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799 results about "Skull bone" patented technology

Method for modelling a customised helmet for a user for additive manufacturing

PCT designated stage expiredWO2025088277A1HelmetsHelmet coversSoftware engineeringSkull bone
The present invention relates to a method for modelling a customised helmet for a user, the method being characterised in that it comprises carrying out, by data processing means (11) of a first server (1), the steps of: (a) obtaining a three-dimensional representation of a surface of the user's skull; (b) selecting a three-dimensional functional layer model of the helmet from among a plurality of predefined three-dimensional functional layer models according to the three-dimensional representation of the surface of the user's skull; (c) constructing a three-dimensional customised comfort layer model of the helmet that fills the space between the surface of the skull and the functional layer for the selected three-dimensional functional layer model; (d) fusing the selected three-dimensional functional layer model and the constructed three-dimensional customised comfort layer model into a comprehensive helmet model, suitable for additive manufacturing.
Owner:DECATHLON SA

Brain-computer interface module, digital skull implant and integration method and related application thereof

The embodiment of the invention relates to the technical field of brain-computer interfaces, in particular to a brain-computer interface module, a digital skull implant and an integration method and related application of the digital skull implant. The digital skull implant comprises a skull prosthesis and a brain-computer interface module, wherein the brain-computer interface module and the skull prosthesis are integrated; the brain-computer interface module comprises an ultrasonic transducer used for sending ultrasonic signals to the brain and collecting brain echo signals. The brain-computer interface module comprises an ultrasonic transducer used for sending ultrasonic signals to the brain and collecting brain echo signals. The brain-computer interface module is configured to be integrated with a skull or a skull prosthesis. In this way, the implantation structure integrating the brain-computer interface module in the skull form can have good mechanical strength and biocompatibility, complete implantation and wireless design can be achieved, and ultrasonic waves penetrate through the skull to conduct precise stimulation on the brain area.
Owner:GESTALT (CHENGDU) TECHNOLOGY CO LTD

Skull data comparison method and system based on artificial intelligence

The invention discloses a skull data comparison method based on artificial intelligence. The skull data comparison method comprises the following steps: S1, acquiring three-dimensional scanning data of a skull to be detected and a reference skull database; s2, preprocessing the skull data to be detected; s3, multi-dimensional features of the skull to be detected are extracted through the deep learning model; s4, performing similarity comparison on the skull features to be detected and skull features in the reference database to generate a matching degree score; s5, outputting identity information or a morphological analysis result of the target reference skull according to the matching degree score; the invention further provides a skull data comparison system based on artificial intelligence. The skull data comparison system comprises a data acquisition module, a preprocessing module, a feature extraction module, an intelligent comparison module and a visual output module. Compared with the prior art, the method has the advantages that the comparison accuracy is high; the processing speed is high; the application range is wide.
Owner:苟淋

Method, device, equipment, product and storage medium for identifying skull defect by constructing characteristic spectrum through nuclear magnetic image

Belongs to the technical field of biomedical engineering, and discloses a method, a device, equipment, a product and a storage medium for identifying skull defects by constructing a characteristic spectrum through a nuclear magnetic image to solve the problem that a defect area is mistakenly divided into skull areas in existing automatic skull segmentation. Converting the human brain nuclear magnetic image to an anatomical space based on the plurality of anatomical points, and implementing preliminary segmentation to obtain a primary segmentation region of the skull; calculating coordinates of voxel points in the primary segmentation region in an anatomical point coordinate system, establishing a matrix, calculating a plurality of nuclear magnetic gray statistical characteristics of the primary segmentation region, and drawing a characteristic spectrum; and performing multi-condition feature threshold judgment on the feature map to obtain a logic binary map, and extracting a region of which a connected domain is greater than a specified threshold as a skull defect region. According to the method provided by the invention, a plurality of gray features are utilized, the misrecognition of the skull in the prior art is effectively corrected, the method can be further used for judging the filling tissue of the skull defect area, and the skull defect recognition capability can be improved.
Owner:XIAN NEURODOME MEDICAL TECHNOLOGY CO LTD

Preparation method and application of organic-inorganic composite hydrogel with high strength, high inorganic ratio and suitable degradability

The invention discloses a preparation method and application of high-strength, high-inorganic-ratio and degradable organic-inorganic composite hydrogel, and belongs to the technical field of biomedical tissue engineering. The hydrogel is prepared from the following components in percentage by weight: 30 to 70 percent of calcium phosphate nano-cluster and 30 to 70 percent of sodium alginate. The organic-inorganic composite hydrogel is beneficial to proliferation and mineralization of bone cells, and more ideal bone guidance is realized. Experimental results prove that the material has good cytocompatibility, can quickly promote rat skull defect repair (8 mm limit bone injury repair time is shortened to 4 weeks), and has a more remarkable healing effect compared with a contrast autogenous bone graft material with an optimal clinical repair effect. The high-strength organic-inorganic composite hydrogel prepared by the invention is of a single-network structure, shows good mechanical properties, also has excellent degradability matched with tissues, and is beneficial to hard tissue repair.
Owner:ZHEJIANG UNIV

Transcranial magnetic stimulation positioning system based on deep effect brain region

The invention discloses a transcranial magnetic stimulation positioning system based on a deep effect brain region, and the system comprises the steps: obtaining the data of a tested magnetic resonance image, which comprises a resting state functional image and a high-resolution T1 structure image; performing data preprocessing on the function image and the structure image, and establishing an individual space; the deep effect brain region template is converted to an individual space through nonlinear registration, and a target region of interest is defined; calculating functional connections between voxels of the deep effect brain region and the cortical region by adopting a Granger causality analysis method based on wavelet transformation; and screening Top block masses according to the functional connection strength, calculating the gravity centers of the Top block masses, and determining individualized stimulation targets in combination with the skull surface distance. According to the method, spontaneous brain activity function variation of the brain of an individual and the brain signal propagation direction are fully considered, accurate positioning of different individual levels is achieved, relatively stable cortex stimulation targets are obtained, and therefore the clinical curative effect of TMS is optimized.
Owner:HANGZHOU NORMAL UNIVERSITY

Multi-modal fusion-based nuclear magnetic resonance image auxiliary diagnosis method and system

PendingCN120809168AImage enhancementMedical data miningInversion recoveryT1 weighted
The invention relates to the technical field of medical image auxiliary diagnosis, in particular to a nuclear magnetic resonance image auxiliary diagnosis method and system based on multi-modal fusion. The method comprises the following steps: step 1, synchronously acquiring a three-dimensional T1 weighted structure image, a T2 weighted fluid attenuation inversion recovery image and diffusion weighted imaging data of a subject, carrying out spatial registration by taking the T1 weighted image as a reference, and executing skull stripping and gray scale standardization; 2, individualized brain region segmentation is carried out based on a brain anatomical map, the lesion sensitivity weight of each modal is calculated for each segmented brain region, and the weight is obtained by quantifying the following parameters; step 3, extracting multi-modal image features in each brain region; and 4, inputting the fusion features of the whole brain region into a multi-task classifier. The standardization and alignment of the multi-mode MRI image in the space and gray level are realized, and the problems of space mismatch and feature interference among different modes are effectively solved.
Owner:GUANGDONG SUNNICO MEDICAL TECH CO LTD

In-situ printing track planning method

According to the in-situ printing track planning method provided by the invention, an integrated point cloud data processing flow is designed after 3D scanning, so that manual intervention is reduced; the LSCM algorithm and the ARAP algorithm are respectively utilized to carry out plane parameterization and dimension reduction on the three-dimensional triangular mesh so as to reduce the implementation difficulty and improve the path planning efficiency, and the two methods are mutually verified so as to ensure the parameterization effect; solving a grid correspondence problem by utilizing vertex topology uniqueness, and designing a dynamic reasoning mechanism, namely, when fingerprints are not completely unique, gradually deducing to global correspondence through limited vertex corresponding information in a triangle to adapt to uncertainty of defective grid information; a defective skull layering path is integrally generated through input bone tissue parameters and curved surface defect grids, and the structural characteristics of an original skull are simulated. The whole process of the method from point cloud preprocessing to path generation is automatic, intervention is reduced, response is quick, adaptation individuation is improved, and skull tissue function recovery is promoted through bionic design.
Owner:TIANJIN UNIV

A skull repair connection assembly and installation method thereof

The present application discloses a skull repair connection assembly and an installation method thereof, comprising a lower base and an upper cover; the upper cover comprises a cover plate and a one-way bolt; the one-way bolt is fixedly arranged at the lower middle end of the cover plate; a plurality of inclined protrusions are arranged on both sides of the one-way bolt; the lower base comprises a pair of symmetrically arranged card plates; the pair of card plates are fixedly connected by a bent elastic sheet; a cavity for accommodating the one-way bolt is formed between the opposite surfaces of the pair of card plates and the elastic sheet; a plurality of grooves for cooperating with the protrusions are arranged on the side of the card plate close to the cavity; a buckle for engaging the skull or the repair piece is arranged on the side of the lower end of the card plate away from the cavity; a pressing piece for lifting the card plate is arranged on the side of the upper end of the card plate away from the cavity; the protrusions cooperate with the grooves to form a locking structure, so that the lower base and the upper cover are connected and fixed. The installation can be completed in only two steps, and the operation is simple and convenient, and no auxiliary equipment is required.
Owner:SHENZHEN CHANGER MEDICAL TECH CO LTD

Milk-derived pentapeptide for promoting calcium mineral absorption and application thereof

ActiveCN120623307APeptide/protein ingredientsSkeletal disorderOD - Optical densitySkull bone
The invention belongs to the technical field of biology, and particularly relates to milk-derived pentapeptide for promoting calcium mineral absorption and application of the milk-derived pentapeptide. The CPP containing the high-activity peptide fragment is obtained by optimizing a process, and the influence of the CPP on mineral absorption is verified by utilizing a zebra fish model. Then, the pentapeptide GPFPI with calcium absorption promoting activity is screened out from the CPP in combination with peptidomics and a molecular docking technology, functional verification is carried out, it is found that the pentapeptide presents a dose-dependent trend on Ca < 2 + > transport, the Ca < 2 + > transport amount is remarkably increased by 23.23% at 10 mu M, and meanwhile, zebra fish experiments show that intervention of the GPFPI effectively reverses accumulated optical density value reduction caused by dexamethasone, and the effect of inhibiting calcium absorption is achieved. Compared with a manufacturing module, the skull accumulative optical density value of a GPFPI (2-20 mu M) processing group is remarkably increased. It is shown that the synthetic peptide GPFPI can effectively promote Ca < 2 + > transfer and absorption, improve the osteoporosis symptom of zebra fish and increase deposition of calcium in bones.
Owner:HANGZHOU KANGYUAN FOOD SCI & TECH +1

Human body explosive shock wave induced craniocerebral injury dose-effect relationship evaluation device, equipment and medium

The invention provides a device and equipment for evaluating the dose-effect relationship of craniocerebral injury caused by human body explosive shock waves and a medium, and relates to the technical field of craniocerebral injury dose-effect relationship evaluation.The method comprises the steps that firstly, the scale law relationship of explosive shock wave attenuation coefficients of different species is established, and the incidence pressure peak values of the forehead of the human body corresponding to different incidence overpressure duration time are calculated; and then establishing a human body craniocerebral explosion injury 50% survival curve, and evaluating the craniocerebral injury dose-effect relationship of the person to be evaluated based on the curve. According to the evaluation device, by combining experimental animals with different weights and skull thicknesses, high-precision physical head models and other outfield actual explosion experiments, the dose-effect relationship of the craniocerebral injury of the experimental animals is transited to people, the dose-effect relationship of the craniocerebral injury of the human body is established, a craniocerebral injury evaluation system of the human body explosive shock waves is formed, and the complex structure of the craniocerebral of the human body is considered; and the dose-effect relationship of the animal is filtered into the human body, so that the dose-effect relationship of craniocerebral injury when the human body is subjected to explosion impact can be evaluated more accurately.
Owner:TSINGHUA UNIVERSITY

Head model generation method and device, equipment, storage medium and program product

The invention discloses a method, device and equipment for generating a head model, a storage medium and a program product. The method is characterized by comprising the following steps of: receiving and verifying original three-dimensional T1 weighted image data and an original three-dimensional grid model; performing tissue segmentation based on the verified three-dimensional T1 weighted image data and the original three-dimensional T1 weighted image data to obtain a cerebral grey matter mask, a cerebral white matter mask, a scalp mask and a skull mask; performing topological structure repair on the brain grey matter mask and the brain white matter mask to obtain a brain mask; respectively converting the scalp mask, the skull mask and the brain mask into a scalp mesh model, a skull mesh model and a brain mesh model; calculating and applying a spatial transformation matrix from the verified three-dimensional grid model to the scalp grid model, and performing spatial registration and fusion on the scalp grid model, the skull grid model and the brain grid model to obtain a head model; the method has the advantages that the efficiency, precision and robustness of head model generation are effectively improved, and the method has good cross-platform deployment capability.
Owner:GUOCI CLOUD DIGITAL (DEQING) TECHNOLOGY CO LTD

Bone cement injection device for skull repair

The invention relates to a bone cement injection device for skull repair. The bone cement injection device comprises an outer sheath tube, a separate injection structure and an outer push rod, a pushing channel extending in the axial direction is formed in the outer sheath tube, the tube wall of the outer sheath tube is provided with a first hole group and a second hole group which are symmetrically distributed by 180 degrees in the circumferential direction, and each hole group comprises a plurality of via holes arranged at equal intervals in the axial direction; the two symmetrically-arranged separated injection structures are arranged corresponding to the first hole set and the second hole set respectively, each separated injection structure comprises a separated injection pipe, the separated injection pipe is inserted into the pushing channel, a perfusion channel extending in the axial direction is arranged in the separated injection pipe, the near end of the perfusion channel is through, and the far end of the perfusion channel is closed; the rigid contact pins are arranged at equal intervals in the axial direction of the separate injection pipe and penetrate through the side wall of the separate injection pipe at the same circumferential angle, and the inner end of each contact pin is communicated with the perfusion channel. The repairing block can be effectively filled with bone cement, and the effect after skull repairing is improved.
Owner:XUANWU HOSPITAL OF CAPITAL UNIV OF MEDICAL SCI

Cranial ultrasonic standard plane imaging and automatic detection and display method for abnormal regions

ActiveUS12329567B2Image enhancementImage analysisScan ultrasoundSkull bone
The present disclosure relates to the field of ultrasonic detection, in particular to a craniocerebral ultrasonic standard plane imaging and automatic detection and display method for abnormal regions. The following technical solution is adopted: contour detection is performed on the scanned ultrasound images the skull to construct a skull surface model, and the standard planes in ultrasound images are identified and extracted according to the skull surface model. The symmetry of the standard planes in ultrasound images is used to compare the similarity, so as to obtain the abnormal regions for segmentation and display. The advantages of the present disclosure are as follows: the skull surface model is constructed by detecting the cranial edge, and the coordinate system is established based on this model, thereby the standard planes in ultrasound images can be quickly identified from the scanned ultrasound images.
Owner:SHANTOU INST OF UITRASONIC INSTR CO LTD

Skull defect repair structure based on peek skull repair material structure reconstruction

The invention relates to the technical field of peek skull defect repair, in particular to a skull defect repair structure based on structural reconstruction of a peek skull repair material, which comprises a repair patch, a plurality of hourglass-shaped pore channels are formed in the surface of the repair patch, the diameter of the port of a horn-shaped concave groove is larger than that of the tail of the horn-shaped concave groove, the diameter of the port is 1.5 mm, the diameter of the tail of the horn-shaped concave groove is 0.05 mm, and the diameter of the hourglass-shaped pore channels is 1.5 mm. The hourglass-shaped hole channel is designed to be in an hourglass shape with two wide ends and a slender channel, the contact area between the two ends of the hole channel and healthy skull tissue is increased, growth, climbing and combination of granulation tissue are facilitated, meanwhile, attachment, adhesion and healing of soft tissue inside and outside a growth promoting layer repairing material are facilitated, the integration degree of the implant is further improved, and the survival rate of the implant is increased. And the outer surface of the PEEK is covered with the convex structures, so that the contact area between the PEEK material and tissues can be increased, the growth and combination of the tissues are facilitated, and individualized design conforming to aesthetic plastic surgery, thickening design for supplementing temporal muscle atrophy space and mutual embedding of the PEEK material and the skull are carried out.
Owner:THE 960TH HOSPITAL OF THE CHINESE PEOPLES LIBERATION ARMY JOINT LOGISTICS SUPPORT FORCE

Simulation method for brain cumulative injury under action of multiple shock waves

The invention provides an analogue simulation method for accumulated craniocerebral injury under the action of multiple shock waves, and relates to the technical field of data processing. The method comprises the following steps: constructing an explosive shock wave model; constructing a head geometric model; the brain, the cerebellum and the brainstem in the solid area are represented through a Mooney Rivlin model; representing the skin, muscles and skull in the solid area through a linear elastic constitutive model; the cerebrospinal fluid in the fluid area is represented through the fluid dynamic model; coupling the fluid region and the solid region through an embedded boundary method; calculating the explosion impact pressure when the explosion impact waves of each turn are transmitted to the head through an explosion impact wave model; through a finite element analysis method, accumulated skull displacement, skull acceleration, skull stress, skull strain and intracranial pressure under the action of each turn of explosion shock waves are determined, and a brain accumulated injury value is calculated.
Owner:THE SIXTH MEDICAL CENT OF THE CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL +1

Non-imaging TFUS systems

Systems and methods using non-imaging transcranial focused ultrasound (tFUS) systems are described. Non-imaging annular and matrix probes with low element counts are used in the systems. In an embodiment, an infrared-based system is used to gather the ultrasound's position information on the scalp. The position information is used to simulate the spatial distribution of the ultrasound field of the ultrasound probes. The simulation output is overlaid with pre-procedure MRI data and displayed to a clinician. Measurements on the MRI data are used to compensate the beam formation for the acoustic behavior of the skull so that a desirable tFUS focal region is achieved. In a different embodiment, an optical system is used for gathering positional information.
Owner:SANMAI TECH PBC

Brain image region label generation method based on standard space inverse deformation reflection

The invention discloses a brain image area label generation method based on standard space inverse deformation reflection, and relates to the technical field of medical image processing and computer vision. The method comprises the following steps: performing skull stripping and resampling preprocessing on an individual space target brain image, performing rigid, affine and nonlinear cascade registration on the preprocessed brain image and a standard space template, and solving a forward deformation field and an inverse deformation field; calling an inverse deformation field to reversely propagate standard space anatomical atlas labels to an individual space, and resolving label conflicts to obtain an initial label graph; generating each modal coarse label graph through the registration matrix, and performing weighted fusion according to a confidence coefficient weight to obtain a consistent coarse label set; quality control is executed based on anatomy prior, an individualized label is obtained after topological repair, and finally a label, metadata and an uncertainty evaluation report are exported. According to the method, automation and standardization of brain image tag generation are realized, and the accuracy, consistency and generalization ability of tags are improved.
Owner:CHONGQING UNIV OF TECH

Brain-computer interface signal enhancement and evaluation method fusing physical information

The invention discloses a brain-computer interface signal enhancement and evaluation method fusing physical information. The method comprises the following steps: firstly, based on an individual structure magnetic resonance image, constructing a personalized six-layer brain tissue anatomical model comprising a cortex, a white matter, cerebrospinal fluid, a dura mater, a skull and a scalp, and endowing differentiated conductivity parameters; secondly, neuroelectrophysiology priori knowledge such as neurodynamics and white matter anisotropic conduction is converted into a representation rule which can be learned by a neural network; then, the rules are systematically embedded into a physical information neural network in a differentiable physical constraint form, including a cortical neurodynamic equation residual error, a volume conduction equation residual error of each layer and an interlayer interface continuity constraint; and finally, training a network by using the scalp electroencephalogram signals, and jointly outputting high-fidelity intracranial electroencephalogram signals and multi-modal neurophysiological information by minimizing a loss function containing reconstruction and physical constraints. According to the method, the fidelity, the physical rationality and the clinical interpretability of signal enhancement are effectively improved.
Owner:SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI

Craniofacial restoration method based on diffusion model

PendingCN120543750AImage enhancementImage analysisCraniofacialSkull bone
The invention discloses a craniofacial restoration method based on a diffusion model, and the method comprises the steps: S1, collecting a three-dimensional medical image of a head, carrying out the standardization processing and biological information labeling of the three-dimensional medical image, and obtaining a skull-craniofacial data set; s2, training a PiPNet network by using the craniofacial image marked with the craniofacial key structure mark points to obtain a craniofacial mark point recognition network; s3, constructing a craniofacial restoration network, and training the craniofacial restoration network by using the skull-craniofacial data set to obtain a craniofacial restoration model; and S4, inputting the skull image and the corresponding biological information into the craniofacial restoration model, and outputting a restored craniofacial image. According to the method, personal identity features are comprehensively captured by integrating multi-modal information; a diffusion model is used as a backbone network, the dependence of a traditional method on training data distribution is broken through, and the quality of a recovery result is remarkably improved. And meanwhile, an editable text prompt mechanism is introduced, so that the uncertainty of skull-face mapping is effectively reduced.
Owner:SICHUAN UNIV

Device for restoring the integrity of the cranial bones, particularly of the non-resorbable type

The present invention concerns a device (1) for restoring the integrity of the cranial bones, particularly of the non-resorbable type, comprising a plate body (3) in turn comprising a central body (5) and at least one peripheral portion (71), wherein said at least one peripheral portion (71) comprises fastening means (72) for fastening the device itself to the cranial bone (100), and wherein said cranial fixation device (1) comprises, at said central body (5), at least one insertion portion (50) protruding in a direction substantially orthogonal to said plate body (3) and which is configured to be inserted within a hole (102), drilled in the skull (100) of a patient, wherein said insertion portion (50) comprises a trabecular structure (51), suitable for stimulating bone regrowth and osseointegration of the device itself.
Owner:MT ORTHO SRL

Splicing skull repairing system

The utility model relates to the technical field of skull repairing, in particular to a splicable skull repairing system which comprises a first skull repairing piece, a second skull repairing piece and a plurality of connecting assemblies used for connecting the first skull repairing piece and the second skull repairing piece to the skull of the human body, and the first skull repairing piece and the second skull repairing piece are arranged in an up-down spaced mode. The first skull repairing piece comprises a plurality of first splicing strips which are arranged side by side in an abutting mode, the second skull repairing piece comprises a plurality of second splicing strips which are arranged side by side in an abutting mode, and the arrangement direction of the second splicing strips and the arrangement direction of the first splicing strips are staggered; a plurality of convex tongues are arranged on the second skull repairing sheet in an array mode, and a plurality of clamping grooves are formed in the first skull repairing sheet in an array mode; and the second skull repairing sheet is connected with the first skull repairing sheet through the clamping matching of the convex tongue and the clamping groove. The skull repair block has the advantages that the risk that the skull repair block collapses when bearing impact is reduced, the strength of the spliced skull repair block is improved, a patient is protected, the operation time is shortened, and the cost and the postoperative infection rate are reduced.
Owner:HUNAN JINBAIWEI MEDICAL TECH CO LTD +1

Composite bone repair material, preparation method and application

The invention relates to a composite bone repair material, a preparation method and application, the preparation method comprises the following steps: immersing silkworm cocoons in a soap salt solution for degumming, drying to prepare degummed silk, dissolving the degummed silk in a lithium bromide solution, dialyzing for desalting, and concentrating to obtain a regenerated silk protein solution; mixing the regenerated silk fibroin solution with a gelatin solution to obtain a gel solution; mechanically shaking the gel solution, so that the gel solution is uniformly mixed, uniformly distributed bubbles are formed in the gel solution, and a silk protein / gelatin gel block is obtained; soaking and cleaning the silk protein / gelatin gel block in an ammonium sulfate solution to obtain silk protein / gelatin cross-linked gel; and freeze-drying the fibroin / gelatin cross-linked gel to obtain the fibroin / gelatin composite material. The composite bone repair material has the advantages that the composite bone repair material has a bionic porous structure, has excellent mechanical properties and also has good biocompatibility and osteogenic activity. The material can be applied to filling and regeneration repair of skull defects of the orthopedics department, the oral cavity, the plastic surgery (maxillofacial) and the neurosurgery department, and has high industrial production and clinical application prospects.
Owner:SHANGHAI REGE-INNOVATION MEDICAL TECHNOLOGY CO LTD

Method for the analysis of radiographic images, and in particular lateral-lateral teleradiographic images of the skull, and relative analysis system

A computer-implemented method for the geometric analysis of digital radiographic images, in particular lateral-lateral teleradiographs of the skull, uses a radiographic system that includes a display unit and processing system connected to the display unit. The radiographic system is configured for analyzing digital radiographic images.
Owner:CEFLA SOC COOP

Bone surface bidirectional three-dimensional reconstruction and editing method and device, computer equipment and medium

The invention relates to the technical field of three-dimensional shape modeling and reconstruction, and discloses a bone surface bidirectional three-dimensional reconstruction and editing method and device, computer equipment and a medium, the method comprises the following steps: obtaining a plurality of multi-modal facial skull three-dimensional data, and obtaining a three-dimensional facial grid and a three-dimensional skull grid based on the multi-modal facial skull three-dimensional data, then, a dense ray matching technology of face-skull topological consistent registration is adopted to obtain a dense control point corresponding relation and a topological consistent face grid; based on a preset face-skull structure mapping relation, mapping the face grid and the three-dimensional skull grid which are topologically consistent, and establishing a dense tissue thickness vector field; on the basis of the dense control points and the dense tissue thickness vector field, a bone surface-tissue joint deformable model is constructed to conduct bone surface bidirectional three-dimensional reconstruction, finally bone surface bidirectional three-dimensional editing is conducted on the basis of a bone surface bidirectional three-dimensional reconstruction result, and the precision and individuation level of three-dimensional bone surface reconstruction are remarkably improved.
Owner:INST OF AUTOMATION CHINESE ACAD OF SCI

3D printing PCL / nHA combined bionic glycopeptide hydrogel stent for replacement of infected bone defect and preparation method of 3D printing PCL / nHA combined bionic glycopeptide hydrogel stent

The invention discloses a 3D printing PCL / nHA combined bionic glycopeptide hydrogel scaffold for infected bone defect substitution and a preparation method thereof, and belongs to the field of biomedical materials. The scaffold comprises a 3D printed PCL / nHA porous scaffold, the 3D printed PCL / nHA porous scaffold is provided with three-dimensional interconnected micro-channels, the mass percentage of nHA is 10-30wt%, the scaffold is further filled with a bionic glycopeptide hydrogel layer formed by mixing methylacryloylated gelatin, aldehyde bletilla striata polysaccharide, antibacterial peptide and a photoinitiator according to the ratio of 10: 4: 2: 1 and carrying out ultraviolet irradiation polymerization, phenyl lithium phosphate is adopted as the photoinitiator, and the bionic glycopeptide hydrogel layer is a bionic glycopeptide hydrogel layer. And 3D printing process parameters are accurately controlled. The preparation method comprises the steps of PCL / nHA porous scaffold preparation, pretreatment, finished product treatment, bionic glycopeptide hydrogel solution preparation, filling polymerization and the like. The scaffold disclosed by the invention integrates excellent mechanical properties, biocompatibility, antibacterial and anti-inflammatory capabilities and strong bone induction biological activity, provides an ideal material for repairing infected bone defects, and effectively overcomes many defects of a traditional skull repairing material.
Owner:ZHENGZHOU UNIV

Guided ultrasound transcranial focusing method and device based on combination of k-space pseudo-spectrum method and angular spectrum method

The invention discloses a guided ultrasound transcranial focusing method and device based on the combination of a k-space pseudo-spectrum method and an angular spectrum method, and relates to the field of transcranial focused ultrasound simulation, and the method comprises the steps: obtaining a CT image of a target skull; calculating acoustic parameters of the CT image of the target skull; according to the CT image and the acoustic parameters of the target skull, applying a k-space pseudo-spectrum method to simulate propagation of ultrasonic waves before the ultrasonic waves enter the target skull, and obtaining initial ultrasonic field distribution before the ultrasonic waves enter the skull; according to the initial ultrasonic field distribution, applying an angular spectrum method to simulate propagation of ultrasonic waves before the ultrasonic waves enter the target skull, and obtaining target ultrasonic field distribution passing through the skull. According to the method, the k-space pseudo-spectrum method and the angular spectrum method are innovatively combined, and the calculation efficiency of transcranial ultrasonic simulation is improved while the focusing precision of the transcranial ultrasonic simulation is ensured.
Owner:BEIHANG UNIV

Macro-microstructure integrated design method for skull patch with bionic vibration isolation function

The invention provides a skull patch macro-microstructure integrated design method with a bionic vibration isolation function. The skull patch macro-microstructure integrated design method comprises the steps that a skull three-dimensional model is reconstructed based on CT data; designing the geometrical shape of a skull patch according to a defect area in the skull three-dimensional model; establishing a finite element analysis model, and designing the overall structure of the skull patch based on a topological optimization method to obtain overall truss structures of the skull patch and through holes between the truss structures; the through holes between the truss structures are filled with bionic vibration isolation structures; and filling the bionic vibration isolation structure by using a lattice structure to obtain the skull patch macro-micro structure with the bionic vibration isolation function. After the skull patch designed by the invention is implanted into a body, the skull patch has a good vibration isolation function, so that internal tissues of the brain are protected.
Owner:HANGZHOU YINGPAIKE MEDICAL TECHNOLOGY CO LTD

Newborn head shape correcting pillow

InactiveCN120324166ANursing bedsMedical transportCRANIAL DEFORMITYOsteoblast
The invention belongs to the technical field of medical supplies, and discloses a newborn head shape correcting pillow which comprises a pillow body, a positioning seat is arranged at the top end of the pillow body, an air conveying port is fixed to the outer portion of the positioning seat, a self-adaptive mechanism is installed at the bottom end of the positioning seat, a traction mechanism is arranged in the positioning seat, and a measuring mechanism is installed in the pillow body. Through cooperation of micro motors, a winding drum, an elastic band and other structures, the device can make a flexible silica gel head ring sleeve the forehead of a newborn, the multiple sets of micro motors are started to drive the winding drum to wind the elastic band, the traction direction is cooperatively controlled through the double motors, vector adjustment in a three-dimensional space is achieved, and the device accurately acts on a skull malformation area; the intermittent traction force can activate osteoblast activity of skull sutures, increase the local bone deposition rate and correct the head shape of the newborn, so that the aim of conveniently improving the correction efficiency of the device is achieved.
Owner:WUHAN XINTA MEDICAL TECH CO LTD

Antibacterial bioactive glass composite material for skull defect repair and preparation method thereof

The invention discloses an antibacterial bioactive glass composite material for skull defect repair and a preparation method thereof, and relates to the technical field of bioactive glass materials. The antibacterial bioactive glass composite material for skull defect repair is prepared from the following raw materials in parts by weight: 8 to 15 parts of collagen, 45 to 55 parts of bioactive glass, 20 to 30 parts of hydroxyapatite, 5 to 8 parts of a toughening agent, 1 to 2 parts of an antibacterial agent and 150 to 250 parts of deionized water. The antibacterial bioactive glass composite material for skull defect repair prepared by the invention has excellent bending strength and antibacterial property.
Owner:HUBEI SHUANGXING PHARMA CO LTD