The invention discloses a PDRN-containing whitening and
freckle-removing composition. The whitening and
freckle-removing composition is prepared from PDRN, nonapeptide, pentapeptide,
hyaluronic acid and
nicotinamide. The PDRN-containing whitening and
freckle-removing composition is prepared from the following components in parts by weight: 0.05 to 5 parts of PDRN, 0.05 to 0.5 part of nonapeptide, 0.001 to 0.5 part of pentapeptide and 0.1 to 7 parts of
nicotinamide. The invention also discloses application of the whitening and freckle-removing composition in
cosmetics. The composition and the cosmetic containing the composition have a synergistic effect, can inhibit the formation of
melanin from multiple angles, activate the activity of aged cells, promote the synthesis of collagen and
elastin, reconstruct and repair an epidermis defense function, improve a
skin cell microenvironment, increase the
water content of
skin, improve the elasticity and smoothness of the
skin, and reduce the generation of
inflammatory factors. Therefore, the problems of
dryness, roughness, looseness, fine lines,
darkness and the like of the skin are solved in all angles.