389 results about "Skull bone" patented technology

The embodiment of the invention relates to the technical field of brain-computer interfaces, in particular to a brain-computer interface module, a digital skull implant and an integration method and related application of the digital skull implant. The digital skull implant comprises a skull prosthesis and a brain-computer interface module, wherein the brain-computer interface module and the skull prosthesis are integrated; the brain-computer interface module comprises an ultrasonic transducer used for sending ultrasonic signals to the brain and collecting brain echo signals. The brain-computer interface module comprises an ultrasonic transducer used for sending ultrasonic signals to the brain and collecting brain echo signals. The brain-computer interface module is configured to be integrated with a skull or a skull prosthesis. In this way, the implantation structure integrating the brain-computer interface module in the skull form can have good mechanical strength and biocompatibility, complete implantation and wireless design can be achieved, and ultrasonic waves penetrate through the skull to conduct precise stimulation on the brain area.

The invention discloses a method, device and equipment for generating a head model, a storage medium and a program product. The method is characterized by comprising the following steps of: receiving and verifying original three-dimensional T1 weighted image data and an original three-dimensional grid model; performing tissue segmentation based on the verified three-dimensional T1 weighted image data and the original three-dimensional T1 weighted image data to obtain a cerebral grey matter mask, a cerebral white matter mask, a scalp mask and a skull mask; performing topological structure repair on the brain grey matter mask and the brain white matter mask to obtain a brain mask; respectively converting the scalp mask, the skull mask and the brain mask into a scalp mesh model, a skull mesh model and a brain mesh model; calculating and applying a spatial transformation matrix from the verified three-dimensional grid model to the scalp grid model, and performing spatial registration and fusion on the scalp grid model, the skull grid model and the brain grid model to obtain a head model; the method has the advantages that the efficiency, precision and robustness of head model generation are effectively improved, and the method has good cross-platform deployment capability.

The invention discloses a brain image area label generation method based on standard space inverse deformation reflection, and relates to the technical field of medical image processing and computer vision. The method comprises the following steps: performing skull stripping and resampling preprocessing on an individual space target brain image, performing rigid, affine and nonlinear cascade registration on the preprocessed brain image and a standard space template, and solving a forward deformation field and an inverse deformation field; calling an inverse deformation field to reversely propagate standard space anatomical atlas labels to an individual space, and resolving label conflicts to obtain an initial label graph; generating each modal coarse label graph through the registration matrix, and performing weighted fusion according to a confidence coefficient weight to obtain a consistent coarse label set; quality control is executed based on anatomy prior, an individualized label is obtained after topological repair, and finally a label, metadata and an uncertainty evaluation report are exported. According to the method, automation and standardization of brain image tag generation are realized, and the accuracy, consistency and generalization ability of tags are improved.

The invention discloses a brain-computer interface signal enhancement and evaluation method fusing physical information. The method comprises the following steps: firstly, based on an individual structure magnetic resonance image, constructing a personalized six-layer brain tissue anatomical model comprising a cortex, a white matter, cerebrospinal fluid, a dura mater, a skull and a scalp, and endowing differentiated conductivity parameters; secondly, neuroelectrophysiology priori knowledge such as neurodynamics and white matter anisotropic conduction is converted into a representation rule which can be learned by a neural network; then, the rules are systematically embedded into a physical information neural network in a differentiable physical constraint form, including a cortical neurodynamic equation residual error, a volume conduction equation residual error of each layer and an interlayer interface continuity constraint; and finally, training a network by using the scalp electroencephalogram signals, and jointly outputting high-fidelity intracranial electroencephalogram signals and multi-modal neurophysiological information by minimizing a loss function containing reconstruction and physical constraints. According to the method, the fidelity, the physical rationality and the clinical interpretability of signal enhancement are effectively improved.

The invention relates to the technical field of three-dimensional shape modeling and reconstruction, and discloses a bone surface bidirectional three-dimensional reconstruction and editing method and device, computer equipment and a medium, the method comprises the following steps: obtaining a plurality of multi-modal facial skull three-dimensional data, and obtaining a three-dimensional facial grid and a three-dimensional skull grid based on the multi-modal facial skull three-dimensional data, then, a dense ray matching technology of face-skull topological consistent registration is adopted to obtain a dense control point corresponding relation and a topological consistent face grid; based on a preset face-skull structure mapping relation, mapping the face grid and the three-dimensional skull grid which are topologically consistent, and establishing a dense tissue thickness vector field; on the basis of the dense control points and the dense tissue thickness vector field, a bone surface-tissue joint deformable model is constructed to conduct bone surface bidirectional three-dimensional reconstruction, finally bone surface bidirectional three-dimensional editing is conducted on the basis of a bone surface bidirectional three-dimensional reconstruction result, and the precision and individuation level of three-dimensional bone surface reconstruction are remarkably improved.

The invention discloses an antibacterial bioactive glass composite material for skull defect repair and a preparation method thereof, and relates to the technical field of bioactive glass materials. The antibacterial bioactive glass composite material for skull defect repair is prepared from the following raw materials in parts by weight: 8 to 15 parts of collagen, 45 to 55 parts of bioactive glass, 20 to 30 parts of hydroxyapatite, 5 to 8 parts of a toughening agent, 1 to 2 parts of an antibacterial agent and 150 to 250 parts of deionized water. The antibacterial bioactive glass composite material for skull defect repair prepared by the invention has excellent bending strength and antibacterial property.

The invention relates to the technical field of skull drilling equipment, in particular to an intelligent skull drilling device and method based on force-position feedback control, and the intelligent skull drilling device based on force-position feedback control comprises a shell which is provided with an equipment cavity; the supporting assembly comprises a plurality of supporting mechanisms, an adsorption mechanism and a vibration reinforcing mechanism, and the supporting mechanisms are arranged around the shell; the drilling assembly comprises a driving mechanism, a feeding mechanism and a drill bit; and the brake assembly comprises a photoelectric detection mechanism and a brake mechanism. According to the invention, the organic combination of stable support, accurate control and active protection is realized, and the operation error and intraoperative risk are effectively reduced.

The invention belongs to the technical field of mouse neuroscience research, and relates to a multi-modal mouse virtual reality and nerve recording integrated system based on skull anchoring, which comprises a skull anchoring basic support, a binocular miniature VR display module, a multi-modal fixed expansion frame and a behavior and power supply platform. According to the invention, the skull screw is used as a unique space reference, accurate limiting of the head is realized through rapid butt joint of the MMA and the external fixing rod, and rapid plugging and coordinate multiplexing of equipment for two-photon imaging, optical genetic stimulation and the like are realized in combination with an M2 anchoring hole preset in the MMA; the total mass of the whole machine is strictly controlled within 3.2 g; the optical system provides panoramic visual stimulation with a horizontal field angle of 140 degrees, completely covers a key binocular vision area on the top of the mouse head, and supports high-order cognitive task paradigms such as complex ecological visual navigation, spatial memory and social interaction.

The invention relates to the technical field of image processing, in particular to a skull defect area intelligent segmentation method based on a medical image. The method comprises the following steps: acquiring a to-be-analyzed image and a template image of the brain; constructing a window by taking each pixel point as a center; obtaining a difference evaluation index of two windows with the same positions of the to-be-analyzed image and the template image; acquiring a skeleton line in the template image, acquiring pixel points corresponding to the pixel points in the template image on the skeleton line, and then obtaining included angles of the pixel points in the to-be-analyzed image; acquiring a neighborhood window of each window of the to-be-analyzed image, and judging whether each window is an initial abnormal window or not; judging whether each initial abnormal window is a suspected skull defect window or not; judging whether the suspected skull defect window is an abnormal window or not according to the gray level change condition of the pixel points in the suspected skull defect window; and segmenting the to-be-analyzed image according to the abnormal window to obtain a skull defect area. According to the method, the craniocerebral defect area can be effectively segmented.

The invention belongs to the technical field of medical instruments, and discloses a surgical instrument for building a traumatic brain injury mouse model.The surgical instrument comprises a tube blade, a limiter, a holding piece and a vacuum device, the tube blade is used for rotationally cutting into brain tissue of a mouse, the limiter is movably installed on the tube blade in the axial direction of the tube blade, and the vacuum device is arranged on the holding piece; the limiting device is used for abutting against the skull of the mouse, the holding piece is provided with an airflow channel, one end of the holding piece is connected with the pipe blade, one end of the airflow channel is communicated with the pipe blade, and the vacuum device is connected to the other end of the holding piece and connected with the other end of the airflow channel. According to the surgical instrument for building the traumatic brain injury mouse model, the problems that an injury area is uncontrollable and a focus area is difficult to quantify and unify in the current traumatic brain injury mouse model building process can be solved, so that the success rate and efficiency of model building are improved to the maximum extent.

The application discloses a low-intensity focused ultrasound transducer positioning regulation method, device and equipment, belongs to the technical field of transcranial focused ultrasound nerve regulation, and comprises the following steps: acquiring a head CT image of a PACS system; setting a skull layer HU threshold value and performing segmentation and extraction, reconstructing a three-dimensional skull contour model based on the segmentation and extraction result; screening transducer center point arrays outside the three-dimensional skull contour model; performing simulation selection of ultrasonic sound pressure and transducer positioning; performing focused ultrasound stimulation based on the transducer positioning result, checking the effects of the ultrasonic sound field and the spatial sound field of the positioned transducer point in the target area; and constructing a thermal effect temperature field under the focused ultrasound stimulation based on the sound field analysis of the corresponding target area, and verifying the safety of the positioned transducer. The application can calculate an optimal ultrasonic action path according to multiple ultrasonic frequencies, intensities, duty cycles and pulse repetition intervals required, and meets the needs of clinical use.

A histotripsy therapy system configured for the treatment of brain tissue is provided, which may include any number of features. In one embodiment, the system includes an ultrasound therapy transducer, a drainage catheter, and a plurality of piezoelectric sensors disposed in the drainage catheter. The ultrasound therapy is configured to transmit ultrasound pulses into the brain to generate cavitation that liquefies a target tissue in the brain. The drainage catheter is configured to detect the ultrasound pulses. An aberration correction algorithm can be executed by the system based on the ultrasound pulses measured by the drainage catheter to automatically correct for an aberration effect caused by the ultrasound pulses passing through a skullcap of the patient.

The invention relates to the technical field of orthopedic medical instruments, in particular to a skull traction operation auxiliary device and a control method thereof. The traction bed body provides a lying position / prone position for a patient, the skull traction bow is fixed to the head of the patient and used for traction, and the flexible traction arm is arranged on one side of the traction bed body and used for being connected with the skull traction bow. The flexible traction arm is provided with a connecting rod used for installing the skull traction bow, and the connecting rod is provided with an intelligent control stopwatch used for being matched with the skull traction bow. The auxiliary device for the skull traction operation has the advantages that the situation that the cervical curvature is inconvenient to adjust in the operation is improved, and the operation convenience of the auxiliary device for the skull traction operation is improved.

The utility model discloses a bone conduction hearing aid which comprises a host, one end of the host is fixedly connected with a supporting column, the top end of the supporting column is fixedly connected with a connecting sleeve, one end of the host is fixedly connected with an adjusting mechanism, the connecting sleeve is sleeved on the end portion of a spectacle frame, and the bone conduction hearing aid is limited and fixed through the spectacle frame. The main machine and the spectacle frame cannot clamp and extrude each other, the ear pain problem is avoided, meanwhile, the bone conduction sound transmission device can be smoothly attached to the skull or the facial bone through the downward concave part, normal work of the bone conduction sound transmission device is guaranteed, and the sound transmission efficiency is improved. The position of the bone conduction sound conducting device in the vertical direction can be adjusted through the connecting column, meanwhile, the position of the bone conduction sound conducting device in the horizontal direction can be adjusted under the action of the rotating shaft, the bone conduction sound conducting device can be adjusted to the proper position through the two different adjusting modes, and therefore the use requirements of different patients are met; the use by different patients is convenient.

This invention relates to the field of biomedical technology, specifically to a biomimetic piezoelectric scaffold for promoting bone repair, its preparation method, and its applications. The biomimetic piezoelectric scaffold provided by this invention is produced by electrospinning PLLA into oriented nanofibers, and then modifying the fiber surface with nano-hydroxyapatite. To enhance the adhesion of hydroxyapatite to the fiber surface, a polydopamine layer is modified between the two as a connecting layer, ultimately resulting in a biomimetic piezoelectric scaffold with high porosity, good osteointegration, and osteogenic promoting effects. This scaffold exhibits good bone regeneration promoting effects in in vitro MSC recruitment, osteogenic differentiation experiments, and repair of skull bone defects in rats.

The invention relates to a nickel-titanium alloy stent for limiting brain bulging and flap sinking after skull flap removal and a preparation method of the nickel-titanium alloy stent, and relates to the field of biomedical materials, the stent is of an elastic net-shaped structure which is arranged according to the radian of a missing flap on a bone window and is provided with a plurality of reserved gaps; the stress deformation pressure of the bracket ranges from 103.085 kPa to 103.285 kPa, and the stress deformation pressure of the bracket ranges from 103.085 kPa to The stent comprises a plurality of polygonal grid units which are uniformly distributed, the plurality of polygonal grid units are connected to form a net-shaped structure, and pores in the middles of the polygonal grid units are reserved gaps; and each polygonal grid unit consists of a plurality of S-shaped edge wires which are connected end to end. In a deboning decompression operation, the nickel-titanium alloy stent provided by the invention is placed on a bone window to solve the problems of early-stage brain bulging and later-stage skin flap sinking after a skull flap is removed; the prepared nickel-titanium alloy stent is excellent in mechanical property, high in biological safety and high in clinical adaptability.

A system and method for high-resolution, non-invasive characterization of a cranial cavity and its contents through an intact skull.

A machine and process for automatically determining the optimal dimensions and configurations of probes to be placed in the brain for either recording brain activity or for the delivery of electrical current, chemicals, liquids or cells. This system uses three dimensional stereotactic planning and provides an optimization for hardware to be implanted based both on available manufactured devices as well as devices that may possibly need to be manufactured specifically for individual use. Systems for determining the thickness of the skull bone to be removed and for the optimal anchoring devices placed to hold such probes and electrodes temporarily in place are also described. A real time system for detecting errors based on prior calculated trajectory lengths versus lengths actually implanted is also implemented.

Disclosed is a marking composition comprising a marker and a hydrogel. Disclosed is a process of forming a marking composition comprising mixing a marker and a hydrogel. Disclosed is an article comprising a marker, a hydrogel, and an implement. Disclosed is a kit comprising a marker, a hydrogel, and an implement, wherein the marker and hydrogel are combined. Disclosed is a method for marking a portion of the brain in a mammal comprising: (a) removing a portion of a mammal's skull to expose a portion of the brain matter; and (b) contacting the exposed portion of the brain with a marking composition. Disclosed is a method for recording electrical activity in a brain, comprising: (a) removing a portion of the skull, thereby exposing a portion of a brain; (b) inserting an electrode into the brain; and (c) recording electrical activity via the electrode, wherein the electrode is at least partially coated with a marking composition.

This application relates to the field of medical ultrasound measurement technology, specifically providing a method for in-situ measurement of skull thickness and sound velocity using ultrasound. The method includes: acquiring reflected echo data from N transmitting array elements, wherein the N transmitting array elements sequentially transmit ultrasound waves to the location to be measured on the skull, and array elements centrally symmetrical to the transmitting array elements receive the reflected echoes of the ultrasound waves; arranging the reflected echo data from the N transmitting array elements together to form a wave train diagram of the N transmitting array elements; extracting the sound pressure amplitude values ​​corresponding to the normal incident reflection time from the wave train diagram, and superimposing the extracted sound pressure amplitude values ​​to form a superimposed amplitude spectrum, with the maximum superimposed sound pressure amplitude value corresponding to the wave train diagram being the equivalent matching velocity; and calculating the sound velocity and thickness at the location to be measured on the skull based on the equivalent matching velocities at the maximum superimposed sound pressure amplitude values ​​and the normal incident reflection time. This method can accurately measure the sound velocity and thickness of the skull in situ.

This invention provides an acoustically transparent skull based on the transfer matrix method. The skull includes a matching layer, a coupling layer, and a biomimetic skull. The biomimetic skull matrix has acoustic windows and a stepped groove design for easy and quick assembly, disassembly, and repositioning. The matching layer module is made of epoxy resin-nano-alumina composite material, and its thickness is designed according to a quarter wavelength of the target frequency band. This effectively optimizes acoustic impedance matching and reduces energy loss, becoming a key breakthrough in improving the transmission efficiency of transcranial ultrasound and expanding its application in non-invasive medical fields. This invention focuses on the field of biomechanics and medicine, addressing the problem of low transmission efficiency in transcranial ultrasound technology caused by differences in acoustic impedance of the skull. It can be used to compare the sound transmission effects of single or multiple matching layers at different frequencies. In the future, ultrasound can be more widely used for diagnosis, treatment, neuromodulation, and health / mental status monitoring of astronauts.

The invention relates to a transcranial cell stimulation experiment model, which is characterized in that a support structure is used for supporting a skull model, the upper end of the support structure enters the skull model, a placement platform fixed on the support structure is arranged in the skull model, a cell culture dish is placed on the placement platform, two sides of the skull model are respectively provided with a stimulation coil which is obliquely distributed, and the stimulation coils are arranged on the skull model. The power supply unit is used for rapidly discharging to the two stimulation coils so as to induce generation of transient strong pulse current in the stimulation coils, and a 1T-4T strong magnetic field is formed around the stimulation coils. A transcranial cell stimulation experiment method comprises the following steps: firstly, pretreating SH-SY5Y cells, and then putting the pretreated SH-SY5Y cells into a cell culture dish; specific current waveforms are transmitted to the two stimulation coils, and the SH-SY5Y cells are stimulated through a generated electromagnetic field. The method has the beneficial effects that experimental simulation and experimental verification are realized, the understanding of a non-invasive brain stimulation technology is enriched, and a new scientific basis is provided for the treatment of related neurological and mental diseases.

The invention relates to the technical field of ultrasound, in particular to an ultrasonic incident angle correction method, a program product and a self-adaptive transducer. According to the method, an incident wave is emitted to a target object, a reflected wave reflected by the target object is received, and whether the intensity of the reflected wave reaches a preset condition or not is judged; if not, the incident angle is adjusted until the reflected wave reaches the preset condition, the incident angle of the ultrasonic wave can be automatically adjusted in real time, the incident angle is made to be matched with the normal direction of the skull surface, and therefore the problems of sound energy attenuation and efficiency reduction caused by the too large incident angle are avoided; dependence on traditional high-resolution medical imaging equipment is reduced, and a complex and time-consuming individualized customization process is omitted; the skull penetrating efficiency of ultrasonic energy is improved, the output energy and the focusing effect of the whole transcranial focusing ultrasonic system are optimized, and the reliability and effectiveness of a treatment scheme are improved accordingly.

The invention discloses a floating bone flap and skull connecting device which comprises a fastening screw, a connecting piece and a plurality of traction lines, a first through hole is formed in the middle of the connecting piece, the fastening screw is sleeved with the connecting piece through the first through hole, and the fastening screw is locked in the middle of the upper end face of a floating bone flap. The connecting piece is located between the head of the fastening screw and the upper end face of the floating bone flap, a slipknot is arranged at one end of each traction line, and a second through hole is formed in each slipknot; a plurality of third through holes are formed in the edge of the floating bone flap at intervals, and a plurality of fourth through holes are correspondingly formed in the edge of the skull window; the other end of each traction line penetrates through the corresponding third through hole, the corresponding fourth through hole and the second through hole of the slipknot at one end of the traction line and then is connected to the connecting piece. After the skull flap is connected with the skull, tension and flexibility are good, the skull flap floats upwards sufficiently, and intracranial pressure reduction of a patient can be sufficient and thorough; and after the intracranial edema period, secondary fixation of the floating bone flap is facilitated, and the bone flap is prevented from sinking.

The invention discloses a clinical skull fracture repairing device suitable for neurosurgery department, which comprises a protective shell, a connecting ring is fixedly mounted on the lower surface of the protective shell, a mounting bottom frame is arranged on the outer side of the lower end of the protective shell, a first prefabricated groove matched with the connecting ring is formed in the mounting bottom frame, and a second prefabricated groove matched with the connecting ring is formed in the mounting bottom frame; a fixing block is integrally and fixedly mounted on the outer surface of the mounting bottom frame, and a sponge ring is arranged at the inner wall end of the mounting bottom frame in a sticking manner; the elastic band is arranged on the outer side of the lower end of the mounting bottom frame, and the outer side of the lower end of the elastic band is connected with a matched fixing buckle; and the second prefabricated groove is formed in the lower end of the protective shell, and air holes are formed in the upper end of the protective shell in a penetrating mode. According to the clinical skull breaking repairing device suitable for the neurosurgery department, the protective shell can be conveniently and directly detached from the head of a patient, follow-up medicine changing and other work are facilitated, meanwhile, the massage function is achieved, and the situation that the head of the patient is prone to itching is conveniently relieved.

The application discloses a skull local point cloud registration method based on adaptive geometry-appearance joint cost, relates to the field of point cloud registration, and comprises the following steps: performing three-dimensional reconstruction on preoperative CT slices to obtain a skull CT point cloud model; performing semantic segmentation on RGB-D data of an intraoperative anatomical structure to obtain a target region mask; performing spatial back projection on depth in the target region mask to generate surface point cloud with color attributes; performing guided completion and filtering on missing and weak areas of the surface point cloud with color attributes according to an edge confidence map extracted from color and depth, to obtain a completed point cloud retaining important boundaries; and constructing an adaptive geometry-appearance joint cost to perform rigid registration on the skull CT point cloud model and the completed point cloud, so that accurate alignment of a spatial position of a patient during operation and the skull CT point cloud model is realized without using body surface calibration points.

This invention relates to the field of medical testing equipment, specifically to a pulsatile tinnitus detection device. The device includes a wearable body worn on the user's head, with symmetrically arranged sensing mechanisms on the wearable body for contacting specific areas of the user's skull to collect physiological signals. The wearable body also includes an intervention mechanism for simulating different hemodynamic states; the intervention mechanism includes an actuator and a compression head, the actuator driving the compression head to perform controllable compression and release. A control unit is also included, communicatively connected to the sensing and intervention mechanisms. The control unit controls the actions of the intervention mechanism, receives and analyzes the physiological signals collected by the sensing mechanisms, and correlates changes in physiological signals with the timing of compression and release actions to generate assessment information for determining the cause of pulsatile tinnitus, intraoperative effects, or postoperative recovery. This invention is used to objectively assess vascular recovery status, providing standardized and comparable assessment indicators for diagnosis and treatment.

The application provides a child skull fracture automatic detection method and device based on generated data augmentation. The method comprises the following steps: acquiring a first child brain CT image set, and performing pixel labeling and preprocessing to obtain fracture data, suture data and normal data; obtaining a trained fracture lesion generation model and a suture generation model according to the fracture data, the suture data and the normal data; randomly sampling Gaussian noise for multiple times, inputting the Gaussian noise into the fracture lesion generation model and the suture generation model to obtain generated fracture CT patch data and generated suture CT patch data; training a candidate fracture detection model according to the fracture data, the suture data, the normal data, the generated fracture CT patch data and the generated suture CT patch data, and outputting a fracture detection model; and acquiring a second child brain CT image, and detecting the second child brain CT image according to the fracture detection model. The fracture lesion data and the suture data are augmented, so that the resolution of fractures and sutures can be improved.

The utility model discloses a craniocerebral dissecting table for medical test and teaching, and relates to the technical field of medical teaching, the craniocerebral dissecting table comprises a base and a positioning head frame, the positioning head frame is arranged on the base through a fixing support, the front side of the positioning head frame is provided with an open skull placing position, and the positioning head frame is arranged on the base. An upper positioning rod and a lower positioning rod which are used for fixing the skull are arranged on the upper side and the lower side of the skull placing frame respectively, the upper positioning rod is rotationally connected with the skull, and the lower positioning rod is fixedly connected with the skull and rotationally connected with the positioning head frame. The positioning head frame is provided with a damping piece used for enabling the lower positioning rod to rotate in a damping mode. The skull is fixed through the upper positioning rod and the lower positioning rod, the skull is driven to rotate through rotation of the lower positioning rod, the position of the skull can be kept still through the damping piece under the condition that the lower positioning rod does not have external force, and therefore the skull structure can be observed at different angles.

The application provides a guide plate for minimally invasive surgery, and relates to the technical field of skull minimally invasive surgery, and comprises a personalized customization piece, which is customized based on three-dimensional data of a patient, is suitable for being attached and worn on a target part of the patient, and is provided with a first connecting part; a standardized connecting piece, which is made of a material that is not easy to deform under high-temperature sterilization, is provided with a second connecting part for forming a detachable connection with the first connecting part, and is provided with a third connecting part; and a personalized guide piece, which is made of a material that is not easy to deform under high-temperature sterilization, is provided with a guide channel for guiding a medical implanting instrument to pass through, is provided with a fourth connecting part for forming a detachable connection with the third connecting part, and is located on an implanting path planned before surgery after the fourth connecting part is connected with the third connecting part. The manufacturing cost of the guide plate is reduced, and the good accuracy of the guide plate is ensured.