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A brain function localization method based on cortical electroencephalography under median nerve electrical stimulation

A technology of median nerve and cortical EEG, applied in the field of neural engineering, can solve the problem of not distinguishing between short-delay gamma response and long-delay gamma response, and achieve the effect of reducing cognitive load

Active Publication Date: 2022-04-01
NEURACLE TECH CHANGZHOU CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This invention emphasizes the positioning of functional areas by analyzing the event-related synchronization strength or correlation of gamma responses, but does not distinguish between short-delay gamma responses and long-delay gamma responses

Method used

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  • A brain function localization method based on cortical electroencephalography under median nerve electrical stimulation
  • A brain function localization method based on cortical electroencephalography under median nerve electrical stimulation
  • A brain function localization method based on cortical electroencephalography under median nerve electrical stimulation

Examples

Experimental program
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Effect test

Embodiment 1

[0053] like figure 1 As shown, a cortical EEG-based brain function localization method under electrical stimulation of the median nerve comprises the following steps:

[0054] Step S1, giving median nerve electrical stimulation and synchronously collecting cortical EEG data;

[0055] Step S2, preprocessing the collected cortical EEG data;

[0056] Step S3, analyzing the somatosensory evoked potential of the median nerve electrical stimulation, so as to locate the central sulcus;

[0057] Step S4, analyzing the long-time-delay high-frequency gamma nerve response of the electrical stimulation of the median nerve, so as to locate the functional area;

[0058] Step S5, comprehensively analyzing the positioning results of the central sulcus and the functional area, so as to distinguish and locate the sensory functional area and the motor functional area.

[0059] Said step S1 comprises:

[0060] Step 1.1 The frequency of electrical stimulation of the median nerve is less than o...

Embodiment 2

[0079] On the basis of Example 1, in the method for analyzing the gamma response of median nerve stimulation in Example 2, the duration of the baseline segment can vary from 50 milliseconds to 200 milliseconds, and the starting moment of the baseline segment can be 300 minutes before the stimulation. From milliseconds to 50 milliseconds before the stimulus; the duration of the task segment can vary from 50 milliseconds to 200 milliseconds, and the start of the task segment can vary from 50 milliseconds to 300 milliseconds after the stimulus.

[0080] In the method for analyzing the gamma response of the median nerve stimulation, the gamma energy of the baseline segment and the task segment can be selected as a certain frequency interval between 30 Hz and 500 Hz.

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PUM

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Abstract

The invention discloses a brain function positioning method based on cortical EEG under electrical stimulation of the median nerve, and relates to the technical field of neuroengineering, comprising the steps of: giving electrical stimulation to the median nerve, and synchronously collecting cortical EEG data; Preprocessing the electrical data; analyzing the somatosensory evoked potential of the median nerve electrical stimulation to locate the central sulcus; analyzing the long-delay high-frequency gamma nerve response of the median nerve electrical stimulation to locate the functional area; comprehensively analyzing the location of the central sulcus and functional area As a result, sensory and motor functional areas are distinguished and localized. The brain function positioning method based on cortical EEG under the electrical stimulation of the median nerve of the present invention can quickly determine the positions of the central sulcus, the primary sensory cortex and the primary motor cortex by automatically judging the phase of the somatosensory evoked potential by the median nerve electrical stimulation; Electrical stimulation of long-latency gamma response enables stable and reliable localization of sensory and motor functional areas.

Description

technical field [0001] The invention relates to the technical field of neural engineering, in particular to a method for locating brain functions based on cortical electroencephalography under electrical stimulation of the median nerve. Background technique [0002] In neurosurgery, how to accurately, safely, and quickly confirm the important functional areas around the lesion has always been an important issue that surgeons need to face. When important functional areas of the brain are adjacent to or coincident with the lesion, miscutting or overcutting will cause functional damage. Non-invasive techniques such as functional magnetic resonance imaging and transcranial magnetic stimulation can better evaluate the functional area before surgery, but they cannot accurately locate the functional area. The current gold standard for intraoperative cerebral cortex function localization is cortical electrical stimulation, but this method has the risk of inducing epilepsy, and is a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/383A61B5/372A61B5/00
CPCA61B5/7203A61B5/7225A61B5/72A61B5/316
Inventor 陈亮吴泽翰谢涛朱向阳盛鑫军毛颖
Owner NEURACLE TECH CHANGZHOU CO LTD
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