptide segments are connected by using glutamic acid and phenylalanine. The preparation method of the peptide segment comprises the following steps of: constructing cDNAs of clone type I (COL 1) and type III (COL 3) human collagen genes and a Pichia pastoris recombinant expression vector pPOC9K-COL3a1-COL1a1; constructing Pichia pastoris genetic engineering bacteria SMD1168-COL3a10COL1a1 of the gene recombination human collagen fusion peptide segment; preparing the gene recombination human collagen fusion peptide segment, and the like. Proved by tests, the gene recombination human collagen fusion peptide segment prepared by adopting the method can be used as a material for preparing cosmetics.

The externally applied plaster for treating infantile cold type cough is developed on the infantile physiological and pathological characteristics and cough cause and is prepared with 13 kinds of Chinese medicinal materials, including purple perilla, hogfennel root, tangerine peel, eucalyptus leaf, etc. and through decoction, concentration, crushing, mix and other steps. It has the functions of dispelling wind and cold, opening the inhibited lung energy and relieving cough, regulating qi, etc. and is used to treat infantile cough caused by external wind and cold and dyspepsia due to improper feeding, and has obvious curative effect and high safety.

Disclosed is a method for extracting dihydro quercetin from larch. The invention is an improved production method. Due to different production materials and extraction processes, the dihydro quercetin products in U.S. and European markets are very expensive, at a price of 200-1000 euros per gram. Such a high market price economically limits the wide range of practicability of dihydro quercetin products. During the pretreatment of raw materials, 50 kilograms of larch wood chips and 500-800 liters of 50% ethanol solution are added into a reactor to get fully stirred and mixed; then the mixture is extracted and filtered for the second extraction; the filtrates are combined and adsorbed; the organic solvents are collected and dried by a vacuum evaporator through organic phase vacuum distillation; according to a weight proportion of 10:1, the residues are dissolved with hot water, decolorized with activated carbon and then crystallized at a temperature of 3-5 DEG C to precipitate the dihydro quercetin product which is then crushed after vacuum drying to finished product. The invention is used to extract dihydro quercetin from larch.

A process for modifying the lactoprotein by enzyme method features that the immobilized composite enzyme, the ionically regulatory protein structure and heat treating technique are used as selectively hydrolyze the alpha S-casein and beta-lactoglobulin in lactoprotein, resulting in easy digestion and low sensitization. It can be used for composite milk for baby, old man and patient.

The invention discloses a color-protecting and fresh-keeping method for fresh-cut potatoes. The method includes selecting fresh or stored potatoes as the raw material, washing cleanly, peeling, cutting into chips with thicknesses of 0.5-1.0mm, adding a composite color-protecting fresh-keeping solution having the same mass with the potato chips, and soaking for 10-30min at 20 DEG C-30 DEG C; then fishing out the potato chips from the composite color-protecting fresh-keeping solution, washing cleanly with water, soaking in water at 10-150w ultrasonic power and 10-50kHz ultrasonic frequency for 10-30min of ultrasonic time; fishing out the potato chips and draining off, processing for 10-30min under the condition of subzero 0.01MPa-subzero 0.09MPa of vacuum degree; and finally taking the potato chips out of the vacuum environment and soaking immediately into an arbutin solution with the concentration of 0.05-0.3mmol/L, soaking for 5-15min, taking the soaked potato chips out and draining for 1-3min, performing decompression packaging immediately, and storing at an environment of subzero 4 DEG C to zero DEGC. The method adopts ultrasonic and vacuum cooperative processing as well as the Chinese herb extract arbutin as the color-protecting fresh-keeping agent to inhibit enzyme and microbial activities, is better in effect compared with the prior art, and ensures that various potato processed products are prevented from brown stain in a cold storage process for more than 10 days.

The present invention relates to a frozen dry preparation of drug artemisinin derivatives and the preparation method. The present invention is composed of artemisinin derivatives and water-soluble cyclodextrin derivatives, the weight ratio of the artemisinin derivatives and water-soluble cyclodextrin derivatives is 1: 30 to 70, the smashed artemisinin derivatives are added into the water solution of the water-soluble cyclodextrin derivatives at 50 DEG C to 90 DEG C for agitating and dissolving, then the frozen dry preparation is prepared by the conventional process of the injection and the frozen drying. The low-temperature micro-powder technology of the present invention has the advantages that the technology can ensure the physical and chemical properties of the artemisinin derivatives to be consistent before and after the smashing, the process is relatively simple compared with the prior art, the equipments make use of the existing production equipments of the company, thus saving the investment and shorten the production cycle; the dispensing solvent is the water for injection, without the organic solvents, surfactants and cosolvents, so as to improve the safety; the present invention is easy to be dissolved in water, and has fast dissolution speed and the infinite dilution stability, thus avoiding the secondary pollution caused in the other methods which firstly prepare the artemisinin derivatives into the inclusions by using the organic solvents and then sub-package the inclusions thereof.

The invention discloses an external plaster for pediatric deficiency cold and preparation method thereof. Aim at the physiological and pathological characteristics of children and the pathogenic factors and pathogenesis of pediatric deficiency cold, 8 Chinese crude drugs ccontaining white atractylodes rhizome, clove, chinese magnoliaving, nutmeg and so on, is processed by decocting, condensing, crushing, concocting and the other steps to form plaster. The inventive plaster has functions of invigorating qi and yang, supplementing huo and eliminating han. The principle indications are pediatric deficiency cold, sickness, hiccup, diarrhea, cllic, cough, night cry, enuresis, pale complexion, coldness of the body and limbs, tiredness, inappetence, pale lips, whitish tongue and thin white tongue, etc. The external plaster is safe and convenient in use, with remarkable effect. It solves the probleme of fearing the needle and repelling the drugs of the children, furthermore convenient for controling quality and favourable to large-scale industrialization and continuous production.

The present invention discloses a kind of externally applied plaster for treating children's cold type diarrhea and its preparation process. The externally applied plaster is developed based on children's physiological and pathological characteristics and the pathogenesis of cold type diarrhea, and is prepared with ten kinds of Chinese medicinal materials, including atractylodes rhizome, schizonepeta, bupleurum root, etc. and through decoction, concentration, crushing and other steps. It has the functions of invigorating spleen, eliminating wetness, regulating qi, etc. It has obvious curative effect on children's cold type diarrhea, use safety and convenient quality control.

Disclosed are an external plaster for treating children retention syndrome and a preparing method thereof. The plaster is formed by 9 kinds of traditional Chinese medicines, e.g., hovenia dulcis, rhizoma atractylodis, radix bupleuri, etc., with steps of decocting, concentrating, crushing, concocting and the like based on physiological and pathological features of children and etiology and pathogenesis of the children retention syndrome. According to the invention, the prepared external plaster has curative effects of strengthening spleen and improving appetite, promoting digestion and relieving stasis, regulating qi and guiding stagnancy, and moving the bowels, which mainly treats diseases such as no appetite for milk, abdominal fullness and distention, bellyache, emesis, constipation, crying and irritability, reddened tongue, thick or greasy tongue, or fever, dyspneic cough, phlegm(or wheezzing sound), etc., caused by the children retention syndrome. The invention is convenient and safe for using, with remarkable effect and good compliance of children, in addition, the composition facilitates to control the quality thereof and is suitable to industrial scale continuous production.

The invention discloses a traditional Chinese medicine formula with effects of removing freckles and whitening and a preparation method thereof and belongs to the technical field of human health careproducts. The traditional Chinese medicine formula contains the following raw materials: 4-18 parts of ganoderma lucidum, 9-36 parts of tricholoma matsutake, 3-12 parts of ginseng, 1-4 parts of bearberry leaf extract, 3-12 parts of rhizoma polygonati, 3-12 parts of bighead atractylodes rhizome, 1-6 parts of bletilla striata, 3-12 parts of white paeony root, 3-12 parts of ampelopsis japonica, 3-12parts of silkworm larva, 4-12 parts of poria cocos, 1-6 parts of angelica sinensis, 3-9 parts of paeonia lactiflora, 3-12 parts of astragalus, 1-5 parts of almond, 2-10 parts of semen coicis, 1-5 parts of fructus kochiae, 1-5 parts of cortex dictamni, 1-5 parts of liquorice and 2-6 parts of mint. The whitening and freckle removing skin care product provided by the invention is mild and non-irritating, can be applicable to population with sensitive skin, is simple and convenient to use, natural and zero in side effect and has excellent application prospects.

The invention discloses a makeup removing oil, and a preparation method thereof. The makeup removing oil is prepared from, by mass, 20 to 50 parts of tea seed oil, 20 to 35 parts of sweet apricot kernel oil, 10 to 25 parts of grape seed oil, 8 to 25 parts of isohexadecane, 10 to 22 parts of a pure plant emulsifying agent, 0 to 0.5 part of geranium essential oil, and 0.01 to 0.04 part of an antioxidant. Compared with the prior art, the makeup removing oil is an integral whole, is safe and mild via interaction of the ingredients and optimizing of a formula, is capable of removing makeup and dirt, is fresh and cool, is not greasy, is capable of killing bacteria and eliminating inflammation, and repairing skin; the preparation method is simple, and is suitable for industrialized production.

Disclosed is a preparation method for extracting dihydro quercetin from larch. The invention is an improved production method. Due to different production materials and extraction processes, the dihydro quercetin products in U.S. and European markets are very expensive, at a price of 200-1000 euros per gram. Such a high market price economically limits the wide range of practicability of dihydro quercetin products. During the pretreatment of raw materials, 50 kilograms of larch wood chips and 500-800 liters of 50% ethanol solution are added into an extractor to get fully stirred and mixed; then the mixture is extracted and filtered for the second extraction; the filtrates are combined and adsorbed; the organic solvents are collected and dried by a vacuum evaporator through organic phase vacuum distillation; according to a weight proportion of 10:1, the residues are dissolved with hot water, decolorized with activated carbon and then crystallized at a temperature of 3-5 DEG C to precipitate the dihydro quercetin product which is then crushed after vacuum drying to finished product. The invention is used to extract dihydro quercetin from larch.

The invention discloses a levocarnitine for injection and a preparation method thereof. The preparation method comprises the following steps: weighing sodium dihydrogen phosphate and sodium hydroxide, using injection water to dissolve the weighed sodium dihydrogen phosphate and sodium hydroxide and diluting and uniformly mixing, dissolving levocarnitine and mannitol in the buffer solution, addingneedle active carbon and stirring uniformly, stirring for adsorption, and using filtering membrane for filtering and removing carbon; carrying out fine filtration through 0.22 mum microporous membrane, after the intermediate passed the inspection, filling the filtrate with the amount of 5 ml in 15 ml penicillin bottle (using up the liquor in 6 h after degerming), and carrying out half-plug pressing, freeze-drying, capping, visual inspection, labeling, and packaging. According to the invention, buffer salts (the buffer salt ion pair consisting of sodium dihydrogen phosphate and sodium hydroxide) with buffer effect are used in stead of traditional hydrochloric acid to regulate the pH value of the levocarnitine solution, so that the main drug is always in a stable pH environment in the wholepreparation process, and the API degradation caused by violent change of pH value of levocarnitine is avoided. Compared with the similar kind products, the levocarnitine disclosed in the invention has higher effectiveness and higher safety.

The present invention discloses one kind of ewe milk beverage with lactic acid bacteria, and belongs to the field of beverage producing technology. Sour ewe milk as the main material is produced into the ewe milk beverage with lactic acid bacteria through mixing with water, sugar or sweetening agent, fruit juice, stabilizer and other components; filtering; sterilizing; homogenizing and other steps. The ewe milk beverage with lactic acid bacteria is healthful, and the production process is simple and suitable for industrial application.

The invention provides a hydrophilic polyurethane pressure-sensitive adhesive for skins, and a preparation method thereof. The pressure-sensitive adhesive comprises polyurethane, sweetgum resin, alginate, gelatin, fibrous proteins, plant polysaccharides, methacryloylethyl sulfobetaine, triethyl citrate and polyethylene glycol dimethyl ether. The preparation method comprises the following steps: weighing all the above components according to weight parts; mixing polyurethane with sweetgum resin, alginate and gelatin in an open mill, adding the fiber proteins, the plant polysaccharides, methacryloylethyl sulfobetaine, triethyl citrate and polyethylene glycol dimethyl ether, continuously mixing for uniform dispersion, and carrying out hot pressing by using a plate vulcanizing machine to form the pressure-sensitive adhesive with desired thickness. Compared with pressure-sensitive adhesives in the prior art, the acrylic medical pressure-sensitive adhesive prepared in the invention has the advantages of good initial tack, low peel strength, no sensitization, no residue and very strong permanent adhesion.

The invention belongs to the technical field of animal remedy preparation and in particular relates to a pharmaceutical composition for curing dairy cow mastitis and a preparation method and a usage of the pharmaceutical composition. The remedy comes into being by mixing carbomer-940, povidone iodine, hydrocortisone, potash iodate, propylene glycol or glycerol, sodium hydroxide and purified water. The povidone iodine in the preparation has great sterilizing power, no odor or stimulation or sensitization and low toxicity and leads to no residuals which are formed in milk and harmful to human body, no withdrawal period is required during the course of medication, and no milk drinking stop is required; a prepared gel preparation is injected into breasts, a relatively high drug concentration can be achieved in the breasts in a short time, and the treatment cycle is short. Results of clinical trials show that the cure rate of recessive mastitis of the diary cow is up to 86.43 percent, and the effective rate is up to100 percent; and the cure rate of clinical mastitis of the diary cow is up to 78.03 percent, and the effective rate is up to 93.75 percent.

The invention relates to a freckle-removing essence, which is not only capable of slowly fading freckles on faces of people, but also capable of enabling skin on the faces to become beautiful and white slowly. On the basis of A, B, D and E basic formulae, a C raw material is added; and furthermore, the C raw material is composed of ginsenoside extracting solution, pseudo-ginseng extracting solution, licoflavone extracting solution, Chinese angelica extracting solution and lucid ganoderma extracting solution. Compared with the prior art, the freckle-removing essence disclosed by the invention has the advantages as follows: because a strong penetrating agent, namely azone, and an antihistamine reagent, namely sophocarpidine, are used in the formula, the freckle-removing essence prepared by the invention is rapid to take effect and free from irritability; raw materials are convenient to buy and low in price; the production process is simple, therefore, the production cost of the freckle-removing essence is low; no any hormone or other substances hazardous to skin exist in the prescription, so that skin cannot be injured in the use process; and thus, the freckle-removing essence is welcome by the masses of users.