41 results about "Oxidative decarboxylation" patented technology

The invention discloses a synthetic method of 3, 4-methylene dioxybenzaldehyde and relates to the field of chemical organic synthesis, and particularly relates to a synthetic method in which an intermediate generated in a process of preparing 3, 4-methylene dioxybenzaldehyde by taking catechol methylene ether as a raw material is oxidized by suing a nitryl-free oxidizing agent to generate the final product. According to the synthetic method of 3, 4-methylene dioxybenzaldehyde, oxidative decarboxylation is carried out on the intermediate piperonyl mandelic acid (prepared from catechol methylene ether) as an initial reactant in the presence of at least one catalyst selected from metal chloride Lewis acid and at least one oxidizing agent selected from oxygen and peroxides in an acidic environment so as to synthesize 3, 4-methylene dioxybenzaldehyde. The synthetic method provided by the invention is simple in technical step, thorough in conversion of the raw materials, high in finished product yield and short in technical time, and the product does not contain color-changing impurities and is stable in technical quality.

The invention relates to a preparation method of 4-acetyloxy-2-azetidinone compounds, and is used for solving the problem that the large-scale industrial production cannot be favorably realized because of defects such as severe reaction condition, complex treatment process, high cost, serious environment pollution and the like in the prior art. The method provided by the invention comprises the step of carrying out oxidization deacidification in the existence of a dehydrating agent N, N'-dicyclohexylcarbodiimide and an oxidizing agent peroxyacetic acid by taking 4-carboxyl-2-azetidinone compounds I as raw materials to obtain the 4-acetyloxy-2-azetidinone compounds II. A heavy metal oxidizing agent or catalyst is prevented from being used in the oxidization deacidification process, so that the residue and discharge of heavy metals and environmental pollution caused by the heavy metals are greatly reduced. Byproducts generated in a reaction process can be conveniently recycled, so that the production cost is reduced to the great extent, and the preparation method is more excellent on the aspect of economical efficiency. The method is mild in reaction condition, simple and convenient to operate and suitable for large-scale production; the 4-acetyloxy-2-azetidinone compounds are easy to separate and purify and high in yield.

The invention relates to a method for synthesizing an arylseleno-heterocyclic compound. The method comprises the following step: in an organic solvent, under an oxygen condition, by taking heterocyclic aromatic carboxylic acid and diaryl diselenide ether as reaction raw materials, and under the cooperative promotion action of a copper catalyst, a ligand and alkali, performing oxidative decarboxylation coupling reaction, thereby obtaining the arylseleno-heterocyclic compound. By adopting the method, the substrate, namely the heterocyclic aromatic carboxylic acid, and the copper catalyst are cheap and easy to obtain, the substrate range is wide, reaction conditions are simple, the yield and the purity of the product are high, novel synthesis routes and methods are developed for arylseleno-heterocyclic compounds, and the method has good application potentials and study values.

The invention provides a preparation method of glyphosate polymer, in particular to a N-(Phosphonomethyl)iminodiaceticacid catalytic polycondensation method. The preparation method comprises the following steps of: mixing and conditioning proguanil hydrochloride, sulfuric acid and a catalyst into slurry, wherein the catalyst is a compound selected from sodium bisulfate, potassium bisulfate, ammonium hydrogen sulfate and tripolyphosphate; heating the slurry for carrying out an oxidative decarboxylation reaction until no bubble is generated; and adding one of catalysts and uniformly mix with the slurry after the oxidative decarboxylation reaction and heating the uniformly mixed slurry for carrying out a polycondensation reaction until the reaction is finished. The glyphosate polymer of the invention is used for weeding and has the advantages of high efficiency, durability and slow release effect.

The invention relates to a synthetic method of an aryl methyl selenide compound. In an organic solvent, under the oxygen condition, aryl carboxylic acid and dimethyldiselenide are used as reaction raw materials to obtain the aryl methyl selenide compound through oxidative decarboxylation coupling reaction under the joint promoting effect of a copper catalyst, a ligand and alkaline. The aryl carboxylic acid and the copper catalyst adopted in the method are cheap and easy to obtain, a substance range is wide, the reaction condition is simple, the product yield and purity are high, a new synthetic route and method is developed for the aryl methyl selenide compound, and the aryl methyl selenide compound has good utilization potential and a research value.