Mixture containing microcapsules, preparation method of mixture and nursing pad

Abstract

The invention provides a mixture containing microcapsules, a preparation method of the mixture and a nursing pad, and belongs to the technical field of medical monitoring nursing materials. Methyl red and bromothymol blue in the microcapsule-containing mixture provided by the invention are acid-base indicators, so that the nursing pad has a pH value indication effect; the persimmon extract has antibacterial and deodorizing effects; the polyhexamethylene guanidine has a broad-spectrum antibacterial effect; the polyethylene glycol has good solubility, lubricity, moisture retention and the like, so that the solubility, the stability and the bioavailability of the raw materials are improved; part of substances (methyl red, bromothymol blue, persimmon extract, polyhexamethylene guanidine and polyethylene glycol) in the raw materials can be contained in hydrophobic cavities of cyclodextrine to form a microcapsule structure, so that the stability and dispersity of the raw materials are improved, slow and continuous release is realized, the nursing pad has long-time antibacterial and deodorant effects, and the service life of the nursing pad is prolonged. And the color developing uniformity of the nursing pad can be improved.

Description

Technical Field

[0001] The invention belongs to the technical field of medical monitoring and nursing products, and particularly relates to a mixture containing microcapsules, a preparation method thereof, and a nursing pad. Background Art

[0002] Nursing pads are a common medical product in the healthcare field, widely used in bedridden care, incontinence care, and rehabilitation care. They typically consist of a leak-proof base film, an absorbent core, and a top layer, with the absorbent core positioned between the two. When used, the pad is placed flat on the patient's buttocks and below. It quickly absorbs urine and other excreta, preventing contamination of bedding and clothing, keeping the body and surrounding area clean, and providing comfortable and hygienic care. However, long-term clinical nursing practice has revealed that traditional medical nursing pads offer unsatisfactory antibacterial and deodorizing properties. Furthermore, bedridden patients require regular health checkups, with urinalysis being a common test item. Urine pH can reflect the patient's acid-base balance and aid in disease diagnosis, monitoring the effectiveness of medications, assessing urinary tract diseases, and assessing dietary adequacy. The mobility difficulties of bedridden patients make travel and checkups difficult.

[0003] Therefore, how to provide an absorbent core material so that the nursing pad has a pH value indication function and excellent antibacterial and deodorizing functions is a technical problem that needs to be solved urgently in this field. Summary of the Invention

[0004] The present invention provides a mixture containing microcapsules, a method for preparing the mixture, and a nursing pad. When used in a nursing pad, the microcapsule-containing mixture can provide the pad with a pH indicator, displaying different colors under different pH conditions, and exhibiting enhanced antibacterial and deodorizing effects.

[0005] In order to achieve the above-mentioned object of the invention, the present invention provides the following technical solutions:

[0006] The present invention provides a mixture containing microcapsules, which is prepared by including the following raw materials in percentage by mass:

[0007] Methyl red 0.05%-0.1%, bromothymol blue 0.25%-0.5%, persimmon extract 1%-5%, polyhexamethyleneguanidine aqueous solution 1%-3%, polyethylene glycol 0.5%-1.5%, cyclodextrin 36.9%-52.2%, super absorbent resin 25%-28% and water 20%-25%.

[0008] Preferably, the super absorbent resin is sodium polyacrylate; the mesh size of the sodium polyacrylate is ≥100 mesh.

[0009] Preferably, the polyethylene glycol is polyethylene glycol 4000.

[0010] Preferably, the mesh size of the methyl red is ≥500 mesh.

[0011] Preferably, the mesh size of the bromothymol blue is ≥500 mesh.

[0012] The present invention also provides a method for preparing the mixture containing microcapsules described in the above technical solution, comprising the following steps:

[0013] (1) mixing a persimmon extract, a polyhexamethyleneguanidine aqueous solution, polyethylene glycol, and water to obtain a mixed solution;

[0014] (2) Methyl red, bromothymol blue, cyclodextrin and the mixed solution obtained in step (1) are mixed and dried, and then a super absorbent resin is added to obtain a mixture containing microcapsules.

[0015] The present invention also provides a nursing pad, comprising a hot air non-woven fabric, an absorbent core and a leak-proof bottom film arranged in sequence from top to bottom;

[0016] The absorbent core includes a first absorbent sanitary paper layer, a fluff pulp layer and a second absorbent sanitary paper layer arranged in sequence from top to bottom; a mixture containing microcapsules is contained between the first absorbent sanitary paper layer and the fluff pulp layer; the mixture containing microcapsules is the mixture containing microcapsules described in the above technical solution or the mixture containing microcapsules prepared by the preparation method described in the above technical solution.

[0017] Preferably, in the absorbent core, the mass ratio of the mixture containing microcapsules to the area of the fluff pulp layer is 0.0018 to 0.0022 g / cm 2 .

[0018] Preferably, the thickness of the hot air non-woven fabric is 0.3 to 0.5 mm.

[0019] Preferably, the thickness of the leak-proof bottom film is 0.02 to 0.03 mm.

[0020] The invention provides a mixture containing microcapsules, which is prepared from the following raw materials, calculated by mass percentage: 0.05% to 0.1% of methyl red, 0.25% to 0.5% of bromothymol blue, 1% to 5% of persimmon extract, 1% to 3% of polyhexamethyleneguanidine aqueous solution, 0.5% to 1.5% of polyethylene glycol, 36.9% to 52.2% of cyclodextrin, 25% to 28% of super absorbent resin and 20% to 25% of water. The methyl red in the mixture containing microcapsules provided by the present invention is an acid-base indicator, which is red when the pH value is ≤4.4, yellow when the pH value is ≥6.2, and orange when the pH value is between 4.4 and 6.2. Bromothymol blue is an acid-base indicator, which is yellow when the pH value is ≤6.0, and changes from yellow to light green when the pH value is 6.0-6.7, with the color being mainly yellow-green. When the pH value is between 6.7 and 7.5, the light green color gradually darkens to green, and when the pH value is ≥7.6, it gradually turns blue and the color darkens, thereby making the nursing pad have a pH indicator function and display different colors under different pH conditions; persimmon extract has both antibacterial and deodorizing effects; polyhexamethylene guanidine has a broad-spectrum antibacterial effect on Gram-negative bacteria, Gram-positive bacteria, fungi and molds; polyethylene glycol has good solubility, lubricity and moisturizing It has properties such as solubility and bioavailability, and can be used as a dispersant to improve the solubility and bioavailability of each raw material. At the same time, polyethylene glycol is not easily affected by external environments such as oxidation, light and high temperature, has good stability and controllability, can maintain the stability of the mixture containing microcapsules, and extend the shelf life; cyclodextrin has the characteristics of external hydrophilicity and internal hydrophobicity. Some substances in the raw materials (methyl red, bromothymol blue, persimmon extract, polyhexamethylene guanidine and polyethylene glycol) can be contained in the hydrophobic cavity of cyclodextrin to form a microcapsule structure, forming a protective effect, improving the stability and dispersibility of the raw materials, and realizing slow and continuous release, so that the nursing pad has a long-term antibacterial and deodorizing effect, and can improve the color uniformity of the nursing pad; super absorbent resin has excellent water absorption and water retention properties, which can make the nursing pad have excellent ability to absorb pollutants such as urine. The results of the examples show that when the mixture containing microcapsules provided by the present invention is used for the absorbent core of a nursing pad, the deodorization rate of NH3 and H2S is above 98%, and the antibacterial rate against Staphylococcus aureus, Escherichia coli and Candida albicans is above 96%. After being placed in a constant temperature box at 37-40°C for 3 months, the antibacterial rate against Staphylococcus aureus, Escherichia coli and Candida albicans is still above 96%. The color appears dark red at a pH of 2.0, red at a pH of 4.0, orange at a pH of 5.0, yellow at a pH of 6.0, light green at a pH of 7.0, blue-green at a pH of 8.0, blue at a pH of 9.18, and dark blue at a pH of 11.0. DETAILED DESCRIPTION

[0021] The present invention provides a mixture containing microcapsules, which is prepared by including the following raw materials in percentage by mass:

[0022] Methyl red 0.05%-0.1%, bromothymol blue 0.25%-0.5%, persimmon extract 1%-5%, polyhexamethyleneguanidine aqueous solution 1%-3%, polyethylene glycol 0.5%-1.5%, cyclodextrin 36.9%-52.2%, super absorbent resin 25%-28% and water 20%-25%.

[0023] The raw materials used to prepare the microcapsule-containing mixture of the present invention include 0.05% to 0.1% methyl red by mass. In one embodiment, the methyl red mass percentage can be 0.05%, 0.06%, 0.07%, 0.08%, 0.09%, or 0.1%. By controlling the amount of methyl red within this range, the present invention can further improve the color rendering and color uniformity of the nursing pad.

[0024] In the present invention, the mesh number of described methyl red is preferably ≥500 mesh. In the present invention, when the mesh number of methyl red is not within the above-mentioned scope, the present invention preferably pulverizes methyl red. The present invention has no particular restrictions on the operation of described pulverization, and adopts the technical solution of pulverization well known to those skilled in the art to ensure that the mesh number of methyl red after pulverization is within the above-mentioned scope. In an embodiment of the present invention, adopt supersonic airflow mill that methyl red is pulverized.

[0025] In the present invention, the methyl red is an acid-base indicator that changes color over a pH range of 4.4 to 6.2, exhibiting an orange color when the pH is between 4.4 and 6.2, a red color when the pH is ≤ 4.4, and a yellow color when the pH is ≥ 6.2. The present invention does not particularly limit the source of the methyl red; commercially available products known to those skilled in the art may be used.

[0026] The raw materials used to prepare the microcapsule-containing mixture of the present invention also include 0.25% to 0.5% bromothymol blue, calculated by mass percentage. In one embodiment, the mass percentage of bromothymol blue can be 0.25%, 0.3%, 0.35%, 0.4%, 0.45%, or 0.5%. By controlling the amount of bromothymol blue within the above range, the present invention can further improve the color rendering effect and color uniformity of the nursing pad.

[0027] In the present invention, the mesh size of the bromothymol blue is preferably ≥500 mesh. In the present invention, when the mesh size of the bromothymol blue is not within the above range, the present invention preferably pulverizes the bromothymol blue. The present invention does not specifically limit the pulverization operation; a pulverization technique well known to those skilled in the art can be employed to ensure that the mesh size of the bromothymol blue after pulverization is within the above range. In an embodiment of the present invention, the bromothymol blue is pulverized using a supersonic jet mill.

[0028] In the present invention, the bromothymol blue is a acid-base indicator with a color change range of 6.0 to 7.6. When the pH value is ≤ 6.0, it is yellow. When the pH value is 6.0 to 6.7, the color changes from yellow to light green, with yellow-green as the main color. When the pH value is 6.7 to 7.5, the light green color gradually darkens to green. When the pH value is ≥ 7.6, it gradually turns blue and the color becomes darker. The present invention does not specifically limit the source of the bromothymol blue, and commercially available products familiar to those skilled in the art can be used.

[0029] The present invention adds methyl red and bromothymol blue, so that the nursing pad containing the mixture of microcapsules has a pH value indication function and displays different colors under different pH conditions.

[0030] The raw materials used to prepare the microcapsule-containing mixture of the present invention also include 1% to 5% persimmon extract by weight. In one embodiment, the persimmon extract can be 1%, 2%, 3%, 4%, or 5% by weight. By controlling the amount of persimmon extract within the aforementioned range, the present invention can further enhance the antibacterial and deodorizing effects of the microcapsule-containing mixture and the nursing pad.

[0031] The persimmon extract described herein is preferably obtained from the fruit of the persimmon tree, Diospyros kaki Thunberg (Ebenaceae). Persimmon tannin, the primary component of the persimmon extract, possesses both antibacterial and deodorizing properties, exhibiting excellent deodorizing effects against sulfides, nitrogen compounds, methyl mercaptan, and the like. In the present invention, the persimmon extract is preferably food grade. The source of the persimmon extract is not particularly limited; commercially available products known to those skilled in the art may be used.

[0032] The raw materials used to prepare the microcapsule-containing mixture of the present invention also include, by mass percentage, a 1% to 3% aqueous polyhexamethyleneguanidine solution. In one embodiment, the mass percentage of the polyhexamethyleneguanidine solution can be 1%, 1.5%, 2%, 2.5%, or 3%. By controlling the amount of the polyhexamethyleneguanidine solution within the aforementioned range, the present invention can further enhance the antibacterial efficacy of the microcapsule-containing mixture and the nursing pad.

[0033] The polyhexamethyleneguanidine aqueous solution of the present invention has a broad-spectrum antibacterial effect against Gram-positive bacteria, Gram-negative bacteria, fungi, molds, etc., is non-volatile, non-decomposable, safe and non-irritating. In addition, polyhexamethyleneguanidine has good compatibility with superabsorbent resin and is not affected by the hot pressing process during the preparation of the nursing pad, thereby making the nursing pad have excellent antibacterial effect.

[0034] In the present invention, the mass content of polyhexamethyleneguanidine in the polyhexamethyleneguanidine aqueous solution is preferably 10-30%, more preferably 20%. The present invention has no particular limitation on the source of the polyhexamethyleneguanidine aqueous solution, and commercially available products known to those skilled in the art can be used.

[0035] The raw materials for preparing the microcapsule-containing mixture of the present invention further include 0.5% to 1.5% polyethylene glycol by mass. As an embodiment, the mass percentage of the polyethylene glycol can be specifically 0.5%, 0.8%, 1.0%, 1.2% or 1.5%.

[0036] In the present invention, the polyethylene glycol is preferably polyethylene glycol 4000. In the present invention, the polyethylene glycol has the characteristics of good solubility, lubricity and moisturizing properties, and can be used as a dispersant to improve the solubility and bioavailability of each raw material. At the same time, the polyethylene glycol is not easily affected by external environments such as oxidation, light and high temperature, has good stability and controllability, can maintain the stability of the mixture containing microcapsules, and extend the shelf life. The present invention limits the amount and type of polyethylene glycol to the above range, which can make it have better solubility and other properties, further improve the solubility and other properties of each raw material, thereby improving the various properties of the mixture containing microcapsules and the nursing pad. The present invention does not specifically limit the source of the polyethylene glycol, and commercially available products familiar to those skilled in the art can be used.

[0037] The raw materials for preparing the microcapsule-containing mixture of the present invention further include 36.9% to 52.2% cyclodextrin by mass. In one embodiment, the cyclodextrin by mass percentage can be 36.9%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%, 49%, 50%, 51%, 52%, or 52.2%.

[0038] Cyclodextrin has the properties of being hydrophilic on the outside and hydrophobic on the inside. Water-insoluble substances are typically hydrophobic and can be encapsulated by the hydrophobic cavities of cyclodextrin, forming a microcapsule structure. This allows the originally water-insoluble substances to be encapsulated within the cyclodextrin, thereby improving their dispersibility in water to a certain extent. The addition of cyclodextrin in the present invention allows methyl red, bromothymol blue, persimmon extract, polyhexamethylene guanidine, and polyethylene glycol to enter the cyclodextrin cavities, creating a protective effect and improving the stability, dispersibility, and release rate of each raw material, achieving a slow, sustained release. When used in a nursing pad, the pad has a long-lasting antibacterial and deodorizing effect and can improve the color uniformity of the nursing pad. By controlling the amount of cyclodextrin used in the present invention within the above range, the antibacterial and deodorizing effects and duration of the nursing pad can be further enhanced, as well as the display uniformity. The present invention does not specifically limit the source of the cyclodextrin; commercially available products familiar to those skilled in the art can be used.

[0039] The raw materials for preparing the microcapsule-containing mixture of the present invention further comprise 25% to 28% by mass of a super absorbent resin. As an embodiment, the super absorbent resin can be 25%, 26%, 27% or 28% by mass.

[0040] In the present invention, the water absorption ratio of the super absorbent resin (0.9 wt% saline) is preferably ≥50 times; the water absorption speed of the super absorbent resin is preferably ≤5 seconds (10 g super absorbent resin absorbs 300 g, 0.9 wt% saline).

[0041] In the present invention, the super absorbent resin is preferably sodium polyacrylate; the mesh size of the sodium polyacrylate is preferably ≥100 mesh.

[0042] The superabsorbent resin described in the present invention is a functional polymer material with a three-dimensional cross-linked network structure and containing a large number of hydrophilic groups. It has a high water absorption function, absorbing water hundreds to thousands of times its own weight, and has excellent water retention properties. Once it absorbs water and expands to form a hydrogel, it is difficult to separate the water even under pressure. The addition of the superabsorbent resin in the present invention can make the mixture containing the microcapsules have excellent water absorption and water retention properties, thereby making the nursing pad have excellent ability to absorb pollutants such as urine. When the present invention controls parameters such as the amount of superabsorbent resin within the above-mentioned range, the ability of the nursing pad to absorb liquid pollutants can be further improved. The present invention does not specifically limit the source of the superabsorbent resin, and commercially available products familiar to those skilled in the art can be used.

[0043] The raw materials for preparing the microcapsule-containing mixture of the present invention further include 20% to 25% water by mass. As an embodiment, the mass percentage of the water can be specifically 20%, 21%, 22%, 23%, 24% or 25%.

[0044] In the present invention, the water is preferably deionized water; the pH value of the deionized water is preferably 5.5 to 6.5, more preferably 6.0. Water is added to dissolve or disperse other raw materials. Weakly acidic water of the aforementioned pH value is added to adjust the pH of the mixture containing the microcapsules, facilitating subsequent color development.

[0045] The raw materials for preparing the mixture containing microcapsules of the present invention are added with methyl red and bromothymol blue, so that when the mixture containing microcapsules is used in a nursing pad, the nursing pad can realize a visual color reaction to the pH value of urine, and the user's health status and dietary balance can be monitored through color display; the addition of persimmon extract and polyhexamethylene guanidine makes the nursing pad have antibacterial and deodorizing effects, has excellent antibacterial effects on Staphylococcus aureus, Escherichia coli, and Candida albicans, has excellent removal effects on major odor components such as ammonia and hydrogen sulfide in urine, can effectively inhibit the growth of bacteria after the super absorbent resin absorbs liquid pollutants, improves the safety of the nursing pad, and more effectively protects the user's sanitary environment; cyclodextrin is added to coat and protect the components such as methyl red, bromothymol blue, persimmon extract and polyhexamethylene guanidine, improves stability, improves dispersibility, controls release, and realizes slow and sustained release, so that the antibacterial and deodorizing effects can be effectively released when used in the nursing pad, and the effective time can be up to more than 2 years.

[0046] The present invention also provides a method for preparing the mixture containing microcapsules described in the above technical solution, comprising the following steps:

[0047] (1) mixing a persimmon extract, a polyhexamethyleneguanidine aqueous solution, polyethylene glycol, and water to obtain a mixed solution;

[0048] (2) Methyl red, bromothymol blue, cyclodextrin and the mixed solution obtained in step (1) are mixed and dried, and then a super absorbent resin is added to obtain a mixture containing microcapsules.

[0049] The invention mixes persimmon extract, polyhexamethyleneguanidine aqueous solution, polyethylene glycol and water to obtain a mixed solution.

[0050] The present invention has no particular limitation on the mixing operation of the persimmon extract, polyhexamethyleneguanidine aqueous solution, polyethylene glycol and water. The raw materials can be uniformly mixed using a material mixing technique well known to those skilled in the art.

[0051] After obtaining the mixed solution, the present invention mixes methyl red, bromothymol blue, cyclodextrin and the mixed solution, then dries the mixture, and then adds a highly absorbent resin to obtain a mixture containing microcapsules.

[0052] In the present invention, the mixing of methyl red, bromothymol blue, cyclodextrin and the mixed solution is preferably grinding. In the present invention, during the grinding process, methyl red, bromothymol blue, persimmon extract, polyhexamethyleneguanidine aqueous solution and polyethylene glycol enter the cavity of cyclodextrin.

[0053] In the present invention, the grinding time is preferably 25 to 35 minutes, more preferably 30 minutes. The present invention controls the grinding time within the above range. Too short a grinding time may result in uneven mixing of cyclodextrin with other raw materials, incomplete inclusion reaction, and affect the embedding property and stability of the microcapsules. Too long a grinding time may destroy the structure of the already formed inclusion compound, increasing energy consumption and production costs.

[0054] The present invention has no particular limitation on the drying operation, and drying to a constant weight may be performed using a drying technique well known to those skilled in the art.

[0055] The present invention has no special limitation on the operation of adding the super absorbent resin, as long as it is ensured to be evenly mixed with the dried product.

[0056] The present invention also provides a nursing pad, comprising a hot air non-woven fabric, an absorbent core and a leak-proof bottom film arranged in sequence from top to bottom;

[0057] The absorbent core includes a first absorbent sanitary paper layer, a fluff pulp layer and a second absorbent sanitary paper layer arranged in sequence from top to bottom; a mixture containing microcapsules is contained between the first absorbent sanitary paper layer and the fluff pulp layer; the mixture containing microcapsules is the mixture containing microcapsules described in the above technical solution or the mixture containing microcapsules prepared by the preparation method described in the above technical solution.

[0058] The nursing pad provided by the present invention comprises hot air non-woven fabric.

[0059] In the present invention, the weight of the hot air nonwoven fabric is preferably 20 to 30 g / m 2 The thickness of the hot air nonwoven fabric is preferably 0.3 to 0.5 mm; the fiber fineness of the hot air nonwoven fabric is preferably 1.5 to 2.5 D. As an embodiment, the gram weight of the hot air nonwoven fabric can be specifically 20 g / m 2 , 21g / m 2 , 22g / m 2 , 23g / m 2 , 24g / m 2 , 25g / m 2 , 26g / m 2 , 27g / m 2 , 28g / m 2 , 29g / m 2 or 30g / m 2The thickness of the air-through nonwoven fabric can be 0.3 mm, 0.4 mm, or 0.5 mm. The fiber fineness of the air-through nonwoven fabric can be 1.5D, 1.8D, 2.0D, 2.2D, or 2.5D. The present invention does not specifically limit the size of the air-through nonwoven fabric and can be selected according to actual needs. In one embodiment, the size of the air-through nonwoven fabric can be 60 cm by 90 cm.

[0060] The air-through nonwoven fabric described herein has high loft, a soft feel, and excellent air and water permeability. Its fiber pores can temporarily store more than 10 times its own weight in liquid. Its numerous through-holes, low density, and loose structure provide excellent air permeability, allowing it to adhere closely to the wearer's body, promoting rapid urine penetration while effectively preventing back-seepage and maintaining a dry surface. The source of the air-through nonwoven fabric is not particularly limited; commercially available products known to those skilled in the art can be used.

[0061] The nursing pad provided by the present invention also includes a leak-proof bottom film.

[0062] In the present invention, the leak-proof bottom film is preferably a PE leak-proof bottom film, more preferably a reinforced wear-resistant PE leak-proof bottom film; the thickness of the leak-proof bottom film is preferably 0.02 to 0.03 mm. In the present invention, the dimensions of the leak-proof bottom film are preferably the same as those of the air-through nonwoven fabric. In one embodiment, the reinforced wear-resistant PE leak-proof bottom film has an abrasion loss of 8 mg / 1000 r (Taber abrasion test).

[0063] The PE leak-proof bottom film of the present invention uses a reinforced wear-resistant PE leak-proof bottom film, which is both breathable and waterproof, and can effectively prevent urine leakage. The present invention does not specifically limit the source of the leak-proof bottom film, and commercially available products known to those skilled in the art can be used.

[0064] The nursing pad provided by the present invention further comprises an absorbent core. In the present invention, the size of the absorbent core is preferably the same as that of the hot air nonwoven fabric.

[0065] In the present invention, the absorbent core comprises a first absorbent sanitary paper layer, a fluff pulp layer and a second absorbent sanitary paper layer arranged in sequence from top to bottom; a mixture containing microcapsules is contained between the first absorbent sanitary paper layer and the fluff pulp layer.

[0066] The absorbent core provided by the present invention comprises a first absorbent sanitary paper layer.

[0067] In the present invention, the gram weight of the first absorbent toilet paper is preferably 18 to 22 g / m 2 The pH value of the first absorbent sanitary paper is preferably 6.0 to 6.5; the longitudinal tensile strength of the first absorbent sanitary paper is preferably ≥ 1.2 kN / m. As an embodiment, the gram weight of the first absorbent sanitary paper can be specifically 18 g / m2 , 19g / m 2 , 20g / m 2 , 21g / m 2 or 22g / m 2 ; The pH value of the first absorbent toilet paper may specifically be 6.0, 6.1, 6.2, 6.3, 6.4 or 6.5.

[0068] The first absorbent toilet paper of the present invention is primarily composed of fibers with numerous interstices. Liquids such as urine can pass through these interstices to create a capillary effect, thereby significantly retaining the liquid. The present invention does not specifically limit the source of the first absorbent toilet paper; commercially available products familiar to those skilled in the art can be used.

[0069] The absorbent core provided by the present invention further comprises a fluff pulp layer.

[0070] In the present invention, the fiber length of the fluff pulp is preferably 1.5 to 2.0 mm; the fluffiness of the fluff pulp is preferably ≥ 8 cm 3 / g; the water absorption rate of the fluff pulp is preferably ≥8 times.

[0071] The fluff pulp of the present invention has excellent water absorption, hygroscopicity and air permeability. The present invention has no particular limitation on the source of the fluff pulp, and commercially available products known to those skilled in the art can be used.

[0072] The absorbent core provided by the present invention further comprises a second absorbent toilet paper layer.

[0073] In the present invention, the second absorbent toilet paper is preferably the same as the first absorbent toilet paper, and will not be described in detail here.

[0074] In the present invention, a mixture containing microcapsules is contained between the first absorbent sanitary paper layer and the fluff pulp layer.

[0075] In the present invention, the ratio of the mass of the mixture containing microcapsules to the area of the fluff pulp layer in the absorbent core is preferably 0.0018 to 0.0022 g / cm 2 As an embodiment, in the absorbent core, the mass ratio of the mixture containing microcapsules to the area of the fluff pulp layer can be specifically 0.0018 g / cm 2 , 0.0019g / cm 2 , 0.0020g / cm 2 , 0.0021g / cm 2 or 0.0022g / cm 2 The present invention controls the mass ratio of the mixture containing microcapsules in the absorbent core to the area ratio of the fluff pulp layer within the above range, which can further improve the antibacterial and deodorizing properties of the nursing pad.

[0076] The nursing pad provided by the present invention is convenient, timely and economical. Users do not need to perform additional urine collection and testing operations, and health index monitoring can be completed during daily use of the nursing pad. It is particularly suitable for people with limited mobility or who need long-term monitoring. It can monitor relevant indicators in urine in real time. Once an abnormality is found, it can be discovered in time, providing a basis for early diagnosis and treatment. Compared with frequent visits to the hospital for urine testing, the overall cost is lower, and long-term use can save costs.

[0077] In the present invention, the preparation method of the nursing pad preferably includes the following steps:

[0078] 1) Laying the fluff pulp on a mesh to obtain a fluff pulp layer;

[0079] 2) evenly spreading the mixture containing microcapsules on the surface of the fluff pulp layer obtained in step 1) to obtain a fluff pulp layer loaded with the mixture containing microcapsules;

[0080] 3) laminating the first absorbent sanitary paper layer, the fluff pulp layer loaded with the mixture containing microcapsules obtained in step 2), and the second absorbent sanitary paper layer to obtain an absorbent core;

[0081] 4) The hot air nonwoven fabric, the absorbent core obtained in step 3) and the leak-proof bottom film are laminated, and hot pressed and embossed in sequence to obtain a nursing pad.

[0082] In the present invention, the fluff pulp is preferably laid on a mesh to obtain a fluff pulp layer.

[0083] In the present invention, the thickness of the fluff pulp layer is preferably 3 to 5 mm; the weight of the fluff pulp layer is preferably 200 to 300 g / m 2 .

[0084] The present invention has no special limitation on the operation of laying the web. It is sufficient to adopt a laying technical solution well known to those skilled in the art to ensure that the thickness of the fluff pulp layer is within the above range.

[0085] As an embodiment, the present invention uses an air-laid machine to lay the fluff pulp at a laying speed of 10 to 15 m / min. The present invention has no particular limitation on the model of the air-laid machine, and commercially available equipment familiar to those skilled in the art can be used.

[0086] After obtaining the fluff pulp layer, the present invention preferably spreads the mixture containing microcapsules evenly on the surface of the fluff pulp layer to obtain the fluff pulp layer loaded with the mixture containing microcapsules.

[0087] In the present invention, the mass ratio of the mixture containing microcapsules to the area of the villus pulp layer is preferably 0.0018 to 0.0022 g / cm 2 .

[0088] The present invention has no special limitation on the spreading operation. A spreading technical solution well known to those skilled in the art can be used to ensure that the mixture containing the microcapsules can be evenly spread on the surface of the fluff pulp layer.

[0089] After obtaining the fluff pulp layer loaded with the mixture containing microcapsules, the present invention preferably stacks the first absorbent sanitary paper layer, the fluff pulp layer loaded with the mixture containing microcapsules, and the second absorbent sanitary paper layer to obtain an absorbent core.

[0090] In the present invention, the first absorbent toilet paper and the second absorbent toilet paper are preferably cut.

[0091] As an embodiment, the present invention adopts a circular knife slitting machine for cutting; the circular knife slitting machine has a circular knife slitting accuracy of ±0.5mm and a slitting speed of 80 to 100m / min.

[0092] The present invention has no special limitation on the sizes of the first water-absorbing toilet paper and the second water-absorbing toilet paper after cutting, and they can be selected according to actual needs.

[0093] The present invention has no special limitation on the superposition operation, and the three can be superimposed in sequence.

[0094] After obtaining the absorbent core, the present invention preferably laminates the hot air nonwoven fabric, the absorbent core and the leak-proof bottom film, and sequentially performs heat pressing and embossing to obtain a nursing pad.

[0095] In the present invention, the leak-proof bottom film is preferably subjected to surface embossing and anti-slip treatment before use.

[0096] The present invention has no special limitation on the operation of the surface embossing anti-slip treatment, and the technical solution of the surface embossing anti-slip treatment well known to those skilled in the art can be adopted.

[0097] In the present invention, the hot air nonwoven fabric and the leak-proof bottom film are preferably cut.

[0098] As an embodiment, the present invention adopts a circular knife slitting machine for cutting; the circular knife slitting machine has a circular knife cutting accuracy of ±0.5mm and a cutting speed of 80 to 100m / min.

[0099] The present invention has no special limitation on the sizes of the cut hot air non-woven fabric and the leak-proof bottom film, which can be selected according to actual needs.

[0100] The present invention has no special limitation on the superposition operation, and the three can be superimposed in sequence.

[0101] In the present invention, the hot pressing temperature is preferably 98 to 102° C., more preferably 100° C.; the hot pressing pressure is preferably 0.3 to 0.6 MPa; and the hot pressing time is preferably 8 to 10 seconds.

[0102] After the hot pressing is completed, the present invention preferably cools the hot pressed product before embossing.

[0103] The present invention has no special limitation on the cooling operation, and cooling to room temperature can be performed using cooling technical solutions well known to those skilled in the art.

[0104] In the present invention, the shape of the embossing is preferably a rhombus; the acute angle of the rhombus is preferably 40 to 50°, more preferably 45°; and the side length of the rhombus is preferably 1 to 3 mm.

[0105] In the present invention, the embossing depth is preferably 0.3 to 0.5 mm; the embossing pressure is preferably 5 to 8 MPa; and the embossing holding time is preferably 0.3 to 0.8 s.

[0106] As an embodiment, the present invention performs embossing by an embossing roller; the temperature of the embossing roller is 100-120°C.

[0107] After the embossing is completed, the present invention preferably sequentially cools, seals the edges, and trims the edges to obtain a nursing pad.

[0108] The present invention has no special limitation on the cooling operation, and cooling to room temperature can be performed using cooling technical solutions well known to those skilled in the art.

[0109] The present invention preferably uses ultrasound for edge sealing; the frequency of the ultrasound is preferably 15 to 25 kHz, more preferably 20 kHz; the edge sealing width is preferably 9 to 11 mm, more preferably 10 mm.

[0110] The present invention has no special limitation on the edge trimming operation. The redundant edges can be cut off and the edges can be trimmed neatly using edge trimming technical solutions well known to those skilled in the art.

[0111] The present invention performs embossing and controls various embossing parameters to form 3D micro-diamond embossing, which has fast diversion, can accelerate diversion and absorption, reduce the contact of urine and the like with the skin, and at the same time ensure that the mixture containing the microcapsules is evenly distributed and positioned in the nursing pad, making the visual indication of the urine pH value more obvious and more uniform.

[0112] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions of the present invention. Obviously, the embodiments described are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0113] Example 1

[0114] A mixture containing microcapsules is prepared from the following raw materials, calculated by mass percentage:

[0115] Methyl red (≥500 mesh) 0.1%, bromothymol blue (≥500 mesh) 0.5%, persimmon extract 5%, polyhexamethyleneguanidine aqueous solution (the mass content of polyhexamethyleneguanidine in the polyhexamethyleneguanidine aqueous solution is 20%) 3%, PEG-4000 1.5%, cyclodextrin 36.9%, sodium polyacrylate (≥100 mesh) 28% and deionized water (pH 6.0) 25%;

[0116] The preparation method of the mixture containing microcapsules is as follows: (1) mixing persimmon extract, polyhexamethyleneguanidine aqueous solution, PEG-4000 and deionized water to obtain a mixed solution;

[0117] (2) Methyl red, bromothymol blue, cyclodextrin and the mixed solution obtained in step (1) are mixed and ground for 30 minutes, dried, and then sodium polyacrylate is added and mixed uniformly to obtain a mixture containing microcapsules.

[0118] Application Example 1

[0119] A nursing pad is composed of a hot air non-woven fabric, an absorbent core and a PE leak-proof bottom film arranged in sequence from top to bottom;

[0120] The absorbent core is composed of a first absorbent sanitary paper layer, a fluff pulp layer, and a second absorbent sanitary paper layer arranged in sequence from top to bottom; the mixture containing microcapsules in Example 1 is contained between the first absorbent sanitary paper layer and the fluff pulp layer;

[0121] The preparation method of the nursing pad is:

[0122] (1) Hot air nonwoven fabric (weight 20g / m 2 , thickness 0.3mm, fiber fineness 1.5D), absorbent toilet paper (weight 18g / m 2 , pH value 6.25, longitudinal tensile strength 1.2kN / m) and PE leak-proof bottom film (thickness 0.03mm, surface embossed anti-slip treatment) are cut into 60cm*90cm by a circular knife slitting machine, with a circular knife slitting accuracy of ±0.5mm and a slitting speed of 80m / min;

[0123] (2) Use an air-laid machine to lay the fluff pulp into a uniform fluff pulp layer with a gram weight of 200g / m 2 , speed 10m / min, thickness 3mm;

[0124] (3) The mixture containing microcapsules is evenly spread on the surface of the villi pulp layer. The mass ratio of the mixture containing microcapsules to the area of the villi pulp layer is 0.0018 g / cm 2 , and then laying absorbent toilet paper on the bottom of the fluff pulp layer and on the top of the mixture containing the microcapsules to obtain an absorbent core;

[0125] (4) Cover the upper part of the absorbent core with hot air non-woven fabric and the lower part of the absorbent core with PE leakproof bottom film, perform hot pressing at 100±2℃ and 0.3MPa for 8s, cool, and use an embossing roller for embossing. The temperature of the embossing roller is 105℃, the mold is a 45° diamond, the embossing depth is 0.3mm, the diamond side length is 1.5mm, the pressure is 5MPa, and the holding time is 0.3s. After cooling, use ultrasonic wave to seal the edge at a frequency of 20kHz and an edge sealing width of 10mm, and then perform edge trimming to obtain a nursing pad.

[0126] Example 2

[0127] A mixture containing microcapsules is prepared from the following raw materials, calculated by mass percentage:

[0128] Methyl red (≥500 mesh) 0.05%, bromothymol blue (≥500 mesh) 0.25%, persimmon extract 1%, polyhexamethyleneguanidine aqueous solution (the mass content of polyhexamethyleneguanidine in the polyhexamethyleneguanidine aqueous solution is 20%) 1%, PEG-40000 0.5%, cyclodextrin 52.2%, sodium polyacrylate (≥100 mesh) 25% and deionized water (pH 6.0) 20%;

[0129] The preparation method of the mixture containing microcapsules is the same as that of Example 1.

[0130] Application Example 2

[0131] A nursing pad is composed of a hot air non-woven fabric, an absorbent core and a PE leak-proof bottom film arranged in sequence from top to bottom;

[0132] The absorbent core is composed of a first absorbent sanitary paper layer, a fluff pulp layer, and a second absorbent sanitary paper layer arranged in sequence from top to bottom; the mixture containing microcapsules in Example 2 is contained between the first absorbent sanitary paper layer and the fluff pulp layer;

[0133] The preparation method of the nursing pad is:

[0134] (1) Hot air nonwoven fabric (weight 25g / m 2, thickness 0.4mm, fiber fineness 1.8D), absorbent toilet paper (weight 20g / m 2 , pH value 6.36, longitudinal tensile strength 1.5kN / m) and PE leak-proof bottom film (thickness 0.03mm, surface embossed anti-slip treatment) are cut into 60cm*90cm by a circular knife slitting machine, with a circular knife slitting accuracy of ±0.5mm and a slitting speed of 90m / min;

[0135] (2) Use an air-laid machine to lay the fluff pulp into a uniform fluff pulp layer with a gram weight of 266g / m 2 , speed 10m / min, thickness 4mm;

[0136] (3) The mixture containing microcapsules was evenly spread on the surface of the villi pulp layer. The mass ratio of the mixture containing microcapsules to the area of the villi pulp layer was 0.0022 g / cm 2 , and then laying absorbent toilet paper on the bottom of the fluff pulp layer and on the top of the mixture containing the microcapsules to obtain an absorbent core;

[0137] (4) Cover the upper part of the absorbent core with hot air non-woven fabric and the lower part of the absorbent core with PE leakproof bottom film, perform hot pressing at 100±2℃ and 0.4MPa for 10s, cool, and use an embossing roller for embossing. The temperature of the embossing roller is 110℃, the mold is a 45° diamond, the embossing depth is 0.4mm, the diamond side length is 1.8mm, the pressure is 6MPa, and the holding time is 0.5s. After cooling, use ultrasonic wave to seal the edge at a frequency of 20kHz and an edge sealing width of 10mm, and then perform edge trimming to obtain a nursing pad.

[0138] Example 3

[0139] A mixture containing microcapsules is prepared from the following raw materials, calculated by mass percentage:

[0140] Methyl red (≥500 mesh) 0.06%, bromothymol blue (≥500 mesh) 0.3%, persimmon extract 2%, polyhexamethyleneguanidine aqueous solution (the mass content of polyhexamethyleneguanidine in the polyhexamethyleneguanidine aqueous solution is 20%) 1%, PEG-4000 1%, cyclodextrin 46.64%, sodium polyacrylate (≥100 mesh) 26% and deionized water (pH 6.0) 23%;

[0141] The preparation method of the mixture containing microcapsules is the same as that of Example 1.

[0142] Application Example 3

[0143] A nursing pad is composed of a hot air non-woven fabric, an absorbent core and a PE leak-proof bottom film arranged in sequence from top to bottom;

[0144] The absorbent core is composed of a first absorbent sanitary paper layer, a fluff pulp layer, and a second absorbent sanitary paper layer arranged in sequence from top to bottom; the mixture containing microcapsules in Example 3 is contained between the first absorbent sanitary paper layer and the fluff pulp layer;

[0145] The preparation method of the nursing pad is:

[0146] (1) Hot air nonwoven fabric (weight 25g / m 2 , thickness 0.4mm, fiber fineness 1.8D), absorbent toilet paper (weight 20g / m 2 , pH value 6.36, longitudinal tensile strength 1.5kN / m) and PE leak-proof bottom film (thickness 0.02mm, surface embossed anti-slip treatment) are cut into 60cm*90cm by a circular knife slitting machine, with a circular knife slitting accuracy of ±0.5mm and a slitting speed of 90m / min;

[0147] (2) Use an air-laid machine to lay the fluff pulp into a uniform fluff pulp layer with a gram weight of 266g / m 2 , speed 10m / min, thickness 4mm;

[0148] (3) The mixture containing microcapsules is evenly spread on the surface of the villi pulp layer. The mass ratio of the mixture containing microcapsules to the area of the villi pulp layer is 0.0020 g / cm 2 , and then laying absorbent toilet paper on the bottom of the fluff pulp layer and on the top of the mixture containing the microcapsules to obtain an absorbent core;

[0149] (4) Cover the upper part of the absorbent core with hot air non-woven fabric and the lower part of the absorbent core with PE leakproof bottom film, perform hot pressing at 100±2℃ and 0.3MPa for 10s, cool, and use an embossing roller for embossing. The temperature of the embossing roller is 105℃, the mold is a 45° diamond, the embossing depth is 0.3mm, the diamond side length is 1.5mm, the pressure is 5MPa, and the holding time is 0.3s. After cooling, use ultrasonic wave to seal the edge at a frequency of 20kHz and an edge sealing width of 10mm, and then perform edge trimming to obtain a nursing pad.

[0150] Example 4

[0151] A mixture containing microcapsules is prepared from the following raw materials, calculated by mass percentage:

[0152] Methyl red (≥500 mesh) 0.08%, bromothymol blue (≥500 mesh) 0.4%, persimmon extract 3%, polyhexamethyleneguanidine aqueous solution (the mass content of polyhexamethyleneguanidine in the polyhexamethyleneguanidine aqueous solution is 20%) 2%, PEG-4000 1%, cyclodextrin 45.52%, sodium polyacrylate (≥100 mesh) 26% and deionized water (pH 6.0) 22%;

[0153] The preparation method of the mixture containing microcapsules is the same as that of Example 1.

[0154] Application Example 4

[0155] A nursing pad is composed of a hot air non-woven fabric, an absorbent core and a PE leak-proof bottom film arranged in sequence from top to bottom;

[0156] The absorbent core is composed of a first absorbent sanitary paper layer, a fluff pulp layer, and a second absorbent sanitary paper layer arranged in sequence from top to bottom; the mixture containing microcapsules in Example 4 is contained between the first absorbent sanitary paper layer and the fluff pulp layer;

[0157] The preparation method of the nursing pad is:

[0158] (1) Hot air nonwoven fabric (weight 20g / m 2 , thickness 0.3mm, fiber fineness 1.5D), absorbent toilet paper (weight 18g / m 2 , pH value 6.25, longitudinal tensile strength 1.2kN / m) and PE leak-proof bottom film (thickness 0.03mm, surface embossed anti-slip treatment) are cut into 60cm*90cm by a circular knife slitting machine, with a circular knife slitting accuracy of ±0.5mm and a slitting speed of 80m / min;

[0159] (2) Use an air-laid machine to lay the fluff pulp into a uniform fluff pulp layer with a gram weight of 200g / m 2 , speed 10m / min, thickness 3mm;

[0160] (3) The mixture containing microcapsules is evenly spread on the surface of the villi pulp layer. The mass ratio of the mixture containing microcapsules to the area of the villi pulp layer is 0.0020 g / cm 2 , and then laying absorbent toilet paper on the bottom of the fluff pulp layer and on the top of the mixture containing the microcapsules to obtain an absorbent core;

[0161] (4) Cover the upper part of the absorbent core with hot air non-woven fabric and the lower part of the absorbent core with PE leakproof bottom film, perform hot pressing at 100±2℃ and 0.3MPa for 8s, cool, and use an embossing roller for embossing. The temperature of the embossing roller is 105℃, the mold is a 45° diamond, the embossing depth is 0.3mm, the diamond side length is 1.5mm, the pressure is 5MPa, and the holding time is 0.3s. After cooling, use ultrasonic wave to seal the edge at a frequency of 20kHz and an edge sealing width of 10mm, and then perform edge trimming to obtain a nursing pad.

[0162] Example 5

[0163] A mixture containing microcapsules is prepared from the following raw materials, calculated by mass percentage:

[0164] Methyl red (≥500 mesh) 0.06%, bromothymol blue (≥500 mesh) 0.3%, persimmon extract 3%, polyhexamethyleneguanidine aqueous solution (the mass content of polyhexamethyleneguanidine in the polyhexamethyleneguanidine aqueous solution is 20%) 2%, PEG-4000 1%, cyclodextrin 45.64%, sodium polyacrylate (≥100 mesh) 27% and deionized water (pH 6.0) 21%;

[0165] The preparation method of the mixture containing microcapsules is the same as that of Example 1.

[0166] Application Example 5

[0167] A nursing pad is composed of a hot air non-woven fabric, an absorbent core and a PE leak-proof bottom film arranged in sequence from top to bottom;

[0168] The absorbent core is composed of a first absorbent sanitary paper layer, a fluff pulp layer, and a second absorbent sanitary paper layer arranged in sequence from top to bottom; the mixture containing microcapsules in Example 5 is contained between the first absorbent sanitary paper layer and the fluff pulp layer;

[0169] The preparation method of the nursing pad is:

[0170] (1) Hot air nonwoven fabric (weight 20g / m 2 , thickness 0.3mm, fiber fineness 1.5D), absorbent toilet paper (weight 18g / m 2 , pH value 6.25, longitudinal tensile strength 1.2kN / m) and PE leak-proof bottom film (thickness 0.02mm, surface embossed anti-slip treatment) are cut into 60cm*90cm by a circular knife slitting machine, with a circular knife slitting accuracy of ±0.5mm and a slitting speed of 80m / min;

[0171] (2) Use an air-laid machine to lay the fluff pulp into a uniform fluff pulp layer with a gram weight of 200g / m 2 , speed 10m / min, thickness 3mm;

[0172] (3) The mixture containing microcapsules is evenly spread on the surface of the villi pulp layer. The mass ratio of the mixture containing microcapsules to the area of the villi pulp layer is 0.0020 g / cm 2 , and then laying absorbent toilet paper on the bottom of the fluff pulp layer and on the top of the mixture containing the microcapsules to obtain an absorbent core;

[0173] (4) Cover the upper part of the absorbent core with hot air non-woven fabric and the lower part of the absorbent core with PE leakproof bottom film, perform hot pressing at 100±2℃ and 0.3MPa for 8s, cool, and use an embossing roller for embossing. The temperature of the embossing roller is 105℃, the mold is a 45° diamond, the embossing depth is 0.3mm, the diamond side length is 1.5mm, the pressure is 5MPa, and the holding time is 0.3s. After cooling, use ultrasonic wave to seal the edge at a frequency of 20kHz and an edge sealing width of 10mm, and then perform edge trimming to obtain a nursing pad.

[0174] Comparative Example 1

[0175] The methyl red and bromothymol blue in Example 3 were omitted, and the amount of cyclodextrin was modified to 47%. Other parameters were the same as in Example 3 to obtain a mixture.

[0176] Comparative Application Example 1

[0177] The difference from Application Example 3 is that the mixture in Comparative Example 1 is used, and the other parameters are the same as those in Application Example 3.

[0178] Comparative Example 2

[0179] The persimmon extract and the polyhexamethyleneguanidine aqueous solution in Example 3 were omitted, and the amount of cyclodextrin was modified to 49.64%. Other parameters were the same as in Example 3 to obtain a mixture.

[0180] Comparative Application Example 2

[0181] The difference from Application Example 3 is that the mixture in Comparative Example 2 is used, and the other parameters are the same as those in Application Example 3.

[0182] Comparative Example 3

[0183] The cyclodextrin in Example 3 was omitted, and the amount of PEG-4000 was modified to 47.64%. Other parameters were the same as those in Example 3 to obtain a mixture.

[0184] Comparative Application Example 3

[0185] The difference from Application Example 3 is that the mixture in Comparative Example 3 is used, and the other parameters are the same as those in Application Example 3.

[0186] The deodorization rate, antibacterial rate, antibacterial rate after stability test and color development effect at different pH values of the nursing pads in application examples 1 to 5 and comparative application examples 1 to 3 were tested. The results are shown in Table 1.

[0187] Deodorization rate: The test method is carried out in accordance with QB / T 2761-2006 "Determination of purification effect of indoor air purification products", and the odor sources are ammonia water (1wt%) and hydrogen sulfide solution (0.1wt%).

[0188] Bacterial inhibition rate: The test method refers to Appendix C of GB 15979-2002 "Hygienic Standard for Disposable Sanitary Products". The test strains are Staphylococcus aureus (ATCC 6538), Escherichia coli (ATCC 25922) and Candida albicans (ATCC10231).

[0189] Stability test: Place the nursing pad in a constant temperature box at 37-40℃ for 3 months, maintain relative humidity >75%, and conduct antibacterial rate test.

[0190] Color indication performance: Prepare 250 mL of buffer solutions with pH values of 2.0, 4.0, 5.0, 6.0, 7.0, 8.0, 9.18, and 11.0 respectively, and transfer 20 mL into a burette. The water outlet of the burette should be 10 cm away from the nursing pad. Open the burette and let the liquid flow naturally. After 1 minute, observe the color of the nursing pad.

[0191] Table 1 Deodorization rate, antibacterial rate, antibacterial rate after stability test and color development effect at different pH values of the nursing pads in Application Examples 1 to 5 and Comparative Application Examples 1 to 3

[0192]

[0193]

[0194]

[0195] Combined with the data in Application Examples 1 to 5, Comparative Application Example 1, and Table 1, the nursing pad provided by the present invention has a pH health indicator color display function, which will display different colors according to the different pH values of urine. When the pH value is ≤ 4.0, it displays red, and the stronger the acidity, the darker the color; when the pH value is 5.0, it displays orange; when the pH value is 6.0, it displays yellow; when the pH value is 7.0, it displays light green; when the pH value is 8.0, it displays blue-green; when the pH value is greater than 8.0, it displays blue, and the stronger the alkalinity, the darker the color.

[0196] Combined with the data in Application Examples 1-5, Comparative Application Example 2, and Table 1, the nursing pad provided by the present invention exhibits excellent antibacterial properties, with inhibition rates exceeding 96% against Staphylococcus aureus, Escherichia coli, and Candida albicans, demonstrating a strong antibacterial effect. Accelerated testing at 37°C maintained an inhibition rate of over 96%, consistent with pre-test results. This demonstrates that the antibacterial effect of the nursing pad provided by the present invention is maintained for at least two years at room temperature. It also effectively removes major odor components in urine, such as ammonia and hydrogen sulfide, effectively eliminating all urine odors. Urine is rapidly absorbed and decomposed by the microcapsules in the pad, resulting in a highly efficient deodorization process.

[0197] Combining the data in Application Examples 1 to 5, Comparative Application Example 3, and Table 1, the deodorization rate and antibacterial rate were reduced in Comparative Application Example 3, which did not add the coating wall material cyclodextrin. After the stability test, the antibacterial rate was significantly attenuated, and the antibacterial rate was less than 90%. Although the nursing pad has a color development function, the color distribution is uneven, making it difficult to identify. This shows that by adding cyclodextrin as a microcapsule wall material and using microcapsule coating technology to protect the indicator (methyl red, bromothymol blue), persimmon extract, polyhexamethylene guanidine and other ingredients, it is possible to improve stability, improve dispersibility, control release, and achieve slow and sustained release. When the nursing pad is used, it can effectively release the antibacterial and deodorizing effects, making the visual indication of urine pH value more obvious and more uniform.

[0198] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as within the scope of protection of the present invention.

Claims

1. A mixture containing microcapsules, comprising the following raw materials, calculated by mass percentage: Methyl red 0.05%-0.1%, bromothymol blue 0.25%-0.5%, persimmon extract 1%-5%, polyhexamethyleneguanidine aqueous solution 1%-3%, polyethylene glycol 0.5%-1.5%, cyclodextrin 36.9%-52.2%, super absorbent resin 25%-28% and water 20%-25%.

2. The microcapsule-containing mixture according to claim 1, characterized in that The highly water-absorbent resin is sodium polyacrylate; the mesh number of the sodium polyacrylate is ≥100 meshes.

3. The microcapsule-containing mixture according to claim 1, characterized in that The polyethylene glycol is polyethylene glycol 4000.

4. The microcapsule-containing mixture according to claim 1, characterized in that The mesh number of the methyl red is ≥500 meshes.

5. The microcapsule-containing mixture according to claim 1, characterized in that The mesh number of the bromothymol blue is ≥500 meshes.

6. The method for preparing the mixture containing microcapsules according to any one of claims 1 to 5, comprising the following steps: (1) mixing a persimmon extract, a polyhexamethyleneguanidine aqueous solution, polyethylene glycol, and water to obtain a mixed solution; (2) Methyl red, bromothymol blue, cyclodextrin and the mixed solution obtained in step (1) are mixed and dried, and then a super absorbent resin is added to obtain a mixture containing microcapsules.

7. A nursing pad comprising, arranged from top to bottom, a hot air non-woven fabric, an absorbent core, and a leak-proof bottom film; The absorbent core includes a first absorbent sanitary paper layer, a fluff pulp layer and a second absorbent sanitary paper layer arranged in sequence from top to bottom; a mixture containing microcapsules is contained between the first absorbent sanitary paper layer and the fluff pulp layer; the mixture containing microcapsules is the mixture containing microcapsules described in any one of claims 1 to 5 or the mixture containing microcapsules prepared by the preparation method described in claim 6.

8. The nursing pad according to claim 7, characterized in that In the absorbent core, the mass ratio of the mixture containing microcapsules to the area of the fluff pulp layer is 0.0018 to 0.0022 g / cm 2 .

9. The nursing pad according to claim 7, characterized in that The thickness of the hot air nonwoven fabric is 0.3-0.5 mm.

10. The nursing pad according to claim 7, characterized in that The thickness of the leak-proof bottom film is 0.02-0.03 mm.

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