Preparation of nifuratel and nysfungin vaginal soft capsules
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 李国栋
- Publication Date
- 2008-12-31
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention relates to the preparation of a new antibacterial and anti-inflammatory drug nifuratel nystatin vaginal tablet for gynecology. Background technique
[0002] Bacterial vaginosis (BV) and vaginal trichomoniasis are common multiple-occurring diseases in obstetrics and gynecology. Hurley et al. reported that about 75% of women of childbearing age had one episode of BV, and about 5% had recurrent episodes. Worldwide There are more than 200 million people infected with Trichomonas vaginalis. BV often coexists with Trichomonas vaginitis. It has been reported that 86% of women with positive trichomonas culture have BV. There are also domestic surveys showing that among 227 gynecological outpatients with increased vaginal discharge or peculiar smell, 120 cases were BV patients, accounting for 43.33%, and 19.17% of them were combined with trichomonas infection (23 / 120); 36 cases of trichomonas vaginitis ( 13%), 31 cases (11.1%) of candidal vaginit...