11 results about "Terthiophene" patented technology

The invention relates to application of 2, 2 ': 5', 2 ''-trithiophene-5-formaldehyde in preparation of medicines for treating osteoporosis, and belongs to the technical field of biological medicines. The application of 2, 2 ': 5', 2 ''-trithiophene-5-formaldehyde in preparation of the medicine for treating osteoporosis is found for the first time, and especially the excellent application of 2, 2 ': 5', 2 ''-trithiophene-5-formaldehyde in preparation of the medicine for treating osteoporosis of postmenopausal women is found. In the cell level, the 2, 2 ': 5', 2 ''-trithiophene-5-formaldehyde shows obvious osteogenesis promotion and adipogenesis inhibition activity. On the animal level, the 2, 2 ': 5', 2 ''-trithiophene-5-formaldehyde can significantly improve bone mass loss of mice with osteoporosis caused by OVX, and promotes bone formation while inhibiting bone resorption. The result shows that the 2, 2 ': 5', 2 ''-trithiophene-5-formaldehyde has a good osteoporosis treatment effect, provides a novel anti-osteoporosis medicine for clinic, and has a wide application prospect and a relatively high application value.

One aspect provides a pharmaceutical composition for preventing or treating metabolic diseases or autoimmune diseases, the composition comprising a novel terthiophene derivative compound or a pharmaceutically acceptable salt thereof. The pharmaceutical composition effectively inhibits monoamine oxidase B (MAO-B), and thus can be used in various fields for the prevention or treatment of metabolic diseases, such as obesity and fatty liver, or autoimmune diseases, such as rheumatoid disease.

The invention discloses a polypeptide nanoring material and a preparation method thereof, and belongs to the technical field of high polymer materials. The preparation method comprises the following steps: co-assembling poly (gamma-benzyl ester-L-glutamic acid) (PBLG) and achiral triphenylamine derivatives {N, N-bis (2-methylphenyl) aniline (MTPA), 4-(5-aldehyde-2, 2 ': 5', 2 ''-terthienyl)-N, N-bis (2-methylphenyl) aniline (MTTH) or 4-[5-(2, 2-dicyanovinyl) thiophene-2-yl]-N, N-bis (2-methylphenyl) aniline (MTTV)} to obtain the poly (gamma-benzyl ester-L-glutamic acid)-N, N-bis (2-methylphenyl) aniline derivative. According to the present invention, the emission of multi-color circularly polarized light (CPL) (near ultraviolet to deep red light, 370-660 nm) is achieved, and the maximum luminescence asymmetry factor (glum) is up to 1.1 * 10 <-2 >, and is improved by more than 30% compared with the prior art. Meanwhile, the generation inhibition rate of reactive oxygen species (ROS) is increased to 98% or above through a compact nanostructure of the material, the problem of phototoxicity of traditional triphenylamine derivatives is solved, and the material is suitable for high-resolution biological imaging and targeted diagnosis and treatment.

The present application relates to a kind of efficacy composition for preventing and treating tobacco root-knot nematode, fertilizer synergist and its application, the efficacy composition includes α-triphenyl and slightly fermented fertilizer;The slightly fermented fertilizer is respectively with the stem of continuation of stem, the stem of three-leaf bidens and the stem of dandelion as raw material, after cooking treatment, steam explosion treatment, microbial fermentation liquid soaking treatment, fermentation treatment, dry after the three kinds of fermentation products obtained by mixing are obtained.The slightly fermented fertilizer prepared by using specific preparation process can significantly improve the killing efficiency of α-triphenyl on root-knot nematode, and the combination of α-triphenyl and α-triphenyl can synergize, so that the killing effect of α-triphenyl on root-knot nematode is still very good at low use concentration, and the mortality of root-knot nematode is as high as 90%.

The application discloses a composite photoelectrode for glucose content detection and a preparation method and application thereof, and belongs to the technical field of photoelectrochemical analysis. A BiOI film is electrochemically deposited on the surface of a conductive substrate (such as pretreated FTO conductive glass) in a nitric acid solution system; a bismuth vanadate photoelectrode is obtained by calcining and alkali treatment of the substrate on which dimethyl sulfoxide solution containing vanadyl acetylacetonate is dropped; a polyterthiophene (pTTH) layer is photoelectrodeposited on the surface of the bismuth vanadate by using acetonitrile electrolyte; a multistage composite structure is obtained by depositing a nickel oxide layer through an aqueous electrolyte and calcining treatment, so that the nickel oxide / polyterthiophene / bismuth vanadate composite photoelectrode is obtained. In this way, the nickel oxide / polyterthiophene / bismuth vanadate composite photoelectrode prepared by the application has high carrier separation efficiency and excellent catalytic stability, and provides an analysis method with simple steps for effective voltage detection of glucose.

The application relates to a planar triarylamine molecule and a synthesis method thereof. A bridged triarylamine is selected as a molecular core, a terthiophene with high carrier mobility and passivation is selected as a peripheral group, a synthesized molecule is named as FTPA-T3, and a structural formula is as follows: the synthesis steps are few, the reaction condition is simple, the product yield is high, and the structure is stable. The synthesized FTPA-T3 dye has high molecular solubility and carrier mobility; the molecule has a good conjugated plane, and the hole transport efficiency is increased. Meanwhile, the compound has high thermal stability, and the thermal decomposition temperature is higher than 400 DEG C. The compound has potential application prospect as a hole transport material.

The invention discloses a terpyridyl ferrous catalyst derived from terthiophenes and application of the terpyridyl ferrous catalyst in photocatalysis of CO2. The catalyst has a structure as shown in a formula I. According to the catalyst, a light capture unit terthiophene is integrated to a terpyridyl ferrous catalytic center through molecular design to form an integrated structure with a self-sensitization function, and the preparation method comprises the following steps: condensing 2, 2 ': 5', 2 ''-trithiophene-5-formaldehyde and 2-acetylpyridine under an alkaline condition to obtain a ligand; and coordinating with ferrous chloride to obtain the target catalyst. According to the present invention, in the photocatalytic CO2 reduction reaction, the efficient catalysis can be achieved without the addition of the noble metal photosensitizer, the CO conversion number is up to 642, the selectivity exceeds 98%, and the low-cost and high-activity new scheme is provided for solving the dependence on the noble metal in the prior art.

A method for preparing a composite photoelectrode for glucose content detection includes the following steps: adding potassium iodide and bismuth nitrate pentahydrate to a nitric acid solution, adding p-benzoquinone to ethanol, and mixing to obtain electrolyte A; depositing a BiOI thin film on FTO conductive glass using an electrochemical method; dripping a dimethyl sulfoxide solution of vanadium acetylacetonate onto the surface of the BiOI thin film, calcining it, immersing it in NaOH solution, rinsing it, and drying it to obtain a BVO photoelectrode; adding lithium perchlorate and terthiophene to acetonitrile to obtain electrolyte B, and performing photoelectrodeposition on the BVO photoelectrode using an electrochemical method to obtain the composite photoelectrode. The preparation method of this invention is simple and safe to operate, uses readily available materials, and can be mass-produced; the prepared composite photoelectrode, combined with photoelectric detection technology, can detect glucose content, exhibits high stability, simple steps, rapid response, and high sensitivity, providing a new analytical method for glucose content determination.

The invention belongs to the technical field of photocatalysis, discloses a covalent triazine framework photocatalyst based on trithiophene as well as a preparation method and application of the covalent triazine framework photocatalyst, and is used for solving the technical problems that a reaction system for preparing bis (imidazo [1, 2-alpha] pyridine-3-yl) selenide needs high temperature and a strong oxidant and the like. The covalent triazine framework is composed of a plurality of repeated structural units, the structural formula of the structural units is shown in the formula I, and in the formula, '-' represents the omitted repeated structural units; the catalyst can be used for catalytic synthesis of bis (imidazo [1, 2-alpha] pyridine-3-yl) selenide. The activity of the 3S-CTF constructed by the method disclosed by the invention in a reaction for photocatalytic synthesis of bis (imidazo [1, 2-alpha] pyridine-3-yl) selenide is 2.12 times that of 0S-CTF (a similar photocatalyst without a trithienyl group). Meanwhile, the 3S-CTF photocatalyst has good reusability, and the activity of the 3S-CTF photocatalyst is basically unchanged after the 3S-CTF photocatalyst is repeatedly used for five times.

The application discloses a synthesis method and application of a fluorescent probe for lipase detection, and the fluorescent probe has the following structural formula; the synthesis method comprises the following steps: under the action of inert gas protection, a catalyst and alkali, triphenylol compound and a fatty chain or an aromatic ring organic acid are reacted in an organic solvent at 25-100 DEG C for 8-24h; after the reaction is stopped, dichloromethane and water are added to carry out extraction; organic phases are combined, dried, filtered, and the solvent is removed under reduced pressure; and the product is separated and purified; the fluorescent probe is basically non-fluorescent by itself, releases bright fluorescence after reacting with lipase, and can realize rapid detection of bacteria by using the characteristics that most bacteria secrete lipase in the growth and reproduction process.

The invention discloses a method for detecting total polar substances of edible oil based on a trithiophene type fluorescent probe, which comprises the following steps: dissolving the trithiophene type fluorescent probe in 1, 4-dioxane to prepare a probe solution; the method comprises the following steps: adding a probe solution dissolved in 1, 4-dioxane into edible oil containing different contents of total polar substances, recording fluorescence intensity through a fluorospectro photometer, and constructing a linear standard curve through a linear relation between the content of the total polar substances and the fluorescence intensity; and adding the probe solution into the edible oil, recording the change of the fluorescence intensity, and substituting the change into the standard curve to obtain the total polar substance content of the edible oil. The probe (Z)-3-(5 '-(4-(bis (4-methoxyphenyl) amino) phenyl)-[2, 2': 5 ', 2'-terthienyl]-5-yl)-2-(5-(trifluoromethyl) pyridine-2-yl) acrylonitrile selectively detects the polarity of the edible oil, red fluorescence is quenched after the polarity of the edible oil is increased, and the probe can be used as a fluorescent probe for detecting the polarity of the edible oil.