547 results about "Phenothiazine" patented technology

The invention provides formulations and structural modifications for phenothiazine compounds which result in altered biodistributions, thereby reducing the occurrence of adverse reactions associated with this class of drug.

Methods of treating headache with antipsychotics are provided. A kit for treating headache is also provided, comprising an antipsychotic and a device for rapid delivery of the antipsychotic.

The invention relates to a lubricating oil composition having improved antioxidant properties, and which contains a molybdenum compound and an alkylated phenothiazine. Further, it may also include a secondary diarylamine, preferably an alkylated diphenylamine. This combination of additives provides improved oxidation control and friction modifier performance to the lubricating oil. The composition is particularly suited for use as a crankcase lubricant, or a transmission lubricant, including low levels and zero levels of phosphorus.

The invention discloses an organic luminescent material based on a phenanthreneopyrazine derivative and an electroluminescent device thereof, belonging to the technical field of organic electroluminescence. The structural general formula of the luminescent material is shown in the specification, wherein R refers to triphenylamine group or derivatives thereof, diphenylamine group or derivatives thereof, carbazolyl or derivatives thereof, N-phenylcarbazyl or derivatives thereof, phenothiazine or derivatives thereof, or phenoxazine or derivatives thereof. The phenanthreneopyrazine derivative can serve as a luminescent material and is used for preparing a high-performance electroluminescent device. The compound disclosed by the invention has the advantages that the preparation process is simple, and the prepared electroluminescent device is high in efficiency and long in service life, and the like. The device can be applied to the fields of panel display, illumination and light sources.

The present invention relates to a phenothiazinium compound of Formula (I): wherein: A and B each independently is in which R' and R'' each independently is a linear, branched or cyclic hydrocarbon group, or R' and R'' together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7-membered ring; and where X<p-> is a counteranion and P is 1, 2 or 3; except for the compounds in which A and B are both either -N(CH3)2 or -N(CH2CH3)2 for use in a treatment that requires removal, deactivation or killing of unwanted tissues or cells. The invention also relates to compositions comprising the compounds of Formula I, to selected compounds of Formula I, use of the compounds of Formula I as medicaments and as a PDT agent or a photodiagnostic agent, a conjugate or composite formed between a compound of Formula I and a polymer; and to a method for sterilising fluids in which the fluid is passed over the conjugate or composite whilst it is illuminated. The compounds are biologically active photosensitisers which are strongly photocytotoxic and have application in the areas of photodynamic therapy (PDT), as well as for the diagnosis and detection of medical conditions and related uses in photochemical internalisation, in the production of cancer vaccines, in the treatment and prevention of microbial infections and in photodisinfection or photosterilisation.

Disclosed herein are phenazine-3-one and phenothiazine-3-one derivative compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging.

Methods of treating headache with antipsychotics are provided. A kit for treating headache is also provided, comprising an antipsychotic and a device for rapid delivery of the antipsychotic.

This invention relates to lubricating oil additives, and to lubricating oil compositions, their method of preparation, and use. More specifically, this invention relates to several novel lubricating oil additives and compositions which contain a tungsten compound and an antioxidant, namely aminic antioxidants such as a secondary diarylamine or an alkylated phenothiazine. The use of the tungsten compound with the secondary diarylamine and / or the alkylated phenothiazine provides improved oxidation and deposit control to lubricating oil compositions. The lubricating oil compositions of this invention are particularly useful as crankcase and transmission lubricants, gear oils and other high performance lubricant applications.

The invention belongs to the technical field of textile fabric finishing agents, and relates to a method for preparing an intermediate fluorine-containing acrylate monomer of a water-proof and oil-proof organic fluorine fabric finishing agent. The method is characterized by comprising the following steps of: (1) in the presence of a reducing agent, preparing polyfluoroalcohol by using a perfluoroalkylacyl compound as a raw material; and (2) slowly dripping (methyl) acryloyl chloride to prepare fluorine-containing acrylate in the presence of a catalyst by using the polyfluoroalcohol prepared in the step (1) and using phenothiazine as a polymerization inhibitor. The number of long-chain perfluoroalkyl carbon atoms in the prepared fluorine-containing acrylate is less than 8, and the fluorine-containing acrylate can be degraded and has no biological accumulation. The fluorine-containing acrylate has no hidden dangers of long-chain perfluoroalkyl to destroy the environment and harm human health. Fluorine-containing acrylate copolymer emulsion prepared by using the prepared fluorine-containing acrylate monomer is used as a water-proof and oil-proof finishing agent for textiles, and the finished textiles have excellent water-proof and oil-proof performance.

The invention belongs to the technical field of fabric finishing agents, and particularly relates to a method for preparing a fluorine-containing acrylate copolymer textile finishing agent, which is characterized by sequentially comprising the following steps of: 1, preparing fluorine-containing acrylate: slowly dripping a perfluor alkyl acyl compound by using (methyl) acrylic hydroxy alkyl ester as a raw material and phenothiazine as a polymerization inhibitor in the presence of a catalyst; and 2, preparing a fluorine-containing acrylate copolymer: pre-emulsifying polymer monomer by adding an emulsifying agent, and dripping an initiator into pre-emulsion for polymerizing the emulsion under the protection of nitrogen. The fluorine-containing acrylate copolymer emulsion is used as a waterproof oil resistant finishing agent for fabrics; and the finished fabrics present excellent waterproof oil resistance property. Carbon atoms of long-chain perfluor alkyl in the fluorine-containing acrylate monomer prepared by the method are not less than 8, and hidden dangers of damaging the environment and harming human health by the long-chain perfluor alkyl waterproof oil resistant fabric finishing agent do not exist.

Disclosed herein are phenazine-3-one and phenothiazine-3-one derivative compounds and methods of using such compounds for treating or suppressing oxidative stress disorders, including mitochondrial disorders, impaired energy processing disorders, neurodegenerative diseases and diseases of aging.

A process for producing (meth)acrylic acid while preventing a polymerization of (meth)acrylic acid using a polymerization inhibitor solution, comprising the steps of: obtaining a (meth)acrylic solution containing formaldehyde from any step of the process for producing (meth)acrylic acid to use as a solvent of the polymerization inhibitor solution, and adding phenothiazine or derivatives thereof and / or hydroquinone or derivatives thereof to the (meth)acrylic solution containing formaldehyde to obtain polymerization inhibitor solution so that the polymerization inhibitor solution contains 0.1 mass % to 3 mass % of phenothiazine or derivatives thereof and / or 0.1 mass % to 10 mass % of hydroquinone or derivatives thereof, wherein the polymerization inhibitor solution contains 10 ppm to 5000 ppm (based on mass) of formaldehyde. The polymerization inhibitor solution used in the present invention is stable, generates little precipitate and is prepared using a low purity (meth)acrylic acid solution from the process for producing (meth)acrylic acid.

The invention relates to compounds of general formula (I): wherein: each of R1 and R9 is independently selected from: —H, C1-4alkyl, C2-4alkenyl, and halogenated C1-4alkyl; each of R3NA and R3NB is independently selected from: —H, C1-4alkyl, C2-4alkenyl, and halogenated C1-4alkyl; each of R7NA and R7NB is independently selected from: —H, C1-4alkyl, C2-4alkenyl, and halogenated C1-4alkyl; and wherein: each of RA and RB is independently selected from: C1-4alkyl, halogenated C1-4alkyl, and C6-10aryl; or RA and RB are linked to form a group selected from: C1-6 alkylene and C6-10 arylene; and pharmaceutically acceptable salts thereof, which are useful in the treatment of, for example, Alzheimer's disease. In other aspects the invention also relates to novel formulations of 3,7-diamino-10H-phenothiazinium salts.

This invention relates to lubricating oil additives, and to lubricating oil compositions, their method of preparation, and use. More specifically, this invention relates to several novel lubricating oil additives and compositions which contain a tungsten compound and an antioxidant, namely aminic antioxidants such as a secondary diarylamine or an alkylated phenothiazine. The use of the tungsten compound with the secondary diarylamine and / or the alkylated phenothiazine provides improved oxidation and deposit control to lubricating oil compositions. The lubricating oil compositions of this invention are particularly useful as crankcase and transmission lubricants, gear oils and other high performance lubricant applications.

The invention relates to the technical field of a chemistry stabilizer, in particular to an environmental-friendly calcium-zinc stabilizer for a PVC (Polyvinyl Chloride) rolling film and a preparation method thereof. The environmental-friendly calcium-zinc stabilizer for the PVC (Polyvinyl Chloride) rolling film comprises the following raw materials in percentage by weight: 10-30% of main calcium salt stabilizer, 10-30% of main zinc salt stabilizer, 30-50% of hydrotalcite, 10-20% of lubricating agent, 5-15% of phenothiazine heterocyclic compound, 1-5% of oxidation inhibitor, 1-5% of ultraviolet light absorber and 1-5% of auxiliary stabilizer. The preparation method of the environmental-friendly calcium-zinc stabilizer for the PVC (Polyvinyl Chloride) rolling film comprises the following steps of: putting the raw materials in a high-speed blender in three stages and totally stirring for 30 min in the temperature of 55-56 DEG C, wherein the rotating speed of the blender is 1000-1500r / min. The environmental-friendly calcium-zinc stabilizer for the PVC (Polyvinyl Chloride) rolling film, which is prepared by the invention, has good thermal resistant property and weather resistance.

The invention discloses a thermal activation delayed fluorescence material based on a dibenzophenazine derivative as well as a preparation method and application of the thermal activation delayed fluorescence material, and belongs to the technical field of organic photoelectric materials and devices. The structural formula of the material is shown as a formula (I), in the formula (I), R1 is phenoxazinyl, phenothiazinyl or dimethyl acridinyl, R1' is phenoxazinyl, phenothiazinyl or dimethyl acridinyl, R1 '' is phenoxazinyl, phenothiazinyl or dimethyl acridinyl, and R2 is H, phenoxazinyl, phenothiazinyl or dimethyl acridinyl. The material provided by the invention has the advantages that the electron acceptor and the electron donor unit show a highly distorted rigid structure, 100% theoretical internal quantum efficiency can be realized, the fluorescence quantum yield is high, a guarantee is provided for a high-efficiency long-waveband OLED device, and the like. And a polysubstitution mode is adopted, so that red shift of molecular emission wavelength is facilitated, long-waveband luminescence is realized, and a guarantee is provided for an efficient long-waveband OLED device.

Inhibition of RNA function, and treatment or control of diseases or conditions, e.g. infectious diseases such as viruses and viral infections (including HIV) and microbial infections, by the contacting of the RNA with a compound having a central or core structure comprising three fused rings containing from 12 to 15 ring atoms, the central ring including at least one heteroatom selected from nitrogen, oxygen and sulfur, the atoms of the three-ring core structure being optionally substituted with substituents such as halogens, cyano, and / or various substituted or unsubstituted aliphatic and / or heteroaliphatic moieties, or contacting the RNA with yohimbine, usnic acid or N-{4-[2,5-Dioxo-1-(4-trifluoromethoxy-phenyl)-pyrrolidin-3-yl]-phenyl}-2,2,2-trifluoro-acetamide. Preferred compounds are various phenothiazines, including both known and novel compounds.

The invention belongs to the technical field of organic electroluminescence material, in particular to a series of phosphorescent dye parent materials with a tetrahedral structure, and the application of the materials in an electroluminescent device. The phosphorescent dye parent materials can be used for a panel display device, a light-emitting diode (LED) and an electronic imaging device. The phosphorescent dye parent material has excellent electronic and hole transmission properties, can be independently used as a luminous layer and a current carrier transmission layer, and can be used as matrix and doped with other fluorescent or phosphorescent dyes. The compound has stronger fluorescent property in a state of solution or solid, can be used for forming an even film, and has better optical stability and thermal stability. R1, R2, R3 and R4 are respectively connected with phenyl group by a single bond, and are respectively selected from one of hydrogen, alkyl group, alkoxy, nitryl, hydroxyl, cyano-group, benzene cyano-group, amino, sulfydryl, halogen, diphenyl phosphoryl, furan, thiophene, pyrrole, pyridina, diazine, triazine, pyran, quinoline, benzpyrole, carbazole, aniline or phenothiazine, and X is C or Si.

The invention discloses a phenothiazine-containing polymerization metal complex as well as a preparation method and an application thereof. The phenothiazine-containing polymerization metal complex is a novel dyestuff with a phenothiazine-thiophene side chain type D-pi-A structure. Compared with a conventional precious metal dyestuff, the novel dyestuff has the advantages of low cost, simple preparation, relatively high yield and good thermal stability and can be applied to dye-sensitized solar cells.

The present invention is directed to methods for the treatment or prophylaxis of a tauopathy comprising administering to a patient in need thereof a medicament comprising a phenothiazine.

A holographic recording medium includes a recording layer. The recording layer includes a framework being expressed with the following general formula (1),In the above formula (1), Ar represents a substituted or unsubstituted group selected from benzothiophene group, naphthothiophene group, dibenzothiophene group, thienothiophene group, dithienobenzene group, benzothiazole group, naphthothiazole group, benzoisothiazole group, naphthoisothiazole group, phenothiazine group, phenoxathiin group, dithianaphthalene group, thianthrene group, thioxanthene group, and bithiophene group. In addition, n is an integer from 1 to 4.

The present invention relates to one kind of high efficiency composite polymerization inhibitor for refining styrene. The composite polymerization inhibitor is re-compounded with aromatic amine compound, nitrogen-oxygen free radical or phenothiazine, and nitrophenol compound in certain proportion, and through dissolving in organic solvent. The composite polymerization inhibitor has the synergistic effect of the polymerization retarder and polymerization inhibitor, obviously polymerization inhibiting effect higher than single polymerization inhibitor, lowered toxicity and raised solubility, and can meet the requirement for styrene rectifier to run stably for long term.

A scorch inhibitor composition for polyurethane foams is composed of(a) one or more derivatized phenolic compounds in an amount of about 60-80% by weight;(b) one or more aromatic amines in the form of a liquid in an amount of about 15-35% by weight;(c) an alkyl-substituted hydroquinone in an amount of about 4-8% by weight, and(d) phenothiazine at 0 to about 1.0% by weight.

The invention belongs to the technical field of photoelectric material, and concretely relates to a benzene-substituted phenothiazine unit-based luminescent material, an intermediate thereof and an organic photoelectric device made by the luminescent material. The luminescent material takes phenothiazine as an initial reaction raw material, the intermediate is prepared through an Ullmann reaction, and a target compound is obtained through the Ullmann reaction or a Suzuki reaction. The material has the advantages of single structure and definite molecular weight; has high decomposition temperature and low sublimation temperature, and the luminescent material with high purity cab can be easily obtained through sublimation. The material has good luminescence performance as a luminescent layer of the organic photoelectric device and can be used for an organic micromolecule light emitting diode.

The invention relates to (among other things) oligomer-phenothiazine conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over un-conjugated phenothiazine compounds.

The invention provides an organic dye for a dye sensitized solar cell and a preparation method of the organic dye, belonging to the technical field of organic high polymer materials and relating to a dye sensitized solar cell technology. In the provided organic dye, phenothiazine-triphenylamine is used as a cascading electron donor, and the organic dye provided by the invention belongs to a D-D-pi-A structured molecule and is novel organic dye containing a phenothiazine-triphenylamine cascading electron donating group. The organic dye provided by the invention is applied to the dye sensitizedsolar cell, and higher photoelectric conversion efficiency is obtained. The preparation method has the characteristics of low cost and simple, controllable preparation process and environmental friendliness. The novel organic dye molecule belongs to a pure organic compound, expensive raw material metal ruthenium does not need to be used, the novel organic dye is easy to synthesize, and has low cost and potential application prospect in the aspect of substituting noble metal organic dyes.

This invention relates to lubricating oil additives, and to lubricating oil compositions, their method of preparation, and use. More specifically, this invention relates to several novel lubricating oil additives and compositions which contain a tungsten compound and an antioxidant, namely aminic antioxidants such as a secondary diarylamine or an alkylated phenothiazine. The use of the tungsten compound with the secondary diarylamine and / or the alkylated phenothiazine provides improved oxidation and deposit control to lubricating oil compositions. The lubricating oil compositions of this invention are particularly useful as crankcase and transmission lubricants, gear oils and other high performance lubricant applications.

Methods of treating headache with antipsychotics are provided. A kit for treating headache is also provided, comprising an antipsychotic and a device for rapid delivery of the antipsychotic.