Preparation of nifuratel and nysfungin vaginal soft capsules

A technology of nifuratel nystatin and nifuratel, which is applied in the direction of medical preparations containing active ingredients, pill delivery, organic active ingredients, etc., and can solve problems such as increased glycogen content, bacterial mutation, and human hazards , to achieve the effect of high effective drug concentration, promoting disease recovery, and convenient use
CN101332192AInactive Publication Date: 2008-12-31李国栋

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
李国栋
Publication Date
2008-12-31
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to preparation of a new medicine Nifuratel nysfungin vagina tablet for gynecologic antisepsis and anti-inflammation. Nifuratel nysfungin can play a more complete role in curing mixed vagina infection (candida, trichomonas and bacteria) and pathogen which can not be or can not be timely and clearly diagnosed and preventing mildew secondary infection and recurrence after the treatment of other medicines. The present invention can be used for curing bacterial vaginopathy, trichomonas vaginitis, monilial vulvovaginitis, and vagina mixed infection. The advantage of the present invention lies in that the added pH buffer system ensures pH of the medicine is within 3.5 to 4.0 close to the physiological pH of vagina, thus effectively protecting the physiological environment of vagina, providing the appropriate living conditions beneficial to flora in vagina and promoting the recovery of diseases.
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Description

technical field

[0001] The invention relates to the preparation of a new antibacterial and anti-inflammatory drug nifuratel nystatin vaginal tablet for gynecology. Background technique

[0002] Bacterial vaginosis (BV) and vaginal trichomoniasis are common multiple-occurring diseases in obstetrics and gynecology. Hurley et al. reported that about 75% of women of childbearing age had one episode of BV, and about 5% had recurrent episodes. Worldwide There are more than 200 million people infected with Trichomonas vaginalis. BV often coexists with Trichomonas vaginitis. It has been reported that 86% of women with positive trichomonas culture have BV. There are also domestic surveys showing that among 227 gynecological outpatients with increased vaginal discharge or peculiar smell, 120 cases were BV patients, accounting for 43.33%, and 19.17% of them were combined with trichomonas infection (23 / 120); 36 cases of trichomonas vaginitis ( 13%), 31 cases (11.1%) of candidal vaginit...

Claims

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