The invention provides a donor-acceptor-donor-acceptor-donor oligothiophene derivative taking dithienopyrrole as a molecular center. The chemical structural formula of the derivative is shown in formula I in the description, synthesis comprises the steps that 2,6-di(trimethyl-tin)-N-iso-octane-dithieno[3,2-b:2',3'-d]pyrrole and 4,7-dibromine-[1,2,5]thiadiazole[3,4-c]pyridine react to synthesize an intermediate (2,6-2{(4-(7-bromine-[1,2,5]thiadiazole[3,4-c]pyridine)}-N-iso-octane-dithieno[3,2-b:2',3'-d]pyrrole); and then the (2,6-2{(4-(7-bromine-[1,2,5]thiadiazole[3,4-c]pyridine)}-N-iso-octane-dithieno[3,2-b:2',3'-d]pyrrole) reacts with 2-(trimethyl-tin)-5-(4-n-hexylphenyl)thiophene to obtain the target oligothiophene derivative. The oligothiophene derivative has a narrow band gap, a lowHOMO energy level, good solubility and film formation, and is expected to be used as an organic semiconductor material in the preparation of organic thin film field effect transistors, organic light emitting diodes and organic solar cell devices.