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Oral drop pill in use for clearing away heat and toxic material, relieving inflammation and alleviating pain, and preparation method

An anti-inflammatory, pain-clearing, heat-clearing and detoxifying technology, applied in medical preparations containing active ingredients, pill delivery, digestive system, etc. It is beneficial to labor protection and environmental protection, improving bioavailability and low labor intensity.

Inactive Publication Date: 2007-11-14
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
[0007] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0027] The preparation method of Qingrexiaoyanning dripping pills of the present invention will be further described with several groups of specific examples.

[0028] Group 1: Tests with a single matrix

[0029] 1. Preparation of medicinal extract: take an appropriate amount of Jiujie tea, add water to decoct twice, filter, combine the filtrate, condense into a thick paste, dry at low temperature, and crush into fine powder to obtain the product;

[0030] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. One or a mixture of two or more pharmaceutical carriers;

[0031] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0032] 4. According to the process given in [Preparation Method] 4-7, different specifications of Qingrexiaoyanning dripping pills can be ...

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PUM

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Abstract

A Chinese medicine in the form of dripping pill for treating influenza, pharyngolaryngitis, pneumonia, bacterial dysentery, acute enterogastritis, appendicitis, etc is prepared from glabrous sarcandra herb and matrix.

Description

technical field [0001] The invention relates to a kind of medicine which has the functions of clearing heat and detoxifying, reducing inflammation and relieving pain, relaxing tendons and activating collaterals, and is used for treating diseases such as influenza, pharyngitis, pneumonia, bacillary dysentery, acute gastroenteritis, appendicitis, burn, sore abscess, cellulitis and the like. A pharmaceutical composition, in particular to a pharmaceutical composition oral drop pill preparation prepared from Jiujie tea as a raw material of traditional Chinese medicine. Background technique [0002] According to the ministerial drug standard WS 3 -Qingre Xiaoyanning Capsule prepared by the preparation method given in B-1842-94 is a kind of capsule with heat-clearing and detoxifying, anti-inflammatory and analgesic effects, and is used for the treatment of influenza, pharyngitis, pneumonia, bacillary dysentery, acute gastrointestinal Oral pharmaceutical preparations for diseases s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/185A61P11/04A61P1/12A61P17/02A61P31/04A61K127/00A61K135/00
CPCY02A50/30
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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