The present invention discloses an electrical stimulation method for observing rat
craniotomy motor cortex with the adjustable waveform and amplitude. The method is characterized in that: the
motor area of the
cerebral cortex is an advanced nerve center for regulating the body
motor function, and, through the downward pathway of the pyramidal and extrapyramidal
system, controls activities of the brain stem and spinal motor neurons, so as to control
muscle movement. Corresponding effects occur after cortical electrical stimulation, experimenters attempt to, through the electrical stimulation of the
motor area of the
cerebral cortex, cause the effect of
body movement, and observe the phenomenon of functional localization of the
motor area of the cortex. The rat is fixed to a stereotaxic apparatus, the bone windows are opened, a cortical electrical stimulation using
microelectrode is performed, and the
electrode is inserted vertically into the position 1.8 mm below the cortex, and adjusted within a range of + / - 200 um so as to cause the maximum movement of the contralateral
forelimb,
facial hair and neck corresponding to the stimulation points. An
electrical stimulator with the adjustable waveform and amplitude is further produced, is capable of accurately completing the experimental observation of electrical stimulation predetermined by experimenters, and provides
technical support for the experiment.