Oral drop pill in use for clearing sway heat and toxic material, relieving inflammation and dysentery, and preparation method
A technology of dripping pills and traditional Chinese medicine, applied in medical preparations containing active ingredients, pill delivery, digestive system, etc., can solve problems such as not conducive to improving patients' ability to seek medical treatment, bioavailability of liver and intestine first-pass effect, and adverse overall health level, etc. , to achieve the effect of benefiting labor protection and environmental protection, improving bioavailability, and ensuring the quality of drugs
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Publication Date
- 2008-02-13
- Estimated Expiration
- Not applicable · inactive patent
Abstract
Description
technical field
[0001] The present invention relates to a kind of medicine composition that has heat-clearing and toxic substances removing, reducing inflammation and stopping dysentery, and is used for treating upper respiratory tract infection, tonsillitis, urinary tract infection, acute bacillary dysentery, enteritis and other diseases. A pharmaceutical composition oral drop pill preparation prepared from three kinds of traditional Chinese medicines such as Commelina chinensis and Commelina chinensis as raw materials. Background technique
[0002] According to the ministerial drug standard WS 3 -Yanning granule prepared by the preparation method given in B-095691 is a kind of heat-clearing and detoxifying, anti-inflammatory and anti-dysentery effect, which is used to treat upper respiratory tract infection, tonsillitis, urinary tract infection, acute bacillary dysentery, enteritis, etc. Oral tablets for diseases, clinically proven, have definite curative effects, and are...
Examples
Embodiment Construction
[0029] Now with several groups of specific examples, the preparation method of the dropping pills of the present invention will be further described.
[0030] Group 1: Tests with a single matrix
[0031] 1. Preparation of the medicinal extract: Prepare according to the preparation method 1, and obtain the dry powder of the extract containing the active ingredients of the three traditional Chinese medicines such as velvet grass, hedyotis diffusa, and commelina for future use;
[0032] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;
[0033] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;
[0034] 4. Prepare according to the process given in [Preparation Method] 4-7, and you can get drop pills of di...