The invention discloses a Chinese herbal medicine source pesticide, and belongs to the technical field of agricultural production. The Chinese herbal medicine source pesticide is prepared from ageratum, cortex phellodendri, flos caryophylli, fructus mume, radix sophorae subprostratae, radix sophorae flavescentis, radix stemonae, rhizoma coptidis, cortex dictamni, sweet wormwood herb, rhizoma polygoni cuspidati, herba artemisiae scopariae, radix pulsatillae, rhizoma curcumae longae, cortex moutan radicis, radix lithospermi, cortex fraxini, borneol, pine needles and caulis fibraureae. Spraying of the pesticide is beneficial to prevention and treatment of fungal and bacterial diseases such as powdery mildew, downy mildew, gray mold and rust disease on vegetables and fruits and insect pests such as thrips, red spiders, aphids and liriomyza sativae in the vegetables and fruits. Normal growth of the vegetables and fruits is guaranteed, use of chemical pesticides is gradually reduced, pollution of pesticide residues to the vegetables and fruits is reduced, harvest and high yield of the vegetables and fruits are promoted, and the effects of low cost and low toxicity are achieved.