The invention discloses a waste gas integrated treatment device which comprises the following five systems: a waste gas collection and discharge system, a waste gas oxidation and absorption-adsorption system, a waste gas alkalization and absorption-adsorption system, an ozone generation system, and an electric control system. Waste gas is absorbed into the oxidation and absorption-adsorption system through a blower fan, is oxidized by ozone and adsorbed by active carbon, then enters the alkalization and absorption-adsorption system, is absorbed by alkali liquor and adsorbed by active carbon, and is discharged through an exhaust funnel. The device can effectively treat organic and inorganic waste gas containing components such as benzene, toluene, butanone, acetic ether, styrene, hydrogen sulfide, ammonia, methyl mercaptan, sulfur dioxide, dimethyl sulfide, acrylic acid, and the like, effectively remove dust particles, solve atmosphere pollution caused by waste gas sources of production workshop, sewage biochemical aeration tank, and the like, realize standard waste gas discharge, and has purification performance technical indexes which reach the domestic advanced level.