9results about How to "Medication convenience" patented technology

This invention belongs to the pharmaceutical field and relates to a human nerve growth factor composition. This invention provides a human nerve growth factor composition that can be administered via multiple routes, maintains good stability without cryopreservation, and does not require fixed accessories, simplifying operation and improving the convenience of medication.

The invention provides a dexmedetomidine transdermal patch which comprises a backing layer, a release film and a polymer matrix layer arranged between the backing layer and the release film, the polymer matrix layer comprises dexmedetomidine, povidone and a pressure-sensitive adhesive, based on the total mass of the polymer matrix layer, the dexmedetomidine accounts for 4-10%, the povidone accounts for 5-10%, and the pressure-sensitive adhesive accounts for 5-10%. The povidone accounts for 2-12%, and the pressure-sensitive adhesive accounts for 78-94%; the pressure-sensitive adhesive comprises at least one of polymers containing carboxyl or hydroxyl functionalization.

The invention provides application of p-hydroxycinnamic acid in preparation of a medicine for preventing and treating noise-induced deafness. The invention has the advantages that the p-hydroxycinnamic acid has the advantages of strong pertinence, high safety, convenience in medication, good patient compliance and the like, not only effectively overcomes the defects of the existing noise-induced hearing loss treatment medicines, but also provides a brand-new preventive treatment thought; important clinical popularization significance and industrial application prospects are realized.

The utility model provides a mouse holder, specifically relates to the field of animal experiment device, including base, the support plate of setting on the base, be equipped with the fixed cylinder of horizontal setting on the support plate, still include the conical head sleeve of fixed mouse head, the eye hole of being equipped with for mouse eye exposure in the both sides of head sleeve, the nose hole of being equipped with for mouse nose exposure in the one end of head sleeve, the other end of head sleeve is connected with the one end of fixed cylinder, the other end in fixed cylinder is equipped with the baffle, the lower part of baffle is equipped with the tail hole convenient for mouse tail to leak out, the upper part of baffle is equipped with fastening bolt, the upper side of fixed cylinder is equipped with the strip hole convenient for fastening bolt reciprocating sliding, be equipped with the air bag for fixing mouse body in fixed cylinder, the inner side wall of air bag and fixed cylinder forms the interlayer for inflation, the outer side wall of fixed cylinder is equipped with inflation pipe, and is equipped with inflation bag and exhaust valve with inflation pipe is matched. The utility model is convenient for the operation such as orbit venous blood sampling of mouse eye.

The application provides a compound omeprazole dry suspension and a preparation method thereof, and relates to the technical field of pharmaceutical preparations.The compound omeprazole dry suspension comprises the following raw materials: omeprazole, sodium bicarbonate, magnesium silico-aluminate, hard stearic acid modified hydrotalcite, low acyl gellan gum, hydroxypropyl methyl cellulose and trehalose.The application provides a compound omeprazole dry suspension and a preparation method thereof, and the compound omeprazole dry suspension with specific particle size is prepared through specific proportioning of auxiliary materials and a specific preparation process, and the stability and solubility are significantly improved.

The invention relates to the technical field of medical instruments, and discloses an airway administration device for respiratory medicine nursing, comprising a main body, the outer surface of the main body is fixedly connected with an air delivery pipe, the top of the main body is rotatably connected with a sealing cover, the interior of the sealing cover is fixedly connected with a support column, and the support column penetrates through the sealing cover to the interior of the main body. The outer surfaces of the supporting columns are rotationally connected with rings. Supporting blocks located on supporting rods can be aligned through first arc-shaped blocks so as to push corresponding movable plates and elastic plates to be attached to the inner wall of the main body, in this way, the medicine applying process is more convenient, and meanwhile the situation that in the using process, due to the fact that a baffle is not arranged on the side close to an air conveying pipe, liquid medicine which is not completely atomized is splashed out is prevented; therefore, the utilization efficiency of the liquid medicine is improved.

The invention belongs to the technical field of medicines, particularly discloses a masitinib oral cavity soluble film dosage form composition, and also discloses an oral cavity soluble film dosage form prepared from the composition and a preparation method of the dosage form. The masitinib oral soluble film dosage form composition provided by the invention comprises an active component and an auxiliary material, the active component comprises at least one of masitinib or pharmaceutically acceptable salt, prodrug, metabolite, solvate, crystal and deuterated substance thereof, and the auxiliary material comprises a film forming material. The masitinib oral soluble film provided by the invention has the characteristics of fast disintegration and good taste, and improves the compliance of medication of patients.

The invention discloses a 3-aryl coumarin derivative as well as a preparation method and application thereof, and the preparation method comprises the following steps: reacting substituted 2-bromobenzaldehyde with a substituted aryl acetic acid compound to obtain a substituted E-2, 3-diaryl acrylic acid compound; and in the presence of cuprous oxide and potassium carbonate, heating and reacting in N, N-dimethylformamide to obtain the 3-aryl coumarin derivative. The 3-aryl coumarin derivative disclosed by the invention can be combined with BRD4, has remarkable inhibitory activity on the BRD4, has a protective effect on primary myocardial cells caused by ischemia reperfusion, can inhibit proliferation, migration and invasion of cardiac fibroblasts, and can inhibit ferroptosis of hypoxia / reperfusion injury myocardial cells; the compound can be used for preparing medicines for treating diseases related to abnormal BRD4 activity.

The invention belongs to the technical field of bacterium sampling, and provides a burn wound surface unit area bacterium sampling device which comprises a pushing unit, a bearing unit and a sampling unit, the pushing unit comprises a protection block, a sliding groove is horizontally formed in one side of the protection block, a butt joint groove is formed in the bottom of the protection block, and the sliding groove communicates with the butt joint groove; a first telescopic rod is fixedly connected into the sliding groove, a containing hole is horizontally formed in the output end of the first telescopic rod, the bearing unit comprises a storage box, and the top end of the storage box is attached to the inner wall of the butt joint groove; after sampling is completed, a first telescopic rod is started, so that the output end of the first telescopic rod gradually retracts, the stress of a second elastic piece and the stress of a third elastic piece are reduced, the second elastic piece and the third elastic piece push a sealing plate and an adjusting plate to reset correspondingly, and a sampling pipe is sealed in a shell; bacteria in the air are prevented from entering the sampling tube, so that the situation that a detection result is inaccurate is avoided.