The present invention provides an oral drug special for treatment of drunkenness syndrome, wherein the oral drug has characteristics of good therapy effect, safety and reliability, and no side effect. The oral drug of the present invention has the following characteristics that: lobed kudzuvine root, villous amonmum fruit, raosin tree seed, combined spicebush root, angelica, lucid ganoderma, purslane and lotus leaf are adopted as sovereign drugs; dried plum, mulberry, bamboo shavings, dolichos lablab, lightyellow sophora root, lesser galangal rhizome, climbed clubmoss herb and prepared commonmonkshood daughter root are adopted as minister drugs; with lobed kudzuvine flower bud, wild dendranthema flower, jasmine, lanatehead saussurea herb, subshrubby peony flower, lily, mangnolia and safflower, effects of yin nourishing, dryness moisturizing, fluid production promoting, thirst quenching, and vigour reinforcing are provided, the stomach discomfort is relieved, the thick drug taste after mixing the traditional Chinese drugs is adjusted, and the fragrant taste is increased; pear, sugar cane, yacon, bengal waterdropwort herb, pomelo, water chestnut, apple, carrot, honey and yeast provide effects of qi benefiting, blood controlling, heart benefiting, lung astringing, dampness eliminating, vomiting stopping, qi depression relieving and stagnation eliminating, dryness moisturizing and intestinal tract lubricating, and are adjuvant drugs; with combination of the drugs in the formula, effects of qi benefiting, yin nourishing, liver protecting, nerve calming, palpitation stabilizing, qi regulating, vomiting stopping, spleen and stomach strengthening, and heart enhancing are provided.