Blood circulating and pain relieving dropping pill with functions of activating blood circulation to dissipate blood stasis and relieving swelling and pain and preparation method of pill

A technology for reducing swelling, relieving pain, promoting blood circulation and dissipating blood stasis. It is applied in the direction of medical preparations containing active ingredients, non-central analgesics, and pill delivery. level and other issues to achieve the effect of avoiding the first-pass effect, improving bioavailability, and increasing the content of effective drugs

Active Publication Date: 2014-01-01
珠海安生凤凰制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The composition of traditional Chinese medicine injections is relatively complex. Injecting this mixture into the human body from the blood vessels and forcing the human body to metabolize it is already potentially dangerous. If it is combined with other drugs, the possible reactions are often difficult to predict
[0012] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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  • Blood circulating and pain relieving dropping pill with functions of activating blood circulation to dissipate blood stasis and relieving swelling and pain and preparation method of pill
  • Blood circulating and pain relieving dropping pill with functions of activating blood circulation to dissipate blood stasis and relieving swelling and pain and preparation method of pill
  • Blood circulating and pain relieving dropping pill with functions of activating blood circulation to dissipate blood stasis and relieving swelling and pain and preparation method of pill

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0051] Now with several groups of specific examples, the preparation method of Huoxuezhitong dripping pills of the present invention will be further described.

[0052] Group 1: Tests with a single matrix

[0053] 1. Preparation of drug extract and borneol fine powder:

[0054] Prepare according to the process of 3.1 in [Preparation Method].

[0055] 2. Substrate: polyethylene glycol (1000~20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. Pharmaceutical carrier.

[0056] 3. Proportion: taking g or kg as the unit, by weight parts, drug extract: matrix = 1:1-1:9.

[0057] 4. Preparation of dropping pills:

[0058] According to the process of 3.2 in [Preparation Method], Huoxue Zhitong Dropping Pills can be prepared.

[0059] [test results]

[0060] Experiment 1: In order to observe the difference in quality of the Huoxuezhitong drop pills prepared ...

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Abstract

The invention discloses a blood circulating and pain relieving dropping pill with functions of activating blood circulation to dissipate blood stasis and relieving swelling and pain, and in particular relates to a drug composition (namely oral dropping pill preparation) which is based on traditional Chinese medicine set prescription (namely blood circulating and pain relieving capsules and blood circulating and pain relieving tablets) and is modified by dosage form. The invention aims at providing the drug composition oral preparation (namely the blood circulating and pain relieving dropping pill), and according to the dropping pill, the defect that the conventional oral drug preparation for treating the diseases can be overcome, the bioavailability is high, the drug can be released rapidly, the effect can be shown rapidly, the toxic and side effects are small, the drug content is high, the taking dosage is small and accurate, the drug taking is convenient, the cost is low, and the dropping pill can be taken out conveniently.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a pharmaceutical composition which has the effects of promoting blood circulation and dispelling blood stasis, reducing swelling and relieving pain, and is used for bruises and congestion and reducing swelling, and particularly relates to formulating Huoxuezhitong capsules and Huoxuezhipain tablets prepared with traditional Chinese medicines Based on the dosage form, a pharmaceutical composition oral drop pill preparation is formed by reforming the dosage form. Background technique [0002] Huoxue Zhitong Capsules or Huoxue Zhitong Tablets are evolved from Huoxue Zhitong Powder. The original prescription comes from Tang Sun Simiao's "Qian Jin Fang", which consists of angelica, Sanqi, frankincense (made), borneol, wood beetle, natural copper (calcined), etc. Composed of six traditional Chinese medicines, it has been recorded in the pharmacopoeia of successive editions...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/324A61K9/20A61P29/00
Inventor 李国成阎松
Owner 珠海安生凤凰制药有限公司
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