115 results about "Thiazoline" patented technology

The invention discloses a method for detecting glufosinate-ammonium residues in coffee in dual modes of colorimetry and chemiluminescence, and belongs to the technical field of chemical analysis and detection.The method comprises the steps that Schiff base formed by 4-aminoantipyrine and glutaraldehyde serves as a complexing agent of Cu < 2 + >, and then a copper-doped carbon dot Cu-CDs nano-enzyme is prepared through microwave digestion; according to the present invention, the Cu-CDs nano-enzyme has excellent peroxidase-like activity, can oxidize the colorless 2, 2 '-biazo-bis-3-ethylbenzothiazoline-6-sulfonic acid into the blue-green oxidized ABTS, and can improve the chemiluminescence intensity of the reaction of N-(4-aminobutyl)-N-ethylisoluminol and H2O2 by nearly 100 times when the Cu-CDs nano-enzyme is used as the chemiluminescence catalyst; based on the inhibition effect of glufosinate-ammonium on the activity of Cu-CDs POD, a sensitive and rapid colorimetric and chemiluminescence two-channel GM detection technology is developed, and the method has potential application value in the aspect of coffee safety monitoring.

The present disclosure is directed to a preservative composition comprising a linear polyetheramine having a molecular weight greater than 118 Daltons (Da) and at least one isothiazolinone, whereby this preservative composition may further comprise a pyrithione salt and / or a metal salt. Also disclosed is an aqueous industrial material comprising the preservative composition as well as a method for enhancing in-contaniner preservative performance of an aqueous industrial material using the preservative composition.

The invention discloses an isothiazolinone non-curing coating and a preparation method thereof, and relates to the technical field of waterproof coatings. The coating comprises a base material, a compound isothiazolinone antibacterial agent, a mixed stabilizer, a compound plasticizer, a compound anti-aging agent, a filler, an adhesion promoter and a solvent, the compound type isothiazolinone antibacterial agent is prepared by mixing and compounding 2-methyl-4-isothiazolin-3-ketone and 5-chloro-2-methyl-4-isothiazolin-3-ketone according to a mass ratio of (1 to 3): 1, and the compound type isothiazolinone antibacterial agent is prepared by mixing and compounding 2-methyl-4-isothiazolin-3-ketone and 5-chloro-2-methyl-4-isothiazolin-3-ketone and 5-chloro-2-methyl-4-isothiazolin-3-ketone; the mixed stabilizer is formed by mixing organic bentonite, polyamide wax and fumed silica; the defects that an existing non-curing coating is poor in antibacterial performance, insufficient in aging resistance and poor in formula compatibility are overcome.

The invention provides a method for preparing a storage-resistant water-insoluble isothiazolinone, and belongs to the technical field of chemical synthesis. The invention first uses N,N'-di-n-octyl dithiodipropionamide, a chlorinated solvent and chlorine as raw materials for chlorination reaction to prepare 2-n-octyl isothiazolin-3-ketone OIT and / or 4,5-dichloro-2-n-octyl isothiazolin-3-ketone DCOIT finished products with less impurity content, thereby reducing the discoloration reaction caused by impurities; the product is then mixed with a stabilizer, and the inhibitory effect of the stabilizer on the free radical discoloration process is utilized to finally obtain a storage-resistant water-insoluble isothiazolinone, thereby solving the problem of discoloration of the water-insoluble isothiazolinone during storage.

The invention discloses a quaternary ammonium salt type composite algaecide for preventing and controlling harmful algae in a reservoir water body and a preparation method of the quaternary ammonium salt type composite algaecide. According to the preparation method, gemini quaternary ammonium salt (dichlorinated 1, 1 '-([1, 1'-biphenyl]-4, 4 '-diyl) bis (N-benzyl-N, N-dimethyl ammonium), dichlorinated N, N'-([1, 1 '-biphenyl]-4, 4'-diyl bis (methylene)) bis (N, N '-(1, 1'-biphenyl]-4, 4 '-diyl bis (methylene)) is utilized to react with N, N'-(1, 1 '-biphenyl]-4, 4'-diyl) bis (N-benzyl-N, N- According to the present invention, N, N-dimethylpyridine-4-amine), dodecyl dimethyl benzyl ammonium bromide, dodecyl dimethyl benzyl ammonium chloride, hexadecyl dimethyl benzyl ammonium chloride, benzalkonium chloride, isothiazolinone and derivatives thereof are respectively subjected to synergistic algal inhibition, and are used for inhibiting common algal blooms in reservoir water. The quaternary ammonium salt type composite algaecide has a higher removal rate on harmful algae (such as microcystis aeruginosa) in a water body of a reservoir, can effectively control water bloom caused by the harmful algae in the water body, and is simple to prepare and good in algae removal effect.

The invention belongs to the technical field of stripping agents, and particularly relates to a slime stripping agent and a preparation method and application thereof. The slime stripping agent disclosed by the invention is prepared from dodecyl dimethyl benzyl amine bromide, dichlorophenol, isothiazolinone, polyoxyethylene alkylolamide, hydroxyethylidene diphosphonic acid, dimethylformamide and sodium dodecyl benzene sulfonate. Through the combined action of the specific components, the slime stripping agent has good stripping capacity and can rapidly permeate and disintegrate slime, dirt and biological membranes attached to the surface of equipment, the cleanliness and operation efficiency of the equipment are recovered, and equipment blockage and performance reduction caused by slime accumulation are effectively avoided; meanwhile, the high killing effect on sulfate reducing bacteria and nitrifying bacteria is achieved.

The invention relates to the technical field of oxygen free radical detection, in particular to a manufacturing process of a portable and reliable oxygen free radical detector. Comprising the following steps: mixing superoxide dismutase, potassium ferricyanide, an isothiazolinone preservative, hexammine ruthenium chloride, polyethylene glycol octylphenol ether, trehalose and bovine serum albumin, and uniformly stirring to prepare an enzyme preparation; mixing an enzyme preparation with the high polymer material solution to form reagent layer slurry with viscosity; uniformly coating the reagent layer slurry on a substrate material, and drying; printing an electrode material on the substrate material to form a working electrode and a counter electrode; the silver electrode is placed in an electrolyte containing chloride ions, potential is applied, the silver surface is subjected to a chlorination reaction, and a silver / silver chloride electrode is formed; covering the reagent layer above the electrode, tightly combining the reagent layer with the electrode in a sticking or hot pressing manner, and cutting to obtain the test paper; the prepared portable oxygen free radical detector can be used for conveniently and efficiently detecting oxygen free radicals of a human body at low cost.

The invention relates to a green, safe and environment-friendly granulation auxiliary agent for granular urea and a preparation method and application thereof.The granulation auxiliary agent is prepared from 10%-20% of crystalline fructose, 5%-15% of carboxymethyl cellulose, 5%-15% of polyaspartic acid, 0.1%-0.5% of isothiazolinone and 50%-79.9% of purified water. Adding carboxymethyl cellulose in a spreading manner at normal temperature, standing on the water surface, and starting to stir uniformly after absorbing water and swelling for 24 hours, so as to obtain a carboxymethyl cellulose aqueous solution; stirring and completely dissolving the residual purified water, crystalline fructose and polyaspartic acid in another reaction kettle, adding the solution into the carboxymethyl cellulose aqueous solution within 1.5-2.5 hours, and continuously stirring; and finally, adding isothiazolinone, and uniformly stirring to obtain the granulation auxiliary agent. When the granulation aid is used, 0.5-2.0 kg of the granulation aid is pumped into a urea production system by a pressure pump per ton of urea to ensure that the granulation aid is effectively, sufficiently and uniformly mixed with urea melt to play a role in granulation, so that the traditional urea granulation aid formaldehyde is replaced.

The present invention discloses a tubular mixing reactor for producing isothiazolinone in the technical field of tubular mixing reactors, comprising a tubular body, and also comprising an airflow column arranged in the middle of the inner cavity of the tubular body, the airflow is communicated with the inner cavity of the tubular body through the outer wall from one end of the inner cavity of the airflow column, a mixing piece is rotatably connected to the inner wall of the tubular body, an air outlet of the airflow column is arranged at one end of the tubular body, and a transmission mechanism connected to the mixing piece is arranged at the air outlet. By installing the airflow column in the tubular body, it is possible to achieve full mixing of the reaction materials through the porous output of the airflow and the blowing of the reaction materials by multiple airflow points during the transportation of the reaction materials, and at the same time, under the action of the airflow, the external mixing cylinder drives the reaction materials to perform operations such as turning the materials, which greatly improves the ability of the materials required for mixed reaction in the production of isothiazolinone to fully carry out mixed reaction, and the production process is easy to control, reduces energy consumption, and improves production efficiency and the safety factor of the production process.

The invention relates to the technical field of biological control, and discloses an application of steviosin or a substance containing the steviosin in preparation of a nematode control product. According to a caenorhabditis elegans toxicity tracking method, stevia rebaudiana mother liquor sugar is separated according to the polarity of the substance; two compounds are separated and purified from mother liquor sugar by using normal phase silica gel, reverse phase silica gel, LH20 gel and liquid chromatography in sequence, the compounds are identified by using mass spectrum and nuclear magnetism, the compounds are determined to be Steretin F and Steretin E, the Steretin F and the Steretin E are proved to have nematicidal toxicity, the Steretin F has the strongest toxicity, LC50 is 1.57, the toxicity effect is stronger than that of thiazoline and weaker than that of abamectin, and the Steretin F and the Steretin E have the nematicidal toxicity. A new direction is provided for application of stevia rebaudiana, and an important theoretical and practical basis is provided for development and large-scale application of natural insecticidal compounds.

The application discloses a long-acting antibacterial adsorption filler and a preparation method thereof, and comprises the following steps: S1, preparation of composite activated alumina; S2, preparation of aminated composite alumina; S3, preparation of organically modified composite alumina; and S4, preparation of the long-acting antibacterial adsorption filler. The long-acting antibacterial adsorption filler is prepared by loading cerium and bismuth composite oxides on an activated alumina substrate, and then bridging with a silane coupling agent, and sequentially introducing maleic anhydride, 2,3-epoxypropyl trimethyl ammonium chloride and 2-mercaptothiazoline, so that the finally-prepared filler integrates multiple functions such as physical adsorption, chemical adsorption, contact sterilization and slow-release sterilization. The method effectively solves the technical problems of single function of a traditional adsorbent, inability to sterilize and easy secondary pollution, and achieves omnibearing and long-acting purification of indoor air pollutants.

The present invention relates to combinations of a compound of formula (A-1) with a compound selected from the group consisting of dimpropyridaz, emamectin and isocycloseram, bentioflumin, pioxaniliprole, isoflualanam, cybenzoxasulfyl, vinylfluthrin, cyclobunofen, flupymezotiaz, fentiazoluron, 1-(1,2-dimethylpropyl)-5-methyl-N-prop-2-ynyl-N-(3-pyridyl)pyrazole-4-carboxamide, 1 -[4- [5-ethylsulfonyl-1-methyl-4-[3-methyl-6-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]imidazol-2- yl]phenyl]cyclopropanecarbonitrile, [(Z)-[[3-ethylsulfonyl-5-[4-(trifluoromethoxy)phenyl]-2-pyridyl]-[[5- (trifluoromethyl)-2-pyridyl]amino]methylene]amino] acetate, 3-[3-ethylsulfonyl-5-[4- (trifluoromethoxy)phenyl]-2-pyridyl]-4-[5-(trifluoromethyl)-2-pyridyl]-1,2,4-oxadiazol-5-one, 1-(4- chlorophenyl)-2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfanyl)benzene, and emamectin benzoate; and to methods of controlling or preventing damage to plants using such combinations; and to formulations, concentrates and seed treatments comprising such combinations.

The invention relates to a composite electrostatic eliminator and a preparation method thereof, and relates to the technical field of chemical assistants, the composite electrostatic eliminator comprises isopropanol, cetrimonium chloride, fatty alcohol-polyoxyethylene ether, polyvinyl alcohol, polyethylene glycol, triethanolamine, isothiazolinone, propylene glycol, disodium ethylene diamine tetraacetate, essence, modified carbon nanotubes, and a hydrophobic ionic liquid. The water-based polyurethane resin is prepared from water-based furan polyurethane, non-ionic water-based furan polyurethane, bismaleimide and the balance deionized water. Modified carbon nanotubes and hydrophobic ionic liquid are uniformly dispersed in a coating through electrostatic anchoring of cetrimonium chloride and emulsification of fatty alcohol-polyoxyethylene ether, an electron tunneling network in a low-humidity environment is formed, and it is ensured that the electrostatic dissipation capacity of the coating of the electrostatic elimination agent in the low-humidity environment is improved; a dynamic cross-linked network is formed through a Diels-Alder reaction generated by the nonionic waterborne furan polyurethane and the bismaleimide, a conductive path in a damaged area can be rebuilt under external thermal excitation, and the functional durability is improved.

The invention provides a preparation method of 2-mercaptothiazoline, and belongs to the field of organic synthesis.The preparation method comprises the steps that sodium ethyl xanthate is added into alkali liquor, and a mixed solution is obtained; then, slowly dropwise adding a 2-chloroethylamine hydrochloride aqueous solution into the mixed solution, stirring, putting into a microwave reactor, heating to 35-45 DEG C, carrying out heat preservation reaction for a certain time, ending the reaction after TLC monitors that the raw materials disappear, naturally cooling the reacted solution to 25-30 DEG C, stirring, filtering to obtain a 2-mercaptothiazoline crude product, recrystallizing with water, and filtering to obtain the 2-mercaptothiazoline. And carrying out vacuum drying to obtain the purified 2-mercaptothiazoline. The preparation method provided by the invention is simple in step, short in time, low in energy consumption and good in safety, the yield of the obtained 2-mercaptothiazoline product reaches 93.9%, and the purity reaches 99.7%.

This utility model discloses a waste treatment device for isothiazolinone production, relating to the field of isothiazolinone production technology. The waste tank is connected to a first filter, the first filter is connected to a settling tank, the settling tank is connected to a distillation tank, the distillation tank is connected to a degradation tank, the degradation tank is connected to a sedimentation tank, the sedimentation tank is connected to a second filter, the second filter is connected to a nanofiltration membrane device, and the nanofiltration membrane device is connected to a treatment water tank. This device can effectively remove harmful substances from the isothiazolinone production waste, achieving harmless treatment of the waste and also realizing resource recycling to a certain extent, thus possessing good environmental and economic benefits.

The invention relates to the technical field of preservatives, in particular to an isothiazolinone antiseptic decontamination compound and a preparation method of the isothiazolinone antiseptic decontamination compound. The invention relates to a corrosion and scale inhibitor, which is prepared from the following raw materials in percentage by weight: 0.1 to 0.4 percent of isothiazolinone preservatives, 0.06 to 0.15 percent of benzene hydroxyl preservatives, 1 to 2 percent of fatty alcohol-polyoxyethylene ether-9, 0.1 to 0.2 percent of dodecyl dimethyl amine oxide, 0.005 to 0.05 percent of chelating agents, 0.3 to 2 percent of solvents and 95.2 to 98.44 percent of EDI pure water. The sum of the weight percentages of the raw materials is 100%. According to the present invention, the benzene hydroxyl preservative is added as the stabilizer and the synergistic agent, such that the problems of easy degradation, obvious yellowing and weak single corrosion resistance of the isothiazolinone preservative at the high temperature are solved, and the decontamination ability of the product is ensured. The isothiazolinone anti-corrosion decontamination compound disclosed by the invention has excellent anti-corrosion performance and high-temperature stability, and is suitable for being used as an anti-corrosion agent in daily chemical products.

This utility model discloses a pretreatment device for raw materials in the production of high-purity Kathon, relating to the field of Kathon production technology. The inlet of an ultrasonic reactor is connected via pipelines to a methylchloroisothiazolinone raw material tank and a deionized water tank. The outlet of the ultrasonic reactor is connected via a screw pump to a ceramic membrane device. The liquid phase outlet of the ceramic membrane device is connected via pipelines to a distillation column. The top gas phase outlet of the distillation column is connected via pipelines to a light component tank, an organic solvent tank, and a purified methylchloroisothiazolinone tank. This device achieves effective separation and purification of different components, improving product purity, while simultaneously recovering organic solvents and reducing production costs.

Provided is a carbon material dispersion which does not adversely affect other compounding components, is effective on a wide range of microorganisms such as bacteria, molds, and yeasts, and can maintain a high preservative / antibacterial effect and persistence thereof over a long period of time in any environment even if a small amount of the carbon material dispersion is used. Thus, dispersibility and storage stability can be highly considered. Also provided is a slurry composition for a negative electrode for a secondary battery, which uses the dispersion liquid, and which is suitable for the production of a battery / electrode such as a lithium ion battery. This carbon material dispersion liquid contains at least a carbon material containing carbon nanotubes, a dispersant, a preservative, and a liquid medium, and is characterized in that the preservative contains a triazine compound and at least one substance selected from the group A described below. Group A: an iodo-propargyl compound, a pyridine compound, a pyrithione compound, a hydroxyquinoline compound, a benzothiazole compound, an isothiazoline compound, and a dithiol compound.

The invention discloses a wearable sensor-minimally invasive diabetes monitoring patch and a preparation method thereof, and belongs to the technical field of biomedicine, the patch comprises a microneedle array module and a sensing unit; the microneedle array module is composed of a plurality of microneedles arranged in an array; the sensing unit is loaded in the microneedle, and the sensing unit comprises a multi-shell metal organic framework cascade enzyme system and a chromogenic substrate; the multi-shell metal organic framework cascade enzyme system is of a double-layer structure composed of an inner core and an outer shell, the inner core is a metal organic framework packaged with glucose oxidase and modified with carboxyl functional groups, and the outer shell is a metal organic framework packaged with horse radish peroxidase. And 2, 2-nitrogen-bis (3-ethylbenzothiazoline-6-sulfonic acid) is taken as a chromogenic substrate. According to the patch, the catalytic efficiency and the detection accuracy are improved, the stability is improved, the storage and transportation cost is reduced, the low detection limit can be achieved, the requirement for instant blood glucose detection is met, the size is small, and the cost is low.

The invention discloses a rubber composite material with marine antifouling property as well as a preparation method and application thereof, and relates to the technical field of marine fouling organism decay protection materials. The rubber composite material with the marine antifouling property comprises the following components which are blended and vulcanized: rubber, a filler, an antifouling agent, a plasticizer, an activating agent, a scorch retarder, an anti-aging agent, an accelerant and a vulcanizing agent, the antifouling agent comprises a copolymer modified by zwitter-ions and at least one of sodium benzoate, tannic acid, 6-gingerol, capsaicin, sulfobetaine, carboxylic acid betaine, phosphorylcholine, isothiazolinone and zinc pyrithione optionally selected from the group consisting of sodium benzoate, tannic acid, 6-gingerol, capsaicin, sulfobetaine, carboxylic acid betaine, phosphorylcholine, isothiazolinone and zinc pyrithione. The invention solves the three core problems of poor compatibility of an antifouling agent and a rubber matrix, short antifouling period caused by easy loss of the antifouling agent, and difficulty in balancing the antifouling property and mechanical property in the existing marine antifouling rubber material.

The invention discloses a preparation process of 3-hydroxy cephalosporin, which comprises the following steps: (1) under the action of alkali, carrying out sulfonylation reaction on thiazoline enol p-nitrobenzyl ester and p-toluenesulfonyl chloride to obtain a sulfonylation reaction intermediate; (2) carrying out morpholine protection reaction on the sulfonylation reaction intermediate obtained in the step (1) and morpholine under the action of alkali to obtain a morpholine protection intermediate; (3) preparing a feed liquid A from the morpholine protection intermediate and an acid-binding agent, preparing a feed liquid B from a brominating reagent, and simultaneously introducing the feed liquid A and the feed liquid B into a microchannel reactor for continuous reaction to obtain a brominated product; and (4) carrying out ring closing reaction on the brominated product in the step (3) under the action of acid to obtain the 3-hydroxy cephalosporin. The preparation process solves the problem of amplification effect of bromination reaction, and improves the yield and quality of the product.

The present invention discloses a steroidal derivative containing a pyrazole-thiazolinone heterocycle and its preparation method and application. The steroidal derivative containing a pyrazole-thiazolinone heterocycle of the present invention has a strong inhibitory effect on nitric oxide (NO) produced by lipopolysaccharide (LPS)-induced RAW 264.7 mouse peritoneal macrophages and BV2 mouse microglial neurons, especially the anti-inflammatory activity of compound 5 prepared by the preparation method is better than dexamethasone, and the toxicity is less than dexamethasone, and the effect of different substituents on the inhibitory activity can be combined to expand the in-depth application of steroidal derivatives of pyrazole-thiazolinone heterocycles in fighting inflammation. The compound of the present invention is simple to prepare, and the raw materials are easy to obtain. More importantly, it has good anti-inflammatory activity and lower cytotoxicity, which is of great significance in the preparation of drugs for preventing and treating inflammation / neuroinflammation or autoimmune-related diseases.

The present invention discloses a method for dual-mode detection of glufosinate residues in coffee by colorimetry and chemiluminescence, belonging to the technical field of chemical analysis and detection. In this method, the Schiff base formed by 4-aminoantipyrine and glutaraldehyde is used as a complexing agent for Cu 2+ . Then, microwave digestion is used to prepare copper-doped carbon dots Cu-CDs nanozyme. The Cu-CDs nanozyme has excellent peroxidase-like activity, oxidizes colorless 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) into blue-green oxidized ABTS, and is used as a catalyst for chemiluminescence, which can increase the chemiluminescence intensity of the reaction between N-(4-aminobutyl)-N-ethylisoluminol and H2O2 by nearly 100 times. Based on the inhibitory effect of glufosinate on the POD-like activity of Cu-CDs, a sensitive and rapid dual-channel GM detection technology by colorimetry and chemiluminescence has been developed. The method of the present invention has potential application value in coffee safety monitoring.

The invention belongs to the field of polymer biological materials, and particularly relates to a thiazoline-pyrimidone structure-containing polymer which can be used as an effective component of sunscreen cream. The preparation method comprises the following steps: (1) in an anhydrous organic solvent, mixing a thiazoline-pyrimidone monomer and polyethylene glycol methacrylate for reaction to obtain a component A; and (2) in an inert atmosphere, mixing a free radical initiator with the component A, reacting to obtain a component B, and then separating a copolymer containing a thiazoline-pyrimidone structure from the component B to serve as the sun-screening agent for ultraviolet protection of mice, and the structure of the copolymer is as shown in a formula I. The invention further discloses a preparation method of the sun-screening agent for ultraviolet protection of mice. The polymer provided by the invention has a good effect on biological ultraviolet protection.

The present invention discloses a steroidal dihydropyrazole thiazoline derivative, 3β-hydroxy-pregnane-5-en-17β-yl-5'-(substituted phenyl)-1'-(4''-phenyl-[1'',3'']-thiazol-2''-yl)-4',5'-dihydropyrazole-3'-yl. The present invention also discloses the use of the steroidal dihydropyrazole thiazoline derivative. The steroidal dihydropyrazole thiazoline derivative of the present invention has a strong inhibitory effect on nitric oxide (NO) production in RAW 264.7 mouse peritoneal macrophages induced by lipopolysaccharide (LPS), especially compound 4 in the prepared steroidal dihydropyrazole thiazoline derivative has an IC of 0.05. 50 The value is better than that of the positive control methylprednisolone, and the toxicity to cells is low. The steroidal derivative containing a dihydropyrazole thiazoline heterocycle provided by the present invention is a new structural compound, which shows higher activity than existing first-line anti-inflammatory drugs.

This invention discloses a molecularly imprinted paper-based microfluidic colorimetric sensor for detecting histamine, its preparation, and its application. The colorimetric sensor (MIP@MIL) is polymerized from a metal-organic framework (MIL-101) using surface molecular imprinting and dual-monomer imprinting techniques. MIP@MIL exhibits a histamine detection limit of 0.77 μM and a detection time of 12.5 min, demonstrating good selectivity. The mechanism involves histamine blocking the imprinted pores of MIP@MIL and acting on MIL-101, thereby weakening the catalytic oxidation process of the chromogenic agent 2,2'-azido-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS). Furthermore, histamine increases the repulsive force of MIP@MIL against ABTS, thus enabling colorimetric detection of histamine. To further improve practical applicability, MIP@MIL was loaded onto qualitative filter paper and further modified onto microfluidic paper-based chips (μPADs). Using a smartphone, rapid and accurate visual detection of histamine in food was achieved, demonstrating its potential for food freshness detection.

The invention discloses a method for synthesizing an amide compound by utilizing visible light / benzothiazoline derivative synergistic induction triazine ester, which comprises the following steps: by taking the triazine ester and a nitrobenzene compound as reaction substrates and the benzothiazoline derivative as a light reducing agent, carrying out a reaction on the triazine ester and the nitrobenzene compound in the presence of organic alkali, and carrying out a reaction to obtain the amide compound. Triazine ester and a benzothiazoline derivative form a donor-acceptor compound through intermolecular interaction, a single electron transfer process is triggered through visible light excitation, and then acyl radicals are generated; a nitrobenzene compound can be changed into free radical nitro aromatic hydrocarbon under the reaction system, an acyl free radical addition process is carried out, nitrosobenzene and N-(benzoyloxy)-N-phenylaniline are sequentially changed, and finally the target product amide compound is synthesized. The method has the advantages of being green, safe and easy to operate, the reaction condition is mild and efficient, the reaction time is short, the atom economy is high, the target product yield is high, the substrate applicability is wide, and the wide application prospect is achieved.

The application discloses a preparation method and application of sodium thiazolinyl dithiopropane sulfonate, and comprises the following steps: adding 1,3-propane sulfolane solution and an oxidizing agent into a mixed solution containing 2-mercaptothiazoline, sodium hydrosulfide and a solvent at 5-25 DEG C, and then reacting at 20-35 DEG C, and then recrystallizing to obtain sodium thiazolinyl dithiopropane sulfonate; the one-pot method is used to synthesize sodium thiazolinyl dithiopropane sulfonate by using 2-mercaptothiazoline, sodium hydrosulfide and 1,3-propane sulfolane as raw materials, a series of problems such as low yield and low effective content caused by multi-step reaction and repeated purification are avoided, the yield (more than 80%) and the purity (more than 95%) of the product are greatly improved, and the product is beneficial to large-scale production.

The invention discloses a long-acting antibacterial adsorption filler and a preparation method thereof. The preparation method comprises the following steps: S1, preparing composite activated aluminum oxide; s2, preparation of aminated composite aluminum oxide; s3, preparation of organic composite aluminum oxide; and S4, preparing the long-acting antibacterial adsorption filler. According to the long-acting antibacterial adsorption filler, cerium and bismuth composite oxide is loaded on an activated aluminum oxide substrate, then maleic anhydride, 2, 3-epoxypropyltrimethylammonium chloride and 2-mercaptothiazoline are sequentially introduced through bridging of a silane coupling agent, and the finally prepared filler integrates multiple functions of physical adsorption, chemical adsorption, contact sterilization, slow-release sterilization and the like; according to the method, the technical problem that secondary pollution is easily caused due to the fact that a traditional adsorbent is single in function and cannot sterilize is effectively solved, and comprehensive and long-term purification of indoor air pollutants is achieved.