48 results about "Tissue edema" patented technology

The invention provides systems and methods for neuromuscular electrical stimulation to muscle tissue. Stimulation electrodes may be provided on a stimulation pad, configured to provide electrical stimulation to a target tissue. A system for neuromuscular electrical stimulation may also include pressure generating mechanisms that may provide a compressive force to a region with the target tissue, thereby removing some excess third space fluid from the region.

The invention relates to a preparing method of sodium aescinate, an external use preparation comprising the sodium aescinate,and application thereof, in particular to the preparing method of the sodium aescinate, preparation of the external use preparation and application to the preparation of medicine for preventing or treating tissue edema due to trauma. The preparing method is characterized by comprising extraction and separation and purification steps, wherein for the extraction, buckeye powder is extracted by 0-80-percent of ethanol or methanol solution (preferably methanol solution), the separation and purification step comprises the ion exchange chromatography by using inorganic sodium salt water solution as a flowing phase. The method has the advantages that the purity of prepared products is high, the production period is short, the cost is low, the problems such as environment pollution are avoided, and the like, and the method conforms to the development trends of preparing natural safe and high-purity aescin.

The invention discloses a quantitative fast frequency-locked magnetic resonance imaging method. Data acquisition of magnetic resonance imaging signals corresponding to different spin lock pulses in acontinuous scanning period is completed, and the data fills the same position in K space, so that T1rhomapping images finally obtained corresponding to the different spin lock pulses have high matching degree and can be used for judging tissue fibrosis indexes and diagnosing a tissue edema state; the effects of arrhythmia, uneven breathing and the like on the quality of the T1rhomapping images areminimized, and physical state and ability to suspend breathing and the like of a tester are not strictly required, so that scanning time required to obtain the T1rhomapping images is greatly shortened and the research and promotion of a T1rhomapping imaging technology in the field of clinical medical detection is further developed; in addition, the spin lock pulses alternate in positive and negative phases in adjacent RF excitation pulses, thereby effectively reducing artifacts due to magnetic field uniformity.

The present invention relates to an ultrasound equipment for treating edema, and more particularly, to an ultrasound equipment to relieve symptoms of edema or repair cellular and tissue edemas by generating 20˜400 mW/cm² of low intensity ultrasound and use thereof.

The ultrasound equipment according to the present invention comprises a main control unit equipped with a control unit for ultrasound generation for generating a 20˜400 mW/cm² of low intensity ultrasound, an ultrasound generator for generating ultrasound according to the operating state of the main control unit, an ultrasound vibrator vibrating according to the value of ultrasound data inputted from the ultrasound generator, and a probe for delivering ultrasound energy to a treatment site, and when the ultrasound equipment is used, it is possible to treat edema by increasing permeability in blood vessels.

The invention discloses a method for establishing an acute lung injury animal model, and relates to the technical field of bioengineering. The method for establishing the acute lung injury animal model comprises the following steps: anesthetizing and fixing an experimental animal; inducing acute lung injury of the experimental animal by combining hydrochloric acid with mechanical ventilation; andevaluating the degree of acute lung injury. According to the method, acute pathological injury of the lung of the experimental animal is induced by combining hydrochloric acid with mechanical ventilation, the animal model of acute lung injury can be constructed, and the animal model shows typical characteristics of acute lung injury, such as dyspnea, lung tissue edema and lung tissue fibrosis. Themodel can be used for basic research in the related field of acute lung injury, and lays an experimental animal foundation for exploring the pathogenesis of acute lung injury.

The present invention relates to medicine, more particularly to pharmaceutical or cosmetic compositions, used for application on the skin, including the region of eyes, as well as on the lips and the mucosa of nasal, oral and laryngeal cavities of the man or the animal, with the purpose of preventing or reducing itch and local reaction from stings of insects, in particular mosquitoes, wasps, horse-flies etc. Local reaction from stings of insects is understood as pain, burning sensation, tissue edema, and hyperemia (redness around the sting site). The pharmaceutical or cosmetic composition, preventing or reducing the itch and the local reaction from the stings of insects, contains soluble salt or mixture of soluble salts of one or several rare earth elements, triethylene glycol, glycerine, polyethylene oxide, ethanol, sodium (potassium) hydroxide and water. When applied on the skin or the mucosa immediately after a sting, the composition leads within several tens of seconds to relief or entire disappearance of the itch, the pain and the burning, prevents edematization and then promotes disappearance of the edema. When the claimed composition is applied preventively, a prophylactic action on preventing or reducing manifestation of the itch and the local reaction from the stings is provided for 1-2 hours after the composition application.

The invention discloses bilirubin nanoparticles for treating acute pancreatitis and a preparation method thereof. The nanoparticles are mainly composed of silk fibroin, bilirubin, genipin and ceramide. The method comprises the steps that firstly, the bilirubin, the genipin and the ceramide are dissolved in a mixed organic reagent; secondly, the silk fibroin is dissolved in an aqueous solution, then the mixed solution of the bilirubin, the genipin and the ceramide is slowly added into the silk fibroin solution dropwise and continuously stirred, the organic solvent is removed through dialysis, and an obtained nanoparticle suspension is diluted with pure water to obtain the bilirubin nanoparticles. The bilirubin nanoparticles can be used for treating acute pancreatitis and relieving tissue edema caused by pancreatitis, can be applied to preparation of medicines for treating acute pancreatitis, and has wide clinical application prospects.

The invention relates to the technical field of medical instruments, and discloses an extendable anti-reflux pancreatic stump anastomosis supporting tube which solves the problems that in the current pancreatic stump anastomosis operation, the risk of cracking cannot be avoided in pancreatic intestine or pancreatic stomach anastomosis, anastomotic fistula is caused, and then pancreatic fistula occurs. The extendable anti-reflux pancreatic stump anastomosis support tube comprises a supporting outer sleeve, one end of the supporting outer sleeve is connected with an anti-reflux assembly, a supporting inner sleeve is connected into the end, away from the anti-reflux assembly, of the supporting outer sleeve, and a connecting film is connected between the supporting inner sleeve and the supporting outer sleeve. When an anastomotic stoma does not crack, the support tube device only plays a role of the anti-reflux support tube; when the anastomotic stoma cracks, the support tube can still maintain the drainage function of a main pancreatic duct-small intestine cavity or gastral cavity, and when edema of peripheral tissue of the anastomotic stoma gradually fades away, the anastomotic stoma gradually heals, and the support tube gradually returns to the unstretched state; and pancreatic fistula is avoided by applying the support tube, and extensibility is achieved.

The invention researches the anti-inflammatory activity of DSS (Dextran Sulfate Sodium) inducted colitis model for paeoniflorin and paeoniflorin metabolism pigment I. An experiment result indicates that the paeoniflorin metabolism pigment I has a good treatment effect on ulcerative colitis. Compared with a control group and a paeoniflorin group, a C57BL/6 mouse which orally takes the paeoniflorinmetabolism pigment I, the paeoniflorin metabolism pigment I is characterized in that a colon tissue damage degree is lightened, the mouse colon tissue damage degree of the low and high dosage medication administration team of the paeoniflorin metabolism pigment I is lightened, a tissue structure is clear in level, the infiltration of inherent layer inflammatory cells is reduced, the amount of cup-shaped cells is relatively increased, muscularis mucosa does not contain tissue edema and hyperaemia, and tissue forms are obviously recovered. The paeoniflorin metabolism pigment I is proved to havea good treatment effect on the ulcerative colitis.

The invention belongs to the technical field of medicine, and specifically discloses an acute lung injury treating pharmaceutical composition, and uses of a compound having a structure represented bythe following formula defined in the specification in preparation of acute lung injury treating drugs, wherein R1, R2 and R3 can be the same or different groups. Patients with acute lung injury have pathological changes such as pulmonary alveolus structure destruction, pulmonary interstitial congestion and edema, massive inflammatory cell infiltration and the like. According to the present invention, the acute lung injury treating pharmaceutical composition can improve the symptoms of the patients with acute lung injury, reduce lung tissue edema and inflammatory cell exudation, and reduce thehistopathological score of lung tissue, wherein the longer the action time, the more significant the protection effect on lung.

The invention relates to a bandaging and fixing device after a skin-grafting surgery, and belongs to the technical field of medical apparatuses. The bandaging and fixing device is composed of an adsorption loop, a pressing cover and an air bag, the air bag is arranged on the bottom of the pressing cover, a pressing plate is movably arranged between the air bag and the pressing cover, and the adsorption ring is arranged on the periphery of the lower surface of the pressing plate arranged on the periphery of the air bag. The bandaging and fixing device can adjust bandaging pressure by controlling inflating volume of the air bag, balance pressure suffered by the grafted skin, so that the grafted skin can tightly fit skin tissue defect wound surfaces, and effusion can be absorbed by the adsorption loop arranged on the pressing cover, so that it is beneficial to subside tissue edema and promote granulation tissues neogenesis in the wound surfaces; survival rate of the grafted skin is further improved; the problem is solved that existing uneven pressure causes avascular necrosis of the grafted skin, and the bandaging and fixing device after the skin-grafting surgery has the advantages ofsimple structure and good practicability, and is particularly applicable to bandaging and fixing use after the skin-grafting surgery.

The invention discloses an adjustable suture including a micro locking mechanism and a suture main body. The micro locking mechanism is composed of a shell body, a limit plate and a pressure limitingwheel. The outer wall at one end of the shell body is fixedly connected with a suture fixing ring, and one end of the suture main body is wound on the ring wall of the suture fixing ring for fixed connection. The adjustable suture has the beneficial effects that after suturing or ligating a tissue, the adjustable suture can be stretched along with the tissue edema and other conditions and can alsobe shortened with the tissue edema subsiding, so as to make the tissue keep relatively long-lasting pressure in the healing process; the suture is a low-tension suture and has slow cutting effect onthe tissue. On the other hand, with the arranged micro locking mechanism and the height elasticity of the suture, after the tissue is sutured or ligated and fixed, the suture can be loosened when thetension is greater than the set range, so that the tension can reach the set range, the suture can be tightened when the tension is less than the set range, and the tension can reach the set range.

The invention discloses a microcirculation pulse blood flow monitoring system and method used for liquid therapy and capacity management, and belongs to the technical field of medical treatment monitoring. The monitoring system comprises a data collecting module, a storage module and a comparison module. At different times, repeated positioning is conducted on blood capillaries in the same monitored region, and blood vessel image data is collected and stored; the measurement data of blood vessel images collected at different times are compared, the number of blood vessels where pulse blood flow occurs and/or the speed of pulse blood flow and/or the frequency of pulse blood flow occurrence are used as indexes for making capacity management and liquid therapy accurate, and the problem is solved that liquid therapy and capacity management lack clinical golden indexes. Through the monitoring system, a heart failure, pulmonary edema and tissue edema of lungs caused by excessive transfusionare avoided, the burden of kidneys is reduced, transfusion time is shortened, treatment costs are lowered, and the pains of patients are relieved.

The invention discloses ephedra, cassia twig, scorpion, centipede and woodlouse powders for treating lumbar intervertebral disc protrusion through a two-step method, and relates to traditional Chinese medicine powders for treating lumbar sprain and lumbar disc herniation. The ephedra, cassia twig, scorpion, centipede and woodlouse powders can treat lumbar sprain through the two-step method. In the first step, an ephedra and cassia twig juicing method is adopted to prompt a nucleus pulposus protrusion to retract so as to release the oppressed state of adjacent nerve roots and eliminate tissue edema around spinal cord and the spinal stenosis, so that pains of a patient that arrests sweating can be reduced immediately, and immediate effect can be achieved. In the second step, the scorpion, centipede and woodlouse powders are taken orally for one or two courses of treatment, each course of treatment contains ten days so as to restore broken fiber rings, and the disease can be healed thoroughly without recurrence. Ephedra and cassia twig are taken and ground to obtain fine powders that are 100 meshes (monopack), and scorpion, centipede and woodlouse are taken and ground to obtain fine powders that are 100 meshes (monopack). The ephedra and cassia twig powders are taken orally in the first day in the first course of treatment, and the patient covers a quilt for sweating. The scorpion, centipede and woodlouse powders are taken orally from the second day to the eleventh day, are taken two times a day in morning and evening respectively. After the first course of treatment, the patient suffered from the disease for a long time can take the powders for the second course of treatment, so as to achieve healing.

The invention relates to a use of nicotinamide mononucleotide in preparation of a drug for prevention and/or treatment on rtPA vascular complication. rtPA is an important thrombolytic drug for treating acute myocardial infarction, pulmonary embolism and cerebral infarction, can easily produce untoward effects in clinical application and has obvious tendency of destroying a blood vessel barrier structure and inducing vascular complication such as bleeding. Based on a mouse vascular complication model caused by injection of rtPA, the protective effect of nicotinamide mononucleotide on rtPA-damaged blood vessels is researched. An experimental result shows that nicotinamide mononucleotide can significantly improve mouse blood extravasation caused by injection of rtPA, reduce tissue edema and increase expression of a blood vessel tight junction protein so that nicotinamide mononucleotide can resist rtPA-caused angiolysis and vascular complication.

A corneal tissue culture system and a corneal tissue culture method for increasing corneal endothelial cell density, healing of damaged corneal endothelial cell, and stimulating corneal endothelial cell proliferation are disclosed. The corneal tissue culture system comprises a tissue culture medium and a tissue culture dish to reduce metabolic pressure and reduce corneal tissue edema.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine formula for antagonizing cerebral vascular excessive dilatation and a preparation method thereof.The traditional Chinese medicine formula is composed of 1-35 parts of lignum dalbergiae odoriferae, 1-35 parts of radix curcumae, 1-35 parts of rhizoma chuanxiong, 1-35 parts of rhizoma acori graminei, 1-35 parts of radix aucklandiae and 1-35 parts of radix salviae miltiorrhizae. The formula is used for antagonizing cerebrovascular dilatation caused by various pathological factors, inhibiting loss of vascular smooth muscle and reducing dilatation exudation and hemorrhage, so that perivascular tissue edema is inhibited, oppression pain caused by vascular dilatation is relieved, and general families can prepare the traditional Chinese medicine by themselves through the provided preparation method and equipment.