8 results about "Corpus callosum" patented technology

[Problem] Conventionally, it has not been possible to simulate brain activity when performing an operation with consideration for long-term memory and short-term memory. [Solution] The problem can be solved by an information processing device 1 comprising: a reception unit 12 that receives information; a feature acquisition unit 131 that acquires a feature set from the information; a transfer unit 132 that performs a transfer process for determining one or more node identifiers paired with a start point condition which matches the feature set and determining a firing node identifier of a node to be fired, which is connected by an edge to a fired node that is identified by each of one or more node identifiers; and a corpus callosum unit 133 that acquires a long-term firing pattern and a short-term firing pattern from one or more firing node identifiers which have been determined by the transfer unit 132, determines, from among an operation paired with a firing pattern that is similar to the long-term firing pattern and an operation paired with a firing pattern that is similar to the short-term firing pattern, an operation which matches an operation condition, and performs the determined operation.

An automatic calculation method of gray-to-white-matter ratio for head computed tomography of patients with cardiac arrest is disclosed and includes an image registration step, a K-means segmentation step, a segmentation refinement step and a GWR calculation step. Measure the gray-white-matter ratio through brain computed tomography early after cardiac arrest to automatically identify the corpus callosum, caudate nucleus, putamen, and posterior branch of the internal brain cyst. It is a 3D three-dimensional structure rather than a manually selected flat circular area to evaluate the effectiveness of predicting neurological prognosis at discharge.

Abnormal activity in the brain can be detected by identifying changes in tissue excitability measured in response to stimulation of fiber tracts such as the corpus callosum. A stimulating electrode contact can apply a stimulation to the fiber tract, which can have one or more terminals to a cortex of a patient's brain, and a recording electrode contact positioned in the fiber tract and / or the cortex to record a tissue excitability response to the stimulation. A controller can receive the tissue excitability response from the at least one recording electrode, identify a parameter of the tissue excitability response, and predict the abnormal activity in the patient's brain based on the parameter being different from a baseline for the parameter. When an abnormal activity is predicted the patient can be alerted to start a therapy and / or a therapy can be applied in closed loop manner by a connected therapy device.

The invention discloses a construction method and application of a prediction model for primary corpus callosum-related pneumonia, and the construction method comprises the following steps: obtaining clinical data and laboratory test results of patients with primary corpus callosum degeneration; carrying out single-factor analysis and screening related factors having statistical significance with the primary corpus callosum degeneration-related pneumonia; the method comprises the following steps: carrying out dimensionality reduction treatment on related factors with statistical significance of primary corpus callosum degeneration-related pneumonia, and carrying out multi-factor logistic regression analysis on the related factors subjected to dimensionality reduction treatment to determine independent related factors of primary corpus callosum degeneration-related pneumonia; and according to the independent related factors of the primary corpus callosum degeneration-related pneumonia, constructing a prediction model of the primary corpus callosum degeneration-related pneumonia. The prediction model constructed by the invention has good prediction capability, and clinicians can identify high-risk patients with primary corpus callosum degeneration related pneumonia as soon as possible and perform intervention and treatment as soon as possible.

A chimeric non-human mammal disease model, wherein (1) at least 30% of all the glial cells in the corpus callosum of the chimeric non-human mammal are human glial cells, and / or (2) at least 5% of all of the glial cells in the white matter of the brain and / or brain stem of the chimeric non-human mammal are human glial cells, and wherein the human glial cells comprise a combination of a first group of human glial cells tagged with a first label and a second group of human glial cells tagged with a second label that is distinguishable from the first label.

The present disclosure relates to the field of medicine, and more particularly to the use of elastase inhibitors in the preparation of medicaments for treating cerebral hypoperfusion. Studies in the disclosed examples have revealed that NE expression is elevated in the corpus callosum of patients with cerebral hypoperfusion. NE can cause damage to oligodendrocytes and white matter lesions. Elastase inhibitors can effectively inhibit NE expression and activity, reducing oligodendrocyte damage. They also mitigate the enzymatic cleavage of NE on the myelin protein CNPase, reducing myelin damage in the corpus callosum and thereby inhibiting white matter lesions.

The invention relates to the technical field of medical diagnosis, and in particular relates to a method for preparing a gene based on NOTCH3 gene c.4738Tgt; the invention discloses a method for non-invasive prenatal evaluation of fetal corpus callosum dysplasia by A mutation. The method comprises the steps of sample collection, plasma separation and free DNA extraction, primer design, targeted sequencing and analysis. Compared with traditional ultrasonic and interventional prenatal diagnosis, the method for noninvasive prenatal diagnosis of fetal corpus callosum dysplasia has the advantages that trauma is small, cost is low, feasibility and operability are high, pregnant women can accept the method easily, the risk of abortion and the like caused by invasive prenatal diagnosis is avoided, and the method is suitable for clinical application. Therefore, the couple with family history can obtain early safe prenatal diagnosis.

A chimeric non-human mammal disease model, wherein (1) at least 30% of all the glial cells in the corpus callosum of the chimeric non-human mammal are human glial cells, and / or (2) at least 5% of all of the glial cells in the white matter of the brain and / or brain stem of the chimeric non-human mammal are human glial cells, and wherein the human glial cells comprise a combination of a first group of human glial cells tagged with a first label and a second group of human glial cells tagged with a second label that is distinguishable from the first label.