2 results about "Propranolol Hydrochloride" patented technology

The invention discloses a propranolol synthesis method, the purity of a propranolol product obtained by the synthesis method is not less than 99.5%, the content of an impurity B in the product is not more than 0.1%, and after the obtained propranolol and hydrochloric acid are subjected to a salifying reaction, a propranolol hydrochloride finished product with the content of the impurity B not more than 0.05% can be directly obtained without re-purification. Compared with a traditional solvent recrystallization method, the method has the advantages that the intermediate product propranolol is high in purity, high in yield, controllable in quality, suitable for industrial production and the like.

The application relates to the technical field of chemical medicine preparation, and particularly discloses a propranolol hydrochloride drop, a preparation method and application thereof, and the propranolol hydrochloride drop is characterized in that, based on 10ml, the following components are included: an active component carrier 500-520mg, a suspending agent 30-40mg, a sweetening agent 20-25mg, a pH regulator 0.06-0.10mg, essence 3-6mg, and water to 10ml. The propranolol hydrochloride drop provided by the application is accurate in dose, suitable in taste, good in stability and high in safety.