Application of a kind of Mirabilis extract and skin external preparation containing the same

A technology of Mirabilis mirabilis extract and extract, which is applied in skin care preparations, medical preparations containing active ingredients, and cosmetic preparations, etc., which can solve the problems of lack of active substances, achieve free radical scavenging activity, and improve anti-inflammatory effects. The expression of senescence protein and the effect of anti-aging

Active Publication Date: 2022-07-12
JALA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] The technical problem solved by the present invention is aimed at the lack of active substances that can be used to improve the skin's anti-oxidation and anti-aging capabilities in the prior art, and provides an application of mirabilis extract and an external skin preparation containing it

Method used

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  • Application of a kind of Mirabilis extract and skin external preparation containing the same
  • Application of a kind of Mirabilis extract and skin external preparation containing the same
  • Application of a kind of Mirabilis extract and skin external preparation containing the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0082] Example 1 Preparation of Mirabilis Extract

[0083] 100 g of dried purple jasmine flowers were weighed, pulverized, added with 100 mL of 70% ethanol, and immersed in cold for 12 hours until the material was fully infiltrated by the solvent. Then heat at 60°C, extract for 2 hours, filter, collect the extract, and extract 3 times in total. The three extracts were combined and dried under reduced pressure to obtain 15 g of crude extract. 1 g of the crude extract was weighed, dissolved in water, passed through macroporous adsorption resin AB-8, eluted with 1 column volume of water, and the washing solution was discarded. Then, it was eluted with 30% ethanol of 5 times the column volume, and the eluate was concentrated and evaporated to dryness to obtain 0.5 g of dry powder of jasmine flower extract.

Embodiment 2

[0085] According to the following components and dosages, it is formulated into a lotion, and the percentage refers to the weight percentage of each component in the lotion:

[0086] Glycerin 5%, Butylene Glycol 3%, Betaine 1%, Panthenol 0.5%, Dipotassium Glycyrrhizinate 0.1%, Allantoin 2.0%, Macrogol-32 0.5%, Hydroxyethyl Cellulose 0.15-0.2 %, IS-45 0.4%, Xanthan Gum 0.15%, Fragrance 0.03%, and Mirabilis Extract 0.005%; the rest were made up to 100% with deionized water.

[0087] According to the conventional preparation method of lotion in the art, the external preparation for skin in this example was prepared.

Embodiment 3

[0089] According to the following components and dosages, it is formulated into an essence, and the percentage refers to the weight percentage of each component in the essence:

[0090] Glycerin 5%, Butylene Glycol 3%, Panthenol 1%, Dipotassium Glycyrrhizinate 0.1%, Allantoin 0.1%, Niacinamide 4%, Hydroxyethyl Cellulose 0.05%, Methylparaben 0.15%, Phenoxy Ethanol 0.3%, Xanthan Gum 0.2%, Acrylic Resin Pemulen TR-2 0.3%, Fragrance 0.05% and Mirabilis Extract 0.1%; the rest were made up to 100% with deionized water.

[0091] According to the conventional preparation method of essence in the art, the external preparation for skin in this example was prepared.

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Abstract

The present invention provides an application of Mirabilis extract and a skin external preparation containing the same. The application is specifically, the application of Mirabilis extract in the preparation of one or more of antioxidants, melanin synthesis inhibitors, elastic fiber hydrolysis inhibitors and anti-skin aging protein expression up-regulators. Mirabilis extract, especially Mirabilis flower extract, has the effect of scavenging free radicals, inhibiting tyrosinase activity, inhibiting elastase activity and increasing the expression of anti-aging proteins in human fibroblasts, and can regulate the synthesis of collagen in the dermis , has anti-aging effect.

Description

technical field [0001] The invention relates to the application of a Mirabilis extract and a skin external preparation containing the same. Background technique [0002] With the continuous development and maturity of the skin care product market, more and more brands have emerged. Consumers want to see effective skin care effects for the efficacy of skin care products. Therefore, research on the efficacy mechanism of skin care products actives is required. The level needs to be improved. As the interpretation of the efficacy mechanism becomes more and more in-depth, it cannot be limited to simply describing the appearance, but requires the integration of cutting-edge biotechnology. With the continuous development of cell biology technology, the discovery of skin biology It has also been deepened, and more targets and regulatory mechanisms related to the functional structure of the skin have been discovered. [0003] The skin is the largest organ of the human body, covering...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61Q19/08A61Q19/02
CPCA61K8/9789A61Q19/08A61Q19/02A61K2800/782
Inventor 李慧摩根多斯桑托斯章漳蒋丹丹秦优
Owner JALA GROUP CORPORATION
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