96 results about "Cyromazine" patented technology

The invention discloses molecularly imprinted polymers (MIPs) for detecting melamine and a preparation method thereof. The MIPs are prepared by the steps as follows: cyromazine is used as a virtual moulding board and is polymerized with a functional monomer, a cross linker agent, a pore-foaming agent and an initiator at the temperature from 50 to 80 DEG C to obtain a bulk polymer; and after being processed by the operations of pulverization, screen separation, moulding board removal by acetic acid methanol and methanol, the bulk polymer is processed by vacuum drying to prepare the MIPs which have high cross reaction and outstanding selectivity to melamine. The invention selects the cyromazine as the virtual moulding board to prepare the MIPs, and avoids the problem that the melamine is hard to dissolve in a polymerization system and the problem that when the MIPs prepared by using the melamine as the moulding board is used for solid phase extraction of fill materials, moulding board leakage can lead to an inaccurate result; the invention selects the mixed system of methanol and water as the pore-foaming agent, and the prepared MIPs have high compatibility with the melamine in an aqueous solution; and used as a sample pre-processing material for analyzing the melamine, the prepared MIPs have broad application prospect.

The invention discloses a method for measuring residues of seven pesticides in wool fat by liquid chromatography-tandem mass spectrometry, and belongs to a chemical detection method. A liquid-liquid extraction frozen degreasing method is used as pretreatment; and the pesticide residues in the wool fat are detected and analyzed by the liquid chromatography-tandem mass spectrometry. According to the detection method disclosed by the invention, a wool fat sample extract solution is not required to be concentrated and can be measured in a machine only after being purified, so that the detection is quick and accurate, and the sensitivity is higher; the using amount of solvents is small, the extraction efficiency is high, grease can be completely removed, and the target retaining capacity is high; the residues of seven pesticides, such as cyromazine, dicyclanil, diflubenzuron, triflumuron, rotenone, abamectin and ivermectin can be detected at the same time; the target response signal is strong; the average recycling rates are 66.77-105.48 percent respectively; the relative standard deflection RSD is 1.38-8.09 percent; and the method has certain actual application and innovative signification.

The invention discloses a rapid detection test strip for combined detection of cyromazine and melamine residues and a preparation method thereof. The nitrocellulose membrane (4) is coated with a rabbit anti-mouse IgG quality control line (5) and MA-BSA, CA - two detection lines for BSA (6); the anti-MA drug monoclonal antibody-colloidal gold marker and the anti-CA drug monoclonal antibody-colloidal gold marker coated on the binding pad (8). The present invention screens out anti-MA drug monoclonal antibodies and anti-CA drug monoclonal antibodies by using immunological technology, and through the preparation of colloidal gold and the exploration and research of colloidal gold labeling conditions, in the application of anti-MA drug monoclonal antibodies, anti-CA drug monoclonal antibodies Research on Cloning Antibody and Colloidal Gold Technology Establish colloidal gold test strips for dual detection of anti-MA and CA drugs, and measure their performance. The test strip has a wide range of detection samples, low false positives, sensitive, accurate and reliable detection, and is suitable for dual detection of CA and MA drug residues in animal edible tissues such as muscle, liver and kidney and milk.

The present invention discloses a method for simultaneous detection of a plurality of content of non-protein nitrogen-containing compounds in milk by liquid chromatography-tandem mass spectrometry, the method is as follows: adding a protein precipitant into a to-be-tested sample, whirling, centrifuging, adding a degreasing agent into supernatant, whirling, centrifuging, removing a degreasing agent layer, concentrating a lower clearing liquid, dissolving with ammonia acetonitrile, whirling, performing column chromatography with a HLB solid phase extraction column, collecting an eluant, concentrating, dissolving with a liquid mixture of a 0.15% formic acid aqueous solution (containing 5mM of ammonium acetate) and acetonitrile in the volume ratio of 1: 9, and filtering to obtain a to-be-tested solution; preparing a standard mixing working solution series; respectively injecting the standard mixing working solution series and the to-be-tested solution under liquid chromatography-tandem mass spectrometry conditions, making a standard curve, and calculating the content of the non-protein nitrogen-containing compounds in the to-be-tested solution according to the standard curve. The method can be used to simultaneously detect the content of at least two of dicyclanil, dicyandiamide, biuret, cyromazine and melamine, and is high in accuracy and strong in sensitivity.

A pesticide composition containing cyromazine with synergism comprises two active components of compound of (4'R)-4'-deoxy-4'-(methylamino)-avermectin B1 benzoate ( emamectin benzoate-chlorfenapyr for short), and cyromazine (chemical name is N-cyclopropyl-1,3,5-triazine-2,4,6-triamine) with the mass percent of 0.1:20-1:80. The inventive composition has special activity to harmful arthropods with remarkable synergism to induce them to be in aberration by small dosage and excellent contact toxicity, gastric toxicity and systematic effect.

The invention discloses an insecticidal composition containing spinosad and cyromazine as well as a preparation method and application thereof. The insecticidal composition is characterized by containing the spinosad, the cyromazine and other assistants, wherein the weight ratio of the spinosad to the cyromazine is 1:140-4:1. The insecticidal composition can be used for controlling various injurious insets and has the advantages of safety, environmental protection, low cost and good effect. An indoor toxicity test and a field test prove that the composition has an obvious synergistic effect. Because no report on the blending of the spinosad and the cyromazine exists at home and abroad, the invention provides the insecticidal composition.

The invention discloses a method for preparing cyromazine. The method includes steps of 1), dissolving cyanuric chloride in organic solvents under stirring conditions at the temperature of 0-5 DEG C,then dropwise adding industrial ammonia water into the organic solvents to obtain mixtures, heating the mixtures until the temperatures of the mixtures reach 40-45 DEG C, carrying out thermal reactionfor 5-6.5 h to obtain reaction liquid, separating solvents from the reaction liquid, adding purified water into residual liquid, stirring the purified water and the residual liquid for 1-1.5 h to obtain mixed liquid, cooling the mixed liquid until the temperature of the mixed liquid reaches the room temperature and carrying out suction filtration, washing and drying to obtain an intermediate which is 2-chlorine-4.6-diamino-1.3.5-triazine; 2), adding the intermediate prepared at the step 1) into purified water at the room temperature, adding cyclopropylamine into the purified water to obtain first mixtures, heating the first mixtures until the temperatures of the first mixtures reach 90-95 DEG C, dropwise adding acid binding agents into the first mixtures to obtain second mixtures, regulating the pH (potential of hydrogen) of the second mixtures until the pH of the second mixtures reaches 7.5-8.5, then carrying out reaction at the temperature of 98-100 DEG C for 3.5-4.5 h, carrying outdecolorization and filter to obtain reaction solution, cooling the reaction solution until the temperature of the reaction solution reaches 40-50 DEG C, crystallizing the reaction solution for 1-2 h,continuing to cool crystals until the temperatures of the crystals range from -5 DEG C to 0 DEG C, carrying out suction filtration and washing and then carrying out drying to obtain the cyromazine. The method has the advantages that the method includes simple processes and is high in safety and low in cost, and industrial production can be facilitated; the cyromazine which is a product is high inpurity, low in impurity content and good in stability.

The invention discloses a method for detecting cyromazine. The method comprises the following steps: preparing a polyT10@nanogold solution; adding cyromazine solutions with different concentrations, reacting, adding sodium chloride solution, reacting to obtain a standard solution, measuring the absorbance value of the standard solution at 520 nm, and drawing a standard curve for measuring the cyromazine content with the absorbance value as a vertical coordinate and with a cyromazine concentration logarithm as a horizontal coordinate; measuring the absorbance value of a solution to be measured at 520 nm, and obtaining the content of cyromazine in a sample to be measured according to the standard curve. The invention provides a quick, simple and sensitive method for measuring residual cyromazine in fruit and vegetable products, no complicated instrument, for example, chromatographic instrument-mass spectrometer, is needed, the operation is simple, and color change can be observed by naked eyes and can also be accurately quantified by measuring the absorbance. The detection time of the method is short, no toxic extraction reagent is needed, the costs of the used nanogold and aptamer are low, and the method can be used for quickly and early screening and inspecting a large number of samples on site.

The invention provides pig farm site bedding and relates to the technical field of livestock breeding. The pig farm site bedding is prepared from 60-80 parts of minced straw, 20-30 parts of quick lime, 10-20 parts of grain husks, 20-30 parts of potassium permanganate powder, 6-10 parts of costustoot leaves, 30-40 parts of montmorillonite powder, 10-20 parts of honeysuckle extracts, 3-5 parts of cyromazine, 4-6 parts of chlorine dioxide, 7-9 parts of palygorskite powder, 15-25 parts of soda ash, 6-8 parts of mildew-proof powder and 30-40 parts of water. The pig farm site bedding has the advantages that adopted raw materials are rich and cheap, the preparing technology is simple and convenient to use, the raw materials are free of toxins and harm, and the bedding can be normally used on a pig farm; meanwhile, the materials of the bedding have insect-expelling and antibacterial effects, warmth is guaranteed, the bedding can expel insects and prevent diseases, effects are obvious, and use and popularization are convenient.

The invention discloses a method for synthesizing lenvatinib. The method comprises the following steps: with 7-methoxy-4-oxo-1,4-dihydro-quinoline-6-formamide as an initial raw material, carrying outan oxo-arylation reaction on the initial raw material and bis(3-chloro-4-amino)phenyl iodine trifluoro-methanesulfonate, carrying out an amidation reaction between 4-(4-amino-3-chloro-phenoxy)-7-methoxy-6-formamide, a product of oxo-arylation reaction, and phenyl chloroformate, and carrying out a urea reaction on a product of amidation reaction and cyromazine, thereby obtaining lenvatinib. The synthetic method has few process route steps and is simple in operation, 7-methoxy-4-oxo-1,4-dihydro-quinoline-6-formamide innovatively replaces 4-chloro-7-methoxyquinoline-6-formamide to serve as the initial raw material, and the method is environmental-friendly and is applicable to industrialized production.

The invention relates to the technical field of veterinary drugs and discloses a fly killing agent containing macleaya cordata and cyromazine. Macleaya cordata and cyromazine are used as active components of the fly killing agent; according to percentage by weight, the weight percentage range of macleaya cordata is 1-5%, and the weight percentage range of cyromazine is 1-10%; in macleaya cordata, the weight percentage of sanguinarine is not less than 1.50%; the total weight percentage of sanguinarine and chelerythrine is not less than 2.25%. Macleaya cordata and cyromazine are matched in use; the cyromazine is used while a certain amount of chelerythrine is added, so that the effects of killing and controlling flies can be improved; the consumption of cyromazine is reduced; the influence on animal organism and environment is reduced; the effects of killing and controlling flies of the fly killing agent are greatly improved; the consumption of cyromazine is effectively reduced; drug pollution and residue can be reduced; the fly killing agent also has the advantages of accelerating parturition, reducing feed conversion ratio, improving animal parturition performance and reducing feeding cost, and has a wide application prospect in the animal farming industry.

The invention discloses feed for feeding lactating sows. The feed comprises the following components in parts by mass: 310 parts of corn meal, 110 parts of soybean meal, 20 parts of imported fishmeal, 10 parts of soybean oil, 30 parts of wheat bran, 75.6 parts of dicalcium phosphate, 36 parts of salt, 75.6 parts of stone powder, 1.2 parts of phytase, 0.12 part of cyromazine, 15 parts of a mildew suppressor, 1.2 parts of rovimix, 0.12 part of biotin and 20.16 parts of medical stone. According to the feeds, the aim of improving the health of the sows and piglets is fulfilled.

The invention relates to a biopesticide and bio-fertilizer combined shade mixture. The shade mixture is composed of 121.96-185.51kg of a liquid and 50-200kg of the photosynthetic bio-fertilizer, wherein the liquid includes, by weight, 3-5.3kg of 95% of efficient cypermethrin, 0.01-0.21kg of 98% of cyromazine, 0.95-1kg of methanol, 38-59kg of a surfactant and 80-120kg of water, wherein the photosynthetic bio-fertilizer is produced by the Shanxi Yongfeng bio-engineering technology limited company. According to the shade mixture, comprehensive application effects of pesticides and fertilizers can be fully improved, the mixture has absolute inhibition effects on insects such as fruit red spiders, aphids, fruit borers, grape caterpillars which are harmful to crops and can increase the sweetness of crops, fruits and vegetables taste good and have good colors and flavors, and the yield can be improved.

The invention discloses a preparation method of cyromazine. Melamine is used as an initial raw material; the preparation method comprises the following steps: carrying out an acidic hydrolysis reaction to obtain 4, 6-diamino-2-hydroxy-1, 3, 5-triazine, carrying out a chlorination reaction on 4, 6-diamino-2-hydroxy-1, 3, 5-triazine to obtain a toluene solution of 4, 6-diamino-2-chloro-1, 3, 5-triazine, and carrying out an amination reaction on 4, 6-diamino-2-chloro-1, 3, 5-triazine and cyclopropylamine so as to generate cyromazine. According to the method, toxic 2-cyclopropylamino-4, 6-dichloro-S-triazine is prevented from being generated, ammoniation pressurizing equipment is prevented from being used, reaction conditions are milder, cheaper materials are used, and the prepared cyclopropylamine is high in yield and good in quality.

Fly-killing bait. The fly-killing bait is powdery and specifically contains the following ingredients (by weight): 1.5-2.5% of Azamethiphos, 0.7-1.2% of imidacloprid, 0.3-1% of pyriproxyfen, 0.5-1.5% of cyromazine, 0.5-1.5% of acetamiprid, 12-20% of fish meal, 3-8% of an adhesive, 65-80% of a sweetener and 1-5% of a coloring agent. According to the fly-killing bait, multiple fly-killing ingredients are used. The bait has a good disinfestation effect and has effectiveness of killing insects including mosquitoes and flies, cockroaches, phalaenae, etc. As disinfestations components are complex, drug resistance of insects will not be easily generated. In addition, the bait has no or little toxicity and harm to pets such as cats and dogs and human and will not cause serious poisoning conditions, and is applicable to places such as hotels, restaurants and the like where people and pets come and go.

The invention discloses a pesticidal composition. The composition is characterized by being prepared from the following components in percentage by weight: 5 to 40 percent of veratrine, 5 to 40 percent of cyromazine and 20 to 90 percent of aid. The composition has the advantages of realizing high efficiency, reducing residues and reducing pesticide consumption.

The invention discloses an insecticidal composition containing clothianidin and cyromazine and application of the composition. The effective active ingredients comprise the first active ingredient clothianidin and the second active ingredient cyromazine, the weight ratio of the first active ingredient to the second active ingredient ranges from 1:50 to 50:1, and the sum of the content of the first active ingredient and the content of the second active ingredient accounts for 1%-80% of the total weight of the composition. The insecticidal composition can be prepared into missible oil, a suspending agent, wettable powder, water dispersible granules, an emulsion in water, microemulsion, a microcapsule preparation, granules and a water-based preparation which are permissible in agriculture. The insecticidal composition is reasonable in component and good in effect on liriomyza and bactrocera dorsalis, and the insecticidal effect of the insecticidal composition is not simple superposition of activity of the ingredients. Compared with an existing single preparation, not only is the significant insecticidal effect achieved, but also a significant synergistic effect is achieved, the dosage is reduced, and the crop safety is good.

The invention provides a diflubenzuron urea granule and a preparation method thereof. The invention is to solve the problems that cyromazine is always used to control and kill fly maggots; no pesticide with same effect can be alternated; pesticide resistance is easily generated; and a conventional diflubenzuron suspension is not applicable to killing the fly maggots in manure of livestock and poultry. The diflubenzuron urea granule provided by the invention uses urea as a carrier and a core, and has the outer layer adhered with a pesticide namely diflubenzuron. The diflubenzuron urea granule is directly subjected to dry spreading into the manure of the livestock and the poultry to control and kill the fly maggots, can slowly sink into the manure and diffuse due to heaviness of the granules, and has better effect to control the fly maggots located at the deep position of the manure; meanwhile, through dry spreading for use, no stress is generated to the livestock and the poultry; no irritation is generated to respiratory tracts of the livestock and the poultry; the content of urea in the manure can be increased; and the fertilizer efficiency of the manure is improved.

The invention relates to a cyromazine detection method based on aptamer modified nanogold, and the method comprises the following steps: 1) adding a to-be-detected solution into a nanogold detection solution, and judging whether the detection solution changes color or not; 2) adding the to-be-detected solution into an aptamer modified nanogold detection solution, and judging whether the detectionsolution changes color or not; 3) adding the to-be-detected solution into a CTAB-containing aptamer modified nanogold detection solution, and judging whether the detection solution changes color or not; 4) carrying out absorbance test on the mixed solution of the to-be-detected solution and the CTAB-containing aptamer modified nanogold detection solution, and obtaining the content of cyromazine inthe to-be-detected solution according to the absorbance. Compared with the prior art, the method is simple and convenient to operate, can qualitatively judge melamine and cyromazine without a large instrument, can quantitatively detect the concentration of cyromazine within a certain range, and has the advantages of high detection speed, accurate detection result, good selectivity, low cost and the like.

The invention, which belongs to the technical field of pesticide detection, discloses a rapid detection method of cyromazine in vegetables. The detection method comprises the following steps: crushinga vegetable sample and fully and uniformly mixing the sample; accurately weighing the vegetable sample and putting the vegetable sample into a centrifugal tube; adding 2% of acetic acid acetonitrile;carrying out homogenizing by using a homogenizer and adding anhydrous Na2SO4 and NaCL during the process of homogenizing; carrying out centrifuging; taking 1mL of supernatant for purification after centrifuging; and carrying out qualitative and quantitative analysis on the treated sample in a high performance liquid chromatography-mass spectrometer to obtain the content of cyromazine in the vegetables. The method has the beneficial effects that the chromatographic peak response of cyromazine in the detection method is good; the peak can appear within 2.37 minutes and the instrument response is high, so that the sample injection time is effectively saved and the detection efficiency of cyromazine is improved; the detection accuracy of cyromazine is obviously improved in the detection method; the adding standard recovery rate of a sample is between 90.01% and 104.81%; and the relative standard deviation is between 0.50% and 3.49%.

The invention relates to a highly-efficient pesticide composition for killing agricultural insects. The efficient pesticide composition is composed of following components in parts by weight: 10-40 parts of cyromazine, 20-60 parts of sufluoxime, 25-45 parts of dinotefuran and 20-60 parts of fipronil. The pesticide composition provided by the invention has the advantages of high efficiency, small use amount, delaying of insect resistance to insecticides and the like; the environmental pollution and the pesticide residues can be effectively reduced; and the highly-efficient pesticide composition has remarkable killing effects on vegetable leafminers, liriomyza huidobrensis, melanagromyza sojae, liriomyza chinensis, and lepidopteron including plutella xylostella, asparagus caterpillars, cotton bollworms, chilo suppressalis, mealybug and the like, and is slight in environment harm.

The invention discloses an insecticidal composition and application thereof and relates to the technical field of pesticide compounding. The insecticidal composition disclosed by the invention contains an effective ingredient A and an effective ingredient B. The effective ingredient A is chlorfluazuron, and the effective ingredient B is one or both of pyriproxyfen and cyromazine. The weight ratio of the effective ingredient A to the effective ingredient B is (1: 60) to (70: 1). The compounded agent is reasonable in proportioning ratio, has a remarkable synergistic effect and particularly has an excellent effect on Diptera pests such as Bradysia odoriphaga, Liriomyza sativae and nymphs thereof, and the like, the amount of application of each single agent can be effectively reduced, and the aims of retarding drug resistance and reducing cost are achieved, so that the compounded agent has an obvious application and popularization value.

The invention provides an insecticidal composition containing novaluron. The insecticidal composition is characterized by being prepared from an active component A and an active component B, wherein the A is the novaluron and the B is one or a combination of more than one of efficient cyfluthrin, bacillus thuringiensis, benfuracarb, lufenuron, cyromazine, chromafenozide, methoxyfenozide, azadirachtin, fosthiazate, pyrazine fipronil, pyridine fipronil, kappa-bifenthrin, kappa-tefluthrin, lepimectin, cyenopyrafen and cyflumetofen; the insecticidal composition further comprises auxiliary agents capable of being used for processing pesticide preparations; the components are prepared into a convectional pesticide preparation which is applied to prevention and control of plant insects.

The invention relates to a pesticide preparation for preventing and treating liriomyza sativae blanchard and bemisia tabaci, and belongs to the technical field of pesticide preparation. A pesticide preparation containing spirotetramat for preventing and treating liriomyza sativae blanchard and bemisia tabaci comprises the following effective components in percentage by weight: 5.0%-30.0% of spirotetramat, 5.0-30.0% of cyromazine, and the balance of adjuvant, wherein the pesticide preparation is an emulsion in water or a suspending agent. The emulsion in water or the suspending agent is prepared from a primary agent and the adjuvant, so that the pesticide preparation is capable of efficiently and thoroughly killing injurious insects, and is less in environmental pollution, low in production cost, and suitable for chemical prevention and treatment of liriomyza sativae blanchard and bemisia tabaci.