39 results about "Oral Drops" patented technology

Hypertonic sugar compositions administered by other than ingestion and swallowing or intravascular injection, such as by intranasal spray or drops, intraocular drops or ointment, oral spray, intraotic spray or drops, lozenges, chewable tablet, chewing gum, or gargle, pulmonary inhalation, vaginal or rectal suppositories, or transdermal creams, ointments, lotions, or patches, are effective to open the blood-brain barrier to permit entry into the central nervous system of a co-administered chemical compound, such as a nutrient or a therapeutic or diagnostic agent. In this way, the compositions and methods of the invention increase the therapeutic or diagnostic efficacy of such chemical compounds.

The invention discloses a nasal cavity drop for treating diabetes and a preparation method. The nasal cavity drop comprises solvent and accessories, and is characterized in that the solvent contains a compound of calcium phosphate nano particles and exenatide, the weight ratio of the calcium phosphate nano particles to the exenatide in the compound is 1-10:0.1-10, and the content of the exenatide in the solvent is 0.01 to 0.5 milligram per milliliter. The preparation method for the nasal cavity drop comprises the following steps: mixing aqueous solutions of calcium salt, phosphate, citrate and exenatide to form the compound of the calcium phosphate nano particles and the exenatide, adding the accessories which are frequently used for aqueous agent into the mixture, detecting and adjusting the pH of the solution, and finally forming the nasal cavity drop, wherein the weight ratio of the calcium phosphate nano particles to the exenatide in the compound is 1-10:0.1-10, and the content of the diluted exenatide in the solvent is 0.01 to 0.5 milligram per milliliter.

The invention discloses a device for automatically cleaning and transporting feces from a sheep house, comprising a sheep house, a manure collection tank arranged at the bottom of the sheep house, and a gathering device provided at the bottom of the manure collection tank, and is characterized in that: the outside of the manure collection tank is provided with There is a track groove on the manure falling port. The height of the track groove is higher than the bottom surface of the septic tank. There are stoppers on the side of the track groove. Under the action of the gathering device, the feces are gathered and scraped to the falling At the manure outlet, the feces fall from the manure outlet, and the lower side of the manure outlet is provided with a manure receiving belt corresponding to the manure outlet. One end of the manure conveying belt is connected to the manure belt through the manure cleaning board, and the other end is passed through another The manure cleaning board is connected to the manure collecting tank, and then the manure is transported into the manure collecting tank. The manure collected and scraped by the device does not need to be cleaned manually, and is automatically transported to the manure collecting tank or other manure collecting equipment, avoiding manual shoveling The high-intensity work of manure and manure pulling effectively reduces the cost of breeding.

A Chinese medicine in the form of dripping pill for treating cold, fever, sore throat, etc is prepared from scutellaria root, forsythia fruit, isatis leaf and liquorice root.

The invention provides a desloratadine citrate disodium oral liquid preparation as well as a preparation method and an application thereof. The oral liquid preparation of the invention comprises desloratadine citrate disodium and pharmaceutically acceptable auxiliary materials, wherein the concentration of the desloratadine citrate disodium in the oral liquid preparation is 0.01-1.0% (w / v), and the pH is 2.0-8.0; and the desloratadine citrate disodium oral liquid preparation comprises an oral solution, a syrup or an oral drip. The desloratadine citrate disodium oral liquid preparation mainly fills the market blank of children antiallergic drugs in the age of six to eleventh months, guarantees the safety of the children medication, and can also meet the requirements of patients with different age groups.

The invention relates to a liquid loratadine composition, in particular to a liquid medicine composition. The liquid loratadine composition comprises, by weight, loratadine 10 parts and oil 50-2000 parts. The invention further relates to a pharmaceutical preparation which can be in a mode of soft capsules, oral liquid or drops. The liquid loratadine composition can be taken orally, has good pharmaceutical property and can be suitable for large population including infants.

A Chinese medicine in the form of dripping pile for treating upper respiratory tract infection, tonsillitis, acute bacterial dysentery, enteritis, etc is prepared through savatier monochasma herb, oldenlandia herb and doyflower herb.

A quantitative drop of the orally taken iodine solution is prepared from iodine, potassium iodide, water, flavouring and antiseptic. Its preparing process is also disclosed. It features use of quantitative dripping tube (or pump) and jet tube, resulting in correct dosage.

The invention provides levocetirizine hydrochloride oral drops good in taste and a preparation method thereof and belongs to the field of drug preparation. The levocetirizine hydrochloride oral drops are prepared from levocetirizine hydrochloride material, a solvent, a corrective, a preservative, a stabilizer, and a colorant, and the liquid medicine is quantitatively pumped out through a mechanical snap valve by using a quantitative dropper pump; the levocetirizine hydrochloride material has a concentration of 0.1-5 mg / ml in the drops herein. The liquid quantity of quantitative drops per snap is 0.1-2 ml. The levocetirizine hydrochloride oral drops are taken by an adult two to three times a day, 1-2 ml for each time. The levocetirizine hydrochloride oral quantitative drops are of a solvent type preparation and have the advantages medicine is distributed in a molecular form in liquid, may be quickly absorbed after administration, and acts fast; that dosage of the quantitative drops given by using the quantitative dropper pump is accurate, scientific and reasonable; the quantitative drops are sprayed directly into the mouth through a spray tube such that administration is greatly facilitated; the levocetirizine hydrochloride oral drops are good in taste and easy for a patient to accept.

A Chinese medicine in the form of dripping pill for treating influenza, pharyngolaryngitis, pneumonia, bacterial dysentery, acute enterogastritis, appendicitis, etc is prepared from glabrous sarcandra herb and matrix.

A Chinese medicine in the form of dripping pill for treating acute dysentery, enteritis, upper respiratory tract infection, sore throat, tonsillitis, etc is prepared from cloves leaf and matrix.

The present invention belongs to the field of medicine preparation technology, and is one kind of gel dripping preparation and aerosol containing asiaticoside and sodium hyaluronate. The gel drippingpreparation and aerosol is different from gel preparation in that it can form one film on the surface of wound. The gel dripping preparation and aerosol is relatively thin, easy to form film on wound,and suitable for wound of patient incapable of being painted with gel directly. The present invention also provides the preparation process.

A Chinese medicine in the form of dripping pill for treating influenza, pharyngolaryngitis, pneumonia, bacterial dysentery, acute enterogastritis, appendicitis, etc is prepared from glabrous sarcandra herb and matrix.

The orally taken Ribavirin dropping pill contains Ribavirin 1-12 mg each and proper amount of matrix. The matrix may be one of polyglycol-6000, polyglycol-4000, polyoxyethylene monostearate, sodium stearate, etc. or their composition. The preparation process includes mixing Ribavirin and heated and smelted matrix, dropping the mixture at 50-120 deg.c into condensing agent to form dropping pill, eliminating condensing agent, inspection and packing. The condensing agent is one or several of dimethyl silicon oil, liquid paraffin, rape seed oil and tea seed oil. The Ribavirin dropping pill may be used in preventing and treating viral respiratory tract infection and other viral infection, and has the features of high efficiency and less side effect.

The invention relates to a liquid loratadine composition, in particular to a liquid medicine composition. The liquid loratadine composition comprises, by weight, loratadine 10 parts and oil 50-2000 parts. The invention further relates to a pharmaceutical preparation which can be in a mode of soft capsules, oral liquid or drops. The liquid loratadine composition can be taken orally, has good pharmaceutical property and can be suitable for large population including infants.

A Chinese medicine in the form of dripping pile for treating upper respiratory tract infection, tonsillitis, acute bacterial dysentery, enteritis, etc is prepared through savatier monochasma herb, oldenlandia herb and doyflower herb.

The invention discloses a blood circulating and pain relieving dropping pill with functions of activating blood circulation to dissipate blood stasis and relieving swelling and pain, and in particular relates to a drug composition (namely oral dropping pill preparation) which is based on traditional Chinese medicine set prescription (namely blood circulating and pain relieving capsules and blood circulating and pain relieving tablets) and is modified by dosage form. The invention aims at providing the drug composition oral preparation (namely the blood circulating and pain relieving dropping pill), and according to the dropping pill, the defect that the conventional oral drug preparation for treating the diseases can be overcome, the bioavailability is high, the drug can be released rapidly, the effect can be shown rapidly, the toxic and side effects are small, the drug content is high, the taking dosage is small and accurate, the drug taking is convenient, the cost is low, and the dropping pill can be taken out conveniently.

The invention relates to a medicinal oral preparation with the functions of heat clearing and detoxicating, heat clearing and detoxicating, invigorating blood circulation, repercussion and pain relieving, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, no contamination in production. low cost of manufacture. The preparation is prepared from hairy holly root extract and indomethacin as the active medicinal composition and corresponding adjuvant through specific process.

The invention relates to a medicinal oral preparation with the functions of activating blood circulation, removing stasis and treating coronary disease and angina pectoris, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying. The medicine is prepared through the conventional drop pill preparing process.

The invention discloses oral drops for acute and chronic nasosinusitis and rhinitis of children. The oral drops are prepared by adding honey, sodium benzoate, citric acid, sucralose and other auxiliary materials into nine crude drugs including platycarya strobilacea infructescence, spica prunellae, flos chrysanthemi indici, rhizome ligustici wallichii, radix angelicae, flos magnoliae, radix saposhnikoviae, radix astragali and radix glycyrrhizae. The oral drops are reasonable in formula according to the traditional Chinese medicine formula theory; the medicinal materials supplement each other and play a synergistic role; the oral drops are particularly suitable for acute and chronic nasosinusitis and rhinitis of children, and can relieve systemic symptoms, adjust systemic functions and treat locally infected focuses; meanwhile, the natural refined honey is added, so that the effects of strengthening the middle warmer and moistening dryness of the honey can be exerted, the bitter taste of the traditional Chinese medicine can be improved, and the balance of aroma, sweetness, sourness and bitterness of the system is kept; and the oral drops are more suitable for children patients to take.

A Chinese medicine in the form of dripping pill for treating acute dysentery, enteritis, upper respiratory tract infection, sore throat, tonsillitis, etc is prepared from cloves leaf and matrix.

The invention relates to the technical field of drug metabolic component analysis, in particular to a method for detecting in-vivo prototype components and metabolic components of a dripping pill with a refreshing and refreshing throat. According to the present invention, based on the GC-MS and the UHPLC / Q Exactive Plus MS technology, the detection method of the in vivo prototype component and the metabolic component is established; wherein the non-volatile prototypes and metabolites are detected by adopting UHPLC-MS / MS (Ultra High Performance Liquid Chromatography-Mass Spectrometry / Mass Spectrometry) according to the following specific conditions: chromatographic conditions: an LC (Liquid Chromatography) system: Vanquishhorizon; the chromatographic column is Hypersil gold, 2.1 * 100 mm, 1.9 [mu] m; the column temperature is 40 DEG C; the sample size is 1 [mu] L; the flow rate is 0.3 mL * min <-1 >; the composition and gradient of a mobile phase are as follows: A: 0.1% formic acid-acetonitrile, and B: 0.1% formic acid-water; the mass spectrum conditions are as follows: an MS system: Orbitrap Explores 240; the scanning mode is HESI + amp; hESI <->; the taper hole voltage is 3.5 kV (HESI-), and the taper hole voltage is 2.5 kV (HESI-); the temperature of the solvent removing gas is 350 DEG C; the atomization gas is 50 arb; solvent gas removal: 10 arb; the capillary tube is 320 DEG C; the scanning range (m / z) is 100-1500; the resolution ratio (MS) is 70000; and the resolution ratio (MS / MS) is 15000. The patent develops a method for identifying in-vivo prototype drug components and metabolites of the in-vivo prototype drug components, and the metabolic pathway and excretion rule of the drug can be determined through analysis, so that a scientific basis is provided for quality control of a preparation and fundamental research of pharmacological substances.

A Chinese medicine in the form of dripping pill for treating cold, fever, sore throat, etc is prepared from scutellaria root, forsythia fruit, isatis leaf and liquorice root.

The invention discloses a heat clearing and detoxicating dripping pill for treating influenza, meningitis, and common cold, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, no contamination in production, low cost of manufacture. The medicine is prepared through the conventional drop pill preparing process.

A buccally administered dosage for assisting with the relief of common digestive complaints where the dosage formed into a hard candy dosage drop, where the dosage is a sugar base infused with a botanical derivative that has concentrated active compositions in sufficient concentration to provide a soothing effect of digestive upset, and where the drop has favorable organoleptic properties.

The present invention discloses a preparation method for oral drops of a pediatric lung-clearing composition, belonging to the field of pharmaceutical technology. The method comprises the following steps: pulverizing ephedra and subjecting it to heated ultrasonic alcohol extraction to obtain a concentrated solution; pulverizing the remaining drugs, adding water, heating to 70-85°C, and subjecting it to ultrasonic extraction; adding ethanol to the concentrated solution extracted from the remaining drugs, stirring and layering, and obtaining a supernatant; combining the supernatants of the ephedra concentrated solutions and treating them with a clarifier to obtain an impurity-removed concentrated solution; and encapsulating the impurity-removed concentrated solution with cyclodextrin to obtain the pediatric lung-clearing oral drops. The method solves the problems of low extraction rate of effective substances, high impurities, and difficulty in removing impurities in the extraction and preparation of existing traditional Chinese medicines.

The invention relates to a dexibuprofen true solution as well as a preparation method and application thereof. Specifically, the invention relates to a dexibuprofen true solution oral drop, which is prepared from 5 mg to 400 mg / ml of dexibuprofen and a cosolvent, the weight ratio of the dexibuprofen to the cosolvent is about 1.5: 1. Optionally, the dexibuprofen solution is subpackaged in a single-dose or multi-dose package. The prescription is the optimal prescription determined on the basis of a large number of optimized prescriptions, the design is reasonable, and the process is suitable for industrial production. The product is controllable in quality and stable in performance.

The invention relates to a medicinal oral preparation, i.e., cough-relieving loquat drop pill, which has the functions of yin-nourishing, arresting persistent cough, removing the phlegm and treating chronic cough and bronchitis. The drop pill has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying. The drop pill is prepared through the conventional loquat syrup preparing processes.

The invention relates to clindamycin sugar-free granules for dogs and cats and a preparation method of the clindamycin sugar-free granules, and the sugar-free granules take clindamycin phosphate as amain drug and further comprise fructo-oligosaccharide, a diluent, an adhesive, a flavoring agent and other pharmaceutic adjuvants. The clindamycin oral drops overcome the defect that existing clindamycin oral drops on the market are poor in palatability, and meanwhile the clindamycin oral drops can be used for dogs and cats suffering from diabetes and obesity. The clindamycin sugar-free granules prepared by the method disclosed by the invention are good in taste, good in solubility, more convenient to package, store, transport and carry, simple and convenient in process and suitable for industrial production.