32 results about "Cyantraniliprole" patented technology

The invention relates to the technical field of pesticides, in particular to a pesticide composition, application thereof and a pesticide preparation. The pesticide composition comprises a first effective component and a second effective component, the first effective component is 1, 8-cineole, and the second effective component comprises at least one of flonicamid, cyantraniliprole, nitenpyram, flubendiamide, spirotetramat, pyriproxyfen, pymetrozine, dinotefuran and sulfoxaflor. The mass ratio of the first effective component to the second effective component is (50: 1)-(1: 100). Through the synergistic interaction of the first effective component and the second effective component, the prevention and treatment effect is remarkably improved, the prevention and treatment spectrum is expanded, and the field dosage can be greatly reduced; specifically, leaf back bemisia tabaci and trialeurodes vaporariorum can be well controlled, the control effect on bemisia tabaci, trialeurodes vaporariorum, thrips and the like is improved, and the application prospect is good.

The present invention relates to the preparation of cyantraniliprole, comprising the preparation of 8-methyl-2,4-dioxo-1,4-dihydro-2H-benzo[d][1,3]oxazine-6-carbonitrile key intermediate via 2-amino-5-((hydroxyimino)methyl)-3-methylbenzoic acid. Wherein hydroxylamine attacks a benzylic formyl group, to obtain the 2-amino-5-((hydroxyimino)methyl)-3-methylbenzoic acid, that undergoes simultaneously or by consecutive steps dehydrogenation and cyclization to obtain the benzo[d][1,3]oxazine group and the cyano group of the desired product. In addition, an improved method for the synthesis of the benzylic formyl group is also displayed.

The present invention relates to solid water dispersible compositions comprising particulate acetamiprid and paniculate cyantraniliprole characterized by spontaneous and fast disintegration, producing physically stable suspensions of particulate cyantraniliprole in aqueous solutions of acetamiprid, with low agglomeration formation or particle size growth and minimal persistent foam. The present invention also relates to methods of use and process of preparing the solid composition comprising acetamiprid and cyantraniliprole.

The present invention relates to the process of preparation of cyano-benzene derivatives including cyantraniliprole, comprising the preparation of cyano-group via cyanation reagent, wherein the cyanation reagent reacts with benzene derivatives, to form the cyano-benzene derivatives. The present invention provides one-step, high yield, high efficiency, and low-cost cyanation synthesis of cyano substituted substances including common pesticides such as cyantraniliprole.

The application provides an intermediate for synthesizing chlorantraniliprole and cyantraniliprole and a preparation method of the intermediate, and the structural formula of the intermediate is 2-amino-3-methylbenzoic acid. The intermediate is obtained by a -D-A reaction, aromatization and a Hoffmann elimination reaction from a cheap bio-based platform compound 2-methylfuran as a starting material. The whole process does not need a dangerous nitration process and a hydrogenation process, the process has mild reaction conditions, good operability, less wastewater and a high yield of the obtained intermediate, and is very suitable for industrialized preparation of an intermediate required by the high-efficiency insecticides chlorantraniliprole and cyantraniliprole.

The invention relates to a method for simultaneously preparing cyantraniliprole metabolites IN-JCZ38 and IN-J9Z38, and belongs to the technical field of pesticide metabolites. The method comprises the following steps: (1) taking cyantraniliprole as a raw material, and generating a metabolite IN-JCZ38 and a byproduct under the action of H2O2 and alkali; (2) generating a metabolite IN-J9Z38 from the by-product under the action of a dehydrating agent and a catalyst; the alkali is one of sodium hydroxide, sodium carbonate or sodium bicarbonate; the catalyst is one of N, N-dimethyl formamide, pyridine or 3-methylpyridine. The preparation method disclosed by the invention is high in raw material utilization rate and simple in synthesis method, realizes continuous reaction and byproduct reutilization, can be used for simultaneously preparing two metabolites, is beneficial to large-scale preparation of cyantraniliprole metabolites, and meets the demand of cyantraniliprole metabolite samples in pesticide registration toxicology detection.

The invention relates to a chlorantraniliprole hapten, a complete antigen and application of the chlorantraniliprole hapten and the complete antigen. When the chlorantraniliprole artificial antigen and the monoclonal antibody are used for ELISA detection, the specificity is high, the IC50 value is 0.058 [mu] g / L, the detection limit of chlorantraniliprole in a standard solution reaches 0.6 [mu] g / L, and the detection limit of a sample to be detected reaches 2 g / kg; the cross reaction rates with cyantraniliprole, tetrachlorantraniliprole and cyclaniliprole are respectively 20%, 12% and 12%, and the material specificity is greatly improved. By utilizing the chlorantraniliprole hapten, the complete antigen and the antibody, the purpose of rapidly and accurately detecting chlorantraniliprole in a sample can be achieved.

The application belongs to the technical field of pesticide insecticide, and discloses a pesticide composition containing brofenvalerate, which comprises active ingredient A, active ingredient B and active ingredient C; the active ingredient A is brofenvalerate; the active ingredient B is high-efficiency lambda-cyhalothrin; and the active ingredient C is any one of thiamethoxam or thiamethoxam. The pesticide composition can effectively prevent and control various underground pests and seedling stage pests, especially the underground pests and seedling stage pests of peanuts and corns, and can enhance the stress resistance of plants, reduce the amount of pesticide, prolong the effective period, and has no pesticide damage to crops.

This invention relates to a method of controlling, limiting or preventing an infestation of a plant by Oomycetes, which comprises applying to propagation material of said plant, a pesticidal combination comprising a phosphorus-based compound as active ingredient A, and an active ingredient B selected from acibenzolar-S-methyl, fludioxonil, fluxapyroxad, inpyrfluxam, mefentrifluconazole, prothioconazole, sedaxane, triticonazole, oxathiapiprolin, fluoxapiprolin, azoxystrobin, difenoconazole, fluopyram, ipconazole, metyltetraprole, silthiofam, dimethomorph, thiophanate-methyl, natamycin, benzovindiflupyr, pydiflumetofen, picarbutrazox, isocycloseram, cyclobutrifluram, broflanilide, thiamethoxam, imidacloprid, clothianidin, cyantraniliprole, chlorantraniliprole, tetraniliprole, fipronil, and any mixture thereof.

The invention belongs to the field of pesticides, and provides a cyantraniliprole synergistic composition and an application of the cyantraniliprole synergistic composition, and the cyantraniliprole synergistic composition comprises cyantraniliprole and an enzymolysis yellow tube vegetable protein. According to the application, the harmful seaweed yellow tube vegetable extracted protein is used for synergism of cyantraniliprole, so that the application amount and the application frequency of cyantraniliprole can be effectively reduced, the cost is saved, and the green and environment-friendly requirements are met.

The present invention relates to the preparation of cyano-anthranilic acid derivatives from 2-amino-5-formyl-3-methylbenzoic acid derivatives, including 2-amino-5-cyano-3- methylbenzoic acid, in the presence of N-methylpyrrolidone (NMP), N,N- dimethylformamide (DMF), N,N-dimethylacetamide (DMA), dimethylsulfoxide (DMSO), and the mixtures thereof, used as a dehydration agent. The present invention discloses an efficient, high yield process to obtain cyano-anthranilic acid intermediate further leading to the manufacturing of diamides, in particular, cyantraniliprole.

The invention discloses clothianidin and cyantraniliprole compound insecticidal granules and a preparation process thereof.The preparation process comprises the steps that lignin modification is conducted on diatomite powder to obtain pretreated diatomite, and garlic oil is used for conducting modification treatment on the pretreated diatomite to obtain modified diatomite; dissolving clothianidin and cyantraniliprole in methanol to obtain a pesticide solution, adding the modified diatomite into the pesticide solution, carrying out dipping treatment and centrifugation to obtain a precipitate so as to obtain pesticide-loaded modified diatomite, and granulating the pesticide-loaded modified diatomite to obtain pesticide-loaded modified diatomite particles; and finally, coating the pesticide-loaded modified diatomite particles by using a coating liquid under the condition of a pulsed magnetic field, thereby obtaining the pesticide-loaded modified diatomite particles. According to the invention, the preparation process of the clothianidin and cyantraniliprole compound granules is improved, the insecticidal effect is ensured, the toxicity is reduced, and the stability of the granules is improved.

The invention provides an insecticidal composition as well as a preparation method and application thereof, and the insecticidal composition comprises the following components in percentage by mass: 2-7% of spinetoram, 2-7% of cyantraniliprole, 0.2-0.8% of a thickening agent, 3-7% of a wetting dispersant, 0.02-0.06% of a defoaming agent, 0.1-0.5% of a preservative and 0.5-3% of an anti-freezing agent. By using the magnesium aluminum silicate compounded thickening agent, the insecticidal composition disclosed by the invention effectively improves the control effect on various noctuidae pests.

Pesticidal mixtures comprising as active compounds A) the ethylsulfone compound of formula (I) and B) at least one further compound B selected from fipronil, lambda-cyhalothrin, bifenthrin, tefluthrin, alpha-cypermethrin, thiamethoxam, clothianidin, acetamiprid, imidacloprid, dinotefuran, tri-flumezopyrim, fenmezoditiaz, spinosad, spinetoram, abamectin, afidopyropen, indoxacarb; met-aflumizone, spiropidion, spidoxamat, chlorantraniliprole, cyantraniliprole, tetraniliprole, cyclaniliprole, broflanilide, isocycloseram; dimpropyridaz; and difenoconazole, prothioconazole, flutriafol, ipconazole, tebuconazole, mefentrifluconazole, triticonazole, fluoxytioconazole, metyltetraprole, azoxystrobin, trifloxystrobin, pyraclostrobin, sedaxane, penflufen, fluopyram, fluxapyroxad, pydiflumetofen, isoflucypram, cyclobutrifluram, oxathiapiprolin, fluoxapriprolin, metalaxyl, picarbutrazox, fludioxonil, thiophanat-methyl; methods and use of these mixtures for combating invertebrate pests such as insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially also for protecting plant propagation material as like seeds.

This invention relates to a method of controlling, limiting or preventing an infestation of a plant by Oomycetes, which comprises applying to propagation material of said plant, a pesticidal combination comprising a phosphorus-based compound as active ingredient A, and an active ingredient B selected from acibenzolar-S-methyl, fludioxonil, fluxapyroxad, inpyrfluxam, mefentrifluconazole, prothioconazole, sedaxane, triticonazole, oxathiapiprolin, fluoxapiprolin, azoxystrobin, difenoconazole, fluopyram, ipconazole, metyltetraprole, silthiofam, dimethomorph, thiophanate-methyl, natamycin, benzovindiflupyr, pydiflumetofen, picarbutrazox, isocycloseram, cyclobutrifluram, broflanilide, thiamethoxam, imidacloprid, clothianidin, cyantraniliprole, chlorantraniliprole, tetraniliprole, fipronil, and any mixture thereof.

The invention belongs to the technical field of pesticide disinfestation, and discloses an insecticidal composition containing an amide insecticide and application thereof.The active ingredient of the insecticidal composition comprises an active ingredient A and an active ingredient B. The active ingredient A is a compound shown in the formula I, and the active ingredient B is the amide insecticide. The amide pesticide is any one of tolfenpyrad, cyhalodiamide, tetrachlorantraniliprole, polyflubendiamide, thiotraniliprole and thiodicyclaniliprole, and the compound pesticide is a compound of the following components in parts by weight; the mass ratio of the active component A to the active component B is (1: 40)-(40: 1). According to the insecticidal composition, the insecticidal effect is greatly improved, the utilization rate of the insecticide is increased, the development of insecticide resistance of pests is slowed down, and the service life of the insecticide is prolonged.

The present application relates to a synergistic composition containing a biologically effective amount of compound A and component B, wherein the component B is one of thiazide ketone, avermectin, spirotetramat, pyridalyl, emamectin benzoate, azamethiphos, azocyclotin, pyridaben, quimacryd thiocyl, pyrimidifen, tebufenpyrad, flufenoxuron, chlorfenapyr, cyromazine, and halofenozide, and a method thereof for controlling pests in agronomic and non-agronomic environments. The compound A has a synergistic effect with the component B, which can improve the pest control effect, reduce the application amount, reduce the use frequency, and reduce the use cost.

The invention relates to the technical field of pesticides, and provides an insecticidal composition containing ethiprole and cyantraniliprole, the insecticidal composition is composed of an active component and an auxiliary material, the auxiliary material comprises a dispersant, the dispersant comprises fatty alcohol-polyoxyethylene ether and dimethyl 5-hydroxyisophthalate, the active component accounts for 20% of the mass of the insecticidal composition, and the auxiliary material accounts for 20% of the mass of the insecticidal composition. According to the present invention, the active components comprise ethiprole and cyantraniliprole, and by using the technical scheme, the problems of poor dispersibility and poor prevention and control effect of the insecticidal composition containing ethiprole and cyantraniliprole in the prior art are solved.

The application discloses a new crystal form of brofenvalerate, a preparation method and application thereof. The new crystal form of brofenvalerate comprises a powder X-ray diffraction spectrum expressed by 2θ±0.2° diffraction angle, and the powder X-ray diffraction spectrum shows characteristic peaks at 8.70, 9.94, 11.24, 12.24, 22.38 and 24.70. Compared with the existing crystal form of brofenvalerate, the new crystal form of brofenvalerate discovered by the application has a simple preparation method, more excellent properties and higher biological activity, and can be used for the prevention and control of pests of the orders Lepidoptera, Hemiptera, Coleoptera, Thysanoptera, Hymenoptera, Acarina and Diptera.

The present invention belongs to the field of pesticide insecticide technology and discloses an insecticidal composition and its use. The insecticidal composition comprises active ingredients A and B, wherein the active ingredient A is a compound represented by Formula I; the active ingredient B is any one of tetrazolyl fenpropiamide, cyclobromofenapyr, cyantraniliprole, flufenapyr, chlorfenapyr, or flubendiamide; and the mass ratio of active ingredient A to active ingredient B is 1:45 to 45:1. The insecticidal composition of the present invention rationally combines compounds with different mechanisms of action to produce a synergistic effect, thereby improving pest control effectiveness, reducing the application rate, reducing the number of applications, and lowering the cost of use.

The present application relates to a kind of insecticidal composition and its application, it is related to the field of pesticide, the effective component of insecticidal composition includes carbamate compound and amide insecticide, and its weight ratio is (1-50) :(1-50);The carbamate compound is selected from one or several of thiodicarb, fenobucarb, fenoxycarb and propetamphos;The amide insecticide is selected from one or several of broflan, cyhalofop-butyl, chlorantraniliprole;Carbamate compound of the present application can be used as the internal absorption of amide insecticide Conducting agent, greatly improve the absorption and transmission amount of amide insecticide in crop, improve the insecticidal effect of amide insecticide, improve the utilization rate of pesticide, reduce environmental pollution.

The invention discloses a method for synthesizing a cyantraniliprole impurity. The chemical name of the impurity is 3-bromo-1-(3-chloro-2-pyridyl)-N-[4-(formamido)-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-hydrogen-pyrazole-5-carboxamide. 2-amino-3-methylbenzoic acid is used as a starting material, and the product is sequentially subjected to triphosgene cyclization, nitration, amine transesterification ring-opening, hydrogenation reduction, and two-step amide condensation reactions to finally obtain a target compound, 3-bromo-1-(3-chloro-2-pyridyl)-N-[4-(formamido)-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-hydrogen-pyrazole-5-carboxamide. The whole reaction route has simple conditions, is easy to operate, and is economical and practical.

The present invention belongs to the field of pesticide insecticide technology and discloses an insecticidal composition containing an amide insecticide and its use. The active ingredients of the insecticidal composition include active ingredient A and active ingredient B, wherein active ingredient A is a compound represented by formula I; active ingredient B is an amide insecticide, and the amide insecticide is any one of tolfenpyrad, chlorfluanid, tetrachlorantraniliprole, polyflubenzuron, sulfanilamide, and sulfenylamide; and the mass ratio of active ingredient A to active ingredient B is 1:40 to 40:1. The insecticidal composition of the present invention significantly improves insecticidal efficacy, increases the utilization rate of the pesticide, slows the development of pest resistance, and extends the service life of the pesticide.

The present invention belongs to the field of pesticide insecticide technology and discloses an insecticidal composition and its use. The active ingredients of the insecticidal composition include active ingredient A and active ingredient B. Active ingredient A is a compound of formula I: #imgabs0#, and active ingredient B is a diamide compound, including any one of flubendiamide, flubendiamide, thiobencarb, chlorocyanamide, and tetrachlorfenapyr. The mass ratio of active ingredient A to active ingredient B is 1:40 to 40:1. The insecticidal composition of the present invention can effectively control lepidopteran pests such as diamondback moth, cabbage looper, and rice stem borer, and has the advantages of significant synergistic effect, expanded insecticide spectrum, reduced application amount, and crop safety.

The invention relates to a method for simultaneously preparing cyantraniliprole metabolites IN-K5A78 and IN-JSE76, and belongs to the technical field of pesticide metabolites. The preparation method comprises the following steps: by taking cyantraniliprole as a raw material, firstly carrying out acidic hydrolysis on cyano and then carrying out methyl esterification to obtain an intermediate 1; then carrying out a reaction under an alkaline condition to obtain a mixed solution of cyantraniliprole metabolites IN-K5A78 and IN-JSE76; the method comprises the following steps: respectively separating cyantraniliprole metabolites IN-K5A78 and IN-JSE76 from a mixed solution by adjusting the pH (Potential of Hydrogen) of the mixed solution, so as to obtain the cyantraniliprole metabolite IN-K5A78 and the cyantraniliprole metabolite IN-JSE76. The two cyantraniliprole metabolites can be prepared at the same time, the atom utilization rate of the raw materials is extremely high, and the two cyantraniliprole metabolites can be separated only by simply adjusting the pH of the reaction liquid after the reaction is finished. The method realizes large-scale preparation of cyantraniliprole metabolites, and meets the sample requirements of pesticide registration.

The present invention relates to new solid forms of cyantraniliprole, processes for its preparation, and agrochemical compositions thereof.

A synergistic insecticidal composition comprising (A) isothiazolyl amide; (B) one insecticide selected from the group consisting of chlorantraniliprole, cyantraniliprole, cyclaniliprole, tetraniliprole, pyridalyl, pymetrozine, chlorfenapyr, sulfoxaflor, flubrocythrinate, sulfoxaflor; and (C) one or more insecticides selected from the given list. The invention also relates to a process for the preparation of said composition in specific amounts. The invention also relates to a process for the preparation of said composition together with at least one formulation excipient, and to the formulation of said composition. The invention also relates to a synergistic composition, wherein the active ingredients present in fixed amounts exhibit a synergistic effect in terms of insecticidal activity.

The application belongs to the technical field of pesticide insecticide, and discloses a kind of insecticide composition and its application, the active ingredient of the insecticide composition active ingredient includes active ingredient A and active ingredient B, the active ingredient A is formula I compound: the active ingredient B is any one of flubrocythrinate, tetrahydrochloride amide, bromocyclen amide, chlorobenzamide, tetrachloride amide, cyclo-bromide amide, fluorine benzene amide, amide, chlorofluoro cyanide amide, the mass ratio of the active ingredient A and active ingredient B is 1:55~50:1.The insecticide composition has excellent control effect on pests.

The present invention relates to a composition comprising components (A) and (B) as active ingredients, wherein component (A) comprises a Streptomyces chrestomyceticus and component (B) is a compound selected from the group consisting of prothioconazole, difenoconazole, mefentrifluconazole, hexaconazole, propiconazole, bromuconazole, fenpropidin, spiroxamine, isoprothiolane, pydiflumetofen, benzovindiflupyr, isoflucypram, isopyrazam, fluxapyroxad, cyprodinil, azoxystrobin, pyraclostrobin, metyltetraprole, proquinazid, tricyclazole, florylpicoxamid, fenpicoxamid, N-(2,4-dimethyl-1-phenylpentan-2- yl)-8-fluoroquinoline-3-carboxamide, ipflufenoquin, quinofumelin, zinc thiazole, folpet, chlorothalonil, acibenzolar-S-methyl, fosetyl- aluminium, oxolinic acid, anisiflupurin, inpyrfluxam, metalaxyl, metalaxyl-M, triticonazole, penthiopyrad, sedaxane, thiabendazole, imidacloprid, thiamethoxam, fludioxonil, fluoxastrobin, silthiofam, chlorantraniliprole, ethaboxam, ipconazole, cyantraniliprole, oxathiapiprolin, fluopyram, picarbutrazox, cyclobutrifluram, isocycloseram, and fluoxapiprolin. The invention further relates to a method of controlling or preventing phytopathogenic diseases, preferably phytopathogenic fungi, on a plant or on plant propagation material and / or on harvested food crops, which comprises applying to the plant, on plant propagation material, the locus thereof, and / or on harvested food crops the composition according to the present invention.

A mixture for killing pests, comprising, as the active compound, A) an ethyl sulfone compound having formula (I) and B) At least one additional compound B, selected from fipronil, λ-cyhalothrin, bifenthrin, heptafluthrin, α-cyhalothrin, thiamethoxam, thiamethoxam, acetamiprid, imidacloprid, dinotefuran, trifluralin, dithiamethoxam, spinosad, ethyl spinosad, abamectin, bispyribac-methyl, indoxacarb; cyfluthrin, methoxypiperazine ethyl ester, dispirenil, chlorantraniliprole, brofenoxuronamide, tetrazolium acetonitrile, cyclobromhizobium acetonitrile, brofenoxuron dimethoate; pyrimethanil, M.UN.1: 1-[6-(2,2-difluoro-7-methyl-[1,3]m-dioxacyclopenten[4,5-f]benzimidazol-6-yl)-5-ethylsulfonyl-3-pyridyl]cyclopropaneformonium, M.UN.2: 6-(5-cyclopropyl-3-ethylsulfonyl- 2-pyridyl)-2,2-difluoro-7-methyl-[1,3]m-dioxacyclopenten[4,5-f]benzimidazole; and difenoconazole, prothioconazole, fenbendazole, tebuconazole, chlorfluazuron, cymoxanil, fluopyram, tetrazoxystrobin, azoxystrobin, oxadiazon, azoxystrobin, fluopyram, fluopyram, fluopyram, fluopyram, fluopyram, isopropoxystrobin, trifluoropyridamole, fluthiazolinone, flusaprolin, metalaxyl, tetrazoxystrobin, fludioxonil, thiophanate-methyl; these mixtures are used to combat invertebrate pests such as insects, arachnoides or nematodes inside and on the surface of plants, and for the protection of such plants, especially for the protection of plant propagation material such as seeds from pest infestation.