44 results about "Furanocoumarin" patented technology

The present invention provides compositions of bakuchiol (UP246) having low levels of impurities, particularly furanocoumarin impurities. The present invention further provides improved methods for the isolation, purification and analysis of compositions of bakuchiol. Finally, the present invention provides methods for using the purified bakuchiol compositions and formulations thereof for the prevention and treatment of various diseases and conditions mediated by cyclooxygenase (COX), lipoxygenase (LOX), minor inflammatory conditions and various microbial infections. The methods of this invention are comprised of administering to a host in need thereof an effective amount of the composition of this invention together with a pharmaceutically acceptable carrier.

The invention relates to a site-directed mutagenesis modified saccharomyces cerevisiae dipeptidyl peptidase III. The site-directed mutagenesis modified saccharomyces cerevisiae dipeptidyl peptidase III is characterized in that the site-directed mutagenesis modified saccharomyces cerevisiae dipeptidyl peptidase III is a mutant generated by substitution of multiple amino acids in saccharomyces cerevisiae dipeptidyl peptidase III derived from saccharomyces cerevisiae S288c and having an amino acid sequence being SEQ ID NO.1, substitution of the multiple amino acids refers to substitution of a 570th site, a 572th site and a 574th site, and the site-directed mutagenesis modified saccharomyces cerevisiae dipeptidyl peptidase III is modified into an enzyme with an oxygenolysis effect on 6-methoxy di-furocoumarin. The site-directed mutagenesis modified saccharomyces cerevisiae dipeptidyl peptidase III can be applied to preparation of products for removing the 6-methoxy di-furocoumarin from feedstuffs, additives of the feedstuffs, foods and additives of the foods and can be further applied to preparation of medicines for preventing diseases induced by the 6-methoxy di-furocoumarin.

The invention relates to a furocoumarin compound and application thereof, in particular to a novel furocoumarin compound shown as a general formula I and application thereof serving as an active ingredient to the preparation of a medicament for treating or preventing diseases relevant to bacterial infection, in particular to the application of the novel furocoumarin compound serving as the activeingredient to the preparation of a medicament for treating or preventing diseases caused by or mediated by helicobacter pylori.

The present disclosure relates generally to systems and methods for the photo- inactivation of microorganisms. More specifically, the present invention is directed towards the photo-inactivation of microorganisms, such as viruses, using at least one furanocoumarin and broad spectrum pulsed light. For example, an aspect of the present invention includes a method for inactivating a herpesvirus, such as herpes B virus or herpes virus papio 2 using a psoralen and broad spectrum pulsed light.

The invention discloses a preparation method of a photoactive benzofuranocoumarin compound. The photoactive benzofuranocoumarin compound is the compound shown in formula I; the enantioselectivity of the compound shown in formula I is as high as 95-99%. The photoactive benzofuranocoumarin skeleton of the present invention contains two chiral centers, adopts a 1,4-addition reaction strategy, uses a common and easily available chiral base as a catalyst, and uses 3-acylcoumarins of different structures, Benzofuranimine is used as a substrate to synthesize a photoactive benzofuranocoumarin compound containing two chiral centers; this method has low raw material prices, simple operation, low equipment requirements, environmental friendliness, and operator Safety, mild reaction conditions, high yield, high enantioselectivity, wide range of substrates, and great industrialization potential.

The present invention discloses uses of a natural angular furan coumarin compound Cniforin B as an agricultural bactericide. The compound Cniforin B is used for controlling agricultural fungal diseases as a bactericide, and can effectively control crop diseases such as rape sclerotinia, strawberry gray mold, wheat scab, pepper anthracnose and tomato early blight. The agricultural bactericide made by using the natural compound Cniforin B as the active ingredient has the characteristics of good controlling effect, broad spectrum, low toxicity, no residues, no contaminants and no public nuisance, and is particularly beneficial to environmental protection.