391 results about "Naphthoic acid" patented technology

The invention provides certain nicotine salts, co-crystals, and salt co-crystals and provides novel polymorphic forms of certain nicotine salts. In particular, nicotine salts with mucic acid, 3,5-dihydroxybenzoic acid, and 2,3-dihydroxybenzoic acid, and crystalline polymorphic forms of nicotine 4-acetamidobenzoate, nicotine gentisate, and nicotine 1-hydroxy-2-naphthoate are described. The invention further provides methods of preparation and characterization of such nicotine salts, co-crystals, and salt co-crystals and polymorphic forms thereof. In addition, tobacco products, including smoking articles, smokeless tobacco products, and electronic smoking articles comprising nicotine salts, co-crystals, and/or salt co-crystals are also provided.

An aromatic liquid-crystalline polyester having a small dielectric loss in a wide frequency region is provided. An aromatic liquid-crystalline polyester is provided that can manufacture a film having a small volume expansion by heating. An aromatic liquid-crystalline polyester substantially comprising a repeating structural unit originating in 2-hydroxy-6-naphthoic acid 30 to 80 mol %, a repeating structural unit originating in aromatic diol 35 to 10 mol %, and a repeating structural unit originating in aromatic dicarboxylic acid 35 to 10 mol %.

The invention relates to the discovery that specific adamantyl or adamantyl group derivatives containing retinoid-related compounds induce apoptosis of cancer cells and therefore may be used for the treatment of cancer, including advanced cancer. Also, the present invention relates to novel adamantyl or adamantyl group derivatives containing retinoid compounds and their usage for treatment and/or prevention of cancer, keratinization disorders, dermatological conditions, and other therapies More specifically, it has been shown that such adamantyl compounds, e.g., 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid, 2-[3-(1-adamantyl)-4-methoxyphenyl]-5-benzimidazole carboxylic acid, and 6-[3-(1-adamantyl)-4,5-methylenedioxyphenyl]-2-naphthoic acid, can be used to treat or prevent cervical cancers and precancers such as cervical dysplasias, including high grade and low grade dysplasias.

The invention discloses a vitamin K2 and preparation process thereof. According to the process, 1-hydroxyl-2-naphthoic acid resistant flavobacterium strain HNA12-D is fermented and cultured, and vitamin K2 efficiently metabolizes in the strain through the batch feeding of glycerin serving as the carbon source, peptone serving as the nitrogen source and precursor substances, and is extracted by using organic solvents and separated by macroporous resin, and the yield and purity of the product are improved. The total output of the vitamin K2 crude product is 200-600 mg/L after the flavobacterium strain HNA12-D of the invention is fermented and cultured for 120-144 hours, and the product purity reaches 80-99 percent after absorption chromatography; compared with the prior art, the yield output and the product purity are greatly improved, and the product can be used in industrial production.

A controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable release speed over a long period of time is provided. A controlled release composition comprising (1) a physiologically active substance or salt thereof in an amount of about 14% (w/w) to about 24% (w/w) based on the total composition weight, (2) hydroxynaphthoic acid selected from the group consisting of 3-hydroxy-2-naphthoic acid and 1-hydroxy-2-naphthoic acid or salt thereof, and (3) a lactic acid polymer or salt thereof having a weight-average molecular weight of 15000 to 50000 in which the content of polymers having molecular weights of 5000 or less is about 5% by weight or less, wherein the molar ratio of said hydroxynaphthoic acid or salt thereof to said physiologically active substance or salt thereof is from 3:4 to 4:3.

A peptide clearing agent is provided for clearance of a conjugate of an enzyme and a binding molecule which binds specifically at a target location from a non-target location in a subject. The peptide clearing agent binds the active site of the enzyme. The peptide also binds to the asialoglycoprotein receptor expressed by hepatic cells to facilitate clearance through the liver. The peptide may be glycosylated to facilitate clearance through the liver by binding to hepatic cells expressing an asialoglyco-protein receptor. Typically, the peptide prevents or inhibits enzyme activity upon binding to the enzyme and is not substantially modified by the enzyme activity. The peptide may be based upon the dipeptide amino-naphthoic acid (ANA)-glutamate (GIu) and may comprise the amino acid sequence serine (Ser)-Alanine (Ala)-amino-naphthoic acid (ANA)-glutamate (GIu). In such cases, the enzyme of interest is typically CPG2.

The invention relates to a preparation method of a graphene/thermotropic liquid crystal wholly aromatic polyester composite material. According to the invention, 6-alkyl-2-naphthoic acid non-covalent bond modified graphene oxide is obtained through the pi-pi interaction of the naphthalene ring structure of 6-alkyl-2-naphthoic acid and graphene oxide, and the modified graphene oxide is subjected to hot reduction in the polycondensation process of a wholly aromatic polyester monomer to generate graphene, so that the graphene is uniformly dispersed in the thermotropic liquid crystal wholly aromatic polyester resin, thus overcoming the problems that the graphene is difficult to disperse and the lamellar structure is easy to agglomerate when the graphene is directly blended with the thermotropic liquid crystal wholly aromatic polyester. After being processed into fiber, the prepared composite resin has favorable conductivity and mechanical performance. Tests prove that the composite material has stable mechanical performance, the strength of the fiber formed by spinning the composite material is increased by 60% or so in comparison with the simple thermotropic liquid crystal wholly aromatic polyester, the fiber has favorable conductivity, and the mechanical performance of the fiber is even superior to that of the simple TLCP (thermotropic liquid crystal polymer) fiber.

A resin composition comprising an inorganic material with a thermal conductivity of 10 W/mK or higher at a temperature of 20° C. and an aromatic polyester is provided. The aromatic polyester may have structural units derived from (I) 2-hydroxy-6-naphthoic acid, (II) a compound selected from hydroquinone, 4,4′-dihydroxybiphenyl and 2,6-dihydroxynaphthalene, (III) naphthalenedicarboxylic acid and (IV) a compound selected from terephthalic acid, isophthalic acid and phthalic acid.

A multi-layer stretched film has 251 or more alternating layers which consist of first layers and second layers, wherein the first layers are made of a polyester which contains (i) 5 to 50 mol % of a naphthoic acid component as a dicarboxylic acid component and (ii) a diol having an alkylene group with 2 to 10 carbon atoms as a diol component; and the second layers are made of a thermoplastic resin having an average refractive index of 1.50 to 1.60 and differences in refractive index among a uniaxial stretching direction, a direction orthogonal to the uniaxial stretching direction and a film thickness direction of 0.05 or less before and after stretching, and the film has specific reflectance characteristics for a P polarization component and an S polarization component.

The present invention provides a class of thermotropic liquid crystalline polyesters (TLCPs) and molding compositions comprising the polyesters and glass fiber. The TLCPs consist essentially of repeat units derived from p-hydroxybenzoic acid (HBA), 6-hydroxy-2-naphthoic acid (HNA), terephthalic acid (TA), and hydroquinone (HQ), and the mole percent of HBA, HNA, TA and HQ is 34-72%, 12-26%, 4-21% and 4-21%, respectively. The TLCPs have a melting temperature equal to or below 355° C., an inherent viscosity of 4.0-10.0 dL/g and a Heat Deflection Temperature (HDT) in the range of 260-285° C. when compounded with 30% by weight glass fiber. The optimum compositions, selected from the above-mentioned compositional ranges exhibit a relatively low melting temperature and a relatively high HDT. Specified compositions, selected from the above-mentioned compositional ranges have low melting point, which are useful to blend with conventional polymers such as poly (ethylene terephthalate) and nylon etc.

A multilayered reflective polarizing film is provided that has high polarization performance comparable to that of an absorption-type polarizing plate, and is preferred as a polarizing plate attached to a liquid crystal cell. An optical member for liquid crystal display devices, and a liquid crystal display device formed from such a multilayered reflective polarizing film are also provided. Specifically, the reflective polarizing film includes a uniaxially stretched multilayered film in which a specific aromatic polyester containing (alkylenedioxy)di-2-naphthoic acid as a part of dicarboxylic acid components is used as a first layer, and an optically isotropic polyester having an average refractive index of 1.50 to 1.60 is used as a second layer, and that has a predetermined refractive index difference between the layers. The reflective polarizing film has an angle of orientation of 2 degrees or less.

The invention belongs to the field of a rare earth-polymer composite luminescent material, and specifically relates to a luminescent material of naphthoic acid functionalized polymer and rare earth complex and a preparation method of the luminescent material. In the preparation method, a naphthalene acid ligand with coordination and sensitization dual-function roles on rare earth ions is introduced into a polymer side group; and the ligand not only can form stable polymer-rare earth complex together with the rare earth ions, but also has a large conjugate rigid plane, can greatly enhance energy transfer action of the polymer ligand on the rare earth ions, and enhances the luminescence property. The method disclosed by the invention not only is easy to achieve, but also solves the problems that the rare earth complex in the prior art has dispersion inequality and poor polymer substrate performance.

The invention relates to a synthesizing method of nafcillin sodium-hydrate. 2-hydroxy-1-naphthoic acid is adopted as the initial raw material to be ethylized to obtain 2-ethyoxyl-1-ethyl naphthalene, the 2-ethyoxyl-1-ethyl naphthalene is hydrolyzed, chloridized and is coupled with 6-APA to obtain the nafcillin acid, and the nafcillin acid is salified in the mixed solution of acetone of sodium bicarbonate or sodium carbonate to directly prepare the target product nafcilin sodium-hydrate. The product prepared with the method has low cost, is easy to obtain the raw materials, has simple process, and is easy to control the residual solvent. The content is me than 99.5 percent. The product is applicable to the industrialized production.

A liquid potting composition, a semiconductor device manufactured using such composition and a process for manufacturing a semiconductor device using such composition. The liquid potting composition comprises: (a) a liquid epoxy resin; (b) a hardener comprising a multi-hydroxy aromatic compound containing at least two hydroxy groups and at least one carboxyl group; and (c) an accelerator. Suitable hardening agents include 2,3-dihydroxybenzoic acid; 2,4-dihydroxybenzoic acid; 2,5-dihydroxybenzoic acid; 3,4-dihydroxybenzoic acid; gallic acid; 1,4-dihydroxy-2-naphthoic acid; 3,5-dihydroxy-2-naphthoic acid; phenolphthaline; diphenolic acid and mixtures thereof.

Stable pharmaceutical/cosmetic compositions for topical application, notably for the treatment of acne vulgaris include, formulated into a physiologically acceptable medium, at least one naphthoic acid compound, benzoyl peroxide and at least one film-forming agent, the at least one naphthoic acid compound and the benzoyl peroxide advantageously being in a dispersed form therein.

The invention belongs to the field of rare earth-macromolecule complex luminescent materials, and particularly relates to a bonding type polymer-rare earth ternary complex luminescent material and a preparation method thereof. The bonding type polymer-rare earth ternary complex luminescent material is prepared by coordinating rare earth ions with polymer of bonded naphthoic acid ligand serving as a macromolecule ligand and any one of naphthoic acid, phenanthroline, and 2,2'-diphridyl serving as a micromolecule ligand. Not only is the method easily realized, but also the performances of the material prepared can be greatly improved, the problems in the prior art that the rare earth complex are uneven to disperse, poor in performances of polymer matrix and the like can be solved, and the bonding type polymer-rare earth ternary complex luminescent material and the preparation method thereof can develop a new way for preparing novel rare earth-macromolecule complex luminescent materials.

The invention provides a liquid crystal polymer which is prepared by polycondensing para-hydroxybenzoic acid, 2,6-naphthalic acid, 6-hydroxy-2-naphthoic acid and 4,4-dihydroxybenzophenone. The invention also provides a preparation method of the liquid crystal polymer. Besides, the invention also provides liquid crystal polymer composite materials containing the liquid crystal polymer. The melting point of the liquid crystal polymer is moderate, and the processing temperature range is widened; and ketone characteristic groups are introduced into the polymer chain, thereby enhancing the comprehensive mechanical properties of the polymer. Further more, the preparation method of the liquid crystal polymer is simple, has the advantage of easily controlled reaction end point, and can ensure the reproducibility of the polymer quality. In addition, the liquid crystal polymer can be used as a resin for preparing multiple liquid crystal polymer composite materials.

Cosmetic/dermatological compositions for topical application and useful for the treatment, e.g., of acne, contain, formulated into a physiologically acceptable medium, at least one naphthoic acid compound and at least one polyurethane polymer or derivative thereof, the at least one naphthoic acid compound being dispersed therein.