Oral drop pill in use for clearing sway heat and toxic material, relieving inflammation and dysentery, and preparation method

A technology of Yanning dripping pills and enteritis, which can clear away heat and detoxify, can solve the problems of first-pass bioavailability of liver and intestines, is not conducive to improving the ability of patients to seek medical treatment, and harms the health of staff, so as to achieve labor protection and environmental protection. The effect of bioavailability and low labor intensity

Inactive Publication Date: 2005-08-31
北京博智绿洲医药科技有限公司
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Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation pr

Method used

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Embodiment Construction

[0029] Now with several groups of specific examples, the preparation method of Yanning dripping pills of the present invention will be further described.

[0030] Group 1: Tests with a single matrix

[0031] 1. Preparation of the drug extract: Prepare according to the preparation method 1, and obtain the dry powder of the extract containing the active ingredients of the three traditional Chinese medicines such as velvet grass, hedyotis diffusa, and commelina for future use;

[0032] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;

[0033] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0034] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Yanning Dropping Pills...

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Abstract

A Chinese medicine in the form of dripping pile for treating upper respiratory tract infection, tonsillitis, acute bacterial dysentery, enteritis, etc is prepared through savatier monochasma herb, oldenlandia herb and doyflower herb.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has heat-clearing and toxic substances removing, reducing inflammation and stopping dysentery, and is used for treating upper respiratory tract infection, tonsillitis, urinary tract infection, acute bacillary dysentery, enteritis and other diseases. A pharmaceutical composition oral drop pill preparation prepared from three kinds of traditional Chinese medicines such as Commelina chinensis and Commelina chinensis as raw materials. Background technique [0002] According to the ministerial drug standard WS 3 -Yanning Granule prepared by the preparation method given in B-0956-91 is a kind of heat-clearing and detoxifying, anti-inflammatory and anti-dysentery effect, which is used to treat upper respiratory tract infection, tonsillitis, urinary tract infection, acute bacillary dysentery, Oral tablets for diseases such as enteritis have been clinically verified and have definite curative...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61P1/12A61P11/00A61P11/04A61P13/02A61P31/04
CPCY02A50/30
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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