Disclosed is a refining technique of base oil regenerated from used lubrication oil, and the refining technique comprises the following steps of 1, removing solid waste, which includes removing solid waste from used lubrication oil by centrifugation; 2, solvent pretreatment, which includes extracting mixed impurities and moisture through a solvent and obtaining raw oil after removing upper oil; 3, flocculation treatment, which includes turning mixtures obtained from step 2 into a mixture of flocculation; 4, atomospheric distillation; 5, carrying out reduced pressure distillation; 6, carrying out rectification; 7, solvent refining: putting oil produced from a rectifying column into a treatment tank and when the height of the oil level in the treatment tank reaches 65%-75% of the height of the treatment tank, adding by mass 10%-40% of 1-Methyl-2-pyrrolidinone, and carrying out solvent refining. The refining technique of base oil regenerated from used lubrication oil has the advantages of low investment and high yield efficiency, meanwhile, the refining technique accords with the requirement of environmental protection, reduces vacuum residuum by 15%, improves product yield, facilitates the overhauling of equipment, prolongs the production period, largely improves production efficiency and appearance quality of minus line oil, and helps to obtain high quality regenerated base oil.