The invention discloses a traditional Chinese medicine lotion for treating gynecological vaginitis and a preparation method thereof. The traditional Chinese medicine lotion is prepared from saffron crocus, honeysuckle, aloe, folium artemisiae argyi, the tuber of stemona, japanese conehead herb, herba eupatorii lindleyani, radix sophorae flavescentis, felwort, panax notoginseng, fiveleaf akebia fruit, corydalis tuber, lotus plumule, cape jasmine, rhizoma alismatis, corn stigma and folium ginkgo. The preparation method comprises the following steps: weighing the various traditional Chinese medicine raw materials according to a ratio, cleaning and airing; adding water, decocting twice, merging the decoction twice, filtering, concentrating the filtrate into clear paste, adding ethanol for extracting, standing and filtering, concentrating and evaporating to recover the ethanol, thereby obtaining the product. The compatibility of the medicines is reasonable, and the prepared traditional Chinese medicine lotion disclosed by the invention has the pharmacological actions of broad spectrum, high efficiency, inflammation diminishment and pain relief, itching relief and anti-trichomonad effect, can achieve the effects of promoting vaginal epithelium synthesis and secretion of glycogens, promoting production of vaginal lactobacillus and restoring a normal vaginal ecological system, can be used for treating colpitis mycotica and general vaginitis, and has the advantages of obvious curative effect, zero side effect and low reoccurrence rate.