A method to extract the duration of cortical resting periods

Abstract

A method for extracting the duration of the cortical rest period, comprising: collecting the electromyographic signals of the hand muscles of the target hand and the opposite hand of the target; preprocessing the collected electromyographic signals; extracting the electromyographic signals in the preprocessed electromyographic signals The peak time point of the interference potential of the transcranial magnetic stimulation; the peak time point of the motor evoked potential is extracted; the energy value of each time point is calculated; the baseline energy value of the EMG signal is calculated; the duration of the cortical rest period is calculated. A fully automatic, single-shot method for extracting the duration of cortical rest periods, which can be used for the extraction of contralateral and ipsilateral cortical rest period durations. The invention is simple and fast in operation, without modifying parameters, and can obtain the duration of a single cortical resting period by inputting electromyographic signals, which can provide a method for transcranial magnetic stimulation to detect the performance of motor zone inhibitory pathways and corpus callosum inhibitory pathways Support, to a certain extent, can promote the application of cortical resting period in brain science research.

Description

technical field [0001] The invention relates to a method for extracting cortex resting period. In particular it concerns a method for extracting the duration of cortical resting periods. Background technique [0002] The principle of transcranial magnetic stimulation is based on Faraday's law of electromagnetic induction. Time-varying electric fields act on the cerebral cortex to generate induced electric fields in the brain, thereby affecting the physiological characteristics of the nerves. It is non-invasive, safe, and can penetrate the skull for stimulation and targeting. In the state of peripheral muscle contraction, the electromyography can record continuous muscle electrical activity. At this time, the single-pulse transcranial magnetic stimulation is applied to the primary motor cortex of the brain corresponding to the contracting muscle. After the stimulus-induced motor-evoked potential waveform, there is a period of muscle electrical activity being suppressed. Thi...

AI Technical Summary

Problems solved by technology

[0003] At present, there are mainly two ways to obtain the cortical resting period. First, the starting point and end point of the cortical resting period are obtained by directly observing the evaluator with the eyes. This method is affected by the subjectivity of the evaluator, and different evaluators The results obtained are different. In addition, the duration of the cortical resting period is generally taken as the average value of multiple tests, so using the eyes to directly observe the cortical resting period for many times will be time-consuming, laborious, and error-prone.

Second, first superimpose and average the EMG signals of the cortical resting period detected multiple times, and observe the starting point and end point of the cortical resting period with the eyes in the superimposed averaged signal, because the cortical resting period is when the muscle contracts However, there are differences in the duration of the cortical resting period collected multiple times within an individual, so the calculation after superposition will shorten the obtained cortical resting period duration, resulting in measurement errors

In addition, the method of measuring the duration of the cortical resting period by superimposing first cannot calculate the change of the cortical resting period in the individual, which affects its scope of use

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