17 results about "Isovaleraldehyde" patented technology

The application discloses a hydroxylamine hydrochloride detection method in azithromycin dry suspension, and relates to the trace detection field. The method uses isoamyl aldehyde as a derivatizing agent, generates isoamyl aldoxime by performing derivatization treatment on a sample to be measured, and then uses N-nitrosodiisopropylamine as an internal standard substance to quantitatively determine the isoamyl aldoxime by using liquid chromatography-tandem mass spectrometry. The detection method adopts an isoamyl aldehyde derivatizing agent-N-nitrosodiisopropylamine internal standard substance system, can correct detection errors caused by factors such as matrix effect, pretreatment loss and derivatization efficiency fluctuation, and improves the accuracy and sensitivity of the trace hydroxylamine hydrochloride detection result, thereby guaranteeing the safety of the medicine.

The present invention relates to a method for the preparation of 3-methyl-3-butene-1-ol (isoprenol), comprising the steps of preparing isobutylene (also: isobutene, 2-methylpropene) by contacting 3-methylbutan-1-ol (isoamyl alcohol) to a catalyst comprising at least one catalytically active metal and reacting at least one formaldehyde source and the isobutylene obtained in step a-i) to obtain isoprenol. Furthermore, the present invention refers to processes for the preparation of 3-methyl-2-butene-1-ol (prenol), of 3-methyl-3-butenal (isoprenal), of 3-methyl-2-butenal (prenal), and of 3,7-dimethy l-octa-2, 6-dienal (citral) and further downstream products comprising the use of isoprenol of the present invention and the resulting products and product streams.

The application discloses a synthesis method of 5,5-dimethyl 2-isoxazoline. First, isoamyl aldehyde is added with hydrogen chloride to generate chloroisoamyl aldehyde, then under alkaline conditions, the chloroisoamyl aldehyde generated in step one is added with hydroxylamine salt to generate chloroisoamyl aldehyde oxime, finally under alkaline conditions, the chloroisoamyl aldehyde oxime generated in step two is cyclized to generate 5,5-dimethyl 2-isoxazoline, the yield is high, the process is simple and suitable for industrial production; compared with the traditional method, the synthesis method has the characteristics of mild reaction condition, green environmental protection and low cost.

The present invention relates to a photocatalyst and a preparation method therefor. The photocatalyst according to the present invention comprises titanium dioxide with a bronze crystal phase and an anatase crystal phase so as to have high photoactivity, and thus is suitable for removing odors and toxic gases. In addition, the titanium dioxide included in the photocatalyst, according to the present invention, has a novel crystal phase having a charge separation effect superior to those of other crystal phases, and thus has improved photoactivity. Additionally, the photocatalyst of the present invention has high photoactivity, and thus is suitable for removing odors and toxic gases. In addition, the photocatalyst of the present invention has excellent durability against catalytic poisons formed on the surface of a catalyst during removal of VOCs and toxic gases (acetaldehyde, isovaleraldehyde, isovaleric acid and toluene).

The invention discloses a preparation method of composite roasted peanut essence, which belongs to the technical field of essence, and comprises the following steps: preheating peanut oil and caprylic / capric triglyceride; the preparation method comprises the following steps: dissolving ethyl maltol, vanillin, methyl cyclopentenolone, 2, 3, 5-trimethylpyrazine and 2-acetylpyrazine; vanillin propylene glycol acetal, isovaleraldehyde propylene glycol acetal, triethyl citrate, delta-decalactone, delta-dodecalactone and 5-hydroxyethyl-4-methylthiazole are fused to obtain a mixture; dispersing the roasted peanut extract; 2, 3-dimethylpyrazine, 2-methoxyl-5-methylpyrazine and 4-methylthiazole are fused, and then the mixture is subjected to a reaction; the preparation method comprises the following steps: fusing cocaal, dimethyl sulfide, 2-ethyl-3, 5, 6-dimethylpyrazine, 2, 3, 5, 6-tetramethylpyrazine, 2-methylpyrazine, 2-acetylpyridine, 2-methoxy-3. 5. 6-isopropyl pyrazine, 2-methylthio-3-methylpyrazine, isovaleric acid, 1-octylene-3-alcohol, 5-methylfurfural and 3, 4-dimethyl-1, 2-cyclopentanedione; standing is performed; filtering is performed; the fragrance of the roasted peanuts is closer to that of the roasted peanuts which are just taken out of a furnace, and the natural flavor of the roasted peanut essence is increased.

The invention provides a depolymerization method of impurities in a floridin reaction liquid and a preparation method of floridin, and the specific steps are as follows: the floridin reaction liquid containing polyisovaleraldehyde is subjected to a depolymerization reaction under the catalytic action of a loaded MgO / Beta molecular sieve to obtain a floridin depolymerization reaction liquid basically containing no polyisovaleraldehyde, and the floridin depolymerization reaction liquid containing no polyisovaleraldehyde is subjected to a depolymerization reaction under the catalytic action of a loaded MgO / Beta molecular sieve. And separating the catalyst in the depolymerization reaction liquid, and carrying out optional refining to obtain a white flower alcohol product. The method disclosed by the invention has the advantages of mild conditions, no solvent, simple process, high depolymerization rate, no influence on the yield of the white flower alcohol, obvious improvement on the fragrance of the product and the like.

The invention belongs to the technical field of biology, and particularly relates to an adipose tissue-derived stem cell factor composition as well as a preparation method and application thereof. The adipose tissue-derived stem cell factor composition is prepared from the following components in parts by weight: 120 to 150 parts of adipose tissue-derived stem cell culture supernate, 1 to 7 parts of BPC157, 5 to 10 parts of cyanidin-3-O-glucoside and 0.5 to 1 part of isovaleraldehyde. Water content and cytokine content detection experiments prove that the composition disclosed by the invention can effectively maintain the stability and activity of cytokines and is beneficial to long-term storage of cytokine products. Furthermore, anti-aging detection experiment data also fully shows that the composition disclosed by the invention can be used for preparing the medicine for resisting skin aging.

The invention discloses a preparation method of chocolate essence for cigarettes, the chocolate essence for cigarettes and an aerosol generating product, the chocolate essence comprises the following components: an isovaleraldehyde condensation reactant, a vanillin acetal reactant and a cocoa concentrate, the isovaleraldehyde condensation reactant is formed by carrying out a first condensation reaction on isovaleraldehyde and a first alcohol reactant, and the vanillin acetal reactant is formed by carrying out a second condensation reaction on a second alcohol reactant; the vanillin acetal reactant is prepared by carrying out a second condensation reaction on vanillin and a second alcohol reactant, and the cocoa concentrate is prepared by concentrating a cocoa extract. According to the invention, unsaturated carbonyl in aldehyde molecules and a common solvent of essence are subjected to obvious aldol condensation reaction under an acidic condition to form an acetal compound with good stability, the problem of insufficient fragrance of the chocolate extract is solved, and on the basis of the acetal reactant, through technical means such as essence blending and modification, the flavor of the chocolate extract is improved. The chocolate essence which is fragrant, mild, mellow and full is constructed, and the application requirements of export cigarettes on flavor type essence are met.

This invention discloses a method for the oxygen-free dehydrogenation of isopentyl alcohol to isopentylaldehyde catalyzed by a zinc oxide-based catalyst, comprising: catalyzing the oxygen-free dehydrogenation of isopentyl alcohol in an inert atmosphere using a zinc oxide-based catalyst to generate isopentylaldehyde; the zinc oxide-based catalyst includes a support and zinc oxide supported on the support; the support is hydroxyapatite. This invention uses a zinc oxide-based catalyst, ensuring the stability of the active components of the catalyst during the oxygen-free dehydrogenation of isopentyl alcohol to isopentylaldehyde, preventing sintering, reduction, and loss. The method of this invention is simple to operate and economically efficient. The catalyst is green and efficient, suitable for the oxygen-free dehydrogenation of isopentyl alcohol, and conducive to large-scale production, showing good industrial application prospects.

The invention discloses a synthesis method of a thermosensitive dye pink pigment, and particularly relates to a synthesis method of 9-(ethyl (isoamyl) amino)-3 'H-spiro [benzo [A] xanthene-12, 1'-isobenzofuran]-3 '-ketone. Comprising the following steps: reacting N-(3-hydroxyphenyl) acetamide with borane tetrahydrofuran at 50 DEG C to prepare N-ethyl-3-methoxyaniline, and reacting the N-ethyl-3-methoxyaniline with isovaleraldehyde and acetic acid sodium borohydride to prepare N-ethyl-N-isopentyl-3-methoxyaniline; then refluxing with an HBr / acetic acid system at 100 DEG C to prepare 3-(ethyl (isoamyl) amino) phenol; then reacting with phthalic anhydride at the temperature of 100 DEG C to prepare 2-(4-(ethyl (isoamyl) amino)-2-hydroxybenzoyl) benzoic acid; and reacting the obtained product in methanesulfonic acid or concentrated sulfuric acid at room temperature, and performing post-treatment to obtain a target product. The method is low in reaction temperature, free of byproducts, low in raw material cost and easy to industrialize.

The application provides a device and method for producing isopentanal byproduct of oil phase of 2-propyl heptanol production device condensation circulating tower, and relates to the field of chemical industry.The device comprises a first rectifying tower and a second rectifying tower;the inlet of the first rectifying tower is communicated with the oil phase outlet of the overhead chromatograph of the 2-propyl heptanol condensation circulating tower, the bottom outlet of the first rectifying tower is communicated with the inlet of the second rectifying tower, and the bottom outlet of the second rectifying tower is communicated with the inlet of the 2-propyl heptanol condensation reactor.The method comprises the following steps: introducing materials from the oil phase outlet of the overhead chromatograph to the first rectifying tower, separating in the first rectifying tower, and obtaining a crude pentanal mixture at the bottom;the crude pentanal mixture is sent to the second rectifying tower for separation, crude n-pentanal is obtained at the bottom, and isopentanal product is obtained at the top.The device and method provided by the application simultaneously realize the production and separation of isopentanal, effectively reduce energy consumption, the equipment is simple, the production capacity is high, and large-scale industrial production is suitable.

The present invention relates to a process for the preparation of 2-isopentyl-2- isopropyl-1,3-dimethoxypropane, said process comprising the steps of: i) contacting iso-valeraldehyde with an aqueous solution of a hydroxide base selected from the group consisting of sodium hydroxide (NaOH), potassium hydroxide (KOH) or a combination thereof, said solution having an amount of said hydroxide base of at least 20% w / v, and (m) ethanol; form (2Z)-2-isopropyl-5-methyl-2-hexenal; step ii) contacting (2Z)-2-iso-propyl-5-methyl-2-hexenal with a reducing system to form 2-isopropyl-5-methylhexanal; step iii) contacting 2-isopropyl-5-methylhexanal with formaldehyde and an inorganic base to form 2-isopentyl-2-isopropylpropane-1,3-diol; and step iv) contacting 2-isopentyl-2-isopropylpropane-1,3-diol with a methylation agent and a base to form 2-isopentyl-2-isopropyl-1,3-dimethoxypropane.

The application discloses coffee essence, atomized liquid and electronic atomization device, and belongs to the field of electronic atomizers. The coffee essence comprises 2-acetylpyrrole, vanillin, methylcyclopentenolone, maltol, furfuryl acetate, guaiacol, isopentyl alcohol propylene glycol solution, furfuryl mercaptan, 2-ethyl-3,5-dimethylpyrazine, isovaleric acid propylene glycol solution, 2,3,5-trimethylpyrazine, isobutyraldehyde, 2-methyl-3-(methylthio)pyrazine, isoamyl aldehyde, trigonellin, 4-hydroxy-2,5-dimethyl-3(2H)-furanone, 5-methylfurfural, dimethyl sulfide, 2-acetylfuran, 5-hydroxyethyl-4-methylthiazole, 2-acetylpyrazine, 4-ethylguaiacol, acetic acid, propionic acid, acetaldehyde propylene glycol solution, 4-methyl-5-(2-acetyloxyethyl)-thiazole and propylene glycol. The coffee essence has good stability, good compatibility and can accurately restore the real coffee roasting aroma.

The invention relates to the field of lily pyran production, and discloses a synthesis process of lily pyran, which comprises isopentenol, isovaleraldehyde and an acid catalyst solution, the proportion of the isopentenol is 0.90-1.05, the proportion of the isovaleraldehyde is 1.0, and the proportion of the acid catalyst solution is 0.2-0.7; the acid catalyst solution comprises an organic acid or inorganic acid solution, and isopentenol is used as one of core raw materials of the reaction, provides an olefin structural unit, and forms a pyran ring skeleton of convallaria majalis pyran through Prins cyclization reaction with isovaleraldehyde. According to the invention, the microreactor and the micromixer cooperate to realize rapid and uniform mixing and efficient mass transfer of the raw materials, the reaction retention time is only 8-21 minutes, the whole process takes 2-4 hours, and the time is greatly shortened compared with the traditional intermittent reaction; the yield of isovaleraldehyde reaches 80.6%-83.4%, the conversion rate of isopentenol reaches 96.8%-98.1%, the purity of a crude product is 85%-90%, the purity of a refined finished product is larger than or equal to 99%, and the problems that a traditional process is low in efficiency and insufficient in purity are solved.

This invention provides a coffee flavoring and its preparation method, comprising 0.1 parts of furanone, 2-acetylpyrazine, vanillin, ethanol, 3-methylthiopropional, 2-methoxy-4-vinylphenol, 2-ethyl-3-methylpyrazine, 2-ethyl-3,5-dimethylpyrazine, furfuryl mercaptan, β-damascone, p-cresol, hexanoic acid, 2-methylbutyric acid, 2,3-pentanedione, methyl furfuryl disulfide, 3-mercapto-3-methylbutyl formate, terpineol, 1-octen-3-ol, isobutyraldehyde, furfural, 5-methylfurfural, isovaleraldehyde, linalool, 2-methoxy-3-isobutylpyrazine, phenylacetaldehyde, eugenol, 2,3,5-trimethylpyridinium, guaiacol, 4-ethylguaiacol, an amino acid composition, glycerol, water, and coffee extract. The coffee flavoring of this invention has a strong three-dimensional aroma, rich layers, and high overall aroma realism and harmony.

The purpose of the present invention is to provide: a food composition which can achieve a good flavor balance as a whole; a method for producing the food composition; a seasoning; a method for producing the seasoning; a flavor improving agent for seasonings; and a method for enhancing a flavor. This food composition is characterized by satisfying all of the following requirements (1) to (3). (1) The water content in terms of wet mass is 20% by mass or more. (2) Isovaleraldehyde is contained in an amount of 10 ppb by mass or more. (3) At least one requirement selected from the group consisting of the following requirements (A) to (E) is satisfied. (A) The content of benzeneacetaldehyde is 1 ppb by mass or more. (B) The content of 2-methylfuran is 1 ppb by mass or more. (C) The content of 2,3-pentanedione is 4 ppb by mass or more. (D) The content of 1-penten-3-ol is 10 ppb by mass or more. (E) The content of furfural and a furfural-based compound is 30 ppb by mass or more.

This invention relates to a method for preparing isopentenal and isopentral, the method comprising the steps of: (a) contacting a gaseous reactant stream containing isopentenol, isopentol, and optionally isopentral with a silver-containing heterogeneous catalyst in the presence of molecular oxygen to obtain a product stream containing isopentenal, isopentenal, and isopentral; (b) separating isopentenal, isopentenal, and isopentral from the product stream; (c) isomerizing isopentenal contained in the mixture obtained in step (b) to isopentenal; and (d) separating isopentenal and isopentral from the mixture obtained in step (c). Isopentral can be produced simultaneously with isopentenal and isopentenal in a high yield and with high selectivity in an energy-efficient manner in a single production facility.