97 results about "Burned skin" patented technology

The invention provides a near-infrared spectrum imaging system for diagnosis of depth and area of burn skin necrosis. The near-infrared spectrum imaging system comprises a spectrum imager and a computer-control system. The spectrum imager acquires 1100-2500nm waveband spectral signals of burn skin necrosis tissue of a target area, the spectral signals are subjected to image analyzing and processing through the computer-control system, the depth and area of burn of the target area can be acquired through spectral matching recognition upon a spectral reflectance curve corresponding to each image element in spectral images and a standard spectral reflectance curve in a burn skin necrosis spectral database in a data module and are synthesized into three-dimensional image display of the target area. By the near-infrared spectrum imaging system, the spatial structure of skin changed due to tissue protein denaturation before and after the skin burn can be specified, so that micron-level information about boundaries of normal skin tissue and necrotic tissue and the depth of burn skin necrosis can be provided visually, and clinical diagnosis, treatment and prognosis judgment can be supportively facilitated.

The invention described herein relates to methods for reducing and / or stopping bleeding or fluid loss from open wound, denuded tissue, or burned skin, comprising the step of applying to the open wound, denuded tissue or burned skin a gel-forming composition comprising at least one of the following compositions: a polyacrylic acid having the structural formula [CH2═CHCO2H]n, where n is between 10,000 and 70,000; a polyacrylic acid and a desiccated water soluble organic or inorganic base; polyacrylic acid and a desiccated poorly soluble basic salt, and a polyvinyl alcohol having the structural formula of [CH2═CHOH]n, where n is between 15,000 and 150,000. When the gel-forming composition is applied to the open wound, denuded tissue, or burned skin, its ions react therein in the presence of water from blood or body fluid therein to form an aqueous gel or mucilage having sufficient viscosity and adhesiveness to cover and adhere to the open wound, denuded tissue, or burned skin so that bleeding or fluid loss is thereby reduced and / or stopped.

The invention discloses a skin burn repair material and a preparing method thereof, and belongs to the field of biomedicine. A functional loading substance is added into a polymer to prepare the repair material through the coaxial electrostatic spinning process, and the upper surface layer micro-nano structure is adjusted so that the repair material can resist adhesion of outside microorganisms and bacteria. The prepared repair material containing the functional loading substance with antibacterial, antiphlogistic and repair promoting functions repairs the skin burn area in a targeted mode based on the characteristics of different stages of the burnt skin repair process. The adopted base material has high biocompatibility, secondary damage to the wound region of traditional medical gauze when fresh dressing is changed for a wound is avoided, and secondary infection caused by external factors can be effectively resisted. The skin burn repair material and the preparing method thereof can be effectively applied to biomedicine related fields and have the possibility of extensive clinic application.

The invention relates to hydrogel wound dressing for treating laser cauma and burns and scalds. The active components of the hydrogel wound dressing include an antibacterial agent, a humectant and a stabilizer, wherein the antibacterial agent inhibits adhesion and growth of the wound of laser cauma and surrounding bacteria and can kill various pathogenic bacteria at the cauma part, so as to effectively promote union of the laser cauma. The antibacterial agent adopted by the invention does not generate drug resistance, the humectant can maintain moisture of the wound, promote union of the wound surface, prevent formation of scars and alleviate wound pain. With the adoption of the stabilizer, the hydrogel maintains long-time antibacterial effectiveness. Experiments verify that the hydrogel dressing provided by the invention has the effects of effectively relieving wound pain, controlling local infection, maintaining moisture of wound skins, protecting skins, accelerating and promoting union of wound surface and wound and preventing formation of scars, and can be used for healing laser-burned skin wound surfaces (such as laser mole removal and the like) and wound surfaces of burns and scalds.

The invention relates to compositions for debriding damaged skin comprising at least one enzymatic debriding agent and at least one antiseptic compound comprising heavy metal ions. The present invention further relates to kit and methods for topical debridement of damaged skin, particularly of burned skin.

The present invention is concerned with novel compositions containing fresh or virgin beeswaxes and oil, with and without water, and the utilization of such compositions for the treatment of skin in animals including man, for treatment for first, second, and third degree (partial and full thickness) burns due to sunburn, windburn, scalds, flash flame, electrical contact, chemical contact, cold, and the like, for use as a preventive aid for sunburn, windburns, skin chapping, chafing and the like, for promoting and accelerating the healing of burns, abrasions, lacerations, cuts, scratches, dry skin, chapped skin, wind burned skin, friction-type burns, chafing and the like, for use as a softening and moisturizing agent, for use in the reduction of wrinkles, for use as a topical application to irritations of the skin, including dry lips, chapped skin, abrasions, and the like, for use as an analgesic to be applied topically for the treatment and alleviation of pain in the skin and underlying tissues, for use as a protective barrier between the skin and other irritants, eg, saliva, urine, fecal material, various chemical irritants and the like, and for use as a base to which may be added other agents also promoting treatment, moisturization, protective or preventive measures for the skin.

The invention discloses a pickling method of preserved meat, which mainly comprises the following steps: cutting into strips-smearing seasonings-pickling-smoking-burning skin-cleaning-baking; the pickling steps of the method can lead a meat product to be tasty fast and have good tasting effect, the meat product is salty moderately and can avoid fat oxidation during the pickling process and preserve the fresh flavor of meat; the smoking temperature and the time are reasonably controlled during the smoking process, thereby leading the aroma of smog to be fully absorbed in the meat product and simultaneously avoiding meat stiffening due to excessive dehydration of cells; a condensing tube is adopted for condensing benzopyrene in the smog, thereby reducing the absorption capacity of the benzopyrene on the surface of the meat product and reducing the residual rate; the skin burning step can not only remove hair roots in the meat skin, but also lead the meat skin to be soft after boiling the preserved meat and facilitate the consumption; the cleaning step can clean dust particles on the surface of the meat product and further reduce the residue of the benzopyrene; and the meat product is dried at the specific temperature till the water content reaches 20%-25%, the meat product has good elasticity and high viscosity during the consumption, a consumer can not feel dry and astringent, and the taste is more comfortable.

The invention provides a compound flame-retardant fabric consisting of a refractory fibre layer 1, a refractory heat insulation layer 2 and a comfort layer 3. The refractory fibre layer 1 contains ceramic fibre materials; the refractory heat insulation layer 2 contains heat resisting glass fibres; and the comfort layer 3 is made of a fabric fibre material. The invention discloses a compound flame-retardant fabric which has reasonable structure and simple preparation process. The refractory fibre layer can effectively prevent the fabric from burning in open fire; the heat resisting temperature is as high as 1300 DEG C; the refractory heat insulation layer can effectively prevent high-temperature heat conduction and prevent high temperature from burning skin; the fabric is suitable for producing high-temperature resistant articles such as clothes for fire control, high-temperature glove and the like; and the comfort layer inside the fabric ensures that the fabric has good air permeability and perspiration absorbing performance. The compound flame-retardant fabric is suitable for people to wear and use under high-temperature environment for a long time.

The invention provides a stem cell exosome capable of repairing skin as well as a preparation method and application thereof. The preparation method comprises the following step: transducing decapeptide-12 into mesenchymal stem cell exosome, thereby obtaining the stem cell exosome capable of repairing skin. According to the stem cell exosome capable of repairing skin prepared by the method disclosed by the invention, the invention first discovers that, by binding the mesenchymal stem cell exosome and decapeptide-12 and by utilizing loading capacity and low immunogenicity of exosome cells, thedecapeptide-12 can reach melanocyte so as to further inhibit tyrosinase activity, the inflammatory response can be regulated, and skin related cell regeneration is promoted. The stem cell exosome capable of repairing skin prepared by the invention can achieve effects of eliminating erythema and edema when applied to sun-burned skin, can reduce melanogenesis and further reduce pigmentation and formation of black spots after sunburn, can be applied to the fields of cosmetics, medicines for treating skin diseases and the like, and has obvious effects and important application value.

The invention discloses an application of a self-assembled short-peptide RADA16-1 for preparation of medicine for curing burn wound. Model of rat burned skin is established by using temperature adjusting mode electrical scald instrument and flame. Hydrogel formed by self-assembled short-peptide RADA16-1 and typic medicines for curing burn wound as dressing such as chitosan, collagen, polylactic acid perform therapeutic experiment. The results show that the self-assembled short-peptide RADA16-1 can control the extension of burn wound and edema, promote the ordered rearrangement of collagen of burn wound, burn wound healing, regenerating and repairing the skin and the appendage of skin tissue. Compared with the chitosan, collagen, polylactic acid, the said medicine has better curative effect.

The invention discloses a burn nursing and medicine applying all-in-one machine which comprises a nursing mechanism and a medicine applying mechanism. People can use a driving part to quickly spray liquid medicine to the human body to conduct disinfection when disinfecting burnt skin, the operation of a user is convenient, and the time of nursing staff can be effectively saved in busy places such as a hospital; specifically, a medicine applying piston conducts piston movement in a medicine applying casing, so that medicament is extruded out from small medicine applying holes, and conveniently applied to the burnt skin of a patient; a nursing piston conducts piston movement in a nursing casing, so that liquid medicine is ejected out from small nursing holes to conduct disinfection treatment on the burnt skin; the manual medicine applying and nursing by the nursing staff can be avoided, the manpower is saved, the labor is better saved, nursing and medicine applying can be conducted relatively quickly, and the work efficiency of the nursing staff can be improved.

The invention relates to a moxibustion health care and treatment device. The moxibustion health care and treatment device comprises an outer cup which comprises an outer cup upper portion and an outer cup lower portion which can be separated and connected with each other; a top cover of the outer cup is provided with a smoke discharging hole and a fixing hole, the inner wall of the fixing hole is provided with internal threads, a cylindrical hollow top tube penetrates through the top cover of the outer cup, the outer wall of the top tube is provided with external threads, and the inner wall of the top tube is provided with fixing pieces; and the bottom cover of the outer cup is provided with heat radiation bottom holes, a protective net is arranged inside the outer cup lower portion, and the outer wall of the outer cup lower portion is provided with air inlet holes, a bottom strip and a fixing strap. The moxibustion health care and treatment device further comprises an inner cup, the top of the inner cup is provided with an opening, the inner wall of the inner cup is provided with internal threads, and the bottom cover of the inner cup is provided with dense air holes. The moxibustion health care and treatment device can be used not only for stick moxibustion, but also for floss moxibustion, and can guarantee the heat power to be directly applied on body surface uniformly and stably; the moxibustion temperature can be adjusted conveniently, and dust removal and the fixation is facilitated; meanwhile, the moxibustion health care and treatment device also comprises a moxa container structure, and the moxa container structure is specialized for placing moxa materials to prevent the moxa materials from burning skin during a sandwiched moxibustion process. Therefore, strong security, small and exquisite overall size and carrying convenience are achieved.

The invention belongs to the field of processing of foods and particularly relates to a making method of negative-pressure marinated bacon. The making method is characterized by comprising the following steps: selecting materials, burning skin, washing, cutting, rinsing, loading, marinating, washing, airing, hanging, baking, smoking, airing, then cooling and packaging, wherein the marinating is negative-pressure marinating, namely rough meat after loading is placed into a negative-pressure container and laminated tidily, then, the container is vacuumized till 0.08-0.085MPa, then the container is closed, a vacuum state is always maintained for 4 days for marinating, and the temperature of a marinating environment is 2-6 DEG C. The bacon made by the making method provided by the invention has a clean and sanitary surface and no smoke and dust, and is convenient to eat, safe and healthy; the strip-like shape is complete, the skin color is golden and bright, and lean meat is in rose red; the marinated taste is unique, oily but not greasy, delicious and tasty.

The invention relates to a skin-care composition comprising at least one sun-screening agent, at least one cooling agent, and at least one after-sun repairing agent with a mass ratio of 1-40:1-30:0.1-40. The after-sun repairing agent comprises an extract of at least one material selected from pagodatree flower bud, purslane, sessile stemona root tuber, giant knotweed rhizome, Tokyo violet herb, honeysuckle flower, and Mongolian milkvetch root. The invention also provides a paper towel applying the skin-care composition. The paper towel provided by the invention has the functions of sweat-removing, moisture-absorbing, sun-screening, cooling, and timely reparation for sun-burned skins.

The invention discloses an electronic pain sense measuring pen, which belongs to the field of medical instruments. The electronic pain sense measuring pen is characterized by being manufactured according to a principle that electric stimulation pain is generated when a high-voltage low-current electron impulse acts on human skin. The electron impulse is generated by adopting a piezoelectric effect principle of ceramic crystals. The electronic pain sense measuring pen consists of a pen head, a shell, a trigger switch, a piezoelectricity generator and a conducting wire. The electronic pain sense measuring pen has the advantage of measuring the level of anesthesia to determine the anesthetic effect and guide the anesthesia dosage when applied to intravertebral anesthesia and nerve blocking anesthesia. The electronic pain sense measuring pen avoids inaccurate feeling of pain stimulation of a patient because of the non-constant needling force in a needle punching method, ensures that the measurement result is more accurate, and cannot burn skin and do harm to a body at the same time of safe electric stimulation, thereby eliminating pains of patients, and reducing the probability of infection and blood-source spread diseases.

This invention relates to compositions, methods and delivery systems for application on burns and surrounding tissue wherein said composition comprise ammonium hydroxide (or ammonium bicarbonate) and / or 15-70% volatile short chain mono-alcohols.

The present invention relates to use of hydrogel based on RGD-conjugated alginate with and without addition of nanocellulose and / or fibrin as a novel bioink for 3D Bioprinting of human skin, particularly dermis. RGD-conjugated alginate provides adhesion sites for the human fibroblasts which result in cell adhesion and stretching which contribute to upregulation of genes producing Collagen I. In this invention, RGD-conjugated alginate is used as one of the components of the bioink for 3D bioprinting. Another innovation described herewith is use of coaxial needle when 3D bioprinting with alginate and RGD-modified alginate bioinks. A coaxial needle makes it possible to crosslink the bioink upon 3D bioprinting operation and thus achieve high printing fidelity which is required for high cell viability, proliferation and production of extracellular matrix. In this invention, the novel RGD-modified alginate bioink together with human fibroblasts is 3D bioprinted and the resulting construct shows high cell viability, high cell proliferation, high degree of stretching of fibroblasts and high productivity of Collagen I. The cell bioink construct biofabricated with this invention is ideal for testing cosmetics and active ingredients of skin care products particularly those used for skin regeneration. It is also ideal to be used as skin grafts for skin repair for patients with damaged or burned skin.

The invention discloses self-heating pressing moxibustion and a processing method. The self-heating pressing moxibustion comprises a self-heating pressing moxibustion main body, an adhesive paste surface, a temperature regulation adhesive film and a grid, wherein the self-heating pressing moxibustion main body is connected with a patch body; the adhesive paste surface is machined on the bottom surface of the patch body, a plurality of air holes are machined on the top surface of the moxibustion main body and are divided into at least two partitions; the temperature regulation adhesive film covers the top surface of the moxibustion main body, and more than one tear hole line is machined on the temperature regulation adhesive film; and the grid is arranged in a space for containing a heating agent and divides the space for containing the heating agent into more than two heating agent filling spaces, and the heating agent is filled in each heating agent filling space. A moxibustion head covers outside the grid, and the edge of the moxibustion head is tightly combined with the inner edge of the patch body, the lower edge of the self-heating pressing moxibustion main body or the joint of the patch body and the self-heating pressing moxibustion main body. The heating agent of the self-heating pressing moxibustion does not dip downwards and aggregate without caking, has continuous and stable temperature and can avoid burning skins. The invention is convenient, safe and reliable to use.

The invention belongs to the technical field of medical dressings for repairing burn skin wounds, and provides a double-sustained-release drug-loaded hydrogel dressing with double-layer microspheres entrapped by a semi-interpenetrating network. Acrylic acid is used as a pH-sensitive monomer. The pH / temperature dual-sensitive intelligent hydrogel takes methacrylic acid 2-ethyl ester and oligomeric (ethylene glycol) methyl ether methacrylate as temperature-sensitive monomers, and an anti-inflammatory drug gentamicin sulfate is entrapped; the preparation method comprises the following steps: preparing a calcium alginate core sphere entrapped with bovine serum albumin through a high-voltage electrostatic instillation method, coating the surface of the core sphere with a chitosan shell layer entrapped with an antibacterial drug azithromycin to form a double-layer microsphere, and loading the double-layer microsphere into the hydrogel to obtain the hydrogel dressing capable of precisely and slowly releasing two drugs and one protein. According to the pH / temperature change of a wound surface microenvironment, the hydrogel can achieve accurate controlled release of drugs and improve the utilization rate of the drugs, and is a novel double-sustained-release drug-loaded hydrogel dressing with a semi-interpenetrating network combined double-layer microsphere structure and good comprehensive performance.

The invention provides an antirusting agent, comprising 0.5 to 1.5 percent of sodium molybdate, 0.2 to 4 percent of sodium silicate, 0.5 to 3 percent of hexamethylenetetramine, and 0.05 to 0.5 percent of non-ionic surface active agent peregal, in terms of gross weight of the antirusting agent as 100 percent. The invention also provides a method for applying the antirusting agent. During use, the antirusting agent is mixed with water according to proportion of 1:5-1:10 to prepare antirusting solution; and a work piece is dipped in the antirusting solution for 2 to 30 minutes after phosphating and washing. The antirusting agent can improve the corrosion resistance of the metal surface and improve the performance of humidity isolation and air isolation of a protective layer while ensuring the performance of the original phosphate coating. The antirusting agent can not cause acid mist which pollutes environment, does not contain nitrite, bichromate and other toxic and polluting substances, can not burn skin during use, does not stimulate or damage human body, is safe and reliable, and is easy for operation.

The present invention discloses a shikonin temperature-sensitive aseptic hydrogel, a preparation method and an application thereof, and belongs to the technical field of pharmaceutics. A hydrogel carrier does not use a crosslinking agent, which avoids damages to human body by the crosslinking agent. The preparation method is simple, experimental conditions are mild, no special equipment is needed,investment cost is low, used reagents are conventional reagents, and the shikonin temperature-sensitive hydrogel is convenient for industrial implementation and environmentally friendly. When the shikonin temperature-sensitive hydrogel is used for vaginal administration, the shikonin temperature-sensitive hydrogel has advantages of convenient administration, easy dosage control, uniform distribution, long administration time, etc.; and when the shikonin temperature-sensitive hydrogel is used for burnt skin or inflammatory and damaged skin or mucosal surfaces, the shikonin temperature-sensitive hydrogel has advantages of small stimulation to wound surfaces, easy spreading, uniform distribution, convenient administration, accurate dosage, etc. By loading main medicines and corresponding medicinal auxiliary materials, the shikonin temperature-sensitive hydrogel play moisturizing, repairing, disinfection, sterilization and therapeutic effects, at the same time can form a layer of protective film on surface of lesion, and realizes aseptic maintenance and wound protection for the lesion.

The invention provides a preparation method of dressing for treating burn combined with moist burn cream, which includes (1) dissolving hyaluronic acid and cellulose derivative in distilled water and regulating the pH value to be acidity; (2) adding cross linking agent in the solution in dropwise mode to conduct cross-linking reaction; (3) conducting ethanol precipitation, using ethanol to washing precipitate repeatedly and drying the precipitate in vacuum; and (4) swelling the dried precipitate in water solution containing zinc ions, freezing, drying and pressing the mixture to obtain the slice dressing. The dressing prepared in the method has grease scattering performance when treating the burn combined with the moist burn cream, cannot affect treating effect caused by the fact that the dressing absorbs ointment of the moist burn cream, simultaneously is capable of being attached to the surface of burnt skin to form a loose separation layer which is good in air permeability and capable of absorbing burn surface transduate, can effectively protect and close the burn surface to reduce scab area, and has functions of restraining scar tissue generation and accelerating burn surface union. The dressing enables dressing change to be easy to operate and cannot damage burn surface tissue due to flexibility and globality.

The invention provides a processing method of high-efficient paraquat paste. The paste comprises, by weight percent, 30-45 % of paraquat dichloride salt, being equivalent to 21.74-32.58 % of paraquat cation, 1-6 % of a surfactant alkyl glycoside, 2-8 % of a polyisocyanates curing agent, 2-13 % of a carboxymethylcellulose sodium disintegrating agent, 0.5-3 % of special modified polyether, and the balance being auxiliary agents and water. The finish product is prepared by heating, insulating and stirring. The product has an appearance of dark blue paste, does not flow at a normal temperature, can not only effectively prevent splashing of the paraquat paste to burning skins of human or animals, but also be low in amount of wrong or impulsive swallow because of low fluidity, thereby substantially improving safety of the paraquat and being convenient to transport; and the product can be relatively rapidly dispersed and dissolved, is free of precipitate during standing and substantial in using efficacy.

The invention discloses an optical coherence tomography system for burnt skin. The optical coherence tomography system comprises an optical coherence tomography instrument and a computer control system, wherein the optical coherence tomography instrument acquires an interference signal of necrotic tissue of burnt skin in a target area, and the computer control system analyzes and processes the interference signal, and burn depth and the burn area of the target area are obtained, the three-dimensional image of the target area is synthesized and displayed, spectral interpolation or calibration is not needed in data processing, and the method is simpler and more efficient; at a sample arm, flexible optical focusing is achieved through a zoom lens; and a dispersion compensation lens is added to a reference arm to compensate optical path dispersion and improve axial resolution, so that dispersion compensation is not needed in data processing, and the method is simpler and more efficient, and interference signals of a wave number space can be acquired in a high-fidelity mode in signal acquisition.

The invention relates to a preparation method of a skin patch for treating a skin burn. The preparation method comprises the following steps: respectively obtaining adipose-derived stem cells and allogenic skin matrix; mixing the adipose-derived stem cells with a collagen solution and then inoculating into the allogenic skin matrix, wherein the adipose-derived stem cells are from a patient with the skin burn. By differentiation potential of the adipose-derived stem cells and the stimulation-inducing effect of the allogenic skin matrix, the adipose-derived stem cells are prompted to differentiate into epidermis cells. The adipose-derived stem cells are from the patient with the skin burn, so that the antigenicity is relatively low, and immunological rejection is not easily caused, therefore, the skin repair effect is improved; the target of quickly repairing the skin wound is achieved. In addition, the repairing speed is increased, so that pigment accumulation of the wound part is not easily caused to form a scar and the like; and the pain of the patient is relieved.

The invention discloses a traditional Chinese medicine preparation used for burn. The preparation is composed of materials by weight ratio: 10-30 portions of garden burnet, 10-30 portions of rheum officinale, 20-50 portions of lumbricus, 10-20 portions of Chinese prickly ash, 20-40 portions of licorice. The preparation method comprises the following steps: crushing and mixing all the materials, adding glycerin, making a paste preparation. The medicine preparation is applied on the burned skin and the dosage is flexible according to the burn area; the medicine preparation is usually applied once in two days and one week administration can heal up. The preparation of the invention has good curing effects: in the 157 patients, 143 patients have been cured, 8 patients had obvious effect, 4 patients had effect, two patients had no effect, and the total efficiency has reached 98.7%. The materials in the inventive medicine are all cheap and easily available, which reduces the economic burden of patients.