Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Applications of levorotary oxiracetam and oxiracetam in preparing drugs for preventing or treating coma

A technology of medicine and use, applied in the field of application of levo-oxiracetam and oxiracetam in the preparation of drugs for preventing or treating coma

Active Publication Date: 2014-04-23
CHONGQING RUNZE PHARM CO LTD
View PDF1 Cites 124 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Levo-oxiracetam has not been reported as a single drug application

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Applications of levorotary oxiracetam and oxiracetam in preparing drugs for preventing or treating coma
  • Applications of levorotary oxiracetam and oxiracetam in preparing drugs for preventing or treating coma
  • Applications of levorotary oxiracetam and oxiracetam in preparing drugs for preventing or treating coma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0099] Raw material composition:

[0100] (a) Levoxiracetam (99.5% pure) 200mg / capsule

[0101] (b) Lactose 80mg / capsule

[0102] (c) Microcrystalline cellulose 70mg / capsule

[0103] Taking the preparation of 1000 levoxiracetam capsules as an example, the specific preparation method is: first pass the raw and auxiliary materials through an 80-mesh sieve, weigh the prescribed amount of levoxiracetam, lactose, and microcrystalline cellulose and mix evenly, directly Fill the capsule.

Embodiment 2

[0105] Raw material composition:

[0106]

[0107] Taking the production of 1000 levoxiracetam tablets as an example, the specific preparation method is: first pass the raw and auxiliary materials through an 80-mesh sieve, weigh the prescribed amount of levoxiracetam, starch, and microcrystalline cellulose and mix evenly, add 2% HPMC aqueous solution is used to prepare soft materials, granulate, dry, and granulate, add talcum powder in the prescribed amount to the granules, mix evenly, and compress into tablets.

Embodiment 3

[0109] Raw material composition:

[0110]

[0111] Taking the preparation of 1000 levoxiracetam capsules as an example, the specific preparation method is as follows: first the raw and auxiliary materials are passed through an 80 mesh sieve, and the levoxiracetam, lactose, and carboxymethyl starch sodium are mixed evenly by weighing the prescribed amount, Add 10% PVP ethanol solution to make soft material, granulate, dry, granulate, add prescription amount of talcum powder to the granules, mix evenly, and fill the capsules.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides applications of levorotary oxiracetam and oxiracetam in preparing drugs for preventing or treating coma. Experimental results indicate that levorotary oxiracetam has obvious awaking effect on coma caused by alcoholism, but dextrorotary oxiracetam basically has no effect, and the awaking effect of levorotary oxiracetam is two times of that of dextrorotary / levorotary mixed oxiracetam; levorotary oxiracetam has remarkable awaking effect on comas caused by both trauma and anesthesia.

Description

[0001] The application of the present invention is a divisional application with the application number 2011103766076, the application date of November 23, 2011, and the invention name "levo-oxiracetam and the application of oxiracetam in the preparation of drugs for the prevention or treatment of coma". technical field [0002] The invention relates to levo-oxiracetam and the medical application of oxiracetam, in particular to the application of levo-oxiracetam and oxiracetam in the preparation of drugs for preventing or treating coma. Background technique [0003] Oxiracetam is a nootropic drug synthesized for the first time in 1974 by the Italian Skelebechem Company. The drug was launched in Italy in 1987. Oxiracetam is composed of two isomers (S) - A racemate of oxiracetam ((S)-oxiracetam) and (R)-oxiracetam ((R)-oxiracetam); reports on oxiracetam, which can promote ATP in the brain, promote Acetylcholine synthesizes and enhances the conduction of nerve excitation, which...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/4015A61P25/00
Inventor 叶雷
Owner CHONGQING RUNZE PHARM CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com