Application of ectoine and/or hydroxyectoine to preparation of burn and scald treatment drug

Abstract

The invention discloses application of ectoine and / or hydroxyectoine to preparation of a burn and scald treatment drug. The ectoine and / or hydroxyectoine can effectively promote wound healing of burnsand scalds, shorten healing time, regulate and control collagen synthesis, prevent scar tissue caused by ratio imbalance and abnormal accumulation of collagen fiber, inhibit release of inflammatory factors, reduce wound exudation and pus accumulation, relieve wound tissue edema, reduce wound sensitivity, relieve pain and pruritus in a debridement process and a wound healing process and alleviatepatients' pain.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to the application of ectoine and / or hydroxyectoine in the preparation of medicines for treating burns and scalds. Background technique [0002] Burns mainly refer to the damage of skin, mucous membranes, and even deep tissues caused by heat (including hot liquid, steam, high-temperature gas, flame, electric energy, chemical substances, radiation, hot metal liquid or solid, etc.). One of the common accidental injuries. Skin tissue damage caused by heat can cause degeneration and necrosis of different layers or depths of the skin due to different heat temperature and contact time. In mild cases, it mainly manifests as damage to the skin and subcutaneous tissue, and in severe cases, it can damage muscles, bones and internal organs. Extensive burns can involve various organs and systems throughout the body, and can even cause shock and death. [0003] The annual i...

AI Technical Summary

Problems solved by technology

Among them, the ingredients related to traditional Chinese medicine are relatively complex, the stability is poor, and most of the traditional Chinese medicine scald medicines are oily, which affects the cleaning of the wound surface during dressing change, which in turn aggravates wound damage and affects wound healing.

Although antibacterial western medicines have significant antibacterial effects, long-term use is likely to cause systemic complications (such as neutropenia and nephrotoxicity, etc.)