12 results about "Elastase activity" patented technology

The invention relates to the technical field of cosmetics, in particular to a blue copper peptide-containing composition and application thereof in cosmetics. The composition comprises the following components in parts by mass: 1 part of blue copper peptide; 0.5 to 5 parts of tetrahydromethylpyrimidine carboxylic acid; 0.05 to 0.5 part of sodium hyaluronate; and 0.05 to 0.5 part of beta-glucan. Preferably, the composition further comprises allantoin and lactobionic acid, based on 1 part by mass of the blue copper peptide, the content of the allantoin is 0.1-0.5 part, the content of the lactobionic acid is 0.2-1.0 part, and the mass ratio of the allantoin to the lactobionic acid is 1: (2-4). In-vitro efficacy experiments prove that the specific combination and proportion can generate a remarkable synergistic effect, and meanwhile, the capabilities of inhibiting the activity of elastinase and promoting epidermal cell repair are improved, so that the excellent dual effects of wrinkle resistance and skin barrier repair are realized. The composition can be used for preparing cosmetics such as essence, emulsion and face cream.

The invention belongs to the technical field of cosmetics, and particularly relates to a Keemun black tea-root composition with repairing and anti-aging effects as well as a preparation method and application of the Keemun black tea-root composition. The Keemun black tea root extract, the elm root extract and the acanthopanax root extract in a specific amount ratio range are scientifically compounded, the synergistic effect among the components is remarkable, the effect limitation of a single component is effectively overcome, and the synergistic enhancement of anti-aging and repairing effects is realized. Experiments and exploration find that the composition can significantly inhibit the activity of elastase and delay the skin aging process caused by elastin degradation; meanwhile, the transdermal moisture loss can be obviously improved, and the skin barrier function and the self-repairing capability are enhanced. Therefore, the Keemun black tea-root composition disclosed by the invention is outstanding in overall effect, has the characteristics of naturalness, high efficiency and mildness, and accords with the development trend of modern skin care products.

The invention relates to the technical field of cosmetics, in particular to a firming and relieving composition and application thereof.The skin care composition is prepared from peach resin extract, inonotus obliquus extract, purslane extract, sodium hyaluronate cross-linked polymer and porphyridium cruentum extract. The composition obtained by compounding the raw materials can significantly inhibit the activity of elastinase, has a certain inhibition effect on the activity of hyaluronidase, has significant tightening and soothing effects, and is mild and non-irritating.

The present invention relates to a protein hydrolysate isolated from black soldier fly larvae and, more specifically, to a cosmetic composition for skin whitening and skin wrinkle reduction, comprising an anionic peptide as an active ingredient. The protein hydrolysate of black soldier fly larvae, according to the present invention, has an excellent skin absorption rate, exhibits an effect on skin whitening by inhibiting melanin synthesis and tyrosinase activity, and has an excellent effect of preventing or reducing skin wrinkles by enhancing skin elasticity through collagenase inhibitory activity and / or elastase inhibitory activity.

The present application relates to a kind of skin care compositions and its application in the preparation of cosmetics with antioxidant, firming anti-wrinkle and anti-aging, belong to the technical field of cosmetics.The skin care composition includes royal jelly extract, plum blossom extract, ergothioneine and hydroxyl pinacolyl retinoate.The royal jelly extract, plum blossom extract, ergothioneine and hydroxyl pinacolyl retinoate in a certain amount range Compounding can produce synergistic effect, so that skin care composition has strong DPPH free radical scavenging capacity, can efficiently neutralize skin excess active oxygen, alleviate oxidative stress damage, while effectively inhibiting elastase activity, slow down elastin degradation and loss, improve skin relaxation problem.Can also significantly improve the cell survival ability under UVB light damage, resist ultraviolet-induced photoaging, multi-dimensional synergistic play antioxidant, firming and anti-wrinkle and repair anti-aging effect.

The application discloses a method for extracting jasmine flowers by using a combined solvent, which comprises the following steps: preparing the combined solvent, ultrasonic dispersion, constant temperature oscillation extraction, and filtration and centrifugation. The combined solvent is prepared by using a combination of citric acid, ascorbic acid, lactic acid and glycerol, and the weight ratio of the four components is 2:1:1:5. The combined solvent can balance the extraction amount of total flavonoids and total phenols in jasmine dried flowers, and improve the extraction efficiency. The jasmine flower extract prepared by the method has the effects of removing free radicals, inhibiting tyrosinase and elastase activities, delaying skin aging, and whitening, and has no irritation to the skin.

The present invention relates to a composition comprising Fructobacillus fructosus PRC-1 KCTC15271BP, a culture medium thereof, or extracellular vesicles thereof. The composition comprising Fructobacillus fructosus PRC-1 KCTC15271BP, a culture medium thereof, or extracellular vesicles thereof, according to the present invention, exhibits excellent antioxidant activity, and thus can be used as an antioxidant composition, exhibits an excellent effect on skin whitening by inhibiting melanin production, can exhibit improved efficacy against skin pigmentation diseases, facilitates wound healing and skin regeneration through wound recovery and the like, reduces skin wrinkles by inhibiting elastase activity, and exhibits therapeutic efficacy on skin wrinkle-related diseases. Therefore, the present invention is remarkably effective as a food, a pharmaceutical composition, and a cosmetic composition.

The invention belongs to the technical field of cosmetics, and particularly relates to a peppermint essential oil nano-emulsion, a preparation method thereof and application of the peppermint essential oil nano-emulsion in preparation of anti-wrinkle products. The preparation method of the peppermint essential oil nano-emulsion comprises the following steps: step 1, taking 15%-25% of peppermint essential oil, 10%-25% of PEG-40 hydrogenated castor oil and 50%-70% of purified water in percentage by volume, and mixing; step 2, ultrasonic treatment; and step 3, stirring and emulsifying at room temperature. The nano-emulsion provided by the invention can inhibit the activity of elastase and delay the degradation of elastin. In a UVA injury model, the peppermint essential oil nano-emulsion can remarkably promote secretion of human fibroblast collagen. In conclusion, the peppermint essential oil nano-emulsion prepared by taking the PEG-40 hydrogenated castor oil as the surfactant has good anti-wrinkle and skin-care effects.

The application discloses a preparation method of a tea fermentation product with anti-aging efficacy for cosmetics, and obtains a cosmetic yeast strain with cellulase, xylanase and lignin peroxidase production capacity through strain screening. The release of antioxidant and anti-aging substances in tea leaves is improved through fermentation and extraction of tea leaves by the preferred yeast strain, and the anti-aging performance of the fermentation product is further improved through the fermentation of gluconacetobacter kombuchia. Compared with conventional tea extracts, the tea fermentation product has more excellent performance in terms of antioxidant, elastase activity inhibition, collagenase activity inhibition, AGEs yield inhibition, human fibroblast protection and repair, and is suitable for use in skin care products such as essence, emulsion and cream with anti-aging efficacy.

To provide an elastase activity inhibitor comprising a plant extract of high safety as an active ingredient.SOLUTION: An elastase activity inhibitor comprises, as an active ingredient, an extract derived from one or two or more plants selected from the group consisting of chamomile, mugwort, and adlay.SELECTED DRAWING: None

This invention discloses a bovine colostrum exosome, its preparation method, composition, and applications. The preparation method includes pretreatment, microfiltration clarification, ultrafiltration concentration and impurity removal, density gradient ultracentrifugation purification, washing, and resuspension to obtain high-purity exosome BCE-01. This exosome exhibits no cytotoxicity or skin sensitization at safe concentrations and possesses multiple functions, including promoting skin cell migration and repair, inhibiting the release of inflammatory factors, upregulating the expression of genes involved in collagen and other matrix synthesis, and inhibiting elastase activity. This invention also provides cosmetic and pharmaceutical compositions containing BCE-01. Human trials have demonstrated that this composition can significantly improve skin barrier function, enhance elasticity, reduce wrinkles, and soothe redness. This invention particularly provides innovative raw materials and complete solutions for developing multi-functional, highly safe skincare products.

The application discloses an essence containing a firming and anti-wrinkle composition and a preparation method thereof, and belongs to the field of cosmetic preparations; the essence containing the firming and anti-wrinkle composition comprises the following components: a firming and anti-wrinkle composition, palmitoyl tripeptide-5, hydroxypropyl tetrahydropyrane triol and a solvent; wherein the firming and anti-wrinkle composition comprises boletus extract, radix paeonia extract, radix valerianae extract and cyclocarya paliurus extract. The essence containing the firming and anti-wrinkle composition provided by the application has an inhibition rate of elastase activity of 65% or more, has a significant promoting effect on type I collagen synthesis, and has an excellent effect on free radical elimination.