18 results about "Thienopyrrole" patented technology

The invention relates to the technical field of photovoltaic cells, in particular to a hole transport material and a preparation method thereof, a solar cell and an optoelectronic device. The hole transport material comprises a hole transport polymer, and the hole transport polymer has at least one of repetitive units shown in formulas (I)-(III). According to the hole transport material provided by the invention, thienopyrrole, carbazole and phenothiazine are adopted as conjugated units of the hole transport polymer, a cyano phosphate group is adopted as an anchoring unit of the hole transport polymer, and through the synergistic effect of the conjugated units and the anchoring unit, the efficiency and stability of a perovskite solar cell are improved, and the service life of the perovskite solar cell is prolonged.

The invention relates to the field of organic photovoltaic materials, in particular to synthesis and application of a D-A-D type structure organic photovoltaic material intermediate modified by a novel fused ring thiophene as a pi bridge. Alkyl-modified thienopyrrole is used as a pi-bridge electron donating unit (D), and a benzothiadiazole derivative is used as an electron withdrawing group (A). Through a Stille coupling reaction, the organic photovoltaic material intermediate with a D-A-D type structure, which is modified by thienopyrrole as a pi bridge based on undecyl, is obtained. An ultraviolet-visible absorption spectrum test shows that the compound has relatively strong light harvesting capability. The material provided by the invention has good solubility and film-forming property and a wide spectral response range, and is expected to be used as an acceptor material of an organic solar cell.

The present invention belongs to the field of perovskites and organic solar cells, and discloses an acridine-based self-assembled hole-selective material having a structure of formula I: #imgabs0#X and Y are each independently selected from hydrogen, alkyl, amino, nitro, alkoxy, and halogen; L is selected from (C2-C18) alkyl, phenyl, naphthyl, anthracenyl, thienyl, benzothienyl, dithienothiophene, dithienothiopyrrole, carbazolyl, and fluorenyl; and A is selected from one of the following groups: #imgabs1# The self-assembled hole-selective material of the present invention has the advantages of high energy level matching, suitable steric hindrance effect, and suitable connecting group length that is conducive to regulating film morphology. It can simultaneously passivate surface defects of a nickel oxide hole transport layer, induce perovskite crystal growth, and reduce energy loss caused by interfacial charge recombination. The self-assembled hole-selective material is applied to an inverted perovskite solar cell device to obtain a solar cell with higher photovoltaic performance and high efficiency and stability.

Disclosed are polymorph, crystal form III and crystal form IV of compound (S)—N-[5-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-4,6-dioxo-5,6-dihydro-4H-thieno[3,4-c]pyrrole-1-yl]acetamide.

The application discloses a thienopyrrole fused benzothiadiazole dichroic dye and application thereof. The dichroic dye takes thienopyrrole fused benzothiadiazole as an acceptor unit, a benzene ring and thienyl or its derivative as a donor unit, and a structural formula of the dichroic dye is shown in the following formula: wherein R1 represents C 1～8 alkyl, R2 represents C 3～10 branched or straight chain alkyl, C 3～10 branched or straight chain alkoxy, C 3～10 branched or straight chain alkylamino, and n is an integer of 1-3. The dichroic dye has the advantages of wide ultraviolet absorption range and good ultraviolet stability, and can be used for preparing high-performance intelligent vehicle windows.

Disclosed is crystalline Form I of the compound (S)-N-[5-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-4,6-dioxo-5,6-dihydro-4H-thieno[3,4-c]pyrrol-1-yl]acetamide.

Connection of the general formula I characterized by the fact that QO or S is preferred, QS is preferred; R1 is selected from the group consisting of alkoxy, alkyl, fluorinated alkyl, partially fluorinated alkyl, and aryl; X1 and X2 are independently N or C-R4; wherein R4 is selected from the group consisting of H, halogen, alkoxy, branched or linear, cyclic or open-chain alkyl, alkenyl, and aryl, wherein H may be substituted; A1 is a group with formula Ia, where * denotes the connection to the compound of the general formula I; Z1 is selected from the group consisting of O, S, Se, and N-R5. where R5 is selected from the group consisting of H, alkoxy, alkyl, fluorinated alkyl, partially fluorinated alkyl, and aryl; Y1 N or C-R6, where R6 is selected from the group consisting of H, halogen, alkoxy, branched or linear, cyclic or open-chain alkyl, alkenyl, and aryl, where H may be substituted in each case; Y2N or C-R7, where R7 is selected from the group consisting of H, halogen, alkoxy, branched or linear, cyclic or open-chain alkyl, alkenyl, and aryl, wherein H may be substituted; and wherein R6 and R7 may be homocyclic or heterocyclic linked to each other in the form of a ring structure; R2 is selected from the group consisting of H, halogen, alkoxy, alkyl, fluorinated alkyl, partially fluorinated alkyl, branched or linear, cyclic or open-chain alkyl, amino, aryl, heteroaryl, alkenyl, and an electron-withdrawing alkyl group with at least one C=C double bond, where H may be substituted by CN or F; A2 is a group with the formula Ib, where * denotes the connection to the compound of the general formula I; Z2 is selected from the group consisting of O, S, Se, and N-R8, where R8 is selected from the group consisting of H, alkoxy, alkyl, fluorinated alkyl, partially fluorinated alkyl, and aryl; Y3N or C-R9, where R9 is selected from the group consisting of H, halogen, alkoxy, branched or linear, cyclic or open-chain alkyl, alkenyl, and aryl, where H may be substituted in each case; Y4N or C-R10, where R10 is selected from the group consisting of H, halogen, alkoxy, branched or linear, cyclic or open-chain alkyl, alkenyl, and aryl, wherein H may be substituted; and wherein R9 and R10 may be homocyclic or heterocyclic linked to each other in the form of a ring structure; and R3 is selected from the group consisting of H, halogen, alkoxy, alkyl, fluorinated alkyl, partially fluorinated alkyl, branched or linear, cyclic or open-chain alkyl, amino, aryl, heteroaryl, alkenyl, and an electron-withdrawing alkyl group with at least one C=C double bond, where H may be substituted by CN or F.

The present invention discloses a method for the prevention or treatment of Sjögren's syndrome comprising the step of administering a prophylactic or therapeutically effective amount of N-[5-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-4,6-dioxo-5,6-dihydro-4H-thieno[3,4-c]pyrrole-1-yl]acetamide, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof to an individual in need thereof. Equation (I)

The present disclosure relates generally to thioeno[3, 2-], pyrrole derivatives pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and / or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus.

To provide a method for treating disease.SOLUTION: The present disclosure relates generally to specific compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and / or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus. As described in detail and specifically demonstrated herein, it is surprisingly found that, the present invention achieves remarkable effects, which could not have been easily predicted by those skilled in the art based on the prior art.SELECTED DRAWING: None

A method for preventing or treating Sjögren's syndrome. The method comprises administering to a subject in need an effective amount of N-[5-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl) ethyl]-4,6-dioxo-5,6-dihydro-4H-thieno[3,4-c]pyrrole-1-yl]acetamide, a stereoisomer thereof or a pharmaceutically acceptable salt thereof.

The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and / or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus.

The application belongs to the technical field of biological medical materials, and provides a H-aggregated pyrrole derivative, a preparation method and application thereof, the derivative has a molecule with a donor-acceptor (D-A) structure, the donor structure is an aromatic amine derivative, the bridge structure is a dithieno[3,2-b:2,3-d]pyrrole, and the acceptor structure is 2-(3-cyano-4,5,5-trimethylfuran-2(5H)-methylene)malonitrile or 2-[3-cyano-4-methyl-5-phenyl-5-trifluoromethyl-2(5H)-furyl]-malonitrile. Through the synergistic molecular design of "strong donor-large plane bridge-strong acceptor", the application successfully guides the self-assembly of the molecule to form a stable H-aggregate, realizes the "integration" and "synergistic enhancement" of the type I photodynamic and photothermal properties on a single material, and thus can synchronously trigger two kinds of efficient treatment mechanisms under single-wavelength near-infrared light irradiation.

The present invention discloses a scorpion-type non-doped organic small molecule hole transport material and its preparation method and application. The hole transport material is based on dithiophene-thiophene-pyrrole as an acceptor unit, and triphenylamine donor units are introduced into the thiophenes at both ends of the acceptor unit and the middle pyrrole, respectively, to form a scorpion-type hole transport material. The material has the advantages of good planarity, high degree of conjugation, high hole mobility and adjustable energy level, and is suitable for the hole transport layer of perovskite solar cells. The preparation method of the present invention has the characteristics of easy operation, simple and easy to obtain raw materials, low cost, high yield, etc. The perovskite solar cell using the hole transport material of the present invention is composed of a perovskite layer, a hole transport layer, an electron transport layer and an electrode, and the hole transport layer adopts a scorpion-type non-doped organic small molecule hole transport material. The current density of the perovskite solar cell is 24.44mA / cm 2 , the open circuit voltage is 0.82V and the photoelectric conversion efficiency is 16.85%.

The application belongs to the technical field of polymer synthesis and organic photovoltaic cells, and discloses a preparation method of thienopyrrole diketone polymer, which is a three-component polymer containing a TPD unit and prepared by one-step polymerization based on dialdehyde, cyclic imide and elemental sulfur. The polymer has unique optical properties, high molecular weight, and a weight average molecular weight ranging from 5000 to 20000 g / mol. The synthesis method has the advantages of easy raw materials, simple operation steps and few by-products.

The present invention relates to novel thienopyrrolotriazinacetamide compounds of Formula (I): wherein R1, R2 and R3 are defined herein, which inhibit NOD-like receptor protein 3 (NLRP3) inflammasome activity. The invention further relates to the processes for their preparation, pharmaceutical compositions and medicaments containing them, and their use in the treatment of diseases and disorders mediated by NLRP3.