109 results about "Phenothiazine" patented technology

The invention provides anthracene methyl phenothiazine for a photosensitive resin composition, and relates to the field of photopolymerization. The invention further comprises a photosensitive resin composition containing the anthracene methyl phenothiazine, a photosensitive dry film containing the anthracene methyl phenothiazine and application of the photosensitive resin composition and the photosensitive dry film. The anthracene methyl phenothiazine disclosed by the invention has photosensitivity, can be used as a photosensitizer in the photosensitive resin composition, can improve the adhesive force of the photosensitive resin composition on various metal surfaces, and has the characteristic of low migration; the method can be widely applied to the photo-curing fields of dry films, paints, coatings, printing ink, forming materials and the like.

The invention belongs to the field of perovskite solar cells, and particularly relates to application of a bulk phase and interface synergistic passivator in a perovskite solar cell. The invention provides a bulk phase / interface synergistic passivation innovative strategy, molecules with a tricyclic sulfur-nitrogen heterocyclic ring structure are introduced as a synergistic passivator, and defect global repair of each functional layer of a device is realized. The molecular design of the structural derivative taking phenothiazine as the core has the following advantages: skeleton characteristics: a conjugated tricyclic system forms an electron transport network through pi-pi stacking, endows molecules with excellent electron delocalization ability, and effectively regulates and controls carrier kinetics; the thioether group is used for dynamically repairing an ion migration channel through oxidation-reduction activity and inhibiting formation of deep-energy-level defects; and the secondary amine group is used as a hydrogen bond donor for anchoring uncoordinated halide ions and synchronously passivating surface and grain boundary defects.

The invention relates to a 5, 9-di-tert-butyl naphtho-indolizine phenothiazine compound as well as a preparation method and medical application thereof. The compound is efficiently synthesized through Ullmann coupling and palladium-catalyzed intramolecular arylation reaction. In-vitro anti-tumor activity research shows that the compound has remarkable selective inhibitory activity on various human tumor cell lines, and particularly, the inhibitory effect on non-small cell lung cancer A549 cells (IC50 = 0.21 mu M) is improved by two orders of magnitude compared with that of cis-platinum; iC50 (half maximal inhibitory concentration) of other cell lines are as follows: 1.26 mu M of prostate cancer PC-3 cells, 6.78 mu M of liver cancer HepG2 cells, 7.99 mu M of cervical cancer Hela cells and 25.46 mu M of breast cancer MCF-7 cells. Preliminary toxicity experiments prove that the compound has the characteristic of low cytotoxicity. The compound can be used as a novel high-efficiency low-toxicity anti-tumor lead compound, and provides an important structural basis for the development of anti-cancer drugs.

The invention relates to the technical field of solar cells, in particular to a self-assembled monomolecular hole transport material, a preparation method and application thereof, a perovskite solar cell, a preparation method thereof and a photovoltaic module. The self-assembled monomolecular hole transport material provided by the invention has a structure as shown in a formula I. In the formula I, A1, A2 and A3 are respectively and independently anchor groups or hydrogen atoms; the anchoring groups are independently selected from phosphate groups respectively; g is selected from a substituted or unsubstituted carbazolyl group, a substituted or unsubstituted acridinyl group, a substituted or unsubstituted phenothiazinyl group, and a substituted or unsubstituted phenoxazinyl group. The self-assembled monomolecular hole transport material provided by the invention has stronger anchoring binding capacity, conjugation in molecules is enhanced through the aromatic connection unit, and transport of carriers is facilitated; polyphosphonic acid anchoring in the self-assembled monomolecular hole transport material provided by the invention can enhance adsorption and uniformity of molecules, and a formed hole transport interface has better charge transport and defect passivation effects.

The application discloses a phenothiazine self-assembled organic small-molecule hole transport material and application thereof, wherein the structural general formula of the phenothiazine self-assembled organic small-molecule hole transport material is as follows: wherein R is n is 1-5. The disclosed phenothiazine self-assembled organic small-molecule hole transport material is based on a self-assembled monolayer design strategy, carboxylic acid anchoring groups and different bridging units are introduced into the phenothiazine molecular structure, the adjustment of the hole transport material molecular energy level and the improvement of the hole transport layer interface contact are realized. When the material is applied to a perovskite solar cell device as a non-doped hole transport layer, it shows good photoelectric conversion efficiency. Especially important is that the synthesis process is simple, the raw material source is wide and the price is low, so that the material is more competitive in practical application, and is expected to bring a new breakthrough to the development of perovskite solar cells.

This application relates to the field of tail gas absorption technology, specifically disclosing a tail gas absorption device for phenothiazine production. The pretreatment mechanism in this application can induce sublimation of phenothiazine microcrystals in the tail gas through multiple stages, allowing the microcrystals to grow sufficiently to a collectable size before entering the collection zone. Then, a multi-stage blade collection mechanism progressively adheres and collects the grown microcrystals, achieving efficient recovery of the phenothiazine microcrystals. Simultaneously, an absorption tower is set up to absorb hydrogen sulfide from the collected tail gas with alkaline solution, and an activated carbon adsorption tower is set up to deeply purify residual hydrogen sulfide and volatile organic compounds. This forms a complete treatment chain with graded treatment and each stage performing its specific function, effectively solving the problem of blockage caused by microcrystals directly entering the absorption tower in existing technologies, while also achieving the recycling of high-value products.

The application relates to the technical field of organic fluorescent probes, and particularly discloses a lipid droplet and hypochlorous acid sequence response type fluorescent probe, a structural formula of which is as shown in the figure; wherein R is a cyano group, a benzothiazole group, a benzimidazole group, an amido group, an ethoxycarbonyl group or an acetyl group. The precise imaging lipid droplet and hypochlorous acid sequence response fluorescent probe of the application takes a phenothiazine-coumarin dye support as a matrix, utilizes a double trifluoromethyl benzyl group as a lipid droplet targeting group, adjusts the dye emission wavelength by introducing different electron-withdrawing groups, synthesizes a series of probes, and realizes high-targeting sequence imaging of lipid droplets and hypochlorous acid in atherosclerotic plaques.

This invention relates to the field of organic synthesis technology, specifically to a highly efficient and stable Grignard preparation and its green preparation method. By weight, it comprises 8-18 parts of a magnesium source, 40-92 parts of a halogenated hydrocarbon, 150-200 parts of a green solvent, 15-20 parts of ethylene glycol dimethyl ether, and 2.3-3.2 parts of a synergistic stabilizer. The green solvent is 2-methyltetrahydrofuran, or a composite solvent with a weight ratio of 2-methyltetrahydrofuran:methyl tert-butyl ether of 150-160:40-50. The synergistic stabilizer is composed of 1.5-2.0 parts of N,N,N',N'-tetramethylethylenediamine and 0.8-1.2 parts of butylated hydroxytoluene, or composed of 1.5-2.0 parts of N,N,N',N'-tetramethylethylenediamine and 1.0 part of phenothiazine. This invention uses a green solvent system to replace traditional toxic and harmful solvents, and combines it with a solvent recovery process to achieve solvent recycling, which greatly reduces waste emissions and makes the production process safer and more environmentally friendly, in line with the development direction of green chemical industry.

The application belongs to the field of detection reagents, and particularly relates to a single-component luminol chemiluminescence substrate liquid and a preparation method thereof. The single-component luminol chemiluminescence substrate liquid comprises the following components: sodium acetate, sodium perborate, N-N dimethylacetamide, beta-cyclodextrin, luminol, 4-morpholinopyridine, p-acetylaminophenol, 4-hydroxyphenylacetic acid, phenothiazine-10-yl-propyl sulfonic acid sodium salt and isothiazolinone. The purpose of the application is to solve the technical defects that the luminol chemiluminescence substrate liquid in the prior art must be packaged in two components due to the instability of the luminous agent and the oxidizing agent in the liquid phase, leading to inconvenient use and easy introduction of operation errors, so as to provide a single-component luminol chemiluminescence substrate liquid and a preparation method thereof, which have high storage stability, high luminous performance and convenient use.

The invention discloses a phosphabicyclo [3, 2, 0] organic phosphorus compound as well as a preparation method and application thereof. Diallyl-containing tertiary phosphine oxide and phosphine sulfur compounds are used as raw materials, 10-phenyl phenothiazine is used as a photocatalyst, the photocatalyst is excited under a light source of 390 nm to activate double bonds, high-stereoselectivity [2 + 2] cycloaddition reaction is realized, the phosphorus heterocyclic bicyclo [3, 2, 0] organophosphorus compound containing two quaternary carbon centers is synthesized, diastereoisomers can be separated, and the yield is high. A single diastereoisomer product is as high as 97%, and excellent diastereoselectivity is achieved. The invention provides a green reaction mode for photocatalytic synthesis of the phosphabicyclo [3, 2, 0] organophosphorus compound, the conditions are mild, and the substrate universality is good. The obtained phosphabicyclo [3, 2, 0] organophosphorus compound is applied to a primary alcohol chlorination reaction as a catalyst, shows high reaction activity, and has more excellent catalytic activity compared with a reported catalytic system.

The invention belongs to the technical field of organic synthesis and medicinal chemistry, and particularly relates to a synthesis method of a novel polycyclic aromatic hydrocarbon derivate 2, 6-di-tert-butyl pyrene and indolizine phenothiazine compound and application of the compound in the aspect of anti-cancer drugs. The synthesis process is simple and convenient, conditions are mild, and the yield is ideal. Pharmacodynamic evaluation shows that the compound shows strong inhibitory activity on various human cancer cell lines, and the IC50 values are respectively cervical cancer Hela cells (0.17 mu M), lung cancer A549 cells (0.3 mu M), prostatic cancer PC-3 cells (0.42 mu M) and liver cancer HepG2 cells (10.79 mu M), which are respectively reduced by 109 times, 173 times, 35 times and 1.8 times compared with positive control drug cis-platinum. In addition to efficiently inhibiting cancer cells, the compound has low toxicity to normal cells, meets the basic requirements of excellent anti-cancer drugs, and shows important application value and potential in the field of research and development of novel anti-cancer drugs.

The invention belongs to the technical field of fluorescent probes, and particularly relates to a single-molecule fluorescent probe based on a phenothiazine structure as well as a preparation method and application of the single-molecule fluorescent probe. The preparation method comprises the following steps: firstly introducing an alkyl chain to a nitrogen atom of a raw material to obtain the phenothiazine structure-based single-molecule fluorescent probe, then carrying out regioselective formylation on the raw material to obtain the phenothiazine structure-based single-molecule fluorescent probe, then treating the raw material by adopting aluminum trichloride to realize O-demethylation, and finally carrying out intramolecular cyclization reaction on the raw material and 1H-benzimidazole-2-acetonitrile to obtain the phenothiazine structure-based single-molecule fluorescent probe. The single-molecule fluorescent probe based on the phenothiazine structure prepared by the invention is compatible with orthogonal chemical reaction activity and maintains controllable electron transfer, so that different chemical events are converted into specific optical signals, and selective and mechanism specific fluorescent response to phosgene, copper ions and hypochlorite is realized.

The present invention relates to sulfoxylated phenothiazine for use as a medicament. The present invention also relates to sulfoxylated phenothiazine for use in the treatment of painful sensations induced by neuropathy. The present invention also relates to a pharmaceutical composition comprising at least one sulfoxylated phenothiazine.

The application belongs to the technical field of organic synthesis, and provides a star structure carbazole derivative, a preparation method thereof and a carbazole conductive polymer. The application obtains an intermediate by mixing 10-phenyl-10H-phenothiazine, N-bromosuccinimide and a first organic solvent for reaction; obtains the star structure carbazole derivative by mixing the intermediate, 9H-carbazole-2-boronic acid pinacol ester, tetrakis(triphenylphosphine)palladium, an accelerator and a second organic solvent for reaction; and obtains the carbazole conductive polymer by mixing the star structure carbazole derivative and an electrolyte solution for cyclic voltammetry electrochemical polymerization. The method is simple, has few by-products, and the star structure carbazole derivative obtained by the method is a non-coplanar star structure, which is beneficial to the embedding and discharging of electrolyte ions, so that the carbazole conductive polymer has excellent electrochemical performance and energy storage properties, and the conductive polymer also has excellent electrochromic performance.

The invention belongs to the technical field of fluorescence sensing, and particularly relates to a zinc-based coordination polymer based on a heterocyclic ligand and a preparation method and application thereof. The method comprises the following steps: dissolving 3, 7-dibromo-10H-phenothiazine, pyridine-4-boric acid and K2CO3 in a mixed solution of DMF (Dimethyl Formamide) and H2O, uniformly stirring, then adding tetrakis (triphenylphosphine) palladium, carrying out a heating reflux reaction under protective gas, removing a solvent after the reaction is finished, separating impurities, and purifying to obtain 3, 7-bis (4-pyridyl) phenothiazine; the preparation method comprises the following steps: preparing a heterocyclic ligand, dissolving the heterocyclic ligand and zinc nitrate hexahydrate in a mixed solution of DMF and H2O, uniformly stirring, heating to react, and washing and drying after the reaction is finished to obtain the zinc-based coordination polymer based on the heterocyclic ligand. According to the present invention, by using the butterfly conformation and electron donating effect of the ligand molecule 3, 7-bis (4-pyridyl) phenothiazine and the coordination binding capacity synergistic effect of pyridine, the ligand molecule 3, 7-bis (4-pyridyl) phenothiazine is coordinated with zinc ions to construct the novel material with excellent luminescence property;

The invention discloses a quick response type near-infrared fluorescent probe for detecting Hg < 2 + >, a preparation method of the quick response type near-infrared fluorescent probe and application of the quick response type near-infrared fluorescent probe in actual water samples and biological imaging. The molecular formula of the fluorescent probe is C32H28N2O2S2. On the basis of a strategy of introducing phenothiazine heterocycle to expand xanthene pi conjugation, a large Stokes shift near infrared fluorescent probe for specifically recognizing Hg < 2 + > is constructed. An optical experiment shows that the emission wavelength of the probe for detecting Hg < 2 + > is 780nm, the Stokes shift reaches 166nm, and the probe has the advantages of high sensitivity (the detection limit is 13.4 nM), specificity, quick response (within 1s) and the like when being used for identifying Hg < 2 + >. Due to the excellent photophysical property, the fluorescent probe not only can be used for quantitatively detecting Hg < 2 + > in an environmental water sample, but also can be successfully applied to fluorescence imaging detection of Hg < 2 + > in cells and living bodies.

The present invention provides a catalyst for synthesizing a cyclic carbonate and a preparation method and use thereof. A diamine compound X, a salicylaldehyde-containing compound and a metal source M are subjected to reaction, and then added with a phenothiazine compound Y for continuous reaction to obtain a phenothiazine metal Schiff base catalyst. The formation of phenothiazine free radicals by phenothiazine compounds with a central metal can protect the central metal in the course of reaction and inhibit inactivation caused by the self-polymerization of the central meta, thus improving the activity and stability of a catalyst. Phenothiazine compounds can be present as a polymerization inhibitor to inhibit the generation of by-products such as polycarbonates and polyethylene glycol and enhance the selectivity of the catalyst during the reaction. The phenothiazine compounds are alkaline and can adsorb and activate carbon dioxide during reaction, which helps to improve the reaction efficiency. The phenothiazine metal Schiff base catalyst prepared in the present invention has high activity, strong stability and good selectivity and thus, can achieve the efficient catalyzed synthesis of cyclic carbonates under mild conditions.

A method for preparing diphenylamine and phenothiazine from aniline includes the steps of reacting an aniline raw material; carrying out gas-liquid separation on an obtained reaction mixture containing diphenylamine, and obtaining a first liquid product and a first gas product, separating the first liquid product, and obtaining an aniline reclaimed material and a diphenylamine product; reacting part of the obtained diphenylamine product; carrying out gas-liquid separation on an obtained reaction mixture containing phenothiazine, obtaining a second liquid product and a second gas product, and separating a phenothiazine product from the second liquid product. Coupling a diphenylamine synthesis process and a phenothiazine synthesis process reduces the energy consumption of the coupled processes. In addition, the output of the two products and purities thereof can be flexibly adjusted to optimize the product structure.

This invention belongs to the field of organic solar cells, specifically disclosing the application of an asymmetric boron / nitrogen / sulfur helicene-type multiple resonance-thermally activated delayed fluorescence material in organic solar cells. This multiple resonance-thermally activated delayed fluorescence material has a sulfur pseudoplanar helicene structure, composed of different donor units such as phenothiazine and diphenyl acridine. For the first time, it is used as a solid photovoltaic promoter, doped into fullerene or non-fullerene binary organic solar cell devices, significantly improving the energy conversion efficiency and stability of the devices. Specifically, when doped into PM6:Y6 binary non-fullerene organic solar cells, the energy conversion efficiency of the organic solar cell increased from 16.01% to 17.17%, and when doped into PM6:PC... 71 In BM binary fullerene organic solar cells, the energy conversion efficiency of organic solar cells increased from 8.49% to 9.30%.

The application discloses a synthesis method and application of a kind of phenothiazine leuco photo-caged compound, and relates to the application in the field of biological medicine.The compound is formed by using oxygen, sulfur and selenium containing phenothiazine leuco as matrix, connecting different functional groups by amide bond, especially STAT3 inhibitor molecules, forming a photo-controllable release platform that can be activated under near infrared light 650 or 660nm.In addition, the dye has good biocompatibility and low cytotoxicity, and experiments prove that it also has excellent imaging and treatment effect on specific tumor cells.

The application discloses a novel BODIPY-based near-infrared ratio fluorescent probe for targeted detection of endoplasmic reticulum hypochlorous acid and a preparation method and application thereof. The fluorescent probe is 4-((4-(3,7-di(2-(10-butyl-10H-phenothiazine-3-yl)vinyl)-1,9-dimethyl-5H-4-(dipyrromethene difluoroboron-10-yl)phenoxy)methyl)benzenesulfonamide, which is abbreviated as PTB-BSA. The probe PTB-BSA can specifically recognize hypochlorous acid, and the color of the probe PTB-BSA solution added with hypochlorous acid rapidly changes from green to dark blue under sunlight. In addition, the fluorescence emission spectrum of the probe PTB-BSA is obviously blue-shifted, and the fluorescence emission wavelength is shifted from 752 nm to 681 nm. The linear range of the probe for hypochlorous acid is 0-60 muM, the detection limit is as low as 35 nM, and the response time is within 10 s. The probe exhibits good selectivity for hypochlorous acid, and is not affected and interfered by other anions, biological thiols and active oxygen. More importantly, the probe can also target the endoplasmic reticulum, and can realize organelle-level detection of the content of hypochlorous acid. This has very important significance for in-depth study on the action process of hypochlorous acid in a biological body.

The invention relates to synthesis and application of a hypochlorous acid fluorescent probe based on phenothiazine cinnamyl aldehyde. The structural formula of the probe is shown in the specification. The invention provides a preparation method for synthesizing the fluorescent probe by taking phenothiazine (PTZ) and 4-(dimethylamino) cinnamyl aldehyde as raw materials. The fluorescent probe has the characteristics of high sensitivity, quick response, low cytotoxicity and the like, and is suitable for detecting hypochlorous acid. Firstly, the fluorescent probe has weak fluorescence at the position of 560 nm, after the fluorescent probe responds to hypochlorous acid, the fluorescence at the position of 560 nm is remarkably enhanced, and good linear correlation is shown in the range of 1-35 [mu] M; in addition, the fluorescent probe has good selectivity on hypochlorous acid, and is not influenced by various kinds of cations, anions, biological mercaptan and active oxygen; furthermore, the interaction between the fluorescent probe and hypochlorous acid is rapid, and the response time is within 30s; finally, in cells, the fluorescent probe shows low toxicity and can be used for detecting hypochlorous acid in living cells.

The present invention discloses a phenothiazine-based photoactivated RNA labeling photosensitizer, and its preparation method and application. The structure of the photosensitizer dye is shown in Formula I. The photosensitizer dye is based on phenothiazine photosensitizer dyes and is obtained by non-covalently linking furan fragments to obtain FNBS. The photosensitizer generates reactive oxygen species under light, which can oxidize furan to cause it to open its ring and then combine with nucleic acids in the cytoplasm to achieve the purpose of labeling. At the same time, it induces nucleic acid damage under light to cause cell pyroptosis, thereby achieving photoimmunotherapy. The photosensitizer has a strong killing ability against tumor cells. The anti-tumor effect of the photosensitizer dye includes the two parts of photosensitizer dye generating reactive oxygen species to kill tumor cells and cell death caused by destroying nucleic acids; inducing cell pyroptosis, causing cell immunogenic death. The advantage of the present invention is that the photosensitizer can not only achieve photodynamic therapy but also cause cell pyroptosis, thereby achieving photoimmunotherapy and improving the efficacy of tumor treatment.

The application discloses a kind of benzimidazole compounds and its application, belong to crop growth regulation technical field.The benzimidazole compound structural formula is;Wherein, R1 It is phenothiazine group, NH2 Or halogen;R2 It is H, CH3 Or F;R3 It is phenothiazine group, CH3, NH2, NO2 Or halogen.Benzimidazole compound is 5-nitro-2-(N-phenothiazine group)-1H-benzimidazole, 5-(N-phenothiazine group)-1H-benzimidazole or 2-bromo-5-amino-1H-benzimidazole.The application is modified to different sites of benzimidazole, designs new benzimidazole compound.The raw material of this preparation method is easy to obtain, low in cost, and operation is relatively simple.This benzimidazole compound can promote crop growth and inhibit the activity of pathogenic bacteria, and has good development prospect.

The invention belongs to the field of organic synthesis and medicinal chemistry, and particularly relates to a synthesis method of a 12-bromine-5, 9-di-tert-butyl naphtho-indolizine phenothiazine compound and an anti-tumor application of the 12-bromine-5, 9-di-tert-butyl naphtho-indolizine phenothiazine compound. Through efficient and simple one-pot bromination reaction, selective functionalization of a C12 site is realized, and the first brominated derivative based on a naphtho-indolizine phenothiazine skeleton is constructed. In-vitro anti-tumor activity research shows that the target compound shows broad-spectrum anti-tumor activity: the target compound has remarkable inhibitory activity (IC50 values are respectively 1.52 mu M, 3.14 mu M and 4.19 mu M) on cervical cancer Hela, lung adenocarcinoma A549 and prostatic cancer PC-3 cells, and the activity is improved by 3.5-16.5 times compared with that of a clinical drug cis-platinum. Preliminary toxicity evaluation shows that the toxicity to normal human umbilical vein endothelial cells (HUVEC) is lower than that of tumor cells, and good selectivity is achieved. The invention provides an important lead compound for developing novel anti-cancer drugs.

The application belongs to the technical field of pharmaceutical chemistry, and discloses a phenothiazine sulfonamide compound shown in a general formula (I) or a salt thereof, a preparation method and application thereof. The compound, a pharmaceutically acceptable salt, an isomer, a prodrug, a co-crystal complex, a hydrate or a solvate thereof can be used as an agonist of a retinoic acid receptor-related orphan receptor-gamma t (RORgamma t).

The application discloses a method for preparing fluorine-containing diphenylmethane compounds by using sulfur hexafluoride as a fluorination reagent, and belongs to the technical field of organic chemical synthesis. The preparation method comprises the following steps: (1) mixing a photocatalyst, a solvent and a reducing agent, and performing ultrasonic treatment to obtain solution A; mixing a reaction substrate and the solvent to obtain solution B; the photocatalyst is one or more of 4CzIPN, Ir[dF(CF3)ppy]2(dtbpy))PF6, 9-thioxanthone and 10-phenylphenothiazine; the reaction substrate is a compound with a structural formula of R1 and R2 are both H, alkoxy or halogen; (2) mixing the obtained solution A and solution B in a sulfur hexafluoride gas atmosphere, and performing reaction under blue light illumination, and the fluorine-containing diphenylmethane compounds are obtained. The method has the beneficial effects that the fluorine-containing diphenylmethane compounds are efficiently prepared by using sulfur hexafluoride as the fluorination reagent, and by selecting raw materials and catalysts with certain proportions; the reaction raw materials are cheap; the preparation process is safe, mild, has good substrate compatibility and high preparation efficiency.

The application discloses a visible light driven deaminative bromosulfonylation method. The method comprises the following steps: under the protection of inert gas, sulfonamide shown in formula (I), alkyne shown in formula (II), 10H-phenothiazine and carbon tetrabromide are dissolved in an organic solvent, tert-butyl nitrite and trifluoroacetic acid are added, and reaction is carried out under visible light irradiation to obtain (E)-beta-bromo vinyl sulfone shown in formula (III); wherein, R 1 is selected from aryl, substituted aryl, heteroaryl, alkyl or cycloalkyl; R 2 is selected from aryl, substituted aryl, heteroaryl, alkyl or cycloalkyl; R 3 is selected from alkyl; the photocatalyst is 10H-phenothiazine; the bromine source is carbon tetrabromide; the organic solvent is 1,4-dioxane, N,N-dimethylformamide, dimethyl sulfoxide or acetonitrile; and the wavelength of visible light is 420-520 nm. The method has the advantages of high stereoselectivity, mild reaction condition and wide substrate application range.

The application belongs to the field of latent fingerprint imaging, and more particularly relates to a preparation method of a water-soluble AIE functional molecule and application thereof in latent fingerprint imaging. The water-soluble AIE molecule has the following general structural formula: wherein R1 is triphenylamine, N-phenylcarbazole, N-phenylphenothiazine, N-phenylphenoxazine, 10H-phenoselenoxazine or 10-phenyl-10H-phenoselenoxazine; Ar l is an onium salt containing pyridine, quinoline or isoquinoline. The prepared developer has simple preparation method, high aggregate state luminescent efficiency, fast latent fingerprint imaging speed, high detection sensitivity and imaging resolution, and excellent latent fingerprint imaging effect on strong spontaneous light substrates, dark substrates, rough surface substrates, semi-absorptive substrates and absorptive substrates.