Application of isoflavonoids in preparation of medicine for treating multiple sclerosis diseases
A technology for multiple sclerosis, isoflavones, applied in the field of natural medicinal chemistry and medicine
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[0043] Embodiment 1: Application of irisaxanthin and irisin in the preparation of medicines for the treatment of multiple sclerosis
[0044] 1 Experimental drugs and animals
[0045] 1.1 Experimental drugs and preparation: irisxanthin and irisin were dissolved in DMSO to an initial concentration of 0.6 g / ml, and then diluted to 3 mg / ml with normal saline before intraperitoneal injection every day for intraperitoneal injection.
[0046] 1.2 Modeling drugs and preparation: dicyclohexanone oxalyldihydrazone (CPZ, referred to as copper hydrazone), purchased from Sigma Company, mixed with normal rat food at 0.2%, recompressed, and fed for 6-8 weeks;
[0047] 1.3 Experimental animals: C57 male mice, weighing 20-25 g, were purchased from the Experimental Animal Center of Second Military Medical University.
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