65 results about "P-Aminophenol" patented technology

Disclosed are a resin substrate-based iron oxyhydroxide desulfurizing agent and a preparation method therefor, falling within the technical field of gas purification and treatment. In the present disclosure, sodium percarbonate is used as a raw material to prepare iron oxyhydroxide. Sodium percarbonate serves both as an alkaline precipitant and as an oxidant. P-aminophenol and formaldehyde are subjected to condensation polymerization to form linear phenolic resin, which is then modified with terephthalyl alcohol to connect into a cross-linked network structure resin. The resin is used as a substrate to obtain the resin substrate-based iron oxyhydroxide desulfurizing agent. The preparation method of the present disclosure is simple and achieves a larger sulfur capacity and desulfurization efficiency, making it suitable for the removal of hydrogen sulfide from waste gas.

The invention discloses electronic-grade amine epoxy resin and a preparation method thereof, and belongs to the field of epoxy resin preparation. Aiming at the problems of more by-products and poor performance of the existing epoxy resin preparation, the invention provides the preparation method of the electronic-grade amine epoxy resin, which comprises the following steps: synthesizing a chlorohydrin ether intermediate from p-aminophenol and epichlorohydrin; meanwhile, a catalyst is added in the ring-opening reaction stage; carrying out removal of epoxy chloropropane; alkali metal hydroxide is added for a dehydrochlorination reaction, and a target product is generated in a closed-loop manner; and washing to remove excessive alkali metal hydroxides, and reacting to generate chlorides to obtain the electronic-grade amine epoxy resin. According to the method, the ring opening speed of phenolic hydroxyl is remarkably increased through the catalyst, so that epoxy chloropropane is fully reacted, and residues are reduced; according to the method, excessive epoxy chloropropane is removed, so that side reaction of epoxy chloropropane in a ring closing stage is avoided, generation of by-products is reduced to the greatest extent, operation is simple, and high-quality epoxy resin can be generated.

The invention discloses p-aminophenol polyether polyol, a preparation method of the p-aminophenol polyether polyol, and application of the p-aminophenol polyether polyol in an all-water foaming polyurethane open-cell system. The structure of the p-aminophenol polyether polyol is shown as follows: # imgabs0 # n is 5-10, and m is 1-5. The p-aminophenol polyether polyol contains benzene rings, has good compatibility with high-molecular polyether and a flame retardant TCPP, contains ether bonds, and has good compatibility with water. Meanwhile, the benzene ring structure has certain rigidity, and certain strength can be provided for all-water low-density polyurethane open-cell foam. The p-aminophenol polyether polyol can be used as main polyether of an all-water foaming polyurethane open-cell system, and compared with a traditional all-water foaming polyurethane open-cell system, the p-aminophenol polyether polyol has the advantages of being good in compatibility, high in latitude, high in compression strength, low in cost and the like.

The invention relates to a high-toughness polycarbonate composite material and a preparation method thereof, and belongs to the technical field of polymer materials. The composite material comprises, by weight, 100 parts of modified PC resin, 10-15 parts of ABS resin, 4.5-6.5 parts of oleophilic silica and 0.8-1.1 parts of a processing aid. The modified PC resin is prepared by amine ester exchange of 3-(3,5-di-tert-butyl-4-hydroxyphenyl) methyl propionate and diethanolamine to prepare an intermediate, and then the tertiary amine structure in the intermediate molecule is used to in-situ promote the ring opening of the grafted hydroxyl group and the terminal epoxy silicone oil, and introduce an organic silicon chain, and then the active amino group of p-aminophenol and the residual epoxy are opened, and the phenol structure is introduced for end-capping to prepare a modifier, and finally, the modifier is ester exchanged with bisphenol A and diphenyl carbonate to prepare the modified PC resin, and the composite material with the modified PC resin as a matrix has higher comprehensive strength and toughness performance than the existing PC / ABS material.

The invention relates to the technical field of adhesives, and discloses a preparation method of an epoxy resin adhesive, which comprises the following steps: reacting p-aminophenol with diphenyl dichlorosilane under the catalysis of triethanolamine to obtain di (p-aminophenoxy) diphenyl silane; the preparation method comprises the following steps: carrying out Mannich reaction on amino in di (p-aminophenoxy) diphenyl silane, amino in polyether amine, formaldehyde and phenol to obtain the silane-containing polyether amine type benzoxazine intermediate. And finally, uniformly mixing the silane-containing polyether amine type benzoxazine intermediate and epoxy resin, and curing to obtain the epoxy resin adhesive. The prepared silane-containing polyether amine benzoxazine intermediate contains a silane structure and a benzoxazine structure, both the silane structure and the benzoxazine structure have excellent heat resistance, and the epoxy resin adhesive prepared by adding the silane-containing polyether amine benzoxazine intermediate into epoxy resin has excellent heat resistance.

The invention discloses nearly-spherical silver powder formed by self-assembly of silver nanosheets and a preparation method and application of the nearly-spherical silver powder, and belongs to the technical field of micro-nano material preparation. The preparation method comprises the following steps: firstly, adding a dispersing agent solution into a silver precursor compound solution, stirring, then adding a morphology control agent solution, stirring, and finally adding a reducing agent solution for reaction; and after the reaction is completed, the prepared silver powder is washed and dried, and the nearly-spherical silver powder formed by self-assembly of the silver nanosheets is obtained. The nearly-spherical silver powder is formed through self-assembly of the silver nanosheets, the particle size range of the nearly-spherical silver powder is 0.5-2.0 m, the thickness range of the self-assembled silver nanosheets is 10-50 nm, the overall size is uniform, a large number of stacking faults exist on the surfaces of the silver nanosheets, and the silver nanosheets show an excellent catalytic effect in conversion of p-nitrophenol into p-aminophenol.

The invention discloses a method for synthesizing p-aminophenol through electrolytic reduction, which comprises the following steps: carrying out electrolysis by adopting a diaphragm electrolytic cell and taking an oxidation reaction of hydrogen as an anode reaction, taking a reduction reaction of nitrobenzene as a cathode reaction, taking a sulfuric acid aqueous solution as an anode liquid and taking an aqueous solution containing nitrobenzene and sulfuric acid as a cathode liquid, and recycling an electrolysis product in the cathode liquor to obtain the p-aminophenol. According to the invention, the oxidation reaction of hydrogen is used as the anode reaction, a membrane electrode or a gas diffusion electrode is preferably used as the anode, and an iridium oxide anode and a lead anode are not used, so that the cost is effectively reduced or pollution is avoided; the electrolytic reaction is carried out under the condition that the pressure intensity of the anode chamber is not lower than that of the cathode chamber, the electrolytic voltage is reduced by about 1.6-2.3 V (compared with an iridium oxide anode), the energy consumption is obviously reduced, and the yield of p-aminophenol is improved by about 10%.

The invention discloses a zinc / cobalt-based spinel oxide composite material catalyst as well as a preparation method and application thereof. The zinc / cobalt-based spinel oxide compound catalyst is prepared by taking zinc sulfate, cobalt nitrate and potassium oxalate as metal nodes and ligands through hydrothermal treatment and calcination. The ZnCo2O4 disclosed by the invention is applied to reduction of p-nitrophenol as a high-efficiency catalyst, and under the condition of room temperature, sodium borohydride is used as a reducing agent, and the efficiency of converting p-nitrophenol into p-aminophenol within 4 minutes can reach 100%. The zinc / cobalt-based spinel oxide composite material catalyst is synthesized by adopting a simple and environment-friendly method, the sodium p-borohydride has extremely high catalytic activity in reduction of p-nitrophenol, p-nitrophenol with relatively high toxicity can be reduced into p-aminophenol with relatively low toxicity, and the zinc / cobalt-based spinel oxide composite material catalyst has a potential application prospect in the fields of sewage treatment and the like.

The invention discloses a low-damping PVC-U electrical conduit and a processing technology thereof, and belongs to the technical field of conduit preparation. The low-damping PVC-U electrical conduit is prepared from the following components in parts by weight: 70 to 80 parts of PVC resin, 30 to 42 parts of light calcium carbonate, 8 to 15 parts of ethylene-vinyl acetate copolymer, 0.5 to 1 part of ethylene bis stearamide, 3 to 6 parts of epoxy compound and 4 to 7 parts of compound stabilizer, the preparation method comprises the following steps: preparing an epoxy compound from ethyl benzoylacetate, 2-(trimethylsilyl) phenyl trifluoromethane sulfonate, p-toluenesulfonyl azide, p-aminophenol, p-toluenesulfonyl chloride, iodobenzene diacetic acid and rhodium diacetate as raw materials, and preparing the compound stabilizer from 2-(2-aminoethoxy) ethanol, 4-fluorophenol and xylene alkane diisocyanate as raw materials. The PVC-U electrical conduit prepared from the substances has the advantages of low damping, excellent stability, excellent mechanical property and excellent aging resistance.

The utility model discloses an automatic deslagging device for a catalyst in p-aminophenol production, and particularly relates to the technical field of chemical equipment, the automatic deslagging device comprises a base, the top of the base is fixedly connected with a supporting column, the front side of the supporting column is fixedly connected with two fixing rings, and the interiors of the two fixing rings are fixedly connected with a mixed deslagging mechanism; wherein the mixing deslagging mechanism comprises a mixing barrel, a mixing funnel is fixedly connected to the top of the inner wall of the mixing barrel, a discharging pipe is fixedly connected to the bottom of the mixing funnel, a rear cover is fixedly connected to the top of the mixing barrel, and two movable seats are fixedly connected to the top of the rear cover. By arranging the mixing and deslagging mechanism, the motor drives the rotating rod and the first mixing plate to repeatedly turn over aminophenol and a solid catalyst up and down, so that the aminophenol and the solid catalyst are mixed more sufficiently, and the reaction is more sufficient; meanwhile, aminophenol and a solid catalyst which are subjected to mixed reaction can quickly fall off through a discharging scraper, so that the production efficiency is improved.

The invention discloses a synthesis method of p-aminophenol derivatives, which comprises the following steps: dissolving a compound A in a mixed solvent of acetonitrile and water, cooling to 0-5 DEG C, then adding an organic and inorganic acid catalyst, reacting at room temperature, distilling to remove the solvent, and then adding citric acid to continuously react to obtain a compound B; the initial raw materials are simple and easy to obtain and easy to purchase and store on a large scale, and the synthesized p-aminophenol compound is high in purity and can meet the requirements of most industrial applications on product purity.

The invention discloses a carboxyl-terminated hyperbranched magnetic silver-based catalyst as well as a preparation method and application thereof, and relates to the technical field of wastewater treatment. Comprising the following steps: preparing magnetic Fe3O4 nanoparticles MNP by adopting a coprecipitation method; the preparation method comprises the following steps: sequentially coating the surface of MNP with SiO2 and gamma-aminopropyltrimethoxysilane, and synthesizing an aminated magnetic nanoparticle FSN; the preparation method comprises the following steps: carrying out blending reaction on FSN and a carboxyl-terminated hyperbranched polymer solution, washing, separating a product by a magnet, and drying to obtain carboxyl-terminated hyperbranched magnetic silicon shell particles FSNC; fSNC is dissolved in a silver nitrate solution for reaction, then sodium borohydride is added for continuous reaction, washing, product separation by a magnet and drying are performed, and the carboxyl-terminated hyperbranched magnetic silver-based catalyst Ag / FSNC is obtained. The carboxyl-terminated hyperbranched magnetic silver-based catalyst provided by the invention can effectively catalyze reduction of p-nitrophenol into p-aminophenol, has good magnetic responsiveness, is convenient for recovery and reuse of the catalyst, can continue a catalytic experiment without treatment, and realizes stable recycling of the catalyst.

The present invention belongs to the field of biomedicine, and specifically relates to a sodium pyruvate sustained-release nanoformulation based on pH response, and its preparation method and application. The preparation method of the nanoformulation: under the action of a catalyst, 2,3-dichlorobenzaldehyde, dopamine, and p-aminophenol are added to ethylene glycol dimethyl ether for substitution reaction to obtain compound 1; compound 1 and triethylamine are added to a phosphorus oxychloride solution, and stirred to react to obtain a compound with a phosphate group, an aldehyde group, and a catechol group; polylysine and aldehyde phenylboronic acid are reacted in a PBS buffer solution to obtain aldehyde phenylboronic acid-modified polylysine; sodium pyruvate is added to a solution of a compound with a phosphate group, an aldehyde group, and a catechol group to obtain a mixed solution, the mixed solution is homogenized, and a polylysine solution modified by aldehyde phenylboronic acid is added during the homogenization process, and a mixed solution is obtained after the homogenization is completed, and the mixed solution continues to be stirred and reacted, and the reaction solution is centrifuged, washed, and dried to obtain.

The invention discloses a method for preparing p-aminophenol through nitrobenzene hydrogenation, which comprises the following steps: adding a few-layer graphene coated Ni catalyst, an acid, nitrobenzene and a solvent into a polytetrafluoroethylene lining, ultrasonically mixing uniformly, then putting into a reaction kettle, sealing, replacing air in the reaction kettle with hydrogen, and reacting for 2-4 hours; and raising the temperature to a reaction temperature for reaction to obtain aminophenol. The few-layer graphene coated Ni catalyst is used for catalyzing nitrobenzene hydrogenation to prepare p-aminophenol, the synthesis route of the catalyst is simple, raw materials are cheap and easy to obtain, and compared with a traditional reduction method (such as iron powder reduction), the catalytic hydrogenation route is more environmentally friendly, high in atom utilization rate, easy and convenient to operate and high in economic benefit. The obtained few-layer graphene coated Ni catalyst has the advantages of mild reaction conditions, high product selectivity, easiness in separation and recovery, good cycling stability and the like in catalyzing nitrobenzene hydrogenation to prepare p-aminophenol.

The application discloses an acid-resistant non-noble metal catalyst and a preparation method and application thereof, and particularly relates to the field of acid-resistant metal catalysts, and the preparation method of the acid-resistant non-noble metal catalyst comprises the following steps: step 1, preparation of a carrier; step 2, modification of the carrier; step 3, preparation of an impregnation solution; step 4, preparation of an unactivated catalyst; step 5, activation of the catalyst; and step 6, functionalization of the catalyst. The acid-resistant non-noble metal catalyst prepared by the application can be applied to the synthesis of p-aminophenol from nitrobenzene. The catalyst has good acid resistance and stability, and when applied to the process of preparing p-aminophenol by rearrangement of nitrobenzene hydrogenation, the catalyst has high activity and high selectivity of p-aminophenol under relatively mild reaction conditions, the production conditions are improved, the production cost is reduced, and the product quality is improved.

The invention belongs to the technical field of electrolytic synthesis, and particularly relates to a method for synthesizing p-aminophenol and persulfate. According to the application, a cathode electrocatalytic reduction synthesis process of p-aminophenol and an anode electrocatalytic oxidation synthesis process of persulfate are innovatively coupled, and the cathode current efficiency in the preparation process of p-aminophenol is effectively improved by regulating and controlling anode electrocatalytic temperature parameters. Performance test results show that the cathode current efficiency can reach 81.3%-89.82%, and compared with the cathode current efficiency of 80% or below in a conventional p-aminophenol preparation process, the technical breakthrough exceeding the expectation is achieved, and the unexpected technical effect is shown.

The invention discloses a synthesis method of 4, 4 '-bis (4-aminophenoxy) biphenyl, which comprises the following steps: (1) carrying out salt forming reaction on p-aminophenol and inorganic strong alkali to obtain a suspension containing p-aminophenol salt; the salt forming reaction is carried out in the presence of sodium hydrosulfite; and (2) reacting the p-aminophenol suspension obtained in the step (1) with 4, 4 '-dihalogenated biphenyl to obtain 4, 4'-bis (4-aminophenoxy) biphenyl. The method provided by the invention not only avoids the problem of high production cost caused by the need of a noble metal catalyst for catalytic hydrogenation in the prior art, but also avoids the problems of more three wastes and environmental unfriendliness in the prior art, and has the advantages of low production cost, high safety, environmental friendliness and suitability for industrial mass production.

The present invention relates to a method for preparing a compound of formula (I), where X represents CR23 or N; Y represents CR24 or N; R1 represents H or a COR3 group; R21, R22, R23 and R24 independently represent a hydrogen, a halogen, a nitro group, a cyano group, a CF3 group, a (C1-C6) alkyl group, or a COOH, COR4, COOR5 or CONR6R7 group; R3, R4 and R5 independently represent a (C1-C6) alkyl; and R6 and R7 independently represent a hydrogen or a (C1-C6) alkyl group.

In order to increase the total light transmittance while maintaining a high haze value of the thermoplastic liquid crystal polymer, a thermoplastic liquid crystal polymer molded body is produced with a haze value of 99% or more, a coefficient of thermal expansion of 16 to 27 ppm / °C, and a correlation between the absorption coefficient (ε) and the thickness (x) satisfying ε ≤ 0.21x<supgt;‑0.55< / supgt>. The thermoplastic liquid crystal polymer may be a polyester containing repeating units derived from a substance selected from the group consisting of p-hydroxybenzoic acid and 6-hydroxy-2-naphthoic acid; 6-hydroxy-2-naphthoic acid, terephthalic acid, and p-aminophenol; p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic acid, and terephthalic acid; 6-hydroxy-2-naphthoic acid, terephthalic acid, p-aminophenol, isophthalic acid, hydroquinone, and naphthalenedicarboxylic acid; and p-hydroxybenzoic acid, terephthalic acid, and 4,4'-dihydroxybiphenyl.

The application relates to application of a solid acid catalytic catalyst in preparation of p-aminophenol through nitrobenzene hydrogenation. The application comprises the following steps: adding a solid acid catalyst, cetyltrimethylammonium bromide, deionized water and nitrobenzene into a high-pressure reactor, and reacting under magnetic stirring for 0-24 hours at 25-150 DEG C to obtain the product p-aminophenol. The activated carbon for preparing the solid acid catalyst is coconut shell activated carbon, the series of activated carbon has the advantages of large specific surface area, rich micropores and strong adsorption capacity, and the coconut shell activated carbon solid acid with different acidities is prepared to catalyze the nitrobenzene hydrogenation reaction. The application avoids using traditional liquid acid sulfuric acid to provide the acidic active sites required by the reaction, greatly alleviates the problems of equipment corrosion, environmental unfriendliness, catalyst and product separation difficulty and the like. The catalyst used has good performance, the conversion rate of nitrobenzene is up to 100%, and the yield of p-aminophenol is up to 81.17%.

The present invention provides a preparation method of a phosphorus-containing compound modified imido epoxy resin, comprising the following steps: step 1: reacting phenolphthalein and p-aminophenol to obtain an imido-containing polyphenol compound; step 2: reacting the imido-containing polyphenol compound and epichlorohydrin to obtain an imido-containing multifunctional epoxy resin; step 3: reacting the imido-containing multifunctional epoxy resin with a phosphorus-containing compound to obtain a phosphorus-containing compound modified imido epoxy resin. Imide groups and epoxy groups are gradually introduced into the phosphorus-containing compound, and the generated phosphorus-containing compound modified imido epoxy resin contains more benzene rings and imide structures, thereby improving the heat resistance of the epoxy resin. The N element in the imide group and the P element in the phosphorus-containing compound utilize the N-P synergistic effect to enhance flame retardancy while reducing phosphorus content, thereby reducing the water absorption rate of the resin.

A prepreg having excellent processability and handleability and that can be processed into a cured product with high heat resistance is described along with a method to produce such a prepreg without being restricted by the types and contents of the matrix resin components used, where the prepreg includes at least components [A] to [D] as defined below and a preliminary reaction product that is a reaction product of the component [B] and the component [C]: [A] carbon fiber, [B] epoxy resin comprising a m- or p-aminophenol epoxy resin [b1] and either a glycidyl ether epoxy resin or a glycidyl amine epoxy resin [b2] that has two or more glycidyl groups in a molecule, [C] curing agent, and [D] thermoplastic resin.

The invention discloses a preparation method of an oxygen-containing functional group modified carbon-coated platinum catalyst, the prepared catalyst and application thereof. The preparation method of the catalyst comprises the following steps: (1) weighing a supported platinum catalyst, adding water into the supported platinum catalyst, uniformly mixing, adding a soluble saccharide carbon source compound, stirring to react, heating in a water bath, evaporating to dryness, performing vacuum drying until moisture is dried, and performing high-temperature roasting in an inert protective atmosphere after moisture is removed, thereby obtaining the catalyst. The carbon-coated platinum catalyst is prepared; and (2) dispersing the carbon-coated platinum catalyst in water, adding an oxidant, carrying out stirring reaction, and then carrying out vacuum drying to obtain the oxygen-containing functional group modified carbon-coated platinum catalyst. The invention provides the application of the catalyst in preparation of p-aminophenol through nitrobenzene hydrogenation rearrangement, and high reaction rate and p-aminophenol selectivity can be obtained.

The present invention belongs to the technical field of p-aminophenol preparation, and in particular to a preparation method for preparing p-aminophenol. The following steps are included, after sodium p-nitrophenol is neutralized by acid addition, p-nitrophenol is obtained after cooling and centrifugation, and an antioxidant is added to sodium p-nitrophenol before neutralization; p-nitrophenol is added to the first solvent, and then a catalyst is added, and a hydrogenation reaction is carried out under a hydrogen atmosphere, and the reaction is filtered after the reaction, and the obtained filtrate is placed in a crystallization kettle and the crystallization kettle atmosphere is replaced with a protective gas, and an antioxidant is added, and the temperature is reduced and crystallized, and centrifugation is performed to obtain a crude p-aminophenol; the crude p-aminophenol is added to an antioxidant solution, and after stirring at room temperature, centrifugation, and drying, refined p-aminophenol is obtained. The present invention controls the content of impurities 4,4'-diaminodiphenyl ether in p-aminophenol to less than 0.1%, and the content of impurities 4,4'-diaminodiphenyl ether in p-aminophenol produced in multiple batches is controlled to be stable, and the product qualification rate is high.

The invention belongs to the technical field of acetaminophen medicine synthesis, and particularly relates to a preparation method of acetaminophen, which is characterized in that acetaminophen and glacial acetic acid are subjected to one-step amidation reaction in a negative-pressure low-temperature reaction system to synthesize acetaminophen. The method solves the problems of high acetaminophen preparation temperature, easy raw material oxidation, low crude product quality, high cost and environmental protection potential safety hazard.

The present invention relates to a carbon-based solid acid catalyst and a preparation method and application thereof. The carbon source for preparing the carbon-based solid acid catalyst comes from green, non-toxic and low-cost potato starch, and a series of solid acids with different acidities are prepared to catalyze the hydrogenation reaction of nitrobenzene. It can be applied to the hydrogenation of nitrobenzene to prepare p-aminophenol. The present invention avoids the use of traditional liquid acid sulfuric acid to provide the acidic active sites required for the reaction, greatly alleviating the problems of equipment corrosion, environmental unfriendliness, difficulty in separating the catalyst from the product, etc. The catalyst used has good performance, the conversion rate of nitrobenzene is up to 100%, and the yield of p-aminophenol is up to 67.6%.

The invention relates to the field of epoxy resin, in particular to flame-retardant high-Tg fast-curing epoxy resin for PCM (pulse code modulation) and a preparation method of the flame-retardant high-Tg fast-curing epoxy resin. The raw materials comprise the following components in parts by weight: 100 parts of multifunctional epoxy resin; the polyfunctional epoxy resin is a mixture of p-aminophenol epoxy resin and 4, 4-diaminodiphenylmethane epoxy resin, the glass transition temperature of the polyfunctional epoxy resin is 240-250 DEG C, and the epoxy equivalent is 100-125; 5 to 10 parts of a PES toughening agent; 15 to 20 parts of a flame retardant; 0.3 to 0.5 part of fumed silica; 5.5 to 7 parts of a dicyandiamide curing agent; and 1.5-3 parts of a urea accelerator. The epoxy resin prepared by the preparation method disclosed by the invention not only has relatively high glass transition temperature, but also has good mechanical properties, toughness and flame retardance and is short in curing time; meanwhile, the preparation raw materials are easy to obtain, and the process is simple.

A porous material is used as a working electrode, a hydrophobic layer of the working electrode faces a raw material solution containing nitrobenzene, and a reaction layer of the working electrode is electrolyzed by a sulfuric acid aqueous solution to synthesize p-aminophenol. According to the method, a surface active agent and nitrobenzene do not need to be added into the electrolyte, a p-aminophenol solution with the high concentration is synthesized, the separation and purification steps of the product are optimized, compared with a traditional method, the concentration of a sulfuric acid aqueous solution used in the traditional method is reduced to 10% from 20%, meanwhile, the reaction voltage is also reduced by 0.4 V, and the method is suitable for industrial production. The production cost and the energy consumption are reduced, the environmental pollution is reduced, and the current efficiency is improved by nearly 25% and the selectivity is improved by 10%.

The invention discloses a graphite film-p-aminophenol-copper composite material and a preparation method thereof, and belongs to the field of metal-based composite material thermal management, and the composite material is structurally characterized in that phenol molecules are introduced to the upper and lower surfaces of a flake graphite film,-OH in phenol and copper ions are coordinated, and the graphite film-p-aminophenol-copper composite material is prepared. The preparation method of the copper-graphite film-copper composite material comprises the following steps: treating the surface of the flaky graphite film, putting the flaky graphite film into absolute ethyl alcohol containing p-aminophenol, magnetically stirring under the protection of nitrogen, adding isoamyl nitrite, magnetically stirring, and reacting at a constant temperature, so as to obtain the copper-graphite film-copper composite material. Taking out the flake graphite film, washing and drying in vacuum; and the dried flake graphite film is electroplated with copper, and the obtained graphite film-p-aminophenol-copper composite material is good in in-plane thermal conductivity and good in bending performance.

The invention provides a biosensor, a nucleic acid detection and typing system based on a CRISPR system, a detection method and application, and belongs to the technical field of biological detection, alkaline phosphatase is adopted for catalyzing hydrolysis of p-aminophenyl phosphate to obtain p-aminophenol, the p-aminophenol is used for reducing silver ions, metal silver is deposited on the surfaces of gold nanoparticles, and the gold nanoparticles can be used for detecting the nucleic acid. Compared with a traditional Cas12a detection method combining ALP mediated p-nitrophenyl phosphate hydrolysis, the CRISPR / Cas12a biosensing strategy combining ALP has the advantages that the sensitivity is improved by 10,000 times, target DNA can be detected through naked eyes, the detection limit is as low as 300 aM, and the potential of no instrument application is shown.